Braga Emidio, Nayara team published research on Journal of Medicinal Chemistry in 2021 | 73724-45-5

73724-45-5, Fmoc-Ser-OH, also known as Fmoc-Ser-OH, is a useful research compound. Its molecular formula is C18H17NO5 and its molecular weight is 327.3 g/mol. The purity is usually 95%.
Fmoc-L-Ser-OH is a synthetic peptide that belongs to the group of glycopeptides. It is used as a model for such compounds and has been shown to have antimicrobial activity in vitro against gram-positive bacteria, especially Staphylococcus epidermidis. This compound was synthesized from 3-mercaptopropionic acid and chloride in the presence of hydroxyl groups and epidermal growth factor. The synthetic pathway can be divided into three steps: (1) condensation of 3-mercaptopropionic acid with hydrochloric acid to yield 3-mercaptoacrylic acid; (2) esterification of 3-mercaptoacrylic acid with glycine to form Fmoc-L-Ser; and (3) deprotection of Fmoc protecting group., Synthetic Route of 73724-45-5

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 73724-45-5, formula is C18H17NO5, Name is Fmoc-Ser-OH.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Synthetic Route of 73724-45-5.

Braga Emidio, Nayara;Meli, Rajeshwari;Tran, Hue N. T.;Baik, Hayeon;Morisset-Lopez, Severine;Elliott, Alysha G.;Blaskovich, Mark A. T.;Spiller, Sabrina;Beck-Sickinger, Annette G.;Schroeder, Christina I.;Muttenthaler, Markus research published 《 Chemical synthesis of TFF3 reveals novel mechanistic insights and a gut-stable metabolite》, the research content is summarized as follows. TFF3 regulates essential gastro- and neuroprotective functions, but its mol. mode of action remains poorly understood. Synthetic intractability and lack of reliable bioassays and validated receptors are bottlenecks for mechanistic and structure-activity relationship studies. Here, we report the chem. synthesis of TFF3 and its homodimer via native chem. ligation followed by oxidative folding. Correct folding was confirmed by NMR and CD, and TFF3 and its homodimer were not cytotoxic or hemolytic. TFF3, its homodimer, and the trefoil domain (TFF310-50) were susceptible to gastrointestinal degradation, revealing a gut-stable metabolite (TFF37-54; t1/2 > 24 h) that retained its trefoil structure and antiapoptotic bioactivity. We tried to validate the putative TFF3 receptors CXCR4 and LINGO2, but neither TFF3 nor its homodimer displayed any activity up to 10μM. The discovery of a gut-stable bioactive metabolite and reliable synthetic accessibility to TFF3 and its analogs are cornerstones for future mol. probe development and structure-activity relationship studies.

73724-45-5, Fmoc-Ser-OH, also known as Fmoc-Ser-OH, is a useful research compound. Its molecular formula is C18H17NO5 and its molecular weight is 327.3 g/mol. The purity is usually 95%.
Fmoc-L-Ser-OH is a synthetic peptide that belongs to the group of glycopeptides. It is used as a model for such compounds and has been shown to have antimicrobial activity in vitro against gram-positive bacteria, especially Staphylococcus epidermidis. This compound was synthesized from 3-mercaptopropionic acid and chloride in the presence of hydroxyl groups and epidermal growth factor. The synthetic pathway can be divided into three steps: (1) condensation of 3-mercaptopropionic acid with hydrochloric acid to yield 3-mercaptoacrylic acid; (2) esterification of 3-mercaptoacrylic acid with glycine to form Fmoc-L-Ser; and (3) deprotection of Fmoc protecting group., Synthetic Route of 73724-45-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Brousseau, Margaret E. team published research on Cell Chemical Biology in 2022 | 73724-45-5

SDS of cas: 73724-45-5, Fmoc-Ser-OH, also known as Fmoc-Ser-OH, is a useful research compound. Its molecular formula is C18H17NO5 and its molecular weight is 327.3 g/mol. The purity is usually 95%.
Fmoc-L-Ser-OH is a synthetic peptide that belongs to the group of glycopeptides. It is used as a model for such compounds and has been shown to have antimicrobial activity in vitro against gram-positive bacteria, especially Staphylococcus epidermidis. This compound was synthesized from 3-mercaptopropionic acid and chloride in the presence of hydroxyl groups and epidermal growth factor. The synthetic pathway can be divided into three steps: (1) condensation of 3-mercaptopropionic acid with hydrochloric acid to yield 3-mercaptoacrylic acid; (2) esterification of 3-mercaptoacrylic acid with glycine to form Fmoc-L-Ser; and (3) deprotection of Fmoc protecting group., 73724-45-5.

Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 73724-45-5, formula is C18H17NO5, Name is Fmoc-Ser-OH. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. SDS of cas: 73724-45-5.

Brousseau, Margaret E.;Clairmont, Kevin B.;Spraggon, Glen;Flyer, Alec N.;Golosov, Andrei A.;Grosche, Philipp;Amin, Jakal;Andre, Jerome;Burdick, Debra;Caplan, Shari;Chen, Guanjing;Chopra, Raj;Ames, Lisa;Dubiel, Diana;Fan, Li;Gattlen, Raphael;Kelly-Sullivan, Dawn;Koch, Alexander W.;Lewis, Ian;Li, Jingzhou;Liu, Eugene;Lubicka, Danuta;Marzinzik, Andreas;Nakajima, Katsumasa;Nettleton, David;Ottl, Johannes;Pan, Meihui;Patel, Tajesh;Perry, Lauren;Pickett, Stephanie;Poirier, Jennifer;Reid, Patrick C.;Pelle, Xavier;Seepersaud, Mohindra;Subramanian, Vanitha;Vera, Victoria;Xu, Mei;Yang, Lihua;Yang, Qing;Yu, Jinghua;Zhu, Guoming;Monovich, Lauren G. research published 《 Identification of a PCSK9-LDLR disruptor peptide with in vivo function》, the research content is summarized as follows. Proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates plasma low-d. lipoprotein cholesterol (LDL-C) levels by promoting hepatic LDL receptor (LDLR) degradation Therapeutic antibodies that disrupt PCSK9-LDLR binding reduce LDL-C concentrations and cardiovascular disease risk. The epidermal growth factor precursor homol. domain A (EGF-A) of the LDLR serves as a primary contact with PCSK9 via a flat interface, presenting a challenge for identifying small mol. PCSK9-LDLR disruptors. We employ an affinity-based screen of 1013in vitro-translated macrocyclic peptides to identify high-affinity PCSK9 ligands that utilize a unique, induced-fit pocket and partially disrupt the PCSK9-LDLR interaction. Structure-based design led to mols. with enhanced function and pharmacokinetic properties (e.g., 13PCSK9i). In mice, 13PCSK9i reduces plasma cholesterol levels and increases hepatic LDLR d. in a dose-dependent manner. 13PCSK9i functions by a unique, allosteric mechanism and is the smallest mol. identified to date with in vivo PCSK9-LDLR disruptor function.

SDS of cas: 73724-45-5, Fmoc-Ser-OH, also known as Fmoc-Ser-OH, is a useful research compound. Its molecular formula is C18H17NO5 and its molecular weight is 327.3 g/mol. The purity is usually 95%.
Fmoc-L-Ser-OH is a synthetic peptide that belongs to the group of glycopeptides. It is used as a model for such compounds and has been shown to have antimicrobial activity in vitro against gram-positive bacteria, especially Staphylococcus epidermidis. This compound was synthesized from 3-mercaptopropionic acid and chloride in the presence of hydroxyl groups and epidermal growth factor. The synthetic pathway can be divided into three steps: (1) condensation of 3-mercaptopropionic acid with hydrochloric acid to yield 3-mercaptoacrylic acid; (2) esterification of 3-mercaptoacrylic acid with glycine to form Fmoc-L-Ser; and (3) deprotection of Fmoc protecting group., 73724-45-5.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Buchstaller, Hans-Peter team published research on Bioorganic & Medicinal Chemistry Letters in 2012 | 38256-93-8

Reference of 38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine.They have the general formula R–O–R′, where R and R′ represent the alkyl or aryl groups. Reference of 38256-93-8.

Buchstaller, Hans-Peter;Eggenweiler, Hans-Michael;Sirrenberg, Christian;Graedler, Ulrich;Musil, Djordje;Hoppe, Edmund;Zimmermann, Astrid;Schwartz, Harry;Maerz, Joachim;Bomke, Joerg;Wegener, Ansgar;Wolf, Michael research published 《 Fragment-based discovery of hydroxy-indazole-carboxamides as novel small molecule inhibitors of Hsp90》, the research content is summarized as follows. Inhibitors of the Hsp90 mol. chaperone are showing considerable promise as potential mol. therapeutic agents for the treatment of cancer. Here we describe the identification of novel small mol. weight inhibitors of Hsp90 using a fragment based approach. Fragments were selected by docking, tested in a biochem. assay and the confirmed hits were crystallized Information gained from X-ray structures of these fragments and other chemotypes was used to drive the fragment evolution process. Optimization of these high μM binders resulted in 3-benzylindazole derivatives with significantly improved affinity and anti-proliferative effects in different human cancer cell lines.

Reference of 38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., 38256-93-8.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Choi, Young Chul et al. published new progress in experiments with the help of cas: 2657-87-6

3-(4-Aminophenoxy)aniline is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. Product Details of 2657-87-6 The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.

Choi, Young Chul;Kim, Min Su;Ryu, Kyoung Moon;Lee, Sang Hoon;Jeong, Young Gyu published 《Synthesis and Characterization of Aromatic Poly(azomethine ether)s with Different meta- and para-Phenylene Linkage Contents》. The research results were published in《Fibers and Polymers》 in 2020.Product Details of 2657-87-6 The article conveys some information:

New aromatic poly(azomethine ether)s (PAMEs) bearing different meta- and para-phenylene linkage ratios in the main chains were synthesized via solution polycondensation reactions of terephthalaldehyde and/or isophthaldehyde with 3,4′-diaminodiphenyl ether. The mol. structures, thermal stability, thermo-mech. and optical properties of the synthesized PAME homopolymers and copolymers were investigated by using FT-IR, TGA, DMA, and UV-visible/ fluorescence spectroscopy, resp. The synthesized PAMEs were characterized to be thermally stable up to ∼400° under nitrogen or air atm. and to have high char residues of above 55% at 800° under nitrogen condition. The DMA data revealed that the glass transition temperatures of PMAEs are in the range of 150-200°, depending on the relative contents of meta- and para-phenylene linkages. The maximum absorption wavelength of transparent yellowish PAME films was detected at 410 ±10 nm. In addition, all PAME films exhibited a broad visible emission band at 500-800 nm and two IR emission bands at 800-1400 nm. The synthesized PAMEs with high thermal stability and thermo-mech. performance can be thus used as functional polymeric materials for tech. fibers, optoelectronic films, and carbon fiber precursors.3-(4-Aminophenoxy)aniline (cas: 2657-87-6) were involved in the experimental procedure.

3-(4-Aminophenoxy)aniline is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. Product Details of 2657-87-6 The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Cas: 2657-87-6 was involved in experiment | Polymer 2019

3-(4-Aminophenoxy)aniline is one of ethers-buliding-blocks. Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. COA of Formula: C12H12N2OEthers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds.

COA of Formula: C12H12N2OIn 2019, Zhou, Dianrui;Yuan, Lili;Hong, Weijie;Zhang, Haoyang;Hu, Aijun;Yang, Shiyong published 《Molecular design of interpenetrating fluorinated polyimide network with enhanced high performance for heat-resistant matrix》. 《Polymer》published the findings. The article contains the following contents:

Novel reactive phenylethynyl-endcapped diluents were synthesized and phys. mixed with fluorinated cooligoimides (mol. weights of 5000 g/mol) derived from 4,4′-(hexafluoroisopropylidene)diphthalic anhydride (6FDA), 2,2′-bis(trifluoromethyl)-4,4′-diamino biphenyl (TFDB) and para-phenylenediamine (p-PDA) at 25/75 M ratio, and 4-phenylethyethynylphthalic anhydride (PEPA) to formulate blends served as matrix resins for developing high-performance composites with excellent processabilities. The uncured blend shows very low min. melt viscosity (<1 Pa s) and extended process window achieved using molten solvation of reactive diluent to prevent intermol. interactions and recrystallization at higher temperature This blend was converted to interpenetrating polyimide network through thermal-curing of phenylethynyl end-groups in each constituent. The morphol., relaxation transition and mech. property were investigated as functions of mass fraction and chem. configuration of reactive diluent. The covalent incorporation of crosslink structures restricts segmental motion while backbone linkage induces strength and toughness retention. This cooperative effect endows homogeneous networks with high glass transition temperatures (435 °C) and flexural strength (130 MPa) simultaneously.3-(4-Aminophenoxy)aniline (cas: 2657-87-6) were involved in the experimental procedure.

3-(4-Aminophenoxy)aniline is one of ethers-buliding-blocks. Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. COA of Formula: C12H12N2OEthers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds.

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Cas: 2657-87-6 was involved in experiment | Journal of Polymer Research 2018

3-(4-Aminophenoxy)aniline is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. HPLC of Formula: 2657-87-6 The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.

HPLC of Formula: 2657-87-6《Preparation of high temperature resistant Ag/PI/Cu composite nano particles inserted with PI insulating layer》 was published in 2018. The authors were Qu, Chunyan;Li, Liaoliao;Liu, Changwei;Wag, Dezhi;Xiao, Wanbano;Zhu, Guangyu;Cao, Zhibo;Li, Hongfeng;Su, Kai, and the article was included in《Journal of Polymer Research》. The author mentioned the following in the article:

Polyimide (PI)@copper (Cu) composite nano particles have been successfully synthesized from poly(amic acid) triethylamine salts (PAAS) and Cu(II) ions via a one-step high-temperature induction/imidization route. The formation of PI@Cu nano particles has been investigated by the stoichiometric ratio of PAAS and Cu ion. The resulting products, formed stable shell-core structures, exhibited the uniform core-size and thick shell layer. Addnl., the multi-layer structure, Ag@PI@Cu, was successfully prepared via a post process of PI@Cu nanoparticles. The morphol. of the formed “Sunflower-mode” structure, with the pistil of Cu, the sunflower seed of PI, and the petal of Ag, was also characterized by SEM and TEM. Both elec. resistivity and thermal conductivity of nano particles were measured. The coefficient of heat conduction of Ag@PI@Cu is even 255 times, 754 times, 3081 times, and 1310 times as large as PI@Cu in 50 °C, 100 °C, 150 °C, and 200 °C, resp. The resistance of both nano particles is that the result of RsPI/Cu and RsAg/PI/Cu is 11.0*109 ω and 0.11 ω, resp., and also the difference between them is more than 1012. And 3-(4-Aminophenoxy)aniline (cas: 2657-87-6) was used in the research process.

3-(4-Aminophenoxy)aniline is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. HPLC of Formula: 2657-87-6 The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Cas: 2235-01-0 | Kawabata, Tomonori et al. made new progress in 2003

Dimethoxydiphenylmethane is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. HPLC of Formula: 2235-01-0 The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.

Kawabata, Tomonori;Kato, Masaki;Mizugaki, Tomoo;Ebitani, Kohki;Kaneda, Kiyotomi published 《Highly efficient deprotection of acetals by titanium cation-exchanged montmorillonite as a strong solid acid catalyst》. The research results were published in《Chemistry Letters》 in 2003.HPLC of Formula: 2235-01-0 The article conveys some information:

Deprotection of various kinds of acetals proceeded efficiently in the presence of Ti4+-exchanged montmorillonite as a recyclable strong solid acid catalyst. Other metal-exchanged montmorillonites were also used in deprotection of dimethoxydiphenylmethane. To complete the study, the researchers used Dimethoxydiphenylmethane (cas: 2235-01-0) .

Dimethoxydiphenylmethane is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. HPLC of Formula: 2235-01-0 The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Cas: 2235-01-0 | Blumel, Marcuspublished an article in 2018

Dimethoxydiphenylmethane is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. Related Products of 2235-01-0 The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.

Blumel, Marcus;Nagasawa, Shota;Blackford, Katherine;Hare, Stephanie R.;Tantillo, Dean J.;Sarpong, Richmond published 《Rearrangement of Hydroxylated Pinene Derivatives to Fenchone-Type Frameworks: Computational Evidence for Dynamically-Controlled Selectivity》. The research results were published in《Journal of the American Chemical Society》 in 2018.Related Products of 2235-01-0 The article conveys some information:

An acid-catalyzed Prins/semipinacol rearrangement cascade reaction of hydroxylated pinene derivatives that leads to tricyclic fenchone-type scaffolds in very high yields and diastereoselectivity has been developed. Quantum chem. anal. of the selectivity-determining step provides support for the existence of an extremely flat potential energy surface around the transition state structure. This transition state structure appears to be ambimodal, i.e., the fenchone-type tricyclic scaffolds are formed in preference to the competing formation of a bornyl (camphor-type) skeleton under dynamic control via a post-transition state bifurcation (PTSB). And Dimethoxydiphenylmethane (cas: 2235-01-0) was used in the research process.

Dimethoxydiphenylmethane is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. Related Products of 2235-01-0 The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Mansilla, Horacio et al. published new progress in experiments with the help of cas: 2235-01-0

The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom.Reference of Dimethoxydiphenylmethane

Reference of Dimethoxydiphenylmethane《Iron(III) tosylate in the preparation of dimethyl and diethyl acetals from ketones and β-keto enol ethers from cyclic β-diketones》 was published in 2008. The authors were Mansilla, Horacio;Afonso, Maria M., and the article was included in《Synthetic Communications》. The author mentioned the following in the article:

An efficient method for conversion of ketones to their corresponding di-Me and di-Et acetals and of cyclic β-diketones into β-keto enol ethers using Fe(OTs)3 as a catalyst is described. To complete the study, the researchers used Dimethoxydiphenylmethane (cas: 2235-01-0) .

The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom.Reference of Dimethoxydiphenylmethane

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Explore more uses of cas: 2235-01-0 | Applied Organometallic Chemistry

Dimethoxydiphenylmethane is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. Name: Dimethoxydiphenylmethane The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.

Okano, Tamon;Michihashi, Tomonori;Kiji, Jitsuo published 《Acetalization of ketones and aldehydes catalyzed by lanthanoid trisulfonates》 in 1995. The article was appeared in 《Applied Organometallic Chemistry》. They have made some progress in their research.Name: Dimethoxydiphenylmethane The article mentions the following:

Lanthanoid sulfonates are good catalysts for the acetalization of aldehydes and ketones with Me orthoformate in methanol. The catalytic activity of Ln(OTf)3 (OTf = trifluoromethanesulfonate) increases in the order of La < Sm < Gd < Er < Yb. Since sulfonates such as trifluoromethylsulfonates and (1S)-10-camphorsulfonates are more soluble in organic solvents than the chlorides, the acetalization in ether or dichloromethane and the exchange reaction of alkoxy groups between acetals and alcs. can be achieved under mild conditions. And Dimethoxydiphenylmethane (cas: 2235-01-0) was used in the research process.

Dimethoxydiphenylmethane is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. Name: Dimethoxydiphenylmethane The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem