Ding, Wei et al. published their research in Chemical Science in 2020 |CAS: 321-28-8

The Article related to arylbenziodoxole site selective preparation, arene benziodoxole triflate site selective aromatic iodanation, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Recommanded Product: 321-28-8

Ding, Wei; Wang, Chen; Tan, Jie Ren; Ho, Chang Chin; Leon, Felix; Garcia, Felipe; Yoshikai, Naohiko published an article in 2020, the title of the article was Site-selective aromatic C-H λ3-iodanation with a cyclic iodine(III) electrophile in solution and solid phases.Recommanded Product: 321-28-8 And the article contains the following content:

An efficient and site-selective aromatic C-H λ3-iodanation reaction was achieved using benziodoxole triflate (BXT) as an electrophile under room temperature conditions. The reaction tolerated a variety of electron-rich arenes and heteroarenes to afford the corresponding arylbenziodoxoles I [R = 4-OMeC6H4, 2,4-di-MeC6H3, 2-thienyl, etc.] in moderate to good yields. The reaction could also be performed mechanochem. by grinding a mixture of solid arenes and BXT under solvent-free conditions. The arylbenziodoxoles could be used for various C-C and C-heteroatom bond formations and are also amenable to further modification by electrophilic halogenation. DFT calculations suggested that the present reaction proceeded via a concerted λ3-iodanation-deprotonation transition state, where the triflate anion acts as an internal base. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Recommanded Product: 321-28-8

The Article related to arylbenziodoxole site selective preparation, arene benziodoxole triflate site selective aromatic iodanation, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Recommanded Product: 321-28-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Jovene, Cyril et al. published their research in European Journal of Organic Chemistry in 2016 |CAS: 321-28-8

The Article related to benzofuroxan preparation sulfonate substitution heterocyclization, benzofurazan preparation deoxygenation, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Name: 1-Fluoro-2-methoxybenzene

Jovene, Cyril; Marrot, Jerome; Jasmin, Jean-Philippe; Chugunova, Elena; Goumont, Regis published an article in 2016, the title of the article was A Synthetic Pathway to Substituted Benzofuroxans through the Intermediacy of Sulfonates: The Case Example of Fluoro-Nitrobenzofuroxans.Name: 1-Fluoro-2-methoxybenzene And the article contains the following content:

Benzofuroxans are well known compounds that continue to attract particular attention since the discovery of 4,6-dinitrobenzofuroxan (DNBF) back in 1899. It has been shown that these compounds possess biol. activities that are related to their electronic behaviors and the positioning of substituents borne by the heterocycles. In this paper, we report the first synthesis of 4-fluoro-6-nitrobenzofuroxan and 6-fluoro-4-nitrobenzofuroxan; the altered positions of the substituents enabling us to carry out structural and reactivity comparisons, with DNBF and 4,6-difluorobenzofuroxan. These compounds have been unambiguously characterized through NMR and radiocrystallog. studies. Two main synthetic pathways involving fluoroanisoles and fluorophenols, cheap and easily available chems., have been successfully developed. Finally, benzofurazan analogs have been prepared via deoxygenation of corresponding benzofuroxans with tri-Et phosphite. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Name: 1-Fluoro-2-methoxybenzene

The Article related to benzofuroxan preparation sulfonate substitution heterocyclization, benzofurazan preparation deoxygenation, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Name: 1-Fluoro-2-methoxybenzene

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Shibasaki, Kaho et al. published their research in Heterocycles in 2020 |CAS: 578-58-5

The Article related to alkyl aryltetrazole preparation, arene acyl chloride friedel crafts acylation beckmann rearrangement, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Synthetic Route of 578-58-5

Shibasaki, Kaho; Togo, Hideo published an article in 2020, the title of the article was Facile preparation of 5-alkyl-1-aryltetrazoles with arenes, acyl chlorides, hydroxylamine, and diphenylphosphoryl azide.Synthetic Route of 578-58-5 And the article contains the following content:

Successive treatment of arenes with acyl chlorides and AlCl3, the addition of water and removal of solvent, the reaction with NH2OH·HCl and K2CO3, and the reaction with diphenylphosphoryl azide and DBU under warming conditions gave the corresponding 5-alkyl-1-aryltetrazoles efficiently in good to moderate yields. The present method is one-pot transformation of arenes into 5-alkyl-1-aryltetrazoles I (R = Me, iPr, Ph, etc.; R1 = 4-tBuC6H4, 4-MeOC6H4, 4-ClC6H4, etc.) using the Friedel-Crafts acylation and the Beckmann rearrangement under transition-metal-free conditions. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Synthetic Route of 578-58-5

The Article related to alkyl aryltetrazole preparation, arene acyl chloride friedel crafts acylation beckmann rearrangement, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Synthetic Route of 578-58-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Chen, Li et al. published their patent in 2010 |CAS: 1162054-86-5

The Article related to thiadiazole arylamide preparation p2x3 p2x2 antagonist pain urinary disease, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Application In Synthesis of (S)-1-Methoxypropan-2-amine hydrochloride

On June 17, 2010, Chen, Li; Feng, Lichun; Yang, Minmin; Dillon, Michael Patrick; Lai, Yingjie published a patent.Application In Synthesis of (S)-1-Methoxypropan-2-amine hydrochloride The title of the patent was Preparation of thiadiazole-substituted arylamides as P2X3 and P2X2/3 antagonists for treatment of pain and urinary tract disease. And the patent contained the following:

Compounds of the formula I (wherein R1 is (un)substituted thiadiazolyl; R2 is (un)substituted Ph, (un)substituted pyridinyl, (un)substituted pyrimidinyl, etc.; R3 is H, C1-6alkyl, or CN; R4 is H or C1-6alkyl; or R3 and R4 together with the atom to which they are attached may form a C3-6 carbocyclic ring; R5 is C1-6alkyl, C1-6alkoxy-C1-6alkyl, hydroxy-C1-6alkyl, etc.; or R4 and R5 together form part of a ring; or R3, R4, and R5 together form part of ring; R6, R7 and R8 are independently H, C1-6alkyl, C1-6alkyloxy, etc.) or a pharmaceutically acceptable salt thereof, are disclosed. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptors and methods of making the compounds Example compound II, prepared in a multistep reaction that culminated in the reaction of 3-(4-isopropyl-[1,2,3]thiadiazol-5-yl)-5-(5-methylpyridin-2-yl)benzoic acid and C-(5-methylpyrazin-2-yl)methylamine, had pKi values of 8.04 and 7.43 for P2X3 and P2X2/3 receptors, resp. The experimental process involved the reaction of (S)-1-Methoxypropan-2-amine hydrochloride(cas: 1162054-86-5).Application In Synthesis of (S)-1-Methoxypropan-2-amine hydrochloride

The Article related to thiadiazole arylamide preparation p2x3 p2x2 antagonist pain urinary disease, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Application In Synthesis of (S)-1-Methoxypropan-2-amine hydrochloride

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Dong, Chenlu et al. published their research in Journal of Organic Chemistry in 2021 |CAS: 578-58-5

The Article related to substituted furoxan preparation regioselective, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Application of 578-58-5

On November 5, 2021, Dong, Chenlu; Zhao, Xufeng; Katsuragi, Yuki; Kim, Hojin; Hayashi, Masahiko; Matsubara, Ryosuke published an article.Application of 578-58-5 The title of the article was Furoxan Incorporation into C-H Bonds Enabling Nitrogen-Containing Functional Group Installation into the Same. And the article contained the following:

A C-C bond forming method was developed, whereby a furoxan ring was incorporated into various types of C-H bonds. The protocol not only offered a concise synthetic route to a variety of substituted furoxan derivatives I [R = Bn, C(O)NH2, tetrahydrofuran-2-yl, etc.; R1 = OEt, SO2Ph] but also provided an efficient strategy for the insertion of various nitrogen-containing functional groups into C-H bonds via transformation of the resultant furoxan ring. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Application of 578-58-5

The Article related to substituted furoxan preparation regioselective, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Application of 578-58-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Pan, Yue et al. published their research in Organic Letters in 2022 |CAS: 93-04-9

The Article related to amidyl iminophenylacetic acid hetero arene ruthenium catalyst photochem sulfonamidation, hetero aryl benzene sulfonamide preparation chemoselective regioselective, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Category: ethers-buliding-blocks

On September 16, 2022, Pan, Yue; Liu, Zhengyi; Zou, Peng; Chen, Yali; Chen, Yiyun published an article.Category: ethers-buliding-blocks The title of the article was Hypervalent Iodine Reagents Enable C(sp2)-H Amidation of (Hetero)arenes with Iminophenylacetic Acids. And the article contained the following:

The sulfonamidyl (hetero)arenes synthesis by the C(sp2)-H amidation from bench-stable amidyl-iminophenylacetic acids was reported. The hypervalent iodine reagents covalently activated iminophenylacetic acids for the facile sulfonamidyl radical generation under mild photocatalytic oxidative conditions. Diversified indoles, pyrroles, imidazopyridines and fused arenes underwent the C(sp2)-H amidation with excellent chemoselectivity and regioselectivity. This reaction performed well under neutral aqueous conditions with potential biol. applications. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Category: ethers-buliding-blocks

The Article related to amidyl iminophenylacetic acid hetero arene ruthenium catalyst photochem sulfonamidation, hetero aryl benzene sulfonamide preparation chemoselective regioselective, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Jacob, Nicolas et al. published their research in Journal of the American Chemical Society in 2022 |CAS: 93-04-9

The Article related to methoxyphenyl indole methanimine chloronaphthalene cobalt catalyst enantioselective arylation, naphthalenyl indole carbaldehyde preparation, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Recommanded Product: 93-04-9

On January 19, 2022, Jacob, Nicolas; Zaid, Yassir; Oliveira, Joao C. A.; Ackermann, Lutz; Wencel-Delord, Joanna published an article.Recommanded Product: 93-04-9 The title of the article was Cobalt-Catalyzed Enantioselective C-H Arylation of Indoles. And the article contained the following:

Herein, the unprecedented earth-abundant 3D-metal-catalyzed atroposelective direct arylation was reported, furnishing rare atropoisomeric C2-arylated indoles. Kinetic studies and DFT computation revealed an uncommon mechanism for this asym. transformation, with the oxidative addition being the rate- and enantio-determining step. Excellent stereoselectivities were reached (up to 96% ee), while using an unusual N-heterocyclic carbene-ligand bearing essential remote substituent. Attractive dispersion interactions along with pos. C-H—π interactions exerted by the ligand were identified as key factors to guarante the excellent enantioselection. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Recommanded Product: 93-04-9

The Article related to methoxyphenyl indole methanimine chloronaphthalene cobalt catalyst enantioselective arylation, naphthalenyl indole carbaldehyde preparation, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Recommanded Product: 93-04-9

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Kasama, Kengo et al. published their research in RSC Advances in 2021 |CAS: 93-04-9

The Article related to hydroxynaphthalenyl carbazole preparation regioselective chemoselective, hydroxycarbazole naphthol coupling reaction oxovanadium catalyst, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Safety of 2-Methoxynaphthalene

Kasama, Kengo; Kanomata, Kyohei; Hinami, Yuya; Mizuno, Karin; Uetake, Yuta; Amaya, Toru; Sako, Makoto; Takizawa, Shinobu; Sasai, Hiroaki; Akai, Shuji published an article in 2021, the title of the article was Chemo- and regioselective cross-dehydrogenative coupling reaction of 3-hydroxycarbazoles with arenols catalyzed by a mesoporous silica-supported oxovanadium.Safety of 2-Methoxynaphthalene And the article contains the following content:

Cross-dehydrogenative coupling between 3-hydroxycarbazoles I(R = H; R1 = H, Br, Me; RR1 = -CH:CH-CH:CH-; R2 = H, Me, Ph, benzyl, acetyl, tolyl) and 2-naphthols II (R3 = 6-MeO, 7-Br, 3-Me, etc.) has been achieved by using a mesoporous silica-supported oxovanadium catalyst. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Safety of 2-Methoxynaphthalene

The Article related to hydroxynaphthalenyl carbazole preparation regioselective chemoselective, hydroxycarbazole naphthol coupling reaction oxovanadium catalyst, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Safety of 2-Methoxynaphthalene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Li, Laiqiang et al. published their research in Organic Letters in 2021 |CAS: 93-04-9

The Article related to carbonitrile indole green regioselective preparation, indole trimethylsilyl cyanide electrochem cyanation tris bromophenyl amine catalyst, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Recommanded Product: 2-Methoxynaphthalene

On August 6, 2021, Li, Laiqiang; Hou, Zhong-Wei; Li, Pinhua; Wang, Lei published an article.Recommanded Product: 2-Methoxynaphthalene The title of the article was Site-Selective Electrochemical C-H Cyanation of Indoles. And the article contained the following:

An electrochem. approach for the site-selective C-H cyanation of indoles to form indole-carbonitriles I [R1 = CN, Ph; R2 = Me, CN, C(O)OMe, etc.; R3 = H, 4-Me, 5-F, 6-Cl, etc.; R4 = Me, Bn, i-Pr, etc.] employing readily available TMSCN as cyano source has been developed. The electrosynthesis relied on the tris(4-bromophenyl)amine as a redox catalyst, which achieved better yield and regioselectivity. A variety of C2- and C3-cyanated indoles were obtained in satisfactory yields. The reactions were conducted in a simple undivided cell at room temperature and obviated the need for transition-metal reagent and chem. oxidant. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Recommanded Product: 2-Methoxynaphthalene

The Article related to carbonitrile indole green regioselective preparation, indole trimethylsilyl cyanide electrochem cyanation tris bromophenyl amine catalyst, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Recommanded Product: 2-Methoxynaphthalene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Sun, Xiao-Wen et al. published their research in Macromolecules (Washington, DC, United States) in 2021 |CAS: 150-78-7

The Article related to tripillararene based supramol polymer network preparation property, Physical Properties of Synthetic High Polymers: Analysis, Molecular Weight Determination, and Fractionation and other aspects.Formula: C8H10O2

On January 12, 2021, Sun, Xiao-Wen; Wang, Zhong-Hui; Li, Ying-Jie; Zhang, Yun-Fei; Zhang, You-Ming; Yao, Hong; Wei, Tai-Bao; Lin, Qi published an article.Formula: C8H10O2 The title of the article was Tri-pillar[5]arene-Based Multifunctional Stimuli-Responsive Supramolecular Polymer Network with Conductivity, Aggregation-Induced Emission, Thermochromism, Fluorescence Sensing, and Separation Properties. And the article contained the following:

Multifunctional stimuli-responsive supramol. polymers have applications in the field of smart materials. Herein, a tri-pillar[5]arene-based multifunctional stimuli-responsive supramol. polymer network gel (SPN-DTG) was successfully constructed. Interestingly, the SPN-DTG shows excellent conductivity and tunable blue aggregation-induced emission (AIE) properties. Meanwhile, a series of metal-ion-coordinated supramol. polymer network gels (MSPNs) were successfully constructed by rationally introducing various metal ions into SPN-DTG. The xerogel powder of SPN-DTG shows excellent separation capacity for the removal of Fe3+, Hg2+, Cu2+, and Co2+ from water. More importantly, the Co2+-coordinated supramol. polymer network gel MSPN-Co shows intriguing thermochromic properties. The color of MSPN-Co could be reversibly controlled between light yellow and dark green by controlling the system temperature In addition, the Fe3+-, Hg2+-, Cu2+-coordinated supramol. polymer network gel MSPNs (Mn+ = Fe3+, Hg2+, Cu2+) show high selectivity and quick fluorescence response for I- and H2PO4-. Therefore, the SPN-DTG has applications in multifunctional smart materials with conductivity, AIE, thermochromism, fluorescence detection, and separation properties. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Formula: C8H10O2

The Article related to tripillararene based supramol polymer network preparation property, Physical Properties of Synthetic High Polymers: Analysis, Molecular Weight Determination, and Fractionation and other aspects.Formula: C8H10O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem