Category: ethers-buliding-blocks

Intra-injector formation of methyl esters from phenoxy acid pesticides was written by Brondz, Ilia;Olsen, Ingar. And the article was included in Journal of Chromatography in 1992.Quality Control of 2-(4-Methoxyphenoxy)acetic acid This article mentions the following:

Trimethylanilinium hydroxide was used as a derivatization agent for a broad range of phenoxy acids. Derivatization took place inside the injector immediately before gas chromatog. anal., thereby minimizing the chance of exposing the operator to trimethylanilinium hydroxide. The reproducibility and sensitivity of the derivatization procedure were high. Maximum sensitivity for 19 phenoxy acids was 0.1-0.3 ppm. Derivatization was quant. and did not produce byproducts. The procedure required a min. of time and effort compared with other derivatization methods in current use and is recommended for routine determinations of phenoxy acids. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Quality Control of 2-(4-Methoxyphenoxy)acetic acid).

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Quality Control of 2-(4-Methoxyphenoxy)acetic acid

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ruthenium-Catalyzed Vinylene Carbonate Annulation by C-H/N-H Functionalizations: Step-Economical Access to Indoles was written by Yu, Yao;Wang, Yang;Li, Bo;Tan, Yuqiang;Zhao, Huan;Li, Zheyu;Zhang, Chunran;Ma, Wenbo. And the article was included in Advanced Synthesis & Catalysis in 2022.Formula: C12H17NO2 This article mentions the following:

A convenient and effective method of ruthenium-catalyzed C-H/N-H annulations using vinylene carbonate as oxidizing acetylene surrogate has been disclosed. This method is scalable and compatible with a wide range of functional groups, providing a step-economical access to indoles I (R = H, 5-Me, 7-Ph, 6-Br, etc.) and preliminary mechanistic studies provided support for a reversible, acetate-assisted C-H ruthenation, along with a subsequent olefin insertion. In the experiment, the researchers used many compounds, for example, N-(3-Methoxyphenyl)pivalamide (cas: 56619-93-3Formula: C12H17NO2).

N-(3-Methoxyphenyl)pivalamide (cas: 56619-93-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Formula: C12H17NO2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Electrochemically Induced Spirolactonization of α-(Methoxyphenoxy)alkanoic Acids into Quinone Ketals was written by Deffieux, Denis;Fabre, Isabelle;Courseille, Christian;Quideau, Stephane. And the article was included in Journal of Organic Chemistry in 2002.Quality Control of 2-(4-Methoxyphenoxy)acetic acid This article mentions the following:

Anodic oxidations of two series of α-(2-methoxyphenoxy)- and α-(4-methoxyphenoxy)alkanoic acids were studied both at the anal. and preparative scales in order to delineate mechanistic aspects of electrochem. induced spirolactonization and to develop synthetically useful orthoquinone bis- and monoketals. Although α-monomethylated carboxylic acids and acetic acid derivatives do not undergo any spiroannulation, α-dimethylated carboxylic acids furnished spirolactones in high yields. A gem-di-Me effect is invoked to explain these differences in cyclization capacity. Electrooxidation conditions can be selected to furnish quinone spirolactone bis- or monoketals. Chemoselective monohydrolysis of bisketals can also be accomplished in a stepwise fashion to furnish the corresponding spirolactone monoketals, but the ortho compound unfortunately dimerized in situ via a Diels-Alder process. An ECEC pathway is proposed to rationalize the observed spirolactonizations on the basis of cyclic voltammetry analyses. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Quality Control of 2-(4-Methoxyphenoxy)acetic acid).

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Quality Control of 2-(4-Methoxyphenoxy)acetic acid

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Analysis of organic pollutants in a wastewater treatment plant was written by Lepri, Luciano;Desideri, Piergiorgio;Del Bubba, Massimo. And the article was included in Annali di Chimica (Rome) in 1997.Quality Control of 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol This article mentions the following:

A comprehensive anal. method to identify and quant. determine organic pollutants in domestic and industrial wastewater collected during different treatment phases at the Baciacavallo Plant, Prato, Italy, is outlined. Liquid-liquid extraction (LLE) with n-hexane and liquid-solid extraction (LSE) on a RP-18 column to recover a wide variety of dissolved compounds were evaluated. Organic extracts were divided into 4 fractions of increasing polarity by adsorption on silica gel and analyzed using HPLC and high resolution gas chromatog.-mass spectrometry. The distribution of these pollutants between dissolved and particulate phases and their fate during treatment are discussed. In the experiment, the researchers used many compounds, for example, 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol (cas: 20324-33-8Quality Control of 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol).

1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol (cas: 20324-33-8) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Quality Control of 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Chemical constituents of volatile oil from Hubei lancea by three processing methods was written by Zhang, Hu;Xia, Xin-zhong;Xiang, Li-juan;Mao, Kun. And the article was included in Zhongguo Shiyan Fangjixue Zazhi in 2015.Product Details of 605-94-7 This article mentions the following:

Objective: Anal. and comparison of Hubei Mao herb fried gluten, rice water broiled, fried and other three kinds of different processing methods in the chem. composition of volatile oil. Methods: Application of steam distillation to extract three different processing methods of Hubei lancea volatile constituents by GC-MS anal. and identification of the chem. composition, and the use of peak area normalization method to calculate the relative quality of each component scores. Results: From three kinds, 88 kinds of volatile oil components were separated, 87 kinds of volatile chem. composition were identified, their common ingredients were 51 kinds, and the identified chem. composition of each sample on average accounted for 94.61% of total volatile oil. Conclusion: There are some differences between three kinds of Hubei lancea volatile chem. composition and contents of the different processing methods. In the experiment, the researchers used many compounds, for example, 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7Product Details of 605-94-7).

2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Product Details of 605-94-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Palladium-Catalyzed Dual Annulation: A Method for the Synthesis of Norneocryptolepine was written by Yeh, Li-Hsuan;Wang, Hung-Kai;Pallikonda, Gangaram;Ciou, Yu-Lun;Hsieh, Jen-Chieh. And the article was included in Organic Letters in 2019.Electric Literature of C8H9NO3 This article mentions the following:

A novel procedure for the Pd-catalyzed dual annulation reaction of I and derivatives to synthesize the norneocryptolepine derivatives involving the concerted construction of two central heterocycles is reported. The further methylation of norneocryptolepine (II) to afford its alkaloid analog neocryptolepine implies that synthesis of various neocryptolepine derivatives is feasible. The oxidative addition of Pd(0) is indicated as the key step to activate the intramol. addition of nitrile according to the mechanism study. In the experiment, the researchers used many compounds, for example, 3-Methyl-4-nitroanisole (cas: 5367-32-8Electric Literature of C8H9NO3).

3-Methyl-4-nitroanisole (cas: 5367-32-8) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Electric Literature of C8H9NO3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Towards a High-Performance Lithium-Metal Battery with Glyme Solution and an Olivine Cathode was written by Wei, Shuangying;Inoue, Shoichi;Di Lecce, Daniele;Li, Zhenguang;Tominaga, Yoichi;Hassoun, Jusef. And the article was included in ChemElectroChem in 2020.Name: 2,5,8,11-Tetraoxadodecane This article mentions the following:

High-performance lithium-metal batteries are achieved by using a glyme-based electrolyte enhanced with a LiNO₃ additive and a LiFePO₄ cathode. An optimal electrolyte formulation is selected upon detailed anal. of the electrochem. properties of various solutions formed by dissolving resp. lithium bis(fluorosulfonyl)imide (LiFSI), lithium bis(trifluoromethanesulfonyl)imide (LiTFSI), and lithium bis(pentafluoroethanesulfonyl)imide (LiBETI) either in diethylene glycol di-Me ether or in triethylene glycol di-Me ether and by adding LiNO₃. A thorough investigation shows evidence of efficient ionic transport, a wide stability window, low reactivity with lithium metal, and cathode/electrolyte interphase characteristics that are strongly dependent on the glyme chain length. The best Li/LiFePO₄ battery delivers 154 mAh g^-1 at C/3 (1 C=170 mA g^-1) without any decay after 200 cycles. Tests at 1 C and 5 C show initial capacities of about 150 and 140 mAh g^-1, a retention exceeding 70% after 500 cycles, and suitable electrode/electrolyte interphases evolution. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2Name: 2,5,8,11-Tetraoxadodecane).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Name: 2,5,8,11-Tetraoxadodecane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis and plant growth retardant activity of trialkylammonium iodides containing an aromatic ether moiety was written by Sharma, M. L.;Rani, Geeta;Talwar, K. K.;Kalsi, P. S.. And the article was included in Journal of the Indian Chemical Society in 1991.Synthetic Route of C9H10O4 This article mentions the following:

Alkyldimethyl(2-phenoxyethyl)ammonium iodides 4-R¹C₆H₄OCHR²CH₂NR³Me₂I (I; R¹ = H, MeO; R² = H, Me; R³ = Me, Et) were prepared from phenoxyacetic acid derivatives by chlorination and amidation to give amides, subsequent reduction of the latter and quaternization. I were effective as growth inhibitors for Brassica rapa. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Synthetic Route of C9H10O4).

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Synthetic Route of C9H10O4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Kinetics and mechanism of chlorination of phenoxyacetic acids by N-chloro-3-methyl-2,6-diphenylpiperidin-4-one was written by Kabilan, S.;Sankar, P.;Krishnasamy, K.. And the article was included in Oxidation Communications in 1994.Category: ethers-buliding-blocks This article mentions the following:

Chlorination of phenoxyacetic acid and several of its meta- and para-substituted derivatives by N-chloro-3-methyl-2,6-diphenylpiperidin-4-one yields monochlorinated product through a direct rate limiting attack at the ortho-carbon. The reaction is first order with respect to [substrate] and [oxidant]. Increase in [H⁺] and [Cl^–] increases the rate of reaction. The reaction rate does not show any significant change with an increase in ethanol content of the medium. The reaction is inhibited by added piperidone. The mechanistic pathways of the reaction have been discussed and substantiated through multiparameter correlation anal. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Category: ethers-buliding-blocks).

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Fe₃O₄@CS-Ni: An efficient and recyclable magnetic nanocatalyst for α-alkylation of ketones with benzyl alcohols by borrowing hydrogen methodology was written by Taheri-Torbati, Mina;Eshghi, Hossein. And the article was included in Applied Organometallic Chemistry in 2022.SDS of cas: 105-13-5 This article mentions the following:

This paper reports a heterogeneous magnetic impressive nickel catalyst in which Fe₃O₄ nanoparticles have been coated with chitosan and decorated with nickel nanoparticles (Fe₃O₄@CS-Ni). This catalyst has been used for direct α-alkylation of aryl ketones with substituted benzyl alcs. through borrowing hydrogen and dehydrogenation mechanism that affords the corresponding α-benzyl ketones, with good to excellent yield. The core-shell morphol. has been confirmed with different anal. techniques such as Fourier-transform IR (FT-IR), X-ray diffraction (XRD), vibrating sample magnetometer (VSM), SEM (SEM), transmission electron microscopy (TEM), SEM mapping, energy-dispersive X-ray (EDX), inductively coupled plasma (ICP), and thermogravimetric anal. (TGA). Moreover, the catalyst could be recovered from the reaction mixture by using an external magnetic field and reused for six successive cycles without a considerable decrease in catalytic activity. In the experiment, the researchers used many compounds, for example, (4-Methoxyphenyl)methanol (cas: 105-13-5SDS of cas: 105-13-5).

(4-Methoxyphenyl)methanol (cas: 105-13-5) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.SDS of cas: 105-13-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem