Category: ethers-buliding-blocks

Zhuang, Xiuzheng published the artcileSelective catalysis for the reductive amination of furfural toward furfurylamine by graphene-co-shelled cobalt nanoparticles, Application In Synthesis of 6850-57-3, the publication is Green Chemistry (2022), 24(1), 271-284, database is CAplus.

Amines with functional groups are widely used in the manufacture of pharmaceuticals, agricultural chems., and polymers but most of them are still prepared through petrochem. routes. The sustainable production of amines from renewable resources, such as biomass, is thus necessary. For this reason, we developed an eco-friendly, simplified, and highly effective procedure for the preparation of a non-toxic heterogeneous catalyst based on earth-abundant metals, whose catalytic activity on the reductive amination of furfural or other derivatives (more than 24 examples) proved to be broadly available. More surprisingly, the cobalt-supported catalyst was found to be magnetically recoverable and reusable up to eight times with an excellent catalytic activity; on the other hand, the gram-scale tests catalyzed by the same catalyst exhibited the similar yield of the target products in comparison to its smaller scale, which was comparable to the com. noble-based catalysts. Further results from a series of anal. technologies involving XRD, XPS, TEM/mapping, and in situ FTIR revealed that the structural features of the catalyst are closely in relation to its catalytic mechanisms. In simple terms, the outer graphitic shell is activated by the electronic interaction as well as the induced charge redistribution, enabling the easy substitution of the -NH2 moiety toward functionalized and structurally diverse mols., even under very mild industrially viable and scalable conditions. Overall, this newly developed catalyst introduces the synthesis of amines from biomass-derived platforms with satisfactory selectivity and carbon balance, providing cost-effective and sustainable access to the wide applications of reductive amination.

Green Chemistry published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H5F3O3, Application In Synthesis of 6850-57-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Xia, Jiajin published the artcileDivergent Access to Polycyclic N-Heterocyclic Compounds through Büchner-Type Dearomatization Enabled Cycloisomerization of Diynamides under Gold Catalysis, HPLC of Formula: 6850-57-3, the publication is Organic Letters (2022), 24(23), 4298-4303, database is CAplus and MEDLINE.

Herein, an unprecedented gold-catalyzed oxidative Buechner-type cyclopropanation of diynamides was described to afford polycyclic N-heterocyclic products I [R¹ = mesyl, nosyl, tosyl; R² = Ph, 4-MeC₆H₄, 2-ClC₆H₄, etc.], II [R³ = Ph, 4-FC₆H₄, 4-BrC₆H₄, etc.], III [R⁴ = Ph, 3-thienyl, 2-ClC₆H₄, etc.] and IV [R⁵ = Ph, 3-ClC₆H₄, 3-BrC₆H₄, etc.; R⁶ = mesyl, tosyl]. By variation of the position of substituents on the Ph ring, a variety of compounds I, II, III, IV with challenging structural skeletons were obtained divergently.

Organic Letters published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C15H24O2, HPLC of Formula: 6850-57-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Gui, Honggang published the artcileCross-metathesis approach for stereocontrolled synthesis of the C1-C15 fragment of rhizopodin, COA of Formula: C21H37BO, the publication is Synlett (2014), 25(1), 138-142, database is CAplus.

The C1-C15 fragment of rhizopodin was synthesized through either Suzuki coupling reaction of vinyl iodide and vinyl boronate or cross-metathesis of a terminal olefin and a diene adduct in the presence of Hoveyda-Grubbs II catalyst.

Synlett published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, COA of Formula: C21H37BO.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Fu, Yao published the artcileFirst-Principle Predictions of Absolute pK_a‘s of Organic Acids in Dimethyl Sulfoxide Solution, Name: 2-Methoxyacetamide, the publication is Journal of the American Chemical Society (2004), 126(3), 814-822, database is CAplus and MEDLINE.

MP2/6-311++G(d,p) and B3LYP/6-311++G(2df,p) methods are able to predict the gas-phase acidities of various organic acids with a precision of 2.2 and 2.3 kcal/mol. A PCM cluster-continuum solvation method was developed that could predict the solvation free energies of various neutral, cationic, and anionic organic species in DMSO with a precision of âˆ?.0 kcal/mol. Using these carefully tested methods, the authors successfully predicted the pK_a‘s of 105 organic acids in DMSO with a precision of 1.7-1.8 pK_a units. The authors also predicted the pK_a‘s of a variety of organosilanes in DMSO for the first time using the newly developed methods. This study was one of the first that employed first-principle methods for calculating pK_a‘s of unrelated compounds in organic solutions

Journal of the American Chemical Society published new progress about 16332-06-2. 16332-06-2 belongs to ethers-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Ether, name is 2-Methoxyacetamide, and the molecular formula is C3H7NO2, Name: 2-Methoxyacetamide.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zeng, Bo published the artcileOn the origin of nitrogen-containing promoters in the cobalt-catalyzed methoxycarbonylation of epoxides, COA of Formula: C4H10O2, the publication is Applied Catalysis, A: General (2021), 118291, database is CAplus.

The detailed promotion mechanism of nitrogenous compounds in the cobalt-catalyzed methoxycarbonylation of epoxides has not been studied to date. Herein, we present the intrinsic correlation between nitrogenous promoters and activity and selectivity in the alkoxycarbonylation of epoxides by a comprehensive in situ IR spectroscopy and DFT studies. In situ IR spectroscopy confirmed the acid-base neutralization of the nitrogenous promoters and HCo(CO)₄, resulting in reduction of the acidity of the catalyst. With the reduced acid-derived activity for formation of ethers as byproducts, the selectivity of desired esters was increased. DFT calculations showed that a nitrogenous base could facilitate the methanolysis of cobalt-acyl species with lowered activation energy, which is considered to be the rate-determining step in the catalytic cycle. As a result, the reaction activity towards carbonylation was also improved by nitrogenous promoters. The present studies will provide new insights to the long-term confusing problems in epoxides carbonylation.

Applied Catalysis, A: General published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C5H6BNO2, COA of Formula: C4H10O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Hu, Weiyao published the artcileRapidly and mildly transferring anatase phase of graphene-activated TiO₂ to rutile with elevated Schottky barrier: Facilitating interfacial hot electron injection for Vis-NIR driven photocatalysis, Quality Control of 6850-57-3, the publication is Nano Research, database is CAplus.

Visible and even IR (IR) light-initiated hot electrons of graphene (Gr) catalysts are a promising driven power for green, safe, and sustainable H₂O₂ synthesis and organic synthesis without the limitation of bandgap-dominated narrow light absorption to visible light confronted by conventional photocatalyst. However, the life time of photogenerated hot electrons is too short to be efficiently used for various photocatalytic reactions. Here, we proposed a straightforward method to prolong the lifetime of photogenerated hot electrons from graphene by tuning the Schottky barrier at Gr/rutile interface to facilitate the hot electron injection. The rational design of Gr-coated TiO₂ heterojunctions with interface synergy-induced decrease in the formation energy of the rutile phase makes the phase transfer of TiO₂ support proceed smoothly and rapidly via ball milling. The optimized Gr/rutile dyad could provide a H₂O₂ yield of 1.05 mM·g^-1·h^-1 under visible light irradiation (λ â‰?400 nm), which is 30 times of the state-of-the-art noble-metal-free titanium oxide-based photocatalyst, and even achieves a H₂O₂ yield of 0.39 mM·g^-1·h^-1 on photoexcitation by near-IR-region light (âˆ?800 nm).

Nano Research published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, Quality Control of 6850-57-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhao, Lifeng published the artcileNovel hyperbranched polyphenylene vinylenes with nitro group: synthesis, characterization and photophysical properties, Safety of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene, the publication is Huazhong Shifan Daxue Xuebao, Ziran Kexueban (2013), 47(1), 63-67, database is CAplus.

Novel PPV derivates with nitro group were designed and successfully synthesized through Gilch reaction. The reaction intermediate and polymers were characterized by ¹H NMR, GPC and Elemental Anal. (EA). The photophysics properties, thermal property, electrochem. property were investigated, these polymers are soluble in common organic solvents and they have good thermal stability. The onset weights loss temperature of polymers were 386.6, 370.4 and 397.8°C for P₁, P₂ and P₃, resp. In comparison with the solution absorption spectra, the absorption bands of polymers (P₁, P₂ and P₃) in thin films were red-shifted. These polymers may be promising materials for solar cells.

Huazhong Shifan Daxue Xuebao, Ziran Kexueban published new progress about 146370-51-6. 146370-51-6 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 1-((2-Ethylhexyl)oxy)-4-methoxybenzene, and the molecular formula is C10H20N2O6S2, Safety of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Wei, Juan published the artcilePhenolic compositions and antioxidant activities of Hippophae tibetana and H. rhamnoides ssp. sinensis berries produced in Qinghai-Tibet Plateau, Computed Properties of 134-96-3, the publication is Food Chemistry: X (2022), 100397, database is CAplus.

Phenolic ingredients of Hippophae tibetana (Tib) and H. rhamnoides ssp. sinensis (Rha) berry from Qinghai-Tibet Plateau were identified by Ultra Performance Liquid Chromatog.-triple Quadrupole Tandem Mass Spectrometry. Results demonstrated that both of them possessed high levels of total phenolic and flavonoid, and compared to Tib, Rha berry exhibited higher contents. Moreover, flavonols was the most predominant subclass in Rha berry, flavonols and flavanols were the two most abundant subclasses in Tib berry. Among them, rutin and narcissin were present in the most abundant amounts in Rha berry, while (-)-epigallocatechin was the richest substance in Tib berry. Furthermore, both phenolic extracts of sea buckthorn berry exhibited strong in vitro and cellular antioxidant properties. Rha berry extract exhibited much stronger effects because of its higher levels of phenolic and flavonoid profiles. This finding proved that the Rha berry could serve as a food source for better health with great potential antioxidant activity.

Food Chemistry: X published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C7H16Cl2Si, Computed Properties of 134-96-3.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhao, Lifeng published the artcileNovel hyperbranched poly (phenylene vinylene) s containing four arms: Synthesis, characterization and properties of photophysics, Formula: C15H24O2, the publication is Huazhong Shifan Daxue Xuebao, Ziran Kexueban (2012), 46(1), 45-48, 100, database is CAplus.

Novel PPVs derivates were designed and successfully synthesized through Gilch reaction. The reaction intermediates and polymers were characterized by ¹H NMR, GC-MS or GPC and Elemental Anal. (EA). Their optical properties, thermal properties, electrochem. properties were investigated. These polymers were soluble in common organic solvents and they have good thermal stability. The onset weights loss temperature of the three polymers were found to be 371.7, 386.6 and 391.8°C for P₁, P₂ and P₃, resp. Compared with their spectra absorption in chloroform, the absorption bands of polymers P₁, P₂ and P₃ in thin films were red-shifted. These polymers would be promising materials for luminescent materials or solar cells.

Huazhong Shifan Daxue Xuebao, Ziran Kexueban published new progress about 146370-51-6. 146370-51-6 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 1-((2-Ethylhexyl)oxy)-4-methoxybenzene, and the molecular formula is C3H6O2, Formula: C15H24O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Xiaohui published the artcileEfficient and practical catalyst-free-like dehydrative N-alkylation of amines and sulfinamides with alcohols initiated by aerobic oxidation of alcohols under air, Application of N-(4-Methoxybenzyl)pyridin-2-amine, the publication is Tetrahedron (2016), 72(2), 264-272, database is CAplus.

We developed simple and practical N-alkylation reactions of amines and sulfinamides with primary and secondary alcs. by using only catalytic amounts of air as the initiator without adding any external catalysts. This method has advantages of simple conditions, easy operation, and comparatively wider scope of substrates, providing an efficient and green catalyst-free-like alc.-based dehydrative N-alkylation method. Mechanistic studies revealed that air initiated the reactions by aerobic oxidation of the alcs. to the key initiating aldehydes or ketones in the presence of bases.

Tetrahedron published new progress about 52818-63-0. 52818-63-0 belongs to ethers-buliding-blocks, auxiliary class Pyridine,Amine,Benzene,Ether, name is N-(4-Methoxybenzyl)pyridin-2-amine, and the molecular formula is C13H14N2O, Application of N-(4-Methoxybenzyl)pyridin-2-amine.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem