Tag: 100-200

In 2019,RSC Advances included an article by Xue, Feng; Liu, Qibin; Zhu, Yong; Qing, Yunfei; Wan, Boshun. Recommanded Product: 10365-98-7. The article was titled 《Chiral benzene backbone-based sulfoxide-olefin ligands for highly enantioselective Rh-catalyzed addition of arylboronic acids to N-tosylarylimines》. The information in the text is summarized as follows:

An efficient Rh-catalyzed addition of arylboronic acids RB(OH)2 (R = Ph, 1-naphthyl, 4-BrC6H4, etc.) to N-tosylarylimines R1CH=NTs (R1 = Ph, 1-naphthyl, 4-BrC6H4, etc.) has been developed with chiral benzene backbone-based sulfoxide-olefin ligands, where 2-methoxy-1-naphthyl sulfinyl functionalized olefin ligands have shown to be more effective. The versatile method tolerates a wide range of functional groups and shows broad scope without regard to electronic or steric substitution pattern, allowing access to a broad range of chiral diarylmethylamines R1CH(R)NTs in high yields (up to 99%) with excellent enantioselectivities (up to 99% ee). After reading the article, we found that the author used 3-Methoxyphenylboronic acid(cas: 10365-98-7Recommanded Product: 10365-98-7)

3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.Recommanded Product: 10365-98-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,RSC Advances included an article by Wang, Tao; Guo, Jiarui; Wang, Xiaojuan; Guo, Han; Jia, Dingli; Wang, Hengjin; Liu, Lantao. Quality Control of 3-Methoxyphenylboronic acid. The article was titled 《Cross coupling of benzylammonium salts with boronic acids using a well-defined N-heterocyclic carbene-palladium(II) precatalyst》. The information in the text is summarized as follows:

N-heterocyclic carbene-palladium(II)-catalyzed cross-coupling of benzylammonium salts with arylboronic acids for the synthesis of diarylmethane derivatives via C-N bond activation were developed. Notably, in the presence of the easily prepared and bench-stable Pd-PEPPSI precatalyst, the Csp3-N bond activation of the benzylammonium salt even proceeded smoothly in isopropanol at room temperature The experimental part of the paper was very detailed, including the reaction process of 3-Methoxyphenylboronic acid(cas: 10365-98-7Quality Control of 3-Methoxyphenylboronic acid)

3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.Quality Control of 3-Methoxyphenylboronic acid

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,RSC Advances included an article by Sakai, Rika; Iguchi, Hiroki; Maruyama, Tatsuo. Formula: C8H8O3. The article was titled 《Quantification of azide groups on a material surface and a biomolecule using a clickable and cleavable fluorescent compound》. The information in the text is summarized as follows:

Here, we propose a novel method for quantifying azide groups on a solid surface and a protein using a clickable and cleavable fluorescent compound The clickable and cleavable fluorescent compound conjugates with the azide groups on the material surface and the fluorophore is then liberated into the solvent via a cleavage reaction, which can be simply quantified with a conventional fluorometer. In the experimental materials used by the author, we found 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Formula: C8H8O3)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.Formula: C8H8O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,ACS Omega included an article by Huang, Wenhua; Zhong, Chun-Hong. Computed Properties of C7H7BrO. The article was titled 《Metal-Free Synthesis of Aryltriphenylphosphonium Bromides by the Reaction of Triphenylphosphine with Aryl Bromides in Refluxing Phenol》. The information in the text is summarized as follows:

A metal-free synthesis of aryltriphenylphosphonium bromides by the reaction of triphenylphosphine with aryl bromides in refluxing phenol is developed. This reaction tolerates hydroxymethyl, hydroxyphenyl, and carboxyl groups in aryl bromides, allowing to synthesize multifunctional aryltriphenylphosphonium bromides, from which facile access to multifunctional aryldiphenylphosphines and their oxides by hydrolysis and subsequent reduction is exemplified. A two-step addition-elimination mechanism with the elimination step being a fast step is also proposed. After reading the article, we found that the author used 1-Bromo-3-methoxybenzene(cas: 2398-37-0Computed Properties of C7H7BrO)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Computed Properties of C7H7BrO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthetic Route of C8H8O3In 2021 ,《A ratiometric fluorescent probe for the rapid and specific detection of HSO3- in water samples》 appeared in Luminescence. The author of the article were Mu, Xinyue; Zhu, Jinbiao; Yan, Liqiang; Tang, Ningli. The article conveys some information:

Hydrosulphite (HSO3-), as a common and important chem. reagent, is widely used in everyday life, however excessive use and abuse of HSO3- can cause potential harmful effects on the environment and in biol. health. In this paper, we describe the design and preparation of a colorimetric and ratiometric fluorescence probe for the visual detection of HSO3- (excitation wavelengths were, resp., 336 nm and 520 nm). This method showed some advantages including simple preparation, high selectivity, fast response, and significant color and fluorescence ratio (F450/F594) changes in the presence of HSO3-. In addition, this probe was used successfully for the detection of HSO3- in real water samples and showed a good recovery rate range. In the experimental materials used by the author, we found 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Synthetic Route of C8H8O3)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.Synthetic Route of C8H8O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Application of 135-02-4In 2020 ,《Ag nanoparticles stabilized on cyclodextrin polymer decorated with multi-nitrogen atom containing polymer: an efficient catalyst for the synthesis of xanthenes》 was published in Molecules. The article was written by Sadjadi, Samahe; Kahangi, Fatemeh Ghoreyshi; Dorraj, Masoumeh; Heravi, Majid M.. The article contains the following contents:

In attempt to broaden the use of cyclodextrin polymer for catalytic purposes, a novel covalent hybrid system was prepared through growth of multi-nitrogen atom containing polymer (PMelamine) derived from reaction of ethylenediamine and 2,4,6-trichloro-1,3,5-triazine on the functionalized cyclodextrin polymer (CDNS). The resulting hybrid system was then utilized as a catalyst support for the immobilization of silver nanoparticles through using Cuscuta epithymum extract as a naturally-derived reducing agent. The catalytic activity of the catalyst,Ag@CDNS-N/PMelamine, for the synthesis of xanthenes through reaction of aldehydes and dimedone in aqueous media was examined The results showed high catalytic activity and recyclability of the catalyst. It was believed that cyclodextrin in the backbone of the catalyst could act both as a capping agent for Ag nanoparticles and phase transfer agent to bring the hydrophobic substrates in the vicinity of the catalytic active sites and accelerate the reaction rate. Multi-nitrogen atoms on the polymer, on the other hand, could improve the Ag NPs anchoring and suppress their leaching. In the experimental materials used by the author, we found 2-Methoxybenzaldehyde(cas: 135-02-4Application of 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Application of 135-02-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthetic Route of C8H8O2In 2019 ,《One-pot synthesis of 2-amino-4H-chromene derivatives by MNPs@Cu as an effective and reusable magnetic nanocatalyst》 was published in RSC Advances. The article was written by Ma, Wanzheng; Ebadi, Abdol Ghaffar; sabil, Mostafa shahbazi; Javahershenas, Ramin; Jimenez, Giorgos. The article contains the following contents:

In this research, MNPs@Cu as an effective and recyclable nanocatalyst was prepared and characterized using different methods including FT-IR, TGA, VSM, SEM, EDX and XRD. After the characterization of this new nanocatalyst, it was efficiently used for one-pot synthesis of 2-amino-4H-chromene derivatives I [R = Ph, 4-MeOC6H4, 4-ClC6H4, etc.], II and III [X = NH, O] via one-pot three-component Knoevenagel condensation of enolizable compounds, malononitrile and benzaldehydes under solvent-free conditions. The procedure gave the desired products I, II and III in high-to-excellent yields in short reaction times. Also this catalyst, because of its magnetic nature, could be simply restored by a permanent magnetic field and comfortably reused several times without any significant loss of its catalytic activity. The results came from multiple reactions, including the reaction of 2-Methoxybenzaldehyde(cas: 135-02-4Synthetic Route of C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Synthetic Route of C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Li, Xiang; Shen, Yang; Zhang, Guodong; Zheng, Xin; Zhao, Qing; Song, Zihe published an article in Organic Letters. The title of the article was 《Ru(II)-Catalyzed Decarbonylative Alkylation and Annulations of Benzaldehydes with Iodonium Ylides under Chelation Assistance》.Safety of 2-Hydroxy-4-methoxybenzaldehyde The author mentioned the following in the article:

A Ru(II)-catalyzed decarbonylative alkylation and annulation of salicylaldehydes and 2-aminobenzaldehydes with iodonium ylides has been developed for the synthesis of dibenzo[b,d]furans and NH-free carbazolones. The reaction proceeds smoothly under mild conditions with a low catalyst loading and a broad substrate compatibility. Notably, hydroxy and free amino groups were demonstrated to be the effective directing groups, enabling the successful aldehyde C-H bond activation and subsequent decarbonylation and annulation under the inexpensive Ru(II) catalyst. The experimental process involved the reaction of 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Safety of 2-Hydroxy-4-methoxybenzaldehyde)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.Safety of 2-Hydroxy-4-methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Li, Bai; Wang, Minghui; Gu, Xin; Chen, Jiajia; Yang, Xindi; Liu, Xuejin; Xu, Kuoxi published an article in Microchimica Acta. The title of the article was 《A hemicyanidin-based NIR fluorescent probe for detection of H2S and imaging study in cells and mice》.Recommanded Product: 2-Hydroxy-4-methoxybenzaldehyde The author mentioned the following in the article:

The selective detection of hydrogen sulfide in physiol. and pathol. processes has gained substantial attention in recent years. However, the real-time detection of hydrogen sulfide remains an elusive goal. In this work, a new type of hemicyanidin-based fluorescent “”turn-on”” probe NTR-HS (Ex = 680 nm, Em = 760 nm) was developed to detected H2S in a very short time (3 min). The fluorescence quantum yield is 0.15 and accompanied with a noticeable color change from violet to blue that can be used to detect H2S in the range 1.04 x 10-7-4 x 10-5 M with a limit of detection of 1.04 x 10-7 M. The NTR-HS probe was also used for imaging of endogenous hydrogen sulfide and mitochondrial localization in HCT116 and HeLa cells. The detection mechanism was studied through fluorescence, UV-Vis, NMR, and mass anal. Notably, the probe was successfully used to imaging H2S in mice and locating hydrogen sulfide in the large intestine of mice. In addition to this study using 2-Hydroxy-4-methoxybenzaldehyde, there are many other studies that have used 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Recommanded Product: 2-Hydroxy-4-methoxybenzaldehyde) was used in this study.

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.Recommanded Product: 2-Hydroxy-4-methoxybenzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Hao, Leiduan; Auni, Anika; Ding, Guodong; Li, Xiaoyu; Xu, Haiping; Li, Tao; Zhang, Qiang published their research in RSC Advances in 2021. The article was titled 《Selective hydroxylation of aryl iodides to produce phenols under mild conditions using a supported copper catalyst》.Application of 150-19-6 The article contains the following contents:

In this work, the selective hydroxylation of aromatic iodides RI (R = Ph, 2-methylphenyl, 2,4,6-trimethylphenyl, etc.) and 1-iodo-4-(4-iodophenyl)benzene to produce phenols ROH and 4-(4-hydroxyphenyl)phenol using an atomically dispersed copper catalyst (Cu-ZnO-ZrO2) under mild reaction conditions was reported. The reactions were conducted without the use of addnl. organic ligands, and the protection of an inert atm. environment is not required. The catalyst can be easily prepared, scalable, and is very efficient for a wide range of substrates. The catalytic reactions can be carried out with only 1.24 mol% Cu loading, which shows great potential in mass production The experimental process involved the reaction of m-Methoxyphenol(cas: 150-19-6Application of 150-19-6)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneApplication of 150-19-6

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem