Bodner, Michaela et al. published their research in Biochemical Systematics and Ecology in 2018 | CAS: 605-94-7

2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Synthetic Route of C9H10O4

Chemotaxonomic potential of exocrine alkyl esters in julid millipedes (Diplopoda: Julidae: Cylindroiulini) was written by Bodner, Michaela;Vagalinski, Boyan;Raspotnig, Guenther. And the article was included in Biochemical Systematics and Ecology in 2018.Synthetic Route of C9H10O4 This article mentions the following:

There are numerous chemotaxonomic studies on arthropods, but such are largely missing for millipedes. This appears curious since particularly in millipedes, the major taxa are clearly distinctive by different exocrine products, such as alkaloids (Glomerida), terpenoids (Polyzoniida), phenolics and cyanogens (Polydesmida), and benzoquinones (Juliformia). However, there is low within-taxon variation of the chems. mentioned which – in almost invariable blends – characterize the particular taxa. The Julida, for instance, one of the three orders of Juliformia, typically produce uniformly composed benzoquinonic secretion profiles across most species, not showing enough heterogeneity for chemotaxonomy. Recently, however, a new class of julid exocrine products, namely complex bends of alkyl esters has been reported. We here tested the chemotaxonomic potential of these compounds by performing a comprehensive study on alkyl esters across the julid tribe Cylindroiulini. Exocrine secretions of 20 species from all five cylindroiuline genera (Allajulus, Cylindroiulus, Enantiulus, Kryphioiulus, Styrioiulus) were analyzed by gas chromatog. – mass spectrometry. Apart from typical benzoquinones, 33 alkyl esters and 1 alkenyl ester belonging to hexyl-, octyl-, octenyl- and nonyl-esters with saturated and mono-unsaturated acid moieties ranging from C13 – C18 were detected. Only two species (Cylindroiulus caeruleocinctus and C. luridus) exhibited no esters at all. Ester profiles appeared to be specific, indicating five major chem. groups in cylindroiulines, characterized by specific ester arrangements. We here provide evidence for (i) the widespread occurrence of alkyl esters in the Julidae, (ii) their high specificity, (iii) their intra-species stability, (iv) along with sufficient inter-species variability, rendering them promising novel tools for millipede chemotaxonomy. In the experiment, the researchers used many compounds, for example, 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7Synthetic Route of C9H10O4).

2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Synthetic Route of C9H10O4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ma, Mingxuan et al. published their research in Chromatographia in 2017 | CAS: 66943-05-3

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.HPLC of Formula: 66943-05-3

Preparation and Application of Aza-15-crown-5-capped Methylcalix[4]resorcinarene-Bonded Silica Particles for Use as Chiral Stationary Phase in HPLC was written by Ma, Mingxuan;Wei, Qunli;Meng, Min;Yin, Jiale;Shan, Yu;Du, Lei;Zhu, Xia;Soh, Shu Fang;Min, Mengjun;Zhou, Xueyan;Yin, Xiaoxing;Gong, Yinhan. And the article was included in Chromatographia in 2017.HPLC of Formula: 66943-05-3 This article mentions the following:

Abstract: Aza-15-crown-5-capped (3-(C-methylcalix[4]resorcinarene)-2-hydroxypropoxy)-propylsilyl (MCR-HP)-appended silica particles (15C5-MCR-HPS), a new type of substituted C-methylcalix[4]resorcinarene (MCR)-bonded chiral stationary phase (CSP) for high-performance liquid chromatog. (HPLC), have been synthesized by reaction of bromoacetate-substituted MCR-HPS with excessive aza-15-crown-5 in anhydrous acetonitrile in the presence of potassium carbonate. The bonded phase 15C5-MCR-HPS is characterized by elemental anal. and further evaluated by separating several disubstituted benzenes and some chiral drug compounds in HPLC. The new CSP has a chiral selector with two recognition sites: 15-crown-5 and MCR-HP, which can provide cooperative multiple interactions with solutes to enhance chiral recognition and to improve chromatog. separation The chromatog. evaluation results show that 15C5-MCR-HPS has excellent selectivity for the separation of aromatic positional isomers and enantiomers of some chiral compounds under multiple-mode mobile phase conditions including normal phase, reversed phase, and polar organic mobile phase conditions. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3HPLC of Formula: 66943-05-3).

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.HPLC of Formula: 66943-05-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ju, Yeming et al. published their research in Organic & Biomolecular Chemistry in 2015 | CAS: 5367-32-8

3-Methyl-4-nitroanisole (cas: 5367-32-8) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Computed Properties of C8H9NO3

Tandem catalytic oxidative deacetylation of acetoacetic esters and heteroaromatic cyclizations was written by Ju, Yeming;Miao, Di;Yu, Ruiyang;Koo, Sangho. And the article was included in Organic & Biomolecular Chemistry in 2015.Computed Properties of C8H9NO3 This article mentions the following:

One pot syntheses of furan, thiophene, and pyrrole were accomplished by oxidative deacetylation using Mn(III)/Co(II) catalysts and the Paal-Knorr reaction from 1,5-dicarbonyl compounds, which are prepared from the conjugate addition of Et acetoacetate to α,β-unsaturated carbonyl compounds The oxidative deacetylation and reductive cyclization of β-ketoesters derived from Et acetoacetate and o-nitrobenzyl bromides efficiently produced diversely substituted indoles. In the experiment, the researchers used many compounds, for example, 3-Methyl-4-nitroanisole (cas: 5367-32-8Computed Properties of C8H9NO3).

3-Methyl-4-nitroanisole (cas: 5367-32-8) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Computed Properties of C8H9NO3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Mendez, Jesus et al. published their research in Microchemical Journal in 1969 | CAS: 6972-61-8

3-(2,4-Dimethoxyphenyl)acrylic acid (cas: 6972-61-8) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Formula: C11H12O4

Spectral characterization of coumarins and cinnamic acids was written by Mendez, Jesus;Lojo, M. I.. And the article was included in Microchemical Journal in 1969.Formula: C11H12O4 This article mentions the following:

The wavelengths of maximum absorption (in the range 220-450 nm) are given for 6-hydroxy-, 4-methyl-6,7-dihydroxy -, 6-hydroxy-7-(β-D-glucopyranosyloxy)-, 6-methoxy-7-(β-D-glucopyranosyloxy]-, 6-methoxy-7-[(6-O-β-D-xylopyranosyl-β-D-glucopyranosyl)oxy]-, 7,8-dihydroxy-, 7-(β-D-glucopyranosyloxy)-8-hydroxy-coumarin, dihydroxy- and dimethoxycinnamic acids, 2-hydroxy-3-methoxycinnamic acid, Me 3,4,5-trimethoxycinnamate, and 3,4-dihydroxy-5-methoxycinnamic acid in MeOH and in MeOH solutions containing NaOAc, H3BO3, AlCl3, NaBH4, and NaOH. A structural correlation for the spectral data was obtained only for the 5 coumarins naturally occurring in plants. In the experiment, the researchers used many compounds, for example, 3-(2,4-Dimethoxyphenyl)acrylic acid (cas: 6972-61-8Formula: C11H12O4).

3-(2,4-Dimethoxyphenyl)acrylic acid (cas: 6972-61-8) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Formula: C11H12O4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Archer, John G. et al. published their research in Journal of the Chemical Society in 1973 | CAS: 5367-32-8

3-Methyl-4-nitroanisole (cas: 5367-32-8) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.HPLC of Formula: 5367-32-8

1,2,3-Benzotrianzin-4-ones and related systems. II. Thermolytic decomposition of substituted 1,2,3-benzotriazin-4-ones and isatoic anhydrides was written by Archer, John G.;Barker, Alan J.;Smalley, Robert K.. And the article was included in Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) in 1973.HPLC of Formula: 5367-32-8 This article mentions the following:

Thermolysis of substituted 1,2,3-benzotriazin-4-ones gave 2-(2-amino- phenyl)-3,1-benzoxazin-4-ones. Thus, 7-chloro-1,2,3-benzotriazin-4-one (I) gave 2-(2-amino-4-chloro- phenyl)-7-chloro-3,1-benzoxazin-4-one (II). Substituted isatoic anhydrides behaved similarly. In the experiment, the researchers used many compounds, for example, 3-Methyl-4-nitroanisole (cas: 5367-32-8HPLC of Formula: 5367-32-8).

3-Methyl-4-nitroanisole (cas: 5367-32-8) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.HPLC of Formula: 5367-32-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Yang, Zhenzhen et al. published their research in Frontiers in Chemistry (Lausanne, Switzerland) in 2022 | CAS: 112-49-2

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Quality Control of 2,5,8,11-Tetraoxadodecane

Toward practical issues: Identification and mitigation of the impurity effect in glyme solvents on the reversibility of Mg plating/stripping in Mg batteries was written by Yang, Zhenzhen;Yang, Mengxi;Hahn, Nathan T.;Connell, Justin;Bloom, Ira;Liao, Chen;Ingram, Brian J.;Trahey, Lynn. And the article was included in Frontiers in Chemistry (Lausanne, Switzerland) in 2022.Quality Control of 2,5,8,11-Tetraoxadodecane This article mentions the following:

Reversible electrochem. magnesium plating/stripping processes are important for the development of high-energy-d. Mg batteries based on Mg anodes. Ether glyme solutions such as monoglyme (G1), diglyme (G2), and triglyme (G3) with the MgTFSI2 salt are one of the conventional and commonly used electrolytes that can obtain the reversible behavior of Mg electrodes. However, the electrolyte cathodic efficiency is argued to be limited due to the enormous parasitic reductive decomposition and passivation, which is governed by impurities. In this work, a systematic identification of the impurities in these systems and their effect on the Mg deposition-dissolution processes is reported. The mitigation methods generally used for eliminating impurities are evaluated, and their beneficial effects on the improved reactivity are also discussed. By comparing the performances, we proposed a necessary conditioning protocol that can be easy to handle and much safer toward the practical application of MgTFSI2/glyme electrolytes containing impurities. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2Quality Control of 2,5,8,11-Tetraoxadodecane).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Quality Control of 2,5,8,11-Tetraoxadodecane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Jiang, Xiao-Yan et al. published their research in BioResources in 2016 | CAS: 57179-35-8

3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Recommanded Product: 3-Hydroxy-5-methoxybenzaldehyde

Experimental and theoretical studies on the pyrolysis mechanism of β-1-type lignin dimer model compound was written by Jiang, Xiao-Yan;Lu, Qiang;Ye, Xiao-Ning;Hu, Bin;Dong, Chang-Qing. And the article was included in BioResources in 2016.Recommanded Product: 3-Hydroxy-5-methoxybenzaldehyde This article mentions the following:

A β-1-type lignin dimer, 1,2-bis(3,5-dimethoxyphenyl)propane-1,3-diol was employed as a model compound in this study. The pyrolysis mechanisms and formation pathways of the pyrolytic products were investigated by using d. functional theory (DFT) calculations and anal. pyrolysis-gas chromatog./mass spectrometry (Py-GC/MS). Four possible initial pyrolysis mechanisms were proposed, including the Cα-Cβ homolysis mechanism and three concerted decomposition mechanisms (1, 2, and 3). Results indicated that the lignin dimer decomposed via two concerted decomposition mechanisms, forming 3,5-dimethoxybenzaldehyde, 1,3-dimethoxy-5-vinylbenzene, 3-hydroxy-5-methoxybenzaldehyde, and 3-methoxybenzaldehyde. 3,5-Dimethoxybenzaldehyde was the major product, accounting for greater than 50% of all pyrolytic products. In addition to the two concerted decomposition mechanisms, Cα-Cβ homolysis was a secondary pyrolysis mechanism during the lignin dimer pyrolysis process, and the pyrolytic products included 3,5-dimethoxybenzyl alc., 3,5-dimethoxyphenethyl alc., 1,3-dimethoxybenzene, and 1,3-dimethoxy-5-methylbenzene. A third concerted decomposition mechanism was judged to be the least likely pathway to occur because of the high activation energy requirement. In the experiment, the researchers used many compounds, for example, 3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8Recommanded Product: 3-Hydroxy-5-methoxybenzaldehyde).

3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Recommanded Product: 3-Hydroxy-5-methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ding, Yuyang et al. published their research in Bioorganic Chemistry in 2019 | CAS: 605-94-7

2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Related Products of 605-94-7

Rational design, synthesis and biological evaluation of ubiquinone derivatives as IDO1 inhibitors was written by Ding, Yuyang;Tang, Fei;Xue, Xiaoqian;Luo, Jinfeng;Hussain, Muzammal;Huang, Yanhui;Wang, Zhen;Jiang, Hao;Tu, Zhengchao;Zhang, Jiancun. And the article was included in Bioorganic Chemistry in 2019.Related Products of 605-94-7 This article mentions the following:

Indoleamine 2,3-dioxygenase 1 (IDO1) is an attractive therapeutic target for the treatment of cancer, chronic viral infections and neurol. disorders characterized by pathol. immune stimulation. Herein, a series of known metal-chelating ubiquinone derivatives were designed, synthesized and evaluated for the IDO1 inhibiting activities. The docking studies showed that the compounds I (R = Me or H, R1 = Ph, 3-MeC6H5, 3-OMeC6H5, etc.) and coenzyme-Q1 exhibited different binding modes to IDO1 protein. Among these compounds, the most active compound is I (R = H, R1 = 3-BrC6H5) with an IC50 of 0.13 μM in enzymic assay. The results reveal that a possible halogen bonding interaction between the bromine atom (3-Br) and Cys129 significantly enhances the inhibition activity against IDO1. This study provides structural insights of the interactions between ubiquinone analogs and IDO1 protein for the further modification and optimization. In the experiment, the researchers used many compounds, for example, 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7Related Products of 605-94-7).

2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Related Products of 605-94-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Gao, En et al. published their research in Journal of Natural Products in 2017 | CAS: 3929-47-3

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.COA of Formula: C11H16O3

Bioactive Asarone-Derived Phenylpropanoids from the Rhizome of Acorus tatarinowii Schott was written by Gao, En;Zhou, Zheng-Qun;Zou, Jian;Yu, Yang;Feng, Xiao-Lin;Chen, Guo-Dong;He, Rong-Rong;Yao, Xin-Sheng;Gao, Hao. And the article was included in Journal of Natural Products in 2017.COA of Formula: C11H16O3 This article mentions the following:

Eight new (1a/1b (I,II), 2a, 3a, 4a/4b, and 5a/5b) and seven known (2b, 3b, and 6-10) asarone-derived phenylpropanoids, a known asarone-derived lignan (12), and four known lignan analogs (11) and (13-15) were isolated from the rhizome of Acorus tatarinowii Schott. The structures were elucidated via comprehensive spectroscopic analyses, modified Mosher’s method, and quantum chem. calculations Compounds I-8 were present as enantiomers, and I-5 were successfully resolved via chiral-phase HPLC. Compounds I/II were the first cases of asarone-derived phenylpropanoids with an iso-Pr C-3 side-chain tethered to a benzene core from nature. Hypoglycemic, antioxidant, and AChE inhibitory activities of I-15 were assessed by the α-glucosidase inhibitory, ORAC, DPPH radical scavenging, and AChE inhibitory assays, resp. All compounds except 3a showed α-glucosidase inhibitory activity. Compound 3b has the highest α-glucosidase inhibitory effect with an IC50 of 80.6 μM (pos. drug acarbose IC50 of 442.4 μM). In the antioxidant assays, compounds 13-15 exhibited ORAC and DPPH radical scavenging activities. The results of the AChE inhibitory assay indicated that all compounds exhibited weak AChE inhibitory activities. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3COA of Formula: C11H16O3).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.COA of Formula: C11H16O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Onoda, Mitsuki et al. published their research in ChemistrySelect in 2022 | CAS: 105-13-5

(4-Methoxyphenyl)methanol (cas: 105-13-5) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Safety of (4-Methoxyphenyl)methanol

Dehydrogenative Esterification and Dehydrative Etherification by Coupling of Primary Alcohols Based on Catalytic Function Switching of an Iridium Complex was written by Onoda, Mitsuki;Fujita, Ken-ichi. And the article was included in ChemistrySelect in 2022.Safety of (4-Methoxyphenyl)methanol This article mentions the following:

In this study, a new catalytic function switching system: not only dehydrogenative esterification but also dehydrative etherification under environmentally friendly conditions were accomplished by the employment of a single iridium catalyst based on catalytic function switching was successfully developed. Using benzyl alc. as a starting material, the esterification product, benzyl benzoate, and the etherification product, dibenzyl ether, were obtained in 92% and 89% yields, resp., by employing same iridium catalyst precursor bearing a dihydroxybipyridine ligand, under optimized conditions. In the experiment, the researchers used many compounds, for example, (4-Methoxyphenyl)methanol (cas: 105-13-5Safety of (4-Methoxyphenyl)methanol).

(4-Methoxyphenyl)methanol (cas: 105-13-5) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Safety of (4-Methoxyphenyl)methanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem