Khan, Khalid Mohammed et al. published their research in Journal of the Chemical Society of Pakistan in 2013 | CAS: 57179-35-8

3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Reference of 57179-35-8

Antibacterial activities of some arylidene barbiturate derivatives was written by Khan, Khalid Mohammed;Ali, Muhammad;Ahmad, Aqeel;Amyn, Afroze;Karim, Aneela;Khan, Momin;Parveen, Shahnaz. And the article was included in Journal of the Chemical Society of Pakistan in 2013.Reference of 57179-35-8 This article mentions the following:

A series of arylidene barbiturates 1-18 has been synthesized and evaluated against a number of Gram-pos. and Gram-neg. bacterial strains. Chromenopyrimidinedione derivatives 16 and 18 were found to be the most active against a number of Gram-pos. organisms while compound 13 also showed antimicrobial activity against four Gram-pos. strains. No significant activity was observed against Gram-neg. bacterial strains. In the experiment, the researchers used many compounds, for example, 3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8Reference of 57179-35-8).

3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Reference of 57179-35-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Jiang, Li et al. published their research in Huaxue Xuebao in 1995 | CAS: 1877-75-4

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Formula: C9H10O4

Studies on mixed trialkyltin derivatives. VIII. Synthesis, characterization and biological activities of methyldicyclohexyltin aryloxyacetates was written by Jiang, Li;Yang, Zhi-Qiang;Xie, Qing-Lan;Shan, Shu-Xiang. And the article was included in Huaxue Xuebao in 1995.Formula: C9H10O4 This article mentions the following:

The synthesis of twenty XnC6H5-nOCH2CO2SnCy2Me (Cy = cyclohexyl; n = 1, X = H, 2-, 3-, and 4-Cl, 2- and 4-Br, 2-, 3-, and 4-Me, 2- and 4-MeO, 4-iodo, 3-NO2; n = 2, X2 = 2,3-, 2,4-, 2,6-, 3,4-, and 3,5-Me2, 2-MeO-4-allyl; n = 3, X3 = 2,4,5-Cl3) in 90-95% yields from bis(methyldicyclohexyltin) oxide and the corresponding aryloxyacetic acids is reported. Their characterization by IR and NMR (1H, 13C, 119Sn) spectroscopy is described. These compounds are five-coordinate, carboxylate-bridged polymers except 11 and 12. A good linear relation is found between the 119Sn chem. shifts and the aryl groups: δ119Sn = 6.23σ + 94.67, r = 0.943. The results of the preliminary bioassay showed that the compounds have better antibiotic activities to plant pathogenic fungi, herbicidal and inhibitory activities, especially high acaricidal activity. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Formula: C9H10O4).

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Formula: C9H10O4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Szollosi, Gyoergy et al. published their research in Advanced Synthesis & Catalysis in 2013 | CAS: 5367-32-8

3-Methyl-4-nitroanisole (cas: 5367-32-8) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Name: 3-Methyl-4-nitroanisole

Preparation of Optically Enriched 3-Hydroxy-3,4-dihydroquinolin-2(1H)-ones by Heterogeneous Catalytic Cascade Reaction over Supported Platinum Catalyst was written by Szollosi, Gyoergy;Makra, Zsolt;Kovacs, Lenke;Fueloep, Ferenc;Bartok, Mihaly. And the article was included in Advanced Synthesis & Catalysis in 2013.Name: 3-Methyl-4-nitroanisole This article mentions the following:

The development of a novel heterogeneous catalytic asym. cascade reaction for the synthesis of tetrahydroquinolines from 2-nitrophenylpyruvatesis reported. Optically enriched 3-hydroxy-3,4-dihydroquinolin-2(1H)-ones I (R = Et, Me, X = H, 3-Me, 4-Me, 5-Me, 6-Me, 3-MeO, 5-MeO, 3-iso-Pr, 4-F, 5-F, 6-F, Y = H, 5-Me) are prepared from pyruvates II by enantioselective hydrogenation of the activated keto group over a Cinchona alkaloid-modified Pt catalyst, reduction of the nitro group and spontaneous cyclization cascade. Acceleration of the enantioselective hydrogenation of the activated keto group over the catalyst modified by Cinchona alkaloids ensured high tetrahydroquinolinone selectivities. The scope of the reaction was checked using twelve substrates. Both yields and enantioselectivities were significantly influenced by the nature and position of the substituents on the Ph ring. Substituents adjacent to the nitro group considerably increased the product yield, due to their effect on the nitro group’s reduction rate; however, had only a limited effect on enantioselectivities. In the experiment, the researchers used many compounds, for example, 3-Methyl-4-nitroanisole (cas: 5367-32-8Name: 3-Methyl-4-nitroanisole).

3-Methyl-4-nitroanisole (cas: 5367-32-8) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Name: 3-Methyl-4-nitroanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

van Vuuren, Estefan et al. published their research in Organometallics in 2022 | CAS: 16356-02-8

1,4-Dimethoxy-2-butyne (cas: 16356-02-8) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).HPLC of Formula: 16356-02-8

Self-Isomerized-Cyclometalated Rhodium NHC Complexes as Active Catalysts in the Hydrosilylation of Internal Alkynes was written by van Vuuren, Estefan;Malan, Frederick P.;Cordier, Werner;Nell, Margo;Landman, Marile. And the article was included in Organometallics in 2022.HPLC of Formula: 16356-02-8 This article mentions the following:

A range of unique Rh-based bidentate NHC complexes that are formed in a base free-tandem isomerization/cyclometalation process, were synthesized (1–4) from a range of imidazolium salts with an N-alkenyl tether. Cyclometalation occurred with complex 1 leading to an unprecedented complex, which is the 1st and only example in literature of a nonaromatic C(sp2)-H activation leading to a C(sp3)-Rh cyclometalated product with a concomitant intramol./isomerization process. Dealkylation of the N-alkenyl substituent occurred to form byproducts that showed metal N-coordination (1b and 2b). These byproducts, 1b and 2b, were further reacted with the anion exchange reagent NH4PF6 to form the dimeric complexes 1bd and 2bd. All the complexes were applied as precatalysts in the hydrosilylation of internal alkynes with excellent performance (conversions of 66-100%) after only 1 h at 80° without the use of an additive. Anticancer studies showed that complexes presented with half-maximal inhibitory concentrations ranging from 3.71 to 25.85μM. Depending on the cell line, complex 4 was the most cytotoxic complex, especially in the BT-20 triple-neg. breast carcinoma, MCF-12A nontumorigenic mammary gland cell, MDA-MB-231 triple-neg. breast carcinoma and MCF-7/TAMR-1 tamoxifen-resistant subtype of the MCF-7 estrogen- and progesterone-pos. luminal breast carcinoma cell lines. In the experiment, the researchers used many compounds, for example, 1,4-Dimethoxy-2-butyne (cas: 16356-02-8HPLC of Formula: 16356-02-8).

1,4-Dimethoxy-2-butyne (cas: 16356-02-8) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).HPLC of Formula: 16356-02-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Demetriou, Anna M. et al. published their research in Journal of Materials Chemistry in 2008 | CAS: 66943-05-3

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Recommanded Product: 66943-05-3

Using high-throughput techniques to identify complexants for 137Cs, 60Co and 90Sr was written by Demetriou, Anna M.;Crouch, David J.;Batey, Helen D.;Faulkner, Stephen;Yeates, Stephen G.;Livens, Francis R.. And the article was included in Journal of Materials Chemistry in 2008.Recommanded Product: 66943-05-3 This article mentions the following:

High-throughput synthetic and screening methods have been used to prepare and evaluate Cs, Co and Sr selective sequestering agents derived from aza-crown ethers. Storage phosphor autoradiog. was the screening method used to determine potential lead compounds The most effective complexants for Cs+ have a very high selectivity over K ions and will bind picomolar quantities of Cs+ in the presence of mM K+. The binding and selectivity of these compounds with 60Co and 90Sr have also been studied and selectivity was also determined with tap H2O and Ca2+, resp. Experiments with tap H2O spiked with 137Cs and 60Co were carried out to confirm the decontamination capabilities of some of the compounds and a good correlation between autoradiog. and these results were found. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3Recommanded Product: 66943-05-3).

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Recommanded Product: 66943-05-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Destrade, C. et al. published their research in Molecular Crystals and Liquid Crystals in 1976 | CAS: 39969-26-1

1-Methoxy-4-((4-propylphenyl)ethynyl)benzene (cas: 39969-26-1) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Computed Properties of C18H18O

Application of Raman diffusion to the determination of alkyl chain order in two homologous series of nematogenic compounds was written by Destrade, C.;Guillon, F.;Gasparoux, H.. And the article was included in Molecular Crystals and Liquid Crystals in 1976.Computed Properties of C18H18O This article mentions the following:

The Raman spectra of the homologous series p-methoxy-p’-alkyltolanes (I) and p-methoxybenzilidene-p’-alkylanilines (II; R = C1-C5 alkyl) are determined in isotropic, nematic, and solid phases. The resonance lines of cis and trans bonds were located at âˆ?00 cm-1. From the relative intensity of these lines vs. temperature, one could define a parameter (f), useful in the understanding of the ordering within the alkyl chain. Pretransitional effects, at the I â†?N transition, were observed, and established the existence of intramol. chain ordering in the isotropic phase even far from the transition point. This ordering did not exist in the case of nonnematogenic compounds From f was calculated the value of the order parameter S3. In the experiment, the researchers used many compounds, for example, 1-Methoxy-4-((4-propylphenyl)ethynyl)benzene (cas: 39969-26-1Computed Properties of C18H18O).

1-Methoxy-4-((4-propylphenyl)ethynyl)benzene (cas: 39969-26-1) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Computed Properties of C18H18O

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Liang, Jian-Hua et al. published their research in European Journal of Medicinal Chemistry in 2012 | CAS: 1132-95-2

1,1-Diisopropoxycyclohexane (cas: 1132-95-2) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Category: ethers-buliding-blocks

Structure-activity relationships of novel alkylides: 3-O-Arylalkyl clarithromycin derivatives with improved antibacterial activities was written by Liang, Jian-Hua;Li, Xiao-Li;Wang, He;An, Kun;Wang, Yue-Ying;Xu, Ying-Chun;Yao, Guo-Wei. And the article was included in European Journal of Medicinal Chemistry in 2012.Category: ethers-buliding-blocks This article mentions the following:

A series of novel alkylides, possessing 3-O-arylalkyl group instead of 3-O-cladinose, were designed, synthesized and evaluated for in vitro antibacterial activities. The increased potency clearly ranked by the order of 3-O-(3-aryl-2-propargyl), 3-O-(3-aryl-E-prop-2-enyl), 3-O-(3-aryl-propyl), and 3-O-(3-aryl-Z-prop-1-enyl) groups. Some alkylides, e.g. I, showed improved activities against inducible MLSB resistance and efflux resistance compared to the second-generation macrolides. Among them, I possessed comparable activities against erythromycin-susceptible Staphylococcus aureus, Streptococcus pneumoniae and Streptococcus pyogenes (MICs of 0.016-0.5 μg/mL). Moreover, I displayed dramatically enhanced potency against both efflux resistant and MLSB resistant strains (MICs of 0.125-0.5 μg/mL) resistant to clarithromycin and azithromycin (MICs of 1- >254 μg/mL), independent of methicillin-susceptible and methicillin-resistant pheno-types. In the experiment, the researchers used many compounds, for example, 1,1-Diisopropoxycyclohexane (cas: 1132-95-2Category: ethers-buliding-blocks).

1,1-Diisopropoxycyclohexane (cas: 1132-95-2) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Jozwiak, Malgorzata et al. published their research in Journal of Molecular Liquids in 2020 | CAS: 112-49-2

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Recommanded Product: 112-49-2

Solvation enthalpy of selected glymes in the mixtures of N,N-dimethylformamide with propan-1-ol or methanol at 298.15 K. The solvent contribution to the solvation enthalpy of glymes was written by Jozwiak, Malgorzata;Ludzik, Katarzyna;Cokot, Maria;Jozwiak, Andrzej;Klys, Arkadiusz. And the article was included in Journal of Molecular Liquids in 2020.Recommanded Product: 112-49-2 This article mentions the following:

The enthalpies of solution of monoglyme, diglyme, triglyme, tetraglyme, pentaglyme and hexaglyme in N,N-dimethylforamide+propan-1-ol mixtures have been measured at 298.15 K. The preferential solvation process of glymes mols. in the mixtures of N,N-dimethylformamide with methanol or propan-1-ol has been discussed. Then the contribution of DMF, PrOH, and MeOH to the solvation enthalpy of group (-CH2- and -O-) of glymes has been calculated On the basis of the obtained data, the effect of the structural and energetic properties of the N,N-dimethylforamide+propan-1-ol mixtures on the solution enthalpy of glymes in this mixtures has been analyzed. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2Recommanded Product: 112-49-2).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Recommanded Product: 112-49-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Fujihira, Yamato et al. published their research in Bulletin of the Chemical Society of Japan in 2022 | CAS: 112-49-2

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Reference of 112-49-2

Continuous-Flow Synthesis of Perfluoroalkyl Ketones via Perfluoroalkylation of Esters Using HFC-23 and HFC-125 under a KHMDS-Triglyme System was written by Fujihira, Yamato;Iwasaki, Hiroto;Sumii, Yuji;Adachi, Hiroaki;Kagawa, Takumi;Shibata, Norio. And the article was included in Bulletin of the Chemical Society of Japan in 2022.Reference of 112-49-2 This article mentions the following:

Herein, a method for the chem. transformation of two HFCs, viz was described. HFC-23 and HFC-125, based on the continuous-flow perfluoroalkylation of esters to synthesize the pharmaceutically and agrochem. vital trifluoromethyl and pentafluoroethyl ketones. The combination of a potassium base and a glyme solvent system was found to be the most effective. The proposed method was attractive for industrial use because it allows the consumption of a large volume of HFCs, promotes the synthesis of high-value medicinal compounds, and serves as an ideal alternative to the current HFC decomposition processes like thermal plasma treatment. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2Reference of 112-49-2).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Reference of 112-49-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ozcan, Elif et al. published their research in ChemistrySelect in 2021 | CAS: 111-77-3

2-(2-Methoxyethoxy)ethanol (cas: 111-77-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Synthetic Route of C5H12O3

Effect of the Hydrophilic/Hydrophobic Pendants on Physicochemical Properties: Applications Based on Cyclotriphosphazene Core was written by Ozcan, Elif;Uslu, Aylin. And the article was included in ChemistrySelect in 2021.Synthetic Route of C5H12O3 This article mentions the following:

This study focused on investigating the effect of hydrophilic and hydrophobic substituents on the physicochem. properties for medical applications. In this study, to understand the effect of hydrophilic and hydrophobic substituents on physicochem. parameters such as lipophilicity and thermosensitivity, a series of cis-tris nongeminal [N3P3(R1-4)3(Ra-f)3] cyclotriphosphazenes [R1-4=diethylene glycol monomethyl ether (DEGME), triethylene glycol monomethyl ether (TEGME), methoxypolyethylene glycol (mPEG350), methoxypolyethylene glycol-550 (mPEG550); (2-5) resp.; Ra-f=pyrazole, 3,5-dimethylpyrazole, imidazole, 2-Me imidazole, benzimidazole, 5,6-di-Me benzimidazole, [2(a-f), 3(a-f), 4(a-f), 5(a-f)] resp.] were synthesized and fully characterized by mass, 31P and 1H NMR spectroscopies. Solubility and thermosensitivity based on substituent dependent LCST (lower critical solution temperature) behavior of all synthesized mols. are investigated. Each compound analyzed by HPLC to determine the lipophilicity values (logPo/w) between n-octanol and water. A good correlation (r = 0.9975 and R2 = 0.9948) was observed between the exptl. determined logPo/w and estimated milogP values. The results showed that LCST values of the reported compounds were linearly correlated with their lipophilicity values. In the experiment, the researchers used many compounds, for example, 2-(2-Methoxyethoxy)ethanol (cas: 111-77-3Synthetic Route of C5H12O3).

2-(2-Methoxyethoxy)ethanol (cas: 111-77-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Synthetic Route of C5H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem