Tag: 100-200

Reversible electrodeposition and stripping of magnesium from solvate ionic liquid-tetrabutylammonium chloride mixtures was written by Geysens, Pieter;Fransaer, Jan;Binnemans, Koen. And the article was included in RSC Advances in 2020.Computed Properties of C8H18O4 This article mentions the following:

The physicochem. properties of three new magnesium-containing solvate ionic liquids are reported. The solvation structures were analyzed by Raman spectroscopy, revealing a solvent separated ion pair structure at room temperature The reversible electrodeposition and stripping of magnesium from mixtures of these solvate ionic liquids and tetra-n-butylammonium chloride is described. The electrolytes are significantly less volatile than similar dilute electrolytes, even at elevated temperatures and the deposition current densities exceed 1 A dm^-2 at 80°C. The influence of the chloride concentration on magnesium deposition was studied with cyclic voltammetry and chronopotentiometry. It was found that the stripping of magnesium is governed by two competing reactions, and the addition of tetrabutylammonium chloride to the solvate ionic liquids was necessary to prevent passivation and efficiently strip the deposited magnesium. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2Computed Properties of C8H18O4).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Computed Properties of C8H18O4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

A novel series of 2-pyridyl-containing compounds as lysophosphatidic acid receptor antagonists: development of a nonhydrolyzable LPA₃ receptor-selective antagonist was written by Heasley, Brian H.;Jarosz, Renata;Carter, Karen M.;Jenny Van, S.;Lynch, Kevin R.;Macdonald, Timothy L.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2004.Product Details of 63071-12-5 This article mentions the following:

A recently reported dual LPA₁/LPA₃ receptor antagonist (1) has been modified to modulate the basicity, sterics, and dipole moment of the 2-pyridyl moiety. Addnl., the implications of installing nonhydrolyzable phosphate head group isosteres with regard to antagonist potency and selectivity at LPA receptors is described. This study has resulted in the development of the first nonhydrolyzable and presumably phosphatase-resistant LPA₃-selective antagonist reported to date. In the experiment, the researchers used many compounds, for example, (6-Methoxypyridin-2-yl)methanol (cas: 63071-12-5Product Details of 63071-12-5).

(6-Methoxypyridin-2-yl)methanol (cas: 63071-12-5) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Product Details of 63071-12-5

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Structure-activity relationships for osmium(II) arene phenylazopyridine anticancer complexes functionalized with alkoxy and glycolic substituents was written by Needham, Russell J.;Bridgewater, Hannah E.;Romero-Canelon, Isolda;Habtemariam, Abraha;Clarkson, Guy J.;Sadler, Peter J.. And the article was included in Journal of Inorganic Biochemistry in 2020.Synthetic Route of C5H12O3 This article mentions the following:

Twenty-four novel organometallic osmium(II) phenylazopyridine (AZPY) complexes have been synthesized and characterized; [Os(η⁶-arene)(5-RO-AZPY)X]Y, where arene = p-cym or bip, AZPY is functionalized with an alkoxyl (O-R, R = Me, Et, ⁿPr, ⁱPr, ⁿBu) or glycolic (O-{CH₂CH₂O}_nR*, n = 1-4, R* = H, Me, or Et) substituent on the pyridyl ring para to the azo-bond, X is a monodentate halido ligand (Cl, Br or I), and Y is a counter-anion (PF^–₆, CF₃SO^–₃ or IO^–₃). X-ray crystal structures of two complexes confirmed their ‘half-sandwich’ structures. Aqueous solubility depended on X, the AZPY substituents, arene, and Y. Iodido complexes are highly stable in water (X = I >>> Br > Cl), and exhibit the highest antiproliferative activity against A2780 (ovarian), MCF-7 (breast), SUNE1 (nasopharyngeal), and OE19 (oesophageal) cancer cells, some attaining nanomolar potency and good cancer-cell selectivity. Their activity and distinctive mechanism of action is discussed in relation to hydrophobicity (RP-HPLC capacity factor and Log P_o/w), cellular accumulation, electrochem. reduction (activation of azo bond), cell cycle anal., apoptosis and induction of reactive oxygen species (ROS). Two complexes show ca. 4x higher activity than cisplatin in the National Cancer Institute (NCI) 60-cell line five-dose screen. The COMPARE algorithm of their datasets reveals a strong correlation with one another, as well as anticancer agents olivomycin, phyllanthoside, bouvardin and gamitrinib, but only a weak correlation with cisplatin, indicative of a different mechanism of action. In the experiment, the researchers used many compounds, for example, 2-(2-Methoxyethoxy)ethanol (cas: 111-77-3Synthetic Route of C5H12O3).

2-(2-Methoxyethoxy)ethanol (cas: 111-77-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Synthetic Route of C5H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Metal-Free Twofold Electrochemical C-H Amination of Activated Arenes: Application to Medicinally Relevant Precursor Synthesis was written by Wesenberg, Lars J.;Diehl, Erika;Zaehringer, Till J. B.;Doerr, Carolin;Schollmeyer, Dieter;Shimizu, Akihiro;Yoshida, Jun-ichi;Hellmich, Ute A.;Waldvogel, Siegfried R.. And the article was included in Chemistry – A European Journal in 2020.Safety of 2-(4-Methoxyphenoxy)acetic acid This article mentions the following:

The efficient production of many medicinally or synthetically important starting materials suffers from wasteful or toxic precursors for the synthesis. In particular, the aromatic non-protected primary amine function represents a versatile synthetic precursor, but its synthesis typically requires toxic oxidizing agents and transition metal catalysts. The two fold electrochem. amination of activated benzene derivatives 3-R-4-R¹-5-R²-C₆H₂OC(R³)(R⁴)C(O)R⁵ [R = H, OMe; R¹ = H, OMe; R² = H, OMe; R¹R² = -CH=C(OCH₃)-CH=CH-; R³ = H, Me, Ph, 2-chlorophenyl; R⁴ = H, Me; R⁵ = methyloxidanyl, Ph] and 2,2-bis[4-(methoxycarbonylmethoxy)phenyl]propane via Zincke intermediates provides an alternative sustainable strategy for the formation of new C-N bonds of high synthetic value. This approach is used to generate benzoxazinone scaffolds I (R⁶ = F, Br, Me) that gained attention as a starting structure against castrate-resistant prostate cancer. Further improvement of the structure led to significantly increased cancer cell line toxicity. Thus, exploiting environmentally benign electrooxidation, a new versatile and powerful method based on direct C-H activation that is applicable for example the production of medicinally relevant compounds was presented. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Safety of 2-(4-Methoxyphenoxy)acetic acid).

2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Safety of 2-(4-Methoxyphenoxy)acetic acid

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Carbon-carbon main chain polymer with accumulated oligo(ethylene glycol)-substituted cyclotriphosphazenes: Study on the LCST-type phase separation of organic-inorganic poly(substituted methylene)s was written by Shimomoto, Hiroaki;Yamada, Tomohiro;Itoh, Tomomichi;Ihara, Eiji. And the article was included in Polymer Journal (Tokyo, Japan) in 2020.Electric Literature of C5H12O3 This article mentions the following:

The synthesis and characterization of organic-inorganic thermoresponsive poly(substituted methylene)s are described. Diazoacetates with oligo(ethylene glycol)-substituted cyclotriphosphazenes were synthesized, and the obtained products were employed as monomers for Pd-initiated polymerization to produce carbon-carbon main chain polymers bearing an oligo(ethylene glycol)-substituted cyclotriphosphazene on every main chain carbon atom. The resulting polymers with densely accumulated oligo(ethylene glycol) units around the polymer main chain showed lower critical solution temperature-type phase separation in an aqueous medium. In the experiment, the researchers used many compounds, for example, 2-(2-Methoxyethoxy)ethanol (cas: 111-77-3Electric Literature of C5H12O3).

2-(2-Methoxyethoxy)ethanol (cas: 111-77-3) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Electric Literature of C5H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Robust Strategy of Quasi-Solid-State Electrolytes to Boost the Stability and Compatibility of Mg Ion Batteries was written by Sun, Jianchao;Zou, Yabing;Gao, Shizhe;Shao, Lianyi;Chen, Chengcheng. And the article was included in ACS Applied Materials & Interfaces in 2020.Reference of 112-49-2 This article mentions the following:

Magnesium ion batteries (MIBs) have attracted a lot of attention because of the natural abundance of magnesium, high volumetric energy d., and superior safety. Nevertheless, MIBs are still in their infancy because of the significant challenge in developing a suitable electrolyte with low flammability, high ionic conductivity, and compatibility with the Mg anode. Herein, we construct rechargeable quasi-solid-state MIBs based on tailored polymer electrolytes. The quasi-solid state electrolyte of poly(vinylidene fluoride-co-hexafluoropropylene)-nanosized SiO₂-Mg(TFSI)₂ combines the outstanding dynamic property of a liquid electrolyte and the good stability of a solid-state electrolyte. It exhibits a highly reversible Mg²⁺ deposition-dissolution capability, high ion conductivity (0.83 mS cm^-1), and superior compatibility with the Mg metal and cathode. The quasi-solid-state MIBs with a layered titanic oxide cathode show a high reversible capacity of 129 mA h g^-1 at 50 mA g^-1 (150 W h kg^-1) without any decay after 100 cycles. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2Reference of 112-49-2).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Reference of 112-49-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis of Allenes from Allylic Alcohol Derivatives Bearing a Bromine Atom Using a Palladium(0)/Diethylzinc System was written by Ohno, Hiroaki;Miyamura, Kumiko;Tanaka, Tetsuaki;Oishi, Shinya;Toda, Ayako;Takemoto, Yoshiji;Fujii, Nobutaka;Ibuka, Toshiro. And the article was included in Journal of Organic Chemistry in 2002.Recommanded Product: 3929-47-3 This article mentions the following:

A general and efficient synthesis of allenes using a palladium(0)/diethylzinc system is described. Treatment of mesylates or trichloroacetates of (E)- or (Z)-2-bromoalk-2-en-1-ols with diethylzinc in the presence of a catalytic amount of palladium(0) affords allenes bearing an aminoalkyl, alkyl, or aryl substituent(s) in good to high yields. No transfer of chirality from the stereogenic center carrying the mesyloxy group to the allene was observed In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Recommanded Product: 3929-47-3).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Recommanded Product: 3929-47-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Design of polymer network and Li+ solvation enables thermally and oxidatively stable, mechanically reliable, and highly conductive polymer gel electrolyte for lithium batteries was written by Hashimoto, Kei;Tatara, Ryoichi;Ueno, Kazuhide;Dokko, Kaoru;Watanabe, Masayoshi. And the article was included in Journal of the Electrochemical Society in 2021.Computed Properties of C8H18O4 This article mentions the following:

Herein, we demonstrate that design of polymer network and Li+-ion solvation enables the fabrication of thermally and oxidatively stable, mech. reliable, and highly conductive polymer gel electrolytes for lithium batteries. Polymer gel electrolytes have been used for Li-ion batteries (LIB) due to their quasi-solid natures and flexible shapes. However, they frequently suffer from the high vapor pressures of the incorporated solvents, low oxidative stabilities, and poor mech. properties. To overcome these drawbacks, we fabricated a tough gel electrolyte comprising a tetra-arm poly(ethylene glycol) (TPEG) homogeneous polymer network, in which a tetraglyme(G4)-based solvate ionic liquid (SIL) was incorporated. It was intriguing to find that the solvation of Li+ ion by oxygen atoms (within G4 and TPEG), represented as [O]/[Li], governed the thermal and oxidative stabilities of the gel electrolyte, while the homogeneous network contributed to the mech. reliability and high ionic conductivity At [O]/[Li] = 5, the TPEG-based gel electrolyte with no free solvent simultaneously exhibited high thermal (>200°C) and oxidative stabilities (>4.4 V), high stretchability, and high ionic conductivity (~1 mS cm-1 at 30°C). These favorable properties of the gel electrolyte resulted in reversible charge/discharge of a 4-V-class high-voltage cathode (LiNi0.6Mn0.2Co0.2O2, NMC622). In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2Computed Properties of C8H18O4).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Computed Properties of C8H18O4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

A One-Pot Synthesis of “K(hfa) glyme” Adducts: Effect of the Polyether Length on the Ion Coordination Sphere was written by Peddagopu, Nishant;Sanzaro, Salvatore;Rossi, Patrizia;Paoli, Paola;Malandrino, Graziella. And the article was included in European Journal of Inorganic Chemistry in 2021.SDS of cas: 112-49-2 This article mentions the following:

Potassium complexes are starting to gather more and more interest from academia and industry because of their intriguing application possibilities. Novel adducts of potassium hexafluoroacetylacetonato [K(hfa)] with polyethers (monoglyme, diglyme, triglyme, and tetraglyme) were synthesized through a single step reaction and characterized through FTIR spectroscopy as well as ¹H and ¹³C NMR spectroscopy. Single crystal x-ray diffraction studies enabled the identification of fascinating K coordination polymeric networks. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2SDS of cas: 112-49-2).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.SDS of cas: 112-49-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

[1,3,4]Thiadiazolo[2,3-c][1,2,4]triazines was written by Gakhar, H. K.;Prabha, Usha;Gill, J. K.. And the article was included in Journal of the Indian Chemical Society in 1984.Product Details of 57179-35-8 This article mentions the following:

The cyclocondensation of aminotriazinethiones I (R = Me, Ph) with R¹CHO [R¹ = Ph, O₂NC₆H₄, (un)substituted 3,4-(methylenedioxy)phenyl, HO(MeO)C₆H₃] gave thiadiazolotriazines II. I (R = Me) in ether was treated with HCl gas, the ether was decanted, the residue was placed in EtOH, PhCHO and NaOAc were added, and the mixture was refluxed to give II (R = Me, R¹ = Ph). In the experiment, the researchers used many compounds, for example, 3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8Product Details of 57179-35-8).

3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Product Details of 57179-35-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem