Tag: 200-300

Zhu, Xin-Yu; Han, Ya-Ping; Li, Ming; Li, Xue-Song; Liang, Yong-Min published an article in 2018, the title of the article was Copper-Catalyzed Radical Sulfonylation of N-Propargylindoles with Concomitant 1,2-Aryl Migration.Product Details of 157869-15-3 And the article contains the following content:

A novel copper-catalyzed cascade radical sulfonylation of N-propargyl-substituted indoles with concomitant 1,2-aryl migration was described. The protocol, which has good functional-group tolerance, provides practical, versatile and atom-economical method of accessing a new class of fascinating 2-sulfonated pyrrolo[1,2-伪]indole derivatives in moderate to good yields through the formation of the new C-S, C-C and C=O bonds in a one-step. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Product Details of 157869-15-3

The Article related to copper catalyzed radical sulfonylation propargylindole aryl migration, sulfonated pyrrolo indolone atom economical preparation, crystal mol structure methoxyphenyl tosyl pyrrolo indolone and other aspects.Product Details of 157869-15-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Durka, Krzysztof; Klis, Tomasz; Serwatowski, Janusz; Wozniak, Krzysztof published an article in 2011, the title of the article was Functionalization of some benzylthioarylboronic acids by benzylic lithiation of their N-butyldiethanolamine esters or lithium (triisopropoxy)borates.Quality Control of Benzyl(4-bromophenyl)sulfane And the article contains the following content:

The reaction of benzylthioarylboronic acids protected as N-butyldiethanolamine esters or as triisopropoxyborates with organolithium bases or lithium diisopropylamide (LDA) has been investigated. The benzylic lithiation occurs selectively using LDA at -68掳. The stability of the resultant borio-lithio intermediates is strongly influenced by the position of the boron atom in the Ph ring. The reaction with various electrophiles affords new arylboronic acids substituted in the benzylic position. The experimental process involved the reaction of Benzyl(4-bromophenyl)sulfane(cas: 53136-21-3).Quality Control of Benzyl(4-bromophenyl)sulfane

The Article related to functionalization benzylthioarylboronic acid butyldiethanolamine ester triisopropoxyborate benzylic lithiation, silyl ethylthiomethyl phenylboronic acid preparation crystal mol structure and other aspects.Quality Control of Benzyl(4-bromophenyl)sulfane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On July 29, 2010, Combs, Andrew Paul; Sparks, Richard B.; Yue, Eddy Wai Tsun; Hao, Feng; Bower, Michael Jason; Zhu, Wenyu published a patent.HPLC of Formula: 887581-09-1 The title of the patent was Preparation of oxatetraazatetracyclotricosanonaene derivatives and analogs for use as JAK and ALK inhibitors. And the patent contained the following:

Title compounds I [each A independently = CR3, N, O, S, etc.; each D independently = bond, N, O, S, etc.; each E independently = N, O, S, etc.; each L independently = bond, CH2, CH2O, etc., provided at least one is other than a bond; Q = (CR1R2)m; each X independently = N or CR3; R1 and R2 independently = H, halo, alkyl, etc.; or together with the c atom to which they are attached form an (un)substituted cycloalkyl or heterocycloalkyl; each R3 independently = H, halo, CN, alkyl, etc.; R4 = H, (un)substituted alkyl, arylalkyl, etc.; m = 1 to 4], and their pharmaceutically acceptable salts, are prepared and disclosed as janus kinase (JAK) and anaplastic lymphoma kinase (ALK) inhibitors. Thus, e.g., II路TFA was prepared by amination of 2,4,5-trichloropyrimidine with 3-methoxybenzylamine followed by amination with 3-aminobenzenemethanol, bromination, cyclization. Select I were evaluated in JAK1 kinase assays, e.g., II路TFA demonstrated an IC50 value of 51 nM. The experimental process involved the reaction of (2-Bromo-5-methoxyphenyl)methanamine(cas: 887581-09-1).HPLC of Formula: 887581-09-1

The Article related to oxatetraazatetracyclotricosanonaene derivative preparation janus kinase jak inhibitor, azatetracyclotricosanonaene oxatetra analog preparation anaplastic lymphoma kinase alk inhibitor and other aspects.HPLC of Formula: 887581-09-1

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On April 1, 2016, Li, Jianxiao; Li, Chunsheng; Yang, Shaorong; An, Yanni; Wu, Wanqing; Jiang, Huanfeng published an article.Synthetic Route of 157869-15-3 The title of the article was Assembly of 3-Sulfenylbenzofurans and 3-Sulfenylindoles by Palladium-Catalyzed Cascade Annulation/Arylthiolation Reaction. And the article contained the following:

A novel and efficient palladium-catalyzed cascade annulation/arylthiolation reaction has been developed to afford functionalized 3-sulfenylbenzofuran and 3-sulfenylindole derivatives in moderate to good yields from readily available 2-alkynylphenols and 2-alkynylanilines in ionic liquids This protocol provides a valuable synthetic tool for the assembly of a wide range of 3-sulfenylbenzofuran and 3-sulfenylindole derivatives with high atom- and step-economy and exceptional functional group tolerance. Moreover, the employment of ionic liquids under mild reaction conditions makes this transformation green and practical. Furthermore, this approach enriched current C-S bond formation chem., making a valuable and practical method in synthetic and medicinal chem. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Synthetic Route of 157869-15-3

The Article related to sulfenylbenzofuran preparation, sulfenylindole preparation, benzofuran indole sulfenyl preparation, palladium catalyst cascade annulation arylthiolation alkynylphenol alkynylaniline and other aspects.Synthetic Route of 157869-15-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Lu, Fangling; Chen, Ziyue; Li, Zhen; Wang, Xiaoyan; Peng, Xinyue; Li, Cong; Li, Ru; Pei, Hongqiao; Wang, Huamin; Gao, Meng published an article in 2018, the title of the article was Copper-catalyzed alkylation of thiophenols with benzyltrimethylammonium triflates.Product Details of 53136-21-3 And the article contains the following content:

A copper-catalyzed cross coupling of thiophenols with benzyltrimethylammonium triflates was developed. Various kinds of aryl and heteroaryl thiophenols and alkylthiols demonstrated to be efficient substrates, generating the desired alkyl thioethers RSCH2R1 [R = 4-MeC6H4, CH2C6H5, 2-naphthyl, etc.; R1 = Ph, 2-MeC6H4, 4-BrC6H4, etc.] in moderate to good yields. Meanwhile, different benzyltrimethylammonium triflates could be well tolerated. Selected thioether products were further transformed into sulfoxide R2S(O)R3 [R2 = 4-MeC6H4, 4-ClC6H4, 4-BrC6H4, etc.; R3 = Ph, 4-MeC6H4, 2-IC6H4, etc.] with good efficiency. The experimental process involved the reaction of Benzyl(4-bromophenyl)sulfane(cas: 53136-21-3).Product Details of 53136-21-3

The Article related to aryl benzyl sulfoxide preparation, alkyl thioether reactant aryl benzyl sulfoxide preparation, thiophenol benzyltrimethylammonium triflate copper catalyst cross coupling alkylation and other aspects.Product Details of 53136-21-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On May 8, 2008, Kubo, Masataka; Ito, Takahito; Shoyama, Masashi published a patent.Application of 146370-51-6 The title of the patent was Organic-inorganic hybrid phosphors, their preparation, and their use for white light-emitting materials and capsule-type endoscopes. And the patent contained the following:

The organic-inorganic hybrid phosphors, useful for white light-emitting materials and capsule-type endoscopes, contain 蟺-conjugated poly(arylenevinylenes) in granular silica and are prepared by sol-gel processing of 蟺-conjugated poly(arylenevinylenes) having phosphonium end groups and alkoxysilanes. Thus, reaction of 4-methoxyphenol and 1-bromo-2-ethylhexane gave 4-(2-ethylhexyloxy)anisole, which was converted into a dialdehyde derivative (A) and diphosphonium chloride derivative (B) via a bis(chloromethyl) derivative A and B were copolymerized in CHCl3 in the presence of NaOEt to give a 蟺-conjugated poly(arylenevinylene), which was stirred with Si(OEt)4 in aqueous EtOH solution containing 2-amino-2-hydroxymethyl-1,3-propanediol dodecylsulfate salt and NH4OH to give an organic-inorganic hybrid phosphor. A UV-emitting diode chip was potted with a mixture of the phosphor, other phosphors prepared in similar manners, and silicone resins (KER-2667A and KER-2667B) to give a white light-emitting diode showing a UV peak at 373 nm and a broad spectrum with wavelength range 400-700 nm. The experimental process involved the reaction of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene(cas: 146370-51-6).Application of 146370-51-6

The Article related to polyarylenevinylene silica organic inorganic hybrid phosphor, white light emitting diode polyarylenevinylene silica, capsule endoscope polyarylenevinylene alkoxysilane soluble gel and other aspects.Application of 146370-51-6

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On January 18, 2000, Dellsperger, Simon; Dotz, Florian; Smith, Paul; Weder, Christoph published an article.Synthetic Route of 146370-51-6 The title of the article was Synthesis and optical properties of novel poly(p-phenyleneethynylene)s. And the article contained the following:

In order to explore the influence of chem. modifications on the photophys. properties of poly(p-phenyleneethynylene)s (PPEs), a series of PPE-copolymers was synthesized, employing Heck-type cross-coupling reactions. UV/Vis absorption and photoluminescence experiments clearly demonstrate that the design of PPE-copolymers which comprise conjugated segments of well-defined length and (aliphatic) spacers in a strictly alternating fashion allows to tune the bandgap to higher energies, and thus the absorption and emission maxima to shorter wavelengths. The derivatization of the PPE backbone with electron-withdrawing substituents, by contrast, is found to be significantly less effective and only leads to comparably small shifts in the absorption and emission spectra. The experimental process involved the reaction of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene(cas: 146370-51-6).Synthetic Route of 146370-51-6

The Article related to polyphenyleneethynylene preparation optical property, photoluminescence polyphenyleneethynylene electron withdrawing substituent, absorption polyphenyleneethynylene electron withdrawing substituent and other aspects.Synthetic Route of 146370-51-6

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On August 18, 2017, Xia, Xiao-Feng; Zhang, Guo-Wei; Wang, Dawei; Zhu, Su-Li published an article.Recommanded Product: 2-((4-Methoxyphenyl)ethynyl)aniline The title of the article was Visible-Light Induced and Oxygen-Promoted Oxidative Cyclization of Aromatic Enamines for the Synthesis of Quinolines Derivatives. And the article contained the following:

The dual transition metal-visible light photoredox catalysis for the synthesis of quinoline derivatives by using dioxygen as an oxygen source is developed. By using visible light, the direct oxidative cyclization of aromatic enamines with alkynes or alkenes can be achieved at mild conditions with an aid of copper or palladium catalysts, and a variety of multisubstituted quinoline derivatives could be obtained in good to moderate yields under mild reaction conditions. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Recommanded Product: 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to oxidative cyclization aromatic enamine quinoline synthesis, visible light induced oxidative cyclization aromatic enamine quinoline, oxygen promoted oxidative cyclization aromatic enamine quinoline and other aspects.Recommanded Product: 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Liang, Hao; He, Xiaobo; Zhang, Yaqi; Chen, Bin; Ouyang, Jia-sheng; Li, Yongsu; Pan, Bendu; Subba Reddy, Chitreddy V.; Chan, Wesley Ting Kwok; Qiu, Liqin published an article in 2020, the title of the article was Copper-catalyzed (4+1) and (3+2) cyclizations of iodonium ylides with alkynes.Quality Control of 2-((4-Methoxyphenyl)ethynyl)aniline And the article contains the following content:

The copper(II)-catalyzed (4+1) cyclizations and copper(I)-catalyzed (3+2) cycloadditions of iodonium ylides R(O)CC(=IC6H5)C(O)R1 [R = R1 = OMe, OEt, OCH2CF3; RR1 = -N(CH3)C(O)N(CH3)-] and 5-methyl-3-(2-phenylethynyl)pyridin-2-amine and alkynes 2-NHR2-4-R3-C6H3CCR4 (R2 = H, CH3; R3 = H, Cl; R4 = Ph, isoquinolin-4-yl, thiophen-2-yl, etc.) and 2-OH-4-R5-5-R6C6H2CCR4 (R5 = R6 = H, R5R6 = -CH=CH-CH=CH-) were successfully developed by employing efficient and safe iodonium ylides instead of traditional diazo compounds Highly functionalized di-Me (E)-3-benzylideneindoline-2,2-dicarboxylates I and II and Me 5-(2-hydroxyphenyl)-2-methoxy-4-phenylfuran-3-carboxylates III were conveniently prepared in moderate to excellent yields. The possible reaction mechanisms were also discussed. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Quality Control of 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to dimethyl benzylideneindoline dicarboxylate preparation diastereoselective, methyl hydroxyphenyl methoxyphenylfuran carboxylate preparation, iodonium ylide alkyne cycloaddition copper catalyst and other aspects.Quality Control of 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Li, Sifeng; Wang, Zihao; Xiao, Haitao; Bian, Zhaoxiang; Wang, Jun published an article in 2020, the title of the article was Enantioselective synthesis of indole derivatives by Rh/Pd relay catalysis and their anti-inflammatory evaluation.Quality Control of 2-((4-Methoxyphenyl)ethynyl)aniline And the article contains the following content:

An efficient Rh/Pd relay catalyzed intermol. and cascade intramol. hydroamination for the synthesis of exclusive trans 1-indolyl dihydronaphthalenols (up to 88% yield, 99% ee) I [R = n-Bu, 3-thienyl, phenyl; R1 = H, 5,8-di-Me, 5,8-di-MeO, etc.] was described under mild conditions. Moreover, the in-silico and in-vitro screening showed that the novel 1-indolyl dihydronaphthalenol products were potent lead compounds for treating inflammation disease. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Quality Control of 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to oxabenzonorbornadiene phenylethynyl aniline palladium rhodium tandem enantioselective diastereoselective hydroamination, indolyl dihydronaphthalenol preparation antiinflammatory mol docking and other aspects.Quality Control of 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem