Ethers-buliding-blocks

Red-Emitting Fluorescence Sensors for Metal Cations: The Role of Counteranions and Sensing of SCN^– in Biological Materials was written by Lochman, Lukas;Machacek, Miloslav;Miletin, Miroslav;Uhlirova, Stepanka;Lang, Kamil;Kirakci, Kaplan;Zimcik, Petr;Novakova, Veronika. And the article was included in ACS Sensors in 2019.Name: 1,4,7,10-Tetraoxa-13-azacyclopentadecane This article mentions the following:

The spatiotemporal sensing of specific cationic and anionic species is crucial for understanding the processes occurring in living systems. Herein, the authors developed new fluorescence sensors derived from tetrapyrazinoporphyrazines (TPyzPzs) with a recognition moiety that consists of an aza-crown and supporting substituents. Their sensitivity and selectivity were compared by fluorescence titration experiments with the properties of known TPyzPzs (with either one aza-crown moiety or two of these moieties in a tweezer arrangement). Method of standard addition was employed for analyte quantification in saliva. For K⁺ recognition, the new derivatives had comparable or larger association constants with larger fluorescence enhancement factors compared to that with one aza-crown. Their fluorescence quantum yields in the ON state were 18× higher than that of TPyzPzs with a tweezer arrangement. Importantly, the sensitivity toward cations was strongly dependent on counteranions and increased as follows: NO₃^– < Br^– < CF₃SO₃^– < ClO₄^– â‰?SCN^–. This trend resembles the chaotropic ability expressed by the Hofmeister series. The high selectivity toward KSCN was explained by synergic association of both K⁺ and SCN^– with TPyzPz sensors. The sensing of SCN^– was further exploited in a proof of concept study to quantify SCN^– levels in the saliva of a smoker and to demonstrate the sensing ability of TPyzPzs under in vitro conditions. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3Name: 1,4,7,10-Tetraoxa-13-azacyclopentadecane).

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Name: 1,4,7,10-Tetraoxa-13-azacyclopentadecane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Rhodium-Catalyzed Oxidative Annulation of (2-Arylphenyl)boronic Acids with Alkynes: Selective Synthesis of Phenanthrene Derivatives was written by Nagata, Tomoya;Satoh, Tetsuya;Nishii, Yuji;Miura, Masahiro. And the article was included in Synlett in 2016.Computed Properties of C6H10O2 This article mentions the following:

A rhodium-catalyzed annulative coupling of (2-arylphenyl)boronic acids with alkynes has been developed for the facile construction of phenanthrene frameworks. The reaction proceeded without external bases, and dioxygen worked as a terminal oxidant. Deuterium-labeling experiments indicated the involvement of five-membered rhodacycle intermediates. In the experiment, the researchers used many compounds, for example, 1,4-Dimethoxy-2-butyne (cas: 16356-02-8Computed Properties of C6H10O2).

1,4-Dimethoxy-2-butyne (cas: 16356-02-8) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Computed Properties of C6H10O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

A General Method to Diverse Cinnolines and Cinnolinium Salts was written by Zhao, Dongbing;Wu, Qian;Huang, Xiaolei;Song, Feijie;Lv, Taiyong;You, Jingsong. And the article was included in Chemistry – A European Journal in 2013.Quality Control of 1,4-Dimethoxy-2-butyne This article mentions the following:

Cinnolines and cinnolinium salts represent pharmaceutically and biol. important structures with anticancer, antimicrobial, antiinflammatory, antiparasitic, trypanocidal, and foliar herbicide activities as well as structural motifs with optical and luminescent characteristics. In this work, a highly efficient and general method to create both cinnoline and cinnolinium frameworks through the rhodium(III)-catalyzed oxidative C-H activation/cyclization of azo compounds with alkynes has been developed which exhibits an unprecedented capacity to install versatile functional groups at various positions of the cinnoline ring. The catalytic protocol could be also extended to synthesize polycyclic cinnolinium salts, e.g., I (X-rays single crystal structure shown), through twice ortho-directed C-H activation and cyclization. In the experiment, the researchers used many compounds, for example, 1,4-Dimethoxy-2-butyne (cas: 16356-02-8Quality Control of 1,4-Dimethoxy-2-butyne).

1,4-Dimethoxy-2-butyne (cas: 16356-02-8) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Quality Control of 1,4-Dimethoxy-2-butyne

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Using a Chloride-Free Magnesium Battery Electrolyte to Form a Robust Anode-Electrolyte Nanointerface was written by Horia, Raymond;Nguyen, Dan-Thien;Eng, Alex Yong Sheng;Seh, Zhi Wei. And the article was included in Nano Letters in 2021.COA of Formula: C8H18O4 This article mentions the following:

Magnesium bis(hexamethyldisilazide) (Mg(HMDS)₂)-based electrolytes are compelling candidates for rechargeable magnesium batteries due to their high compatibility with magnesium metal anode. However, the usual combination of Mg(HMDS)₂ with chloride salts limits their practical application due to severe corrosion of cell components and low anodic stability. Herein, we report for the first time, a chloride-free Mg(HMDS)₂-based electrolyte in 1,2-dimethoxyethane. By chem. controlling the moisture content using tetrabutylammonium borohydride as a moisture scavenger, the electrolyte demonstrates outstanding electrochem. performance in magnesium plating/stripping, with an average Coulombic efficiency of 98.3% over 150 cycles, and is noncorrosive to cell components. Surface anal. and depth profiling of the magnesium metal anode reveals the formation of a robust solid electrolyte interphase at the anode-electrolyte nanointerface, which allows magnesium plating/stripping to occur reversibly. The electrolyte also demonstrates good compatibility with a copper sulfide nanomaterial cathode, which exhibits a high initial discharge capacity of 261.5 mAh g^-1. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2COA of Formula: C8H18O4).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.COA of Formula: C8H18O4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Finely dispersed AgPd bimetallic nanoparticles on a polydopamine modified metal organic framework for diverse catalytic applications was written by Mishra, Biswajit;Ghosh, Dibyajyoti;Tripathi, Bijay P.. And the article was included in Journal of Catalysis in 2022.Application of 105-13-5 This article mentions the following:

An efficiently supported noble metal-based heterogeneous catalyst with ultrafine dispersion and small size for multifunctional catalysis and pollutant degradation is highly desirable. In this work, a polydopamine modified-MOF (MIL-125-NH₂) template has been used to synthesize ultrafine silver-palladium (AgPd) bimetallic nanoparticles. The characterization results confirm the formation of well-dispersed ultrafine bimetallic nanoparticles with a narrow size distribution (2.2 ± 0.3 nm). The prepared catalyst exhibits excellent heterogeneous catalytic activity with high turnover frequency in batch and continuous nitrophenol reduction, aldehyde hydrogenation, formic acid dehydrogenation (in the presence of additive sodium formate), and Suzuki-Miyaura coupling reaction at ambient conditions. Moreover, its high stability makes it a durable catalyst system for multicycle use after recycling or in a continuous flow reactor. The rate of hydrogen production using AgPd@MIL-125-NH₂-PDA is many orders of magnitude higher than that of uncoated and monometallic (Ag or Pd) nanoparticles on MOF. Addnl., d. functional theory (DFT) calculations provide an insight mechanism for each FA dehydrogenation step and show that the bimetallic nanoparticle on PDA coated MOF has better selectivity towards FA dehydrogenation by following a lower energy path for hydrogen desorption. These findings highlight the advantages of rational template modification in synthesizing finer bimetallic nanoparticles, which can open up many new avenues for designing metal nanoparticle-MOF-based composite materials for a variety of potential applications. In the experiment, the researchers used many compounds, for example, (4-Methoxyphenyl)methanol (cas: 105-13-5Application of 105-13-5).

(4-Methoxyphenyl)methanol (cas: 105-13-5) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Application of 105-13-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Design of polymer network and Li+ solvation enables thermally and oxidatively stable, mechanically reliable, and highly conductive polymer gel electrolyte for lithium batteries was written by Hashimoto, Kei;Tatara, Ryoichi;Ueno, Kazuhide;Dokko, Kaoru;Watanabe, Masayoshi. And the article was included in Journal of the Electrochemical Society in 2021.Computed Properties of C8H18O4 This article mentions the following:

Herein, we demonstrate that design of polymer network and Li+-ion solvation enables the fabrication of thermally and oxidatively stable, mech. reliable, and highly conductive polymer gel electrolytes for lithium batteries. Polymer gel electrolytes have been used for Li-ion batteries (LIB) due to their quasi-solid natures and flexible shapes. However, they frequently suffer from the high vapor pressures of the incorporated solvents, low oxidative stabilities, and poor mech. properties. To overcome these drawbacks, we fabricated a tough gel electrolyte comprising a tetra-arm poly(ethylene glycol) (TPEG) homogeneous polymer network, in which a tetraglyme(G4)-based solvate ionic liquid (SIL) was incorporated. It was intriguing to find that the solvation of Li+ ion by oxygen atoms (within G4 and TPEG), represented as [O]/[Li], governed the thermal and oxidative stabilities of the gel electrolyte, while the homogeneous network contributed to the mech. reliability and high ionic conductivity At [O]/[Li] = 5, the TPEG-based gel electrolyte with no free solvent simultaneously exhibited high thermal (>200°C) and oxidative stabilities (>4.4 V), high stretchability, and high ionic conductivity (~1 mS cm-1 at 30°C). These favorable properties of the gel electrolyte resulted in reversible charge/discharge of a 4-V-class high-voltage cathode (LiNi0.6Mn0.2Co0.2O2, NMC622). In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2Computed Properties of C8H18O4).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Computed Properties of C8H18O4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis of Allenes from Allylic Alcohol Derivatives Bearing a Bromine Atom Using a Palladium(0)/Diethylzinc System was written by Ohno, Hiroaki;Miyamura, Kumiko;Tanaka, Tetsuaki;Oishi, Shinya;Toda, Ayako;Takemoto, Yoshiji;Fujii, Nobutaka;Ibuka, Toshiro. And the article was included in Journal of Organic Chemistry in 2002.Recommanded Product: 3929-47-3 This article mentions the following:

A general and efficient synthesis of allenes using a palladium(0)/diethylzinc system is described. Treatment of mesylates or trichloroacetates of (E)- or (Z)-2-bromoalk-2-en-1-ols with diethylzinc in the presence of a catalytic amount of palladium(0) affords allenes bearing an aminoalkyl, alkyl, or aryl substituent(s) in good to high yields. No transfer of chirality from the stereogenic center carrying the mesyloxy group to the allene was observed In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Recommanded Product: 3929-47-3).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Recommanded Product: 3929-47-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Robust Strategy of Quasi-Solid-State Electrolytes to Boost the Stability and Compatibility of Mg Ion Batteries was written by Sun, Jianchao;Zou, Yabing;Gao, Shizhe;Shao, Lianyi;Chen, Chengcheng. And the article was included in ACS Applied Materials & Interfaces in 2020.Reference of 112-49-2 This article mentions the following:

Magnesium ion batteries (MIBs) have attracted a lot of attention because of the natural abundance of magnesium, high volumetric energy d., and superior safety. Nevertheless, MIBs are still in their infancy because of the significant challenge in developing a suitable electrolyte with low flammability, high ionic conductivity, and compatibility with the Mg anode. Herein, we construct rechargeable quasi-solid-state MIBs based on tailored polymer electrolytes. The quasi-solid state electrolyte of poly(vinylidene fluoride-co-hexafluoropropylene)-nanosized SiO₂-Mg(TFSI)₂ combines the outstanding dynamic property of a liquid electrolyte and the good stability of a solid-state electrolyte. It exhibits a highly reversible Mg²⁺ deposition-dissolution capability, high ion conductivity (0.83 mS cm^-1), and superior compatibility with the Mg metal and cathode. The quasi-solid-state MIBs with a layered titanic oxide cathode show a high reversible capacity of 129 mA h g^-1 at 50 mA g^-1 (150 W h kg^-1) without any decay after 100 cycles. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2Reference of 112-49-2).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Reference of 112-49-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Carbon-carbon main chain polymer with accumulated oligo(ethylene glycol)-substituted cyclotriphosphazenes: Study on the LCST-type phase separation of organic-inorganic poly(substituted methylene)s was written by Shimomoto, Hiroaki;Yamada, Tomohiro;Itoh, Tomomichi;Ihara, Eiji. And the article was included in Polymer Journal (Tokyo, Japan) in 2020.Electric Literature of C5H12O3 This article mentions the following:

The synthesis and characterization of organic-inorganic thermoresponsive poly(substituted methylene)s are described. Diazoacetates with oligo(ethylene glycol)-substituted cyclotriphosphazenes were synthesized, and the obtained products were employed as monomers for Pd-initiated polymerization to produce carbon-carbon main chain polymers bearing an oligo(ethylene glycol)-substituted cyclotriphosphazene on every main chain carbon atom. The resulting polymers with densely accumulated oligo(ethylene glycol) units around the polymer main chain showed lower critical solution temperature-type phase separation in an aqueous medium. In the experiment, the researchers used many compounds, for example, 2-(2-Methoxyethoxy)ethanol (cas: 111-77-3Electric Literature of C5H12O3).

2-(2-Methoxyethoxy)ethanol (cas: 111-77-3) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Electric Literature of C5H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Metal-Free Twofold Electrochemical C-H Amination of Activated Arenes: Application to Medicinally Relevant Precursor Synthesis was written by Wesenberg, Lars J.;Diehl, Erika;Zaehringer, Till J. B.;Doerr, Carolin;Schollmeyer, Dieter;Shimizu, Akihiro;Yoshida, Jun-ichi;Hellmich, Ute A.;Waldvogel, Siegfried R.. And the article was included in Chemistry – A European Journal in 2020.Safety of 2-(4-Methoxyphenoxy)acetic acid This article mentions the following:

The efficient production of many medicinally or synthetically important starting materials suffers from wasteful or toxic precursors for the synthesis. In particular, the aromatic non-protected primary amine function represents a versatile synthetic precursor, but its synthesis typically requires toxic oxidizing agents and transition metal catalysts. The two fold electrochem. amination of activated benzene derivatives 3-R-4-R¹-5-R²-C₆H₂OC(R³)(R⁴)C(O)R⁵ [R = H, OMe; R¹ = H, OMe; R² = H, OMe; R¹R² = -CH=C(OCH₃)-CH=CH-; R³ = H, Me, Ph, 2-chlorophenyl; R⁴ = H, Me; R⁵ = methyloxidanyl, Ph] and 2,2-bis[4-(methoxycarbonylmethoxy)phenyl]propane via Zincke intermediates provides an alternative sustainable strategy for the formation of new C-N bonds of high synthetic value. This approach is used to generate benzoxazinone scaffolds I (R⁶ = F, Br, Me) that gained attention as a starting structure against castrate-resistant prostate cancer. Further improvement of the structure led to significantly increased cancer cell line toxicity. Thus, exploiting environmentally benign electrooxidation, a new versatile and powerful method based on direct C-H activation that is applicable for example the production of medicinally relevant compounds was presented. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Safety of 2-(4-Methoxyphenoxy)acetic acid).

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Safety of 2-(4-Methoxyphenoxy)acetic acid

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem