Tag: 100-200

The author of 《Quantum Dots Arrangement and Energy Transfer Control via Charge-Transfer Complex Achieved on Poly(Phenylene Ethynylene)/Schizophyllan Nanowires》 were Shiraki, Tomohiro; Haraguchi, Shuichi; Tsuchiya, Youichi; Shinkai, Seiji. And the article was published in Chemistry – An Asian Journal in 2009. Category: ethers-buliding-blocks The author mentioned the following in the article:

Assemblies of organic and inorganic compounds in the nanoscale region have contributed to the development of novel functional materials toward future applications, including sensors and opto-electronics. The authors succeed in fabricating hybrid nanowires composed of a conjugated polymer and semiconductor quantum dots (QDs) by a supramol. assembly technique. The 1-dimensional fashion of the nanowire structure was obtained by the polymer wrapping of cationic poly(phenylene ethynylene) (PPE) with helix-forming polysaccharide schizophyllan (SPG). The electrostatic interaction between cationic PPE and anionic QDs affords the nanowires decorated with QDs. Upon addition of an acceptor mol., tetranitrofluorenone (TNF), the charge-transfer (CT) complex between PPE and TNF is formed, resulting in energy transfer from the QDs to PPE arising from the induced spectral overlap. Also, the employment of the conjugated polymer allows highly sensitive quenching of the QD’s emission by raising the transmission efficiency to the CT complexed electron deficient sites along the polymer backbone. In the experiment, the researchers used many compounds, for example, 1,4-Diethynyl-2,5-dimethoxybenzene(cas: 74029-40-6Category: ethers-buliding-blocks)

1,4-Diethynyl-2,5-dimethoxybenzene(cas: 74029-40-6) belongs to ethers.Category: ethers-buliding-blocksAlthough ethers resist hydrolysis, they are cleaved by hydrobromic acid and hydroiodic acid. Hydrogen chloride cleaves ethers only slowly.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Tamura, Yasumitsu; Fujita, Masanobu; Chen, Ling-Ching; Inoue, Minako; Kita, Yasuyuki published their research in Journal of Organic Chemistry on August 14 ,1981. The article was titled 《Regioselective metalation of the 4-position of pyridine. New and convenient alkylation and acylation of 3-amino-5-methoxypyridine》.Name: 5-Methoxy-4-methylpyridin-3-amine The article contains the following contents:

The reaction of 3-methoxy-5-pivaloylaminopyridine with BuLi at low temperature in THF gives the 4-lithiopyridines, which react with various electrophiles to give the corresponding 4-substituted 3-methoxy-5-pivaloylaminopyridines. The conversion of the 5-pivaloylamino group to other substituents via the pyridyl radical was also examined In the experiment, the researchers used 5-Methoxy-4-methylpyridin-3-amine(cas: 77903-28-7Name: 5-Methoxy-4-methylpyridin-3-amine)

5-Methoxy-4-methylpyridin-3-amine(cas: 77903-28-7) belongs to anime. Acylation is one of the most important reactions of primary and secondary amines; a hydrogen atom is replaced by an acyl group (a group derived from an acid, such as RCOOH or RSO3H, by removal of ―OH, such as RC(=O)―, RS(O)2―, and so on). Reagents may be acid chlorides (RCOC1, RSO2C1), anhydrides ((RCO)2O), or even esters (RCOOR′); the products are amides of the corresponding acids.Name: 5-Methoxy-4-methylpyridin-3-amine

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Related Products of 135-02-4In 2019 ,《Novel Fe3O4/SiO2/PPA Magnetic Nanoparticles: Preparation, Characterization, and First Catalytic Application to the Solvent- Free Synthesis of Tetrahydrobenzo[a]xanthene-11-ones》 was published in Russian Journal of Organic Chemistry. The article was written by Amarloo, F.; Zhiani, R.; Mehrzad, J.. The article contains the following contents:

Novel Fe3O4/SiO2/PPA nanoparticles were used as solid acid support in the solvent-free synthesis of 12-aryl-9,9-dimethyl-8,9,10,12-tetrahydro-11H-benzo[a]xanthen-11-ones I (R = H, 4-Me, 2-MeO, 4-MeO, 2-Cl, 4-Cl) via multicomponent condensation of aromatic aldehydes with naphthalen-2-ol and 5,5-dimethylcyclohexane-1,3-dione. The target products were obtained in good to high yields. The Fe3O4/SiO2/PPA nanoparticles were thoroughly characterized by SEM, transmission electron microscopy, Fourier-transform IR spectroscopy, and energy-dispersive C-ray spectroscopy. The new catalyst has a high activity and is environmentally friendly, heterogeneous, easily recoverable, and recyclable without loss of catalytic activity. In the experimental materials used by the author, we found 2-Methoxybenzaldehyde(cas: 135-02-4Related Products of 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Related Products of 135-02-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

HPLC of Formula: 2398-37-0In 2022 ,《Synthesis of selenopyrano[2,3-b]indol-4(9H)-ones and their C H arylation》 was published in Journal of Heterocyclic Chemistry. The article was written by Woo-Jin, Choi; Jalani, Hitesh B.; Jeong, Jin-Hyun. The article contains the following contents:

Herein, authors disclose the synthesis of selenopyrano[2,3-b]indol-4(9H)-ones and their aryl derivatives using seleno-pyran ring formation via an in situ-generated selenide reacting directly with α-halo-β-ynones of substituted indoles providing selenopyrano[2,3-b]indol-4(9H)-ones. Subsequent direct CH arylation of the these compounds by palladium-catalyzed Heck reaction enables the incorporation of aryl substituents on the selenopyrano[2,3-b]indol-4(9H)-ones scaffolds with moderate yields. This new chemo-type incorporating an indole ring may be useful for the biol. screenings. After reading the article, we found that the author used 1-Bromo-3-methoxybenzene(cas: 2398-37-0HPLC of Formula: 2398-37-0)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.HPLC of Formula: 2398-37-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Recommanded Product: 135-02-4In 2019 ,《Introduction of piperazine-1,4-diium dihydrogen phosphate as a new and highly efficient dicationic Bronsted acidic ionic salt for the synthesis of (thio)barbituric acid derivatives in water》 appeared in Journal of Molecular Structure. The author of the article were Darvishzad, Shila; Daneshvar, Nader; Shirini, Farhad; Tajik, Hassan. The article conveys some information:

A new piperazine-based dicationic Bronsted acidic ionic salt named as piperazine-1,4-diium dihydrogen phosphate was prepared After characterization by FT-IR, Mass and NMR spectroscopy, it was used as an efficient and reusable catalyst for the synthesis of 5-arylidenepyrimidine-2,4,6(1H,3H,5H)-trione and pyrano[2,3-d]pyrimidinone (thione) derivatives Some of the advantages of this method were utilization of low amount of the catalyst, ease of work-up, short reaction times, excellent yields and acceptable reusability of the catalyst. In the experiment, the researchers used many compounds, for example, 2-Methoxybenzaldehyde(cas: 135-02-4Recommanded Product: 135-02-4)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Recommanded Product: 135-02-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Electric Literature of C8H8O2In 2019 ,《Green one-pot multicomponent synthesis of pyrrolidinones using planetary ball milling process under solvent-free conditions》 appeared in Synthetic Communications. The author of the article were Khaligh, Nader Ghaffari; Mihankhah, Taraneh; Johan, Mohd Rafie. The article conveys some information:

A novel and efficient protocol was presented for the synthesis of pyrrolidinones I [R1 = H, 2-NO2, 4-Cl, etc.; R2 = Et, Me; R3 = H, 4-Me, 4-OMe, 4-NO2] via multicomponent condensation of benzaldehydes, dialkyl butynedioates and anilines using catalytic loading of 1,1′-butylene-bis(3-sulfo-3H-imidazol-1-ium)hydrogen sulfate as recyclable Bronsted acid ionic liquid through ball milling process at room temperature under solvent-free conditions. The developed method provided good to excellent yields of various pyrrolidinones in environmentally friendly conditions. Furthermore, this efficient protocol displayed a combination of the synthetic advantage of one-pot multicomponent reaction with ecol. benefits and convenience of a mechanochem. procedure. The results came from multiple reactions, including the reaction of 2-Methoxybenzaldehyde(cas: 135-02-4Electric Literature of C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Electric Literature of C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Computed Properties of C8H8O2In 2019 ,《Synthesis of New 6-[4-(2-Fluorophenylpiperazin-1-yl)]-3(2H)-Pyridazinone-2-Acetyl-2- (Substituted benzal)Hydrazone Derivatives and Evaluation of Their Cytotoxic Effects in Liver and Colon Cancer Cell Lines》 appeared in Pharmaceutical Chemistry Journal. The author of the article were Ozdemir, Zeynep; Basak-Turkmen, Nese; Ayhan, Idris; Ciftci, Osman; Uysal, Mehtap. The article conveys some information:

In this study, seven new 3(2H)-pyridazinone derivatives I (R = H, 2-Cl, 4-NMe2, 4-Me, 4-Cl, 4-Br, 2-MeO) expected to show cytotoxic activity in liver and colon cancer cell lines were synthesized. Compounds I were tested on HEP3B (liver cancer) and HTC116 (colon cancer) cell lines for cytotoxicity by using MTS [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium] proliferation assay. Human fibroblast cells were used as a safety control in these tests. Compound I (R = 2-Cl) was the most active agent with respect to HEP3B and HTC116 cell lines. In the experiment, the researchers used 2-Methoxybenzaldehyde(cas: 135-02-4Computed Properties of C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Computed Properties of C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Magee, Thomas V.; Ripp, Sharon L.; Li, Bryan; Buzon, Richard A.; Chupak, Lou; Dougherty, Thomas J.; Finegan, Steven M.; Girard, Dennis; Hagen, Anne E.; Falcone, Michael J.; Farley, Kathleen A.; Granskog, Karl; Hardink, Joel R.; Huband, Michael D.; Kamicker, Barbara J.; Kaneko, Takushi; Knickerbocker, Michael J.; Liras, Jennifer L.; Marra, Andrea; Medina, Ivy; Nguyen, Thuy-Trinh; Noe, Mark C.; Obach, R. Scott; O’Donnell, John P.; Penzien, Joseph B.; Reilly, Usa Datta; Schafer, John R.; Shen, Yue; Stone, Gregory G.; Strelevitz, Timothy J.; Sun, Jianmin; Tait-Kamradt, Amelia; Vaz, Alfin D. N.; Whipple, David A.; Widlicka, Daniel W.; Wishka, Donn G.; Wolkowski, Joanna P.; Flanagan, Mark E. published their research in Journal of Medicinal Chemistry on December 10 ,2009. The article was titled 《Discovery of Azetidinyl Ketolides for the Treatment of Susceptible and Multidrug Resistant Community-Acquired Respiratory Tract Infections》.Name: 5-Methoxy-4-methylpyridin-3-amine The article contains the following contents:

Respiratory tract bacterial strains are becoming increasingly resistant to currently marketed macrolide antibiotics. The current alternative telithromycin (1) from the newer ketolide class of macrolides addresses resistance but is hampered by serious safety concerns, hepatotoxicity in particular. We have discovered a novel series of azetidinyl ketolides that focus on mitigation of hepatotoxicity by minimizing hepatic turnover and time-dependent inactivation of CYP3A isoforms in the liver without compromising the potency and efficacy of 1. The experimental process involved the reaction of 5-Methoxy-4-methylpyridin-3-amine(cas: 77903-28-7Name: 5-Methoxy-4-methylpyridin-3-amine)

5-Methoxy-4-methylpyridin-3-amine(cas: 77903-28-7) belongs to anime. Milder oxidation, using reagents such as NaOCl, can remove four hydrogen atoms from primary amines of the type RCH2NH2 to form nitriles (R―C≡N), and oxidation with reagents such as MnO2 can remove two hydrogen atoms from secondary amines (R2CH―NHR′) to form imines (R2C=NR′). Tertiary amines can be oxidized to enamines (R2C=CHNR2) by a variety of reagents.Name: 5-Methoxy-4-methylpyridin-3-amine

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Electric Literature of C9H12O2On October 22, 2015 ,《Navigating CYP1A Induction and Arylhydrocarbon Receptor Agonism in Drug Discovery. A Case History with S1P1 Agonists》 was published in Journal of Medicinal Chemistry. The article was written by Taylor, Simon J.; Demont, Emmanuel H.; Gray, James; Deeks, Nigel; Patel, Aarti; Nguyen, Dung; Taylor, Maxine; Hood, Steve; Watson, Robert J.; Bit, Rino A.; McClure, Fiona; Ashall, Holly; Witherington, Jason. The article contains the following contents:

This article describes the finding of substantial upregulation of mRNA and enzymes of the cytochrome P 450 1A family during a lead optimization campaign for small mol. S1P1 agonists. Fold changes in mRNA up to 10 000-fold for CYP1A1 in vivo in rat and cynomolgus monkey and up to 45-fold for CYP1A1 and CYP1A2 in vitro in rat and human hepatocytes were observed Challenges observed with correlating induction in vitro and induction in vivo resulted in the implementation of a short, 4 day in vivo screening study in the rat which successfully identified noninducers. Subtle structure-activity relationships in this series of S1P1 agonists are described extending beyond planarity and lipophilicity, and the impact and considerations of AhR and CYP1A induction in the context of drug development are discussed. In addition to this study using (3-Methoxy-2-methylphenyl)methanol, there are many other studies that have used (3-Methoxy-2-methylphenyl)methanol(cas: 33797-34-1Electric Literature of C9H12O2) was used in this study.

(3-Methoxy-2-methylphenyl)methanol(cas: 33797-34-1) belongs to ethers.The C-O bonds that comprise simple ethers are strong. They are unreactive toward all but the strongest bases. Although generally of low chemical reactivity, they are more reactive than alkanes. Electric Literature of C9H12O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Electric Literature of C8H8O2In 2020 ,《Introduction of a new catalyst containing an ionic liquid bridge on nanoporous Na+- montmorillonite for the synthesis of hexahydroquinolines and 1,8-dioxo-decahydroacridines via Hantzsch condensation》 was published in Journal of Molecular Structure. The article was written by Mazloumi, Masoumeh; Shirini, Farhad. The article contains the following contents:

A new nanoporous catalyst formulated as Na+-MMT-[bip]-NH+2 HSO-4 was prepared via modification of Na+-MMT with bis-3-(trimethoxysilylpropyl)-amine and then addition of sulfuric acid. In continue the prepared reagent was identified with different methods including Fourier-transform IR spectroscopy (FT-IR), X-ray diffraction (XRD), field emission SEM (FESEM), thermogravimetric anal. (TGA), transmission electron microscopy (TEM), energy dispersive spectrometer (EDS) and CHN elemental anal. After identification the catalytic efficiency of this reagent was tested in the synthesis of hexahydroquinolines and 1,8-dioxo-decahydroacridines via Hantzsch condensations. All reactions were performed under mild conditions in the absence of solvent in high yields in short reaction times. The catalyst was also reusable for several times in both of the studied reactions. After reading the article, we found that the author used 2-Methoxybenzaldehyde(cas: 135-02-4Electric Literature of C8H8O2)

2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Electric Literature of C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem