Tag: 100-200

In 2022,Luo, Xiaosheng; Feng, Qiping; Wang, Ping published an article in Synthesis. The title of the article was 《Radical Addition of 4-Hydroxyquinazolines and Alkylation of Quinones by the Electro-Induced Homolysis of 4-Alkyl-1,4-dihydropyridines》.HPLC of Formula: 60656-87-3 The author mentioned the following in the article:

The formation of C(sp3)-centered radicals via the electro-induced homolysis of 4-alkyl-1,4-dihydropyridines (alkyl-DHPs) is reported. The resulting alkyl radicals reacted with 4-hydroxyquinazolines or quinones to afford 2-alkyldihydroquinazolinones or alkylated quinones. A broad range of alkyl DHPs could be used as versatile radical precursors under electrolysis conditions. This alterative strategy provided a simple and effective pathway for the construction of C(sp2)-C(sp3) and C(sp3)-C(sp3) bonds under mild conditions. In the experiment, the researchers used many compounds, for example, 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3HPLC of Formula: 60656-87-3)

2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) may be used in the following syntheses: (3S,5S)-methyl 6-benzyloxy-3,5-dihydroxyhexanoate ,(S)-5-benzyloxy-4-hydroxypentan-2-one, myxothiazols.HPLC of Formula: 60656-87-3

Referemce:
Ether – Wikipedia,
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In 2019,Organic Letters included an article by Yoo, Huen Ji; Youn, So Won. Recommanded Product: 673-22-3. The article was titled 《Zn(II)-Catalyzed One-Pot Synthesis of Coumarins from Ynamides and Salicylaldehydes》. The information in the text is summarized as follows:

Substituted coumarins and iminocoumarins were prepared regioselectively by cyclocondensation of ynamides (particularly N-alkynyl-N-methylmethanesulfonamides) with salicylaldehydes, o-hydroxyphenyl ketones, and o-aminophenyl ketones in the presence of ZnBr2. Generation of an ynamide in situ from 1-bromo-2-phenylethyne and N-methylmethanesulfonamide allowed the recycling of the methanesulfonamide through five cycles; the presence of coumarin did not inhibit the copper-catalyzed amination of the bromoalkyne. The experimental part of the paper was very detailed, including the reaction process of 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Recommanded Product: 673-22-3)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.Recommanded Product: 673-22-3

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《A new zinc(II) complex with N2O2-tetradentate Schiff-base derived from pyridoxal-S-methylthiosemicarbazone: Synthesis, characterization, crystal structure, DFT, molecular docking and antioxidant activity studies》 was written by Poladian, Qumars; Sahin, Onur; Karakurt, Tuncay; Ilhan-Ceylan, Berat; Kurt, Yasemin. Related Products of 673-22-3This research focused onzinc Schiff methylthiosemicarbazone hydroxymethoxybenzaldehyde complex preparation antioxidant; frontier mol orbital zinc Schiff methylthiosemicarbazone hydroxymethoxybenzaldehyde complex; crystal structure zinc Schiff methylthiosemicarbazone hydroxymethoxybenzaldehyde complex. The article conveys some information:

A new unsym. N2O2-tetradentate Schiff-base complex of zinc(II) was synthesized by the template reaction of pyridoxal-S-methylthiosemicarbazone and 2-hydroxy-4-methoxy-benzaldehyde as starting compounds S-methylthiosemicarbazone (1) and zinc(II) complex [Zn(L)CH3OH] (2) were characterized by elemental anal., FT-IR, UV-visible, 1H, and 13C NMR spectra. The mol. structure of 2 was determined by single crystal X-ray diffraction technique. The structure consists of a distorted square-pyramidal geometry around the central metal, Zn(II). Quantum chem. calculations were carried out using d. functional theory DFT/B3LYP, 6-31G (d), and LanL2DZ basis sets for theor. characterization of the compounds The exptl. and theor. data were compared comprehensively. The potential energy distribution (PED) anal. was performed for the assignment of vibration frequencies. In order to support in vitro studies, mol. docking studies were carried out so that the title compound can be an inhibitor of Epidermal Growth Factor Receptor (1 m17), and the relationship between calculated HOMO energies and docking studies was examined In addition, the total antioxidant capacity (as TEAC value) and free radical scavenging activity of the compounds were determined by Cupric Reducing Antioxidant Capacity (CUPRAC) and 1,1-diphenyl-2-picryl hydrazyl (DPPH) methods, resp. In the experimental materials used by the author, we found 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Related Products of 673-22-3)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.Related Products of 673-22-3

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Formula: C8H8O3In 2019 ,《Syntheses, structures and Hirschfeld analyses of trinuclear Ni(Π) salamo-type complexes》 was published in Wuji Huaxue Xuebao. The article was written by Yu, Meng; Mu, Hao-ran; Liu, Ling-zhi; Li, Na; Bai, Yang; Dong, Xiu-yan. The article contains the following contents:

Two newly designed complexes, {[Ni(L1)(n-propanol)]2(OAc)2Ni}·2(n-propanol) (1) and {[Ni(L2)(n-butanol)]2(OAc)2Ni}·2(n-butanol) (2) derived from tetradentate Salamo-type chelating ligands (H2L1=5-methoxy-2,2′-(ethylenedioxybis(azomethine))diphenol and H2L2=4,4′-dinitro-2,2′-(ethylenediyldioxybis(nitrilomethylidyne))diphenol) have been synthesized and characterized by elemental analyses, IR and UV-Vis spectra, Hirschfeld surfaces analyses and single crystal X-ray crystallog. X-ray crystallog. analyses showed that complexes 1 and 2 are all sym. trinuclear Ni(Π) complexes. Nickel(Π) in both 1 and 2 is hexa-coordinated, forming a twisted octahedral geometry. Both crystal structure and Hirschfeld surface anal. indicate that 1 and 2 form stable one-dimensional chain and two-dimensional supramol. structures, resp., by intermol. hydrogen bonding. The results came from multiple reactions, including the reaction of 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Formula: C8H8O3)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.Formula: C8H8O3

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Ether – Wikipedia,
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Reference of m-MethoxyphenolIn 2019 ,《Construction of Spirocyclic Tetrahydro-β-carbolines via Cross-Annulation of Phenols with Tryptamines in Water》 was published in Organic Letters. The article was written by Wang, Zemin; Niu, Jiabin; Zeng, Huiying; Li, Chao-Jun. The article contains the following contents:

Phenols are readily available by degradation of lignin resource. Palladium-catalyzed conversion of phenols to tetrahydro-β-carboline skeletons bearing a spirocycle at the C-1 position in water is reported. Various substituted phenols are successfully cross-annulated with different tryptamines via sequential C(Ar)-O bond cleavage of phenols, C-H bond activation of tryptamines, and C-N/C-C bond formations. This method provides a new protocol of converting lignin phenols into high-value-added compounds, such as natural product Komavine. In the experimental materials used by the author, we found m-Methoxyphenol(cas: 150-19-6Reference of m-Methoxyphenol)

m-Methoxyphenol(cas: 150-19-6) may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.Reference of m-Methoxyphenol

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Related Products of 10365-98-7In 2021 ,《Magnetic Circularly Polarized Luminescence in the Photoexcited States of Racemic [n]Helicenes (n=3-5,7) in Tetrahydrofuran and Dimethyl Sulfoxide Solutions》 appeared in ChemPhysChem. The author of the article were Toda, Hayato; Otake, Shuhei; Ito, Akari; Miyasaka, Makoto; Fujiki, Michiya; Imai, Yoshitane. The article conveys some information:

This paper reports the first magnetic circularly polarized luminescence (MCPL) characteristics of racemic helicenes, including four unsubstituted [n]helicenes (n=3,4,5,7) and two [4]helicene derivatives bearing methoxy substituents, in THF (THF) and DMSO (DMSO) solutions The value of |gMCPL| was calculated to be of the order of 10-3 T-1 within 350-430 nm under the north-up (N-up) and south-up (S-up) Faraday geometries in an external magnetic field of 1.6 T. The [n]-dependent MCPL signs were altered by the N-up and S-up geometries. In the experiment, the researchers used 3-Methoxyphenylboronic acid(cas: 10365-98-7Related Products of 10365-98-7)

3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.Related Products of 10365-98-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Xue, Sijing; Cristofol, Alex; Limburg, Bart; Zeng, Qian; Kleij, Arjan W. published an article in ACS Catalysis. The title of the article was 《Dual Cobalt/Organophotoredox Catalysis for Diastereo- and Regioselective 1,2-Difunctionalization of 1,3-Diene Surrogates Creating Quaternary Carbon Centers》.HPLC of Formula: 60656-87-3 The author mentioned the following in the article:

The synthesis of quaternary carbons RCH(OH)C(R1)(Me)CH=CH2(R = Ph, naphthalen-2-yl, 4-(prop-1-en-2-yl)cyclohex-1-en-1-yl, furan-2-yl, etc.; R1 = Ph, 4-MeOPh, 4-MePh, 4F-Ph, 4-Cl-Ph, etc.) through a catalytic stereo- and regioselective difunctionalization of 2-substituted 1,3-dienes C6H5CH(OH)C(C6H5)(CH2R2)CH=CH2 remains elusive. Here, a dual Co/photoredox-catalyzed cascade approach that addresses this challenge using modular vinyl cyclic carbonates functioning as masked 2-aryl-1,3-dienes I surrogates was presented. The latter species are conveniently prepared in situ and converted into nucleophilic Co(allyl) intermediates that are intercepted by aldehydes to afford homoallylic alcs. compound (I) with ample scope in reaction partners. The developed protocol marks a significant step forward in the use of structurally versatile 1,3-dienes I and their catalytic 1,2-hydroalkylation and 1,2-dicarbofunctionalization. In the experimental materials used by the author, we found 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3HPLC of Formula: 60656-87-3)

2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) is a non-natural aldehyde. It undergoes enantioselective Mukaiyama aldol reaction with silylketene acetal nucleophiles in the presence of C2-symmetric bis(oxazolinyl)pyridine Cu(II) complex (catalyst).HPLC of Formula: 60656-87-3

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Ether – Wikipedia,
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Tang, Huiling; Liu, Mengna; Zhu, Meiqi; Cui, Benqiang; Shi, Yanhui; Cao, Changsheng published an article in 2021. The article was titled 《C(sp2)-C(sp2) Suzuki cross-coupling of arylammonium salts catalyzed by a stable Pd-NHC complex》, and you may find the article in Tetrahedron.Formula: C7H9BO3 The information in the text is summarized as follows:

The authors developed the Suzuki-Miyaura cross-coupling of aryl ammonium salts via C-N bond activation catalyzed by an easily prepared and bench-stable palladium-N-heterocyclic carbene complex. The reaction proceeded well under mild conditions with phenylboronic acid and pinacol ester or anhydride and provided biaryls Ar1-Ar2 [Ar1 = 1-naphthyl, Ph, 2-pyridyl, etc., Ar2 = Ph, 4-MeC6H4, 4-PhC6H4, etc.] in up to 97% yield with good functional group compatibility. The direct arylation of arylamine could be performed by a two-step, one-pot process and a protocol could be performed on the gram scale. After reading the article, we found that the author used 3-Methoxyphenylboronic acid(cas: 10365-98-7Formula: C7H9BO3)

3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.Formula: C7H9BO3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Sparkes, Emily I.; Egedeuzu, Chisom S.; Lias, Billie; Sung, Rehana; Caslin, Stephanie A.; Tabatabaei Dakhili, S. Yasin; Taylor, Peter G.; Quayle, Peter; Wong, Lu Shin published an article in 2021. The article was titled 《Biocatalytic Silylation: The Condensation of Phenols and Alcohols with Triethylsilanol》, and you may find the article in Catalysts.Recommanded Product: m-Methoxyphenol The information in the text is summarized as follows:

Silicatein-α (Silα), a hydrolytic enzyme derived from siliceous marine sponges, is one of the few enzymes in nature capable of catalyzing the metathesis of silicon-oxygen bonds. It is therefore of interest as a possible biocatalyst for the synthesis of organosiloxanes. To further investigate the substrate scope of this enzyme, a series of condensation reactions with a variety of phenols and aliphatic alcs. were carried out. In general, it was observed that Silα demonstrated a preference for phenols, though the conversions were relatively modest in most cases. In the two pairs of chiral alcs. that were investigated, it was found that the enzyme displayed a preference for the silylation of the S-enantiomers. Addnl., the enzyme′s tolerance to a range of solvents was tested. Silα had the highest level of substrate conversion in the nonpolar solvents n-octane and toluene, although the inclusion of up to 20% of 1,4-dioxane was tolerated. These results suggest that Silα is a potential candidate for directed evolution toward future application as a robust and selective biocatalyst for organosiloxane chem. The experimental process involved the reaction of m-Methoxyphenol(cas: 150-19-6Recommanded Product: m-Methoxyphenol)

m-Methoxyphenol(cas: 150-19-6) may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.Recommanded Product: m-Methoxyphenol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Volpi, G.; Garino, C.; Fresta, E.; Casamassa, E.; Giordano, M.; Barolo, C.; Viscardi, G. published an article in 2021. The article was titled 《Strategies to increase the quantum yield: Luminescent methoxylated imidazo[1,5-a]pyridines》, and you may find the article in Dyes and Pigments.SDS of cas: 135-02-4 The information in the text is summarized as follows:

A series of methoxylated imidazo[1,5-a]pyridines is presented and their optical and electrochem. properties investigated and interpreted on the basis of d. functional theory calculations The photophys. properties are discussed in relation to the chem. structure. The key role of the 1,3 substitutions on the imidazo[1,5-a]pyridine nucleus on rotational barriers and on frontier MOs is discussed in relation to the exptl. hyperchromic effect, photoemission quantum yield and electrochem. properties. Depending on the position of the introduced methoxy substituents on the imidazo[1,5-a]pyridine nucleus, we are able to tune the Stokes shift and to increase the emission quantum yield from 22% to 50%. The results came from multiple reactions, including the reaction of 2-Methoxybenzaldehyde(cas: 135-02-4SDS of cas: 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.SDS of cas: 135-02-4

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Ether – Wikipedia,
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