Tag: 200-300

Garcia-Gonzalez, Ma. Carmen; Hernandez-Vazquez, Eduardo; Gordillo-Cruz, Raul E.; Miranda, Luis D. published an article in 2015, the title of the article was Ugi-derived dehydroalanines as a pivotal template in the diversity oriented synthesis of aza-polyheterocycles.SDS of cas: 887581-09-1 And the article contains the following content:

Various readily available, Ugi-derived dehydroalanines were used as pivotal templates to easily and efficiently assemble diverse pharmacol. important polyheterocyclic systems through a cascade palladium-catalyzed C-C bond formation processes (tandem reaction). Allyl, homoallyl and propargyl amine led to the formation of benzopyrrolizidinone derivatives, benzoindolizidinone derivatives and pyrazinoisoquinoline derivatives, resp., while benzylamines and o-bromobenzylamine were used as precursors of tetracyclic-fused systems and pyrazionoisoquinolindione derivatives Under optimized conditions the synthesis of the target compounds was achieved using dichlorobis(triphenylphosphine)palladium as a catalyst. Starting materials included 2-propen-1-amine (allyl amine), 2-iodobenzoic acid derivatives 2-bromobenzoic acid derivatives, 2-(benzoyloxy)acetaldehyde, isocyanides (isonitriles), 3-buten-1-amine (homoallyl amine). Dehydro amino acid amides (dehydroalanine derivatives) intermediates included N-[1-[[(1,1-dimethylethyl)amino]carbonyl]ethenyl]-2-iodo-N-(phenylmethyl)benzamide, thiophene derivatives, furan derivatives, pyrrole derivatives, indole derivatives The title compounds thus formed included (methylene)(oxo)pyrrolo[2,1-a]isoindolecarboxamides, (methylene)(oxo)pyrido[2,1-a]isoindolecarboxamides, isoindolo[2,1-b]isoquinolinecarboxamides, pyrazino[1,2-b]isoquinolinedione derivatives. The experimental process involved the reaction of (2-Bromo-5-methoxyphenyl)methanamine(cas: 887581-09-1).SDS of cas: 887581-09-1

The Article related to benzopyrrolizidinone benzoindolizidinone pyrazinoisoquinoline pyrazionoisoquinolindione preparation, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazines and Quinoxalines (Including Piperazines) and other aspects.SDS of cas: 887581-09-1

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Ether | (C2H5)2O – PubChem

On October 9, 2014, Bair, Kenneth W.; Millan, David S.; Martin, Matthew W.; Tebbe, Mark J.; Lu, Wei; Li, Hongbin; Loch, James published a patent.Application of 1417036-28-2 The title of the patent was Preparation of FASN inhibitors useful for treatment of cancer and other diseases. And the patent contained the following:

The invention relates to compounds of formula I as inhibitors of fatty acid synthase (FASN) useful alone or in combination with other drugs for the treatment of disorders such as cancer, autoimmune diseases, inflammatory disorders, and viral infections. I [wherein R1 is a (un)substituted 5- to 6-membered heterocycloalkyl; L is a (un)substituted 5- to 10-membered monocyclic or bicyclic (hetero)alkyl; A and B are independently O or S; Ar is a (un)substituted 3- to 10-membered monocyclic or bicyclic (hetero)aryl or heterocycloalkyl; R2 is H, a (un)substituted (hetero)aryl, or a (un)substituted (hetero)cycloalkyl] and pharmaceutically acceptable salts thereof are claimed and exemplified. Example compound (R)-II was prepared in a multistep process (preparation given). and evaluated for inhibition of cancer cell proliferation using PC3 cells. From the above assay III was determined to exhibit an IC50 value of <0.5 μM. The experimental process involved the reaction of 2-(3-Methoxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 1417036-28-2).Application of 1417036-28-2

The Article related to fatty acid synthase inhibitor preparation cancer, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazines and Quinoxalines (Including Piperazines) and other aspects.Application of 1417036-28-2

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On December 6, 2019, He, Jingjing; Yang, Kang; Zhao, Jianhong; Cao, Song published an article.Name: 2-((4-Methoxyphenyl)ethynyl)aniline The title of the article was LiHMDS-Promoted Palladium-Catalyzed Sonogashira Cross-Coupling of Aryl Fluorides with Terminal Alkynes. And the article contained the following:

A highly efficient Pd-catalyzed Sonogashira coupling of various aryl fluorides with terminal alkynes in the presence of LiHMDS was developed. Both unreactive electron-rich fluoroarenes and electron-poor fluoroarenes proceeded smoothly and afforded the corresponding internal alkynes in moderate to excellent yields. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Name: 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to aryl fluoride terminal alkyne sonogashira coupling palladium catalyst lhmds, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Hydrocarbons (Saturated and Unsaturated Side Chains) and other aspects.Name: 2-((4-Methoxyphenyl)ethynyl)aniline

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Ether – Wikipedia,
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On October 27, 2015, Menk, Florian; Mondeshki, Mihail; Dudenko, Dmytro; Shin, Suyong; Schollmeyer, Dieter; Ceyhun, Oliver; Choi, Tae-Lim; Zentel, Rudolf published an article.Quality Control of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene The title of the article was Reactivity Studies of Alkoxy-Substituted [2.2]Paracyclophane-1,9-dienes and Specific Coordination of the Monomer Repeating Unit during ROMP. And the article contained the following:

The polymerization of alkoxy-substituted [2.2]paracyclophane-1,9-dienes via ring-opening metathesis polymerization (ROMP) to obtain soluble poly(p-phenylenevinylene)s is a versatile method due to its living nature which enables the possibility of block copolymerization and end group modification. However, detailed studies on the reactivity behavior and the polymerization process of alkoxy-substituted [2.2]paracyclophane-1,9-dienes have not been reported so far. Herein we present a detailed study on the varying tendencies of the four isomers of dimethoxy-(2-ethylhexyloxy)-[2.2]paracyclophane-1,9-diene to undergo ROMP. Therefore, we carried out polymerization combining all individual isomers with five different metathesis catalysts and collected initiation and propagation kinetics for various combinations. Furthermore, we revealed a specific coordination of the monomer repeating unit to the catalyst during the polymerization process and succeeded to polymerize not only the pseudogeminal isomers but also one of the pseudo-ortho isomers. The experimental process involved the reaction of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene(cas: 146370-51-6).Quality Control of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene

The Article related to alkoxy paracyclophane diene isomer reactivity romp kinetics, Chemistry of Synthetic High Polymers: Polymerization Kinetics, Mechanisms, Thermodynamics, Catalysis, Catalysts and other aspects.Quality Control of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On March 31, 2005, Kalgutkar, Rajdeep S.; Palazzotto, Michael C. published a patent.Recommanded Product: 146370-51-6 The title of the patent was Arylsulfinate salts in initiator systems for polymeric reactions. And the patent contained the following:

Compositions are provided that can be used as an initiator system for free radical polymerization reactions. More specifically, the initiator systems include an electron acceptor and an electron donor. The electron donors are arylsulfinate salts having a cation that contains at least one carbon atom and either a pos. charged nitrogen atom or a pos. charged phosphorus atom. Methods of polymerization are also provided that can be used to prepare polymeric material with the initiator systems. The initiator systems can be thermal initiator systems, photoinitiator systems, or combinations thereof. The experimental process involved the reaction of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene(cas: 146370-51-6).Recommanded Product: 146370-51-6

The Article related to arylsulfinate initiator photoinitiator, Chemistry of Synthetic High Polymers: Polymerization Kinetics, Mechanisms, Thermodynamics, Catalysis, Catalysts and other aspects.Recommanded Product: 146370-51-6

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On March 6, 2020, Dhandabani, Ganesh Kumar; Shih, Chia-Ling; Wang, Jeh-Jeng published an article.Related Products of 157869-15-3 The title of the article was Acid-Promoted Intramolecular Decarbonylative Coupling Reactions of Unstrained Ketones: A Modular Approach to Synthesis of Acridines and Diaryl Ketones. And the article contained the following:

Herein, Lewis acid- or Bronsted acid-promoted intramol. C(sp2)-C(sp2) bond cleavage and a novel C(sp2)-C(sp2) bond-forming cascade reaction to synthesize the acridine motif is reported. The metal-free oxidation of the alkyne motif generated the in situ ketone group extracted via a decarbonylation reaction. The mechanistic studies revealed that the electrophilic N-iodo species triggered key decarbonylation reactions via consecutive dearomatization/aromatization reactions. In addition, this acid-promoted C-C bond activation system with internal alkynes to synthesize bis(heteroaryl) ketones is exploited. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Related Products of 157869-15-3

The Article related to acridine diaryl ketone preparation, ketone alkynylaniline intramol decarbonylative coupling reaction, internal alkyne bond activation, Heterocyclic Compounds (One Hetero Atom): Other Areno- and Diarenopyridines (Acridines, Quinolizines, etc.) and other aspects.Related Products of 157869-15-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On March 14, 2022, Cai, Chen; Lu, Yi; Yuan, Chengcheng; Fang, Zheng; Yang, Xiaobing; Liu, Chengkou; Guo, Kai published an article.Recommanded Product: 157869-15-3 The title of the article was Metal-Free C-C Cross Coupling: Electrosynthesis of Azaheterocycles through Anodic Oxidation Cyclization of 1,6-Enynes. And the article contained the following:

A straightforward synthesis of azaheterocycles has been developed through electrochem. aerobic oxidation cyclization using a user-friendly undivided electrolytic cell at room temperature under catalyst-free conditions. This green and practical electrosynthesis strategy features good functional group, diverse electronic and steric properties tolerance. Based on a series of mechanistic investigation, including isotope labeling, singlet oxygen inhibiting, superoxide radical anion inhibiting, radical-trapping, cyclic voltammetry and controlled potential electrolysis experiments, a possible N-centered radical-initiated mechanism was proposed. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Recommanded Product: 157869-15-3

The Article related to azaheterocycle preparation green chem, enyne electrochem aerobic anodic oxidation cyclization, Heterocyclic Compounds (One Hetero Atom): Other Areno- and Diarenopyridines (Acridines, Quinolizines, etc.) and other aspects.Recommanded Product: 157869-15-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Buhrmester, Claudia; Chen, Jun; Moshurchak, Lee; Jiang, Junwei; Wang, Richard Liangchen; Dahn, J. R. published an article in 2005, the title of the article was Studies of Aromatic Redox Shuttle Additives for LiFePO4-Based Li-Ion Cells.Safety of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene And the article contains the following content:

Fifty eight aromatic organic mols. were screened as chem. shuttles to provide overcharge protection for LiFePO4/graphite and LiFePO4/Li4/3Ti5/3O4 Li-ion cells. The majority of the mols. were based on methoxybenzene and on dimethoxybenzene with a variety of ligands added to explore their effect. The added ligands affect the redox potential of the mols. through their electron-withdrawing effect and affect the stability of the radical cation. Of all the mols. tested, only 2,5-di-tert-butyl-1,4-dimethoxybenzene shows an appropriate redox potential of 3.9 V vs. Li/Li+ and long-term stability during extended abusive overcharge totaling over 300 cycles of 100% overcharge per cycle. The reasons for the success of this mol. are explored. The experimental process involved the reaction of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene(cas: 146370-51-6).Safety of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene

The Article related to aromatic shuttle battery electrolyte additive secondary lithium methoxybenzene derivative, Electrochemical, Radiational, and Thermal Energy Technology: Energy-Conversion Devices and Their Components and other aspects.Safety of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On August 31, 2006, Lin, King-Fu; Fan, Yang-Liang; Chow, Hsuan-Liang published an article.Category: ethers-buliding-blocks The title of the article was Origin of the methylene bonds in poly[2-methoxy-5-(2′-ethyl-hexyloxy)-1,4-phenylenevinylene] prepared according to Gilch’s method: novel applications. And the article contained the following:

Impurities containing methylene bridges between 2-((2′-ethylhexyl)oxy)-5-methoxy-benzene mols. are inevitably formed during the synthesis of 1,4-bis(chloromethyl)-2-((2′-ethylhexyl)oxy)-5-methoxy-benzene, the monomer used in the preparation of poly[2-methoxy-5-(2′-ethyl-hexyloxy)-1,4-phenylenevinylene] (MEH-PPV), but they can be removed by double recrystallization of the monomer prior to polymerization When impurities containing methylene bridges participate in a Gilch polymerization, the methylene bonds formed in the main chains are prone to break at 200 °C, i.e., at least 150 °C below the major degradation temperature of defect-free MEH-PPV. Interestingly, the thermal treatment used to break the methylene bonds bonds present reduces the chain aggregation of MEH-PPV during film formation and induces its blends with poly(2,3-diphenyl-5-octyl-p-phenylene-vinylene) (DPO-PPV) to form a morphol. similar to that of block copolymers. Both significantly enhance the luminescence properties. The experimental process involved the reaction of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene(cas: 146370-51-6).Category: ethers-buliding-blocks

The Article related to polyphenylenevinylene synthesis monomer impurity methylene bridging exciplex, Physical Properties of Synthetic High Polymers: Analysis, Molecular Weight Determination, and Fractionation and other aspects.Category: ethers-buliding-blocks

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Ether | (C2H5)2O – PubChem

On January 5, 2021, Zeng, Qingyue; Zhang, Qiaoling published a patent.Quality Control of Benzyl(4-bromophenyl)sulfane The title of the patent was Synthesis of benzyl sulfide with high product yield. And the patent contained the following:

A simple synthesis of benzyl sulfide capable of easily converting into other types of sulfur-containing organic compounds, and important intermediate for the synthesis of many drugs, mild reaction conditions, no metal catalyst, high product yield, wide substrate applicability, and high chiral retention value is provided. The synthesis of benzyl sulfide comprises: under the condition of metal-free, benzyl trifluoromethanesulfonic acid quaternary ammonium salt and β-sulfinyl ester in 50% potassium hydroxide aqueous solution, medium reaction to obtain a desired product. The experimental process involved the reaction of Benzyl(4-bromophenyl)sulfane(cas: 53136-21-3).Quality Control of Benzyl(4-bromophenyl)sulfane

The Article related to preparation benzyl sulfide, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ethers, Sulfides, and The Corresponding Onium Compounds and other aspects.Quality Control of Benzyl(4-bromophenyl)sulfane

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem