Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 70384-51-9, name is Tris(2-(2-methoxyethoxy)ethyl)amine, A new synthetic method of this compound is introduced below., COA of Formula: C15H33NO6
EXAMPLE 61 8-(3,5-Bis-trifluoromethyl-benzoyl)-3-(6-chloro-pyrimidin-4-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one A mixture of 8-(3,5-bis-trifluoromethyl-benzoyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one (0.1 g, 0.21 mmol), potassium carbonate (59 mg, 0.42 mmol), CuCl (2 mg, 0.021 mmol), tris[2-(2-methoxyethoxy)-ethyl]-amine (1.5 muL) and 4,6-dichloropyrimidine (32 mg, 0.21 mmol) in xylene (5 mL) was stirred and boiled for 18 h. The mixture was cooled, washed with water, ammonia in water (10percent) and water again. Evaporation of the solvent yielded a residue which was purified by chromatography on silica gel (ethyl acetate/n-hexane 1:2) to yield the desired product (29 mg, 24percent), m.p. 212-214° C. and MS: m/e=584.1 (M+H+).
The synthetic route of 70384-51-9 has been constantly updated, and we look forward to future research findings.