Tag: 200-300

Kondoh, Azusa; Terada, Masahiro published an article in 2018, the title of the article was Bronsted Base-Catalyzed Umpolung Intramolecular Cyclization of Alkynyl Imines.Safety of 2-((4-Methoxyphenyl)ethynyl)aniline And the article contains the following content:

A novel “umpolung” intramol. cyclization of alkynyl imines, in which the electrophilic imine sp2-carbon formally serves as a nucleophilic site, was developed under Bronsted base catalysis. The reaction involves the unprecedented catalytic generation of α-aminoester enolates from α-iminoesters via the 1,2-addition of the anion of a secondary phosphite to an imine moiety followed by the [1,2]-rearrangement of a dialkoxyphosphoryl moiety from carbon to nitrogen, which is a formal umpolung process, and the intramol. addition to an alkyne. This is a rare example of a [1,2]-rearrangement of a dialkoxyphosphoryl moiety from carbon to nitrogen to generate an α-amino carbanion and the first catalytic carbon-carbon bond forming reaction utilizing the resulting carbanion as a nucleophile. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Safety of 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to bronsted base catalyst umpolung intramol cyclization alkynyl imine, crystal structure mol phosphonate indoline preparation stereoselective, brønsted base catalysis, intramolecular cyclization, organocatalysts, rearrangement, umpolung and other aspects.Safety of 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On March 29, 2021, He, Yu-Ping; Cao, Jian; Wu, Hua; Wang, Qian; Zhu, Jieping published an article.Safety of 2-((4-Methoxyphenyl)ethynyl)aniline The title of the article was Catalytic Enantioselective Aminopalladation-Heck Cascade. And the article contained the following:

Domino processes initiated by intramol. nucleopalladation of alkynes have been developed into powerful synthetic tools for the synthesis of functionalized heterocycles. However, a catalytic enantioselective version of this class of reactions remains scarce. We report herein that reaction of 2-alkynylanilines with prochiral cyclopentenes in the presence of a catalytic amount of Pd(OAc)2, a chiral bidentate pyrox ligand and O2 as terminal oxidant affords the structurally diverse indole-cyclopentene conjugates, e.g., I, bearing two stereocenters in a highly diastereo- and enantio-selective manner. One of the products is converted to a heavily functionalized tetracyclic indolinone derivative The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Safety of 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to alkynylaniline cyclopentene diastereoselective enantioselective palladium pyrox aminopalladation heck cascade, indole cyclopentene stereoselective preparation, asymmetric synthesis, domino reactions, homogeneous catalysis, nucleopalladation, oxidative heck reactions and other aspects.Safety of 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On September 15, 1994, Wudl, Fred; Hoger, Sigurd published a patent.Reference of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene The title of the patent was Highly soluble, conductive, luminescent polyphenylenevinylenes, and products and uses thereof. And the patent contained the following:

Soluble, fast doping and de-doping, conductive, electroluminescent π-conjugated polymers I [R1 = H; hydrocarbyl, or OR3, R2 = H or Me, R3 = (mono- or polyhydroxy) branched C6-30 hydrocarbyl or C1-10 esters, C1-10 ethers, (poly)furanosyl, (poly)pyranosyl of the hydroxy derivatives; A is O, C, S, N or a single bond; n, m = 1-4; o = 1-2, x ≥ 1, y ≥ 0 and x + y > 20] are manufactured for use in electrostatic and electromagnetic interference shields, molded articles, and especially in electroluminescent layers, films and fibers for use in light-emitting diodes for tech. devices. A method for sensing a dopant within a designated area is described by exposing an amount of a dopant to ≥1 I. An improved method is described for transducing elec. energy into visible light by means of a light-emitting diode containing I. A typical polymer was manufactured by polymerization of 2,5-bis(chloromethyl)-1-methoxy-4-(2-ethylhexyloxy)benzene 24 h in THF in the presence of tert-BuOK. The experimental process involved the reaction of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene(cas: 146370-51-6).Reference of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene

The Article related to soluble elec conductive electroluminescent polyphenylenevinylene, electrostatic shield polyphenylenevinylene, bischloromethyl methoxyethylhexyloxybenzene polymer soluble elec conductive, electromagnetic shield polyphenylenevinylene, led device polyphenylenevinylene and other aspects.Reference of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On September 9, 2022, Xu, Ren-Rui; Bao, Xuanzhang; Huo, Yong-Wang; Miao, Ren-Guan; Wen, Dan; Dai, Weiqi; Qi, Xinxin; Wu, Xiao-Feng published an article.Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline The title of the article was Palladium-Catalyzed Domino Carbopalladation/Carbonylative Cyclization: Synthesis of Heterocycles bearing Oxindoles and 3-Acylbenzofuran/3-Acylindole Moieties. And the article contained the following:

A novel and straightforward methodol. for palladium-catalyzed carbopalladation-initiated domino carbonylative cyclization to construct bisheterocycles was established. With TFBen as an efficient and convenient CO source, the protocol wass capable of generating oxindole and 3-acylbenzofuran/3-acylindole moieties from the corresponding N-(o-iodoaryl)acrylamides and o-alkynylphenols/o-alkynylanilines with the formation of three C-C bonds and one C-O/C-N bond in a single one-step operation. A wide range of bisheterocycles bearing oxindoles and 3-acylbenzofurans/3-acylindoles were prepared in moderate to excellent yields with good functional group tolerance. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to iodophenyl acrylamide ethynylphenol tfben palladium tandem carbonylative heterocyclization, benzofuranyl oxindolyl ethanone preparation, ethynylaniline iodoaryl acrylamide tfben palladium tandem carbonylative heterocyclization, oxindolyl indolylethanone preparation and other aspects.Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On November 2, 2016, Le, Christine M.; Sperger, Theresa; Fu, Rui; Hou, Xiao; Lim, Yong Hwan; Schoenebeck, Franziska; Lautens, Mark published an article.Reference of 2-((4-Methoxyphenyl)ethynyl)aniline The title of the article was Stereoselective Synthesis of Methylene Oxindoles via Palladium(II)-Catalyzed Intramolecular Cross-Coupling of Carbamoyl Chlorides. And the article contained the following:

In the presence of PdCl2(PhCN)2 in toluene, arylalkynylphenylcarbamoyl chlorides such as I underwent regio- and stereoselective intramol. cross-coupling to yield chloromethyleneoxindoles such as II. The reaction proceeds under mild conditions, is insensitive to the presence of moisture and air, formed products in >95:5 Z:E selectivity in nearly all cases and is readily scalable. Product isomerization studies and calculations of the transition state structures and energies for pathways leading to product regioisomers and diastereomers were used to study the mechanism of the reaction. The calculations provide support for a mechanism involving oxidative addition into the carbamoyl chloride bond to generate a high valent PdIV species, which then undergoes facile C-C reductive elimination to form the final product. I underwent stereoselective substitution and Suzuki cross-coupling reactions. The structures of a (phenylchloromethylene)oxindole, a chlorophenylquinolinone byproduct, and the substitution product of II with benzylthiol were determined by X-ray crystallog. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Reference of 2-((4-Methoxyphenyl)ethynyl)aniline

The Article related to chloromethylene oxindole regioselective diastereoselective preparation, palladium catalyst regioselective stereoselective cyclization arylalkynyl phenylcarbamoyl chloride, intramol regioselective stereoselective cross coupling arylalkynyl phenylcarbamoyl chloride and other aspects.Reference of 2-((4-Methoxyphenyl)ethynyl)aniline

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On March 30, 2020, Karmel, Caleb; Rubel, Camille Z.; Kharitonova, Elena V.; Hartwig, John F. published an article.Safety of 2-(4-Methoxythiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane The title of the article was Iridium-Catalyzed Silylation of Five-Membered Heteroarenes: High Sterically Derived Selectivity from a Pyridyl-Imidazoline Ligand. And the article contained the following:

The steric effects of substituents on five-membered rings are less pronounced than those on six-membered rings because of the difference in bond angles. Thus, the regioselectivities of reactions of five-membered heteroarenes that occur with selectivities dictated by steric effects, such as the borylation of C-H bonds, were poor in many cases. The authors report that the silylation of five-membered-ring heteroarenes occurs with high sterically derived regioselectivity when catalyzed by the combination of [Ir(cod)(OMe)]2 (cod = 1,5-cyclooctadiene) and a phenanthroline ligand or a new pyridyl-imidazoline ligand that further increases the regioselectivity. The silylation reactions with these catalysts produce high yields of heteroarylsilanes from functionalization at the most sterically accessible C-H bonds of these rings under conditions that the borylation of C-H bonds with previously reported catalysts formed mixtures of products or products that are unstable. The heteroarylsilane products undergo cross-coupling reactions and substitution reactions with ipso selectivity to generate heteroarenes that bear halogen, aryl, and perfluoroalkyl substituents. The experimental process involved the reaction of 2-(4-Methoxythiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 1073339-22-6).Safety of 2-(4-Methoxythiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

The Article related to iridium catalyzed silylation borylation five membered heteroarene steric effects, heteroarene silylated stereoselective preparation, borane heteroarene derivative preparation, c−h functionalization, heteroarenes, iridium catalysis, regioselectivity, silylation and other aspects.Safety of 2-(4-Methoxythiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Gong, Xinxing; Chen, Mo; Yao, Liangqing; Wu, Jie published an article in 2016, the title of the article was Facile Assembly of Benzo[b]naphtho[2,3-d]azocin-6(5 H)-ones by a Palladium-Catalyzed Double Carbometalation.Electric Literature of 157869-15-3 And the article contains the following content:

The palladium-catalyzed reaction of 2-alkynylanilines with 2-(2-bromobenzylidene)cyclobutanone as an efficient route to 7,8-dihydrobenzo[b]naphtho[2,3-d]azocin-6(5 H)-ones was developed. The fused eight-membered ring was constructed conveniently. During the reaction process, double carbometalation was involved, which resulted in excellent selectivity with the formation of three new bonds. This transformation is highly efficient and leads to fused polycycles in good to excellent yields with good functional group tolerance. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Electric Literature of 157869-15-3

The Article related to benzonaphthoazocinone preparation palladium catalyzed double carbometalation, fused eight membered polycycle preparation alkynylaniline bromobenzylidene cyclobutanone reaction, domino reactions, fused-ring systems, nitrogen heterocycles, palladium, polycycles and other aspects.Electric Literature of 157869-15-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On February 17, 1999, Jin, Sung-Ho; Kim, Woo-Hong; Son, Byung-Hee; Song, In-Sung; Han, Eun-Mi published a patent.Electric Literature of 146370-51-6 The title of the patent was Organic electroluminescent polymer for light-emitting diode and devices therefrom. And the patent contained the following:

A light-emitting polymer for an electroluminescent display comprises a polymer having a dialkylphenylene moiety and a carbazole moiety I, where R1-R3 are independently C2-13 aliphatic alkyl or C5-16 branched alkyl; p = 5-100; and/or a polymer having an oxadiazole moiety and a poly(p-phenylenevinylene) moiety, and optionally a conventional polymer and a lower-mol. fluorescent dye. The polymer is applied to a light-emitting layer of a light-emitting diode having a cathode/light-emitting layer/anode structure, a cathode/buffer layer/light-emitting layer/anode structure, or a cathode/hole-transporting layer/light-emitting layer/electron-transporting layer/anode structure. Thus, a 2,5-bis(p-bromophenyl)-1,3,4-oxadiazole-1-methoxy-4-(2-ethylhexyloxy)-2,5-phenylboronic acid copolymer (monomer preparations given) was prepared, which was soluble in an organic solvent and showed excellent electron transport properties. The experimental process involved the reaction of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene(cas: 146370-51-6).Electric Literature of 146370-51-6

The Article related to electroluminescent polymer preparation light emitting diode, carbazole dialkylphenylene polymer light emitting diode, oxadiazole phenylenevinylene polymer light emitting diode, bromophenyloxadiazole phenylboronic acid copolymer preparation electroluminescent and other aspects.Electric Literature of 146370-51-6

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On August 22, 2019, Stoessel, Philipp; Auch, Armin published a patent.Category: ethers-buliding-blocks The title of the patent was Iridium complexes with hexadentate tris-cyclometalated arylpyridine ligands as triplet emitters for organic electroluminescent devices. And the patent contained the following:

Iridium complexes with hexadentate 1,3,5-benzenetriyl-bridged tris-cyclometalated arylpyridine ligands, e.g., of the type I (1, X = H, D; Ar = Ph, 4-PhC6H4, 4-PhC6H4C6H4, heterocyclyl; R1 = Me, Ph, tBu, CD3, cyclopenteno, etc.) were prepared by Sonogashira coupling of 1-chloro-3,5-diethynylbenzene with arylpyridine bromides with subsequent hydrogenation or deuteration and Suzuki coupling with appropriate aryl bromides or boronates. Bromination of the complexes in 4-position relative to cyclometalation site with subsequent cyanation or Suzuki coupling afforded modified complexes 1. The complexes 1 were examined for their electroluminescence by constructing test OLED devices according to standard protocol by either vacuum or solution-based processes. The experimental process involved the reaction of 2-(3-Methoxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 1417036-28-2).Category: ethers-buliding-blocks

The Article related to iridium cyclometalated arylpyridine hexadentate benzenetriyl bridged complex preparation electroluminescence, suzuki sonogashira coupling cyclometalation preparation iridium hexadentate arylpyridine complex, triplet emitter oled iridium hexadentate cyclometalated arylpyridine complex and other aspects.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Vonnegut, Chris L.; Shonkwiler, Airlia M.; Khalifa, Muhammad M.; Zakharov, Lev N.; Johnson, Darren W.; Haley, Michael M. published an article in 2015, the title of the article was Facile Synthesis and Properties of 2-λ5-Phosphaquinolines and 2-λ5-Phosphaquinolin-2-ones.HPLC of Formula: 157869-15-3 And the article contains the following content:

Treatment of 2-ethynylanilines with P(OPh)3 gives either 2,2-diphenoxy-2-λ5-phosphaquinolines or 2-phenoxy-2-λ5-phosphaquinolin-2-ones under transition-metal-free conditions. This reaction offers access to an underexplored heterocycle, which opens up the study of the fundamental nature of the N:PV double bond and its potential for delocalization within a cyclic π-electron system. This heterocycle can serve as a carbostyril mimic, with application as a bioisostere for pharmaceuticals based on the 2-quinolinone scaffold. It also holds promise as a new fluorophore, since initial screening reveals quantum yields upwards of 40 %, Stokes shifts of 50-150 nm, and emission wavelengths of 380-540 nm. The phosphaquinolin-2-ones possess one of the strongest solution-state dimerization constants for a D-A system (130 Μ-1) owing to the close proximity of a strong acceptor (P:O) and a strong donor (phosphonamidate N-H), which suggests that they might hold promise as new H bonding hosts for optoelectronic sensing. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).HPLC of Formula: 157869-15-3

The Article related to crystal structure optimized phosphaquinoline phosphaquinolinone preparation fluorescence dimerization, mol structure optimized phosphaquinoline phosphaquinolinone preparation fluorescence dimerization, alkynes, dimerization, fluorescent probes, phosphazenes, phosphorus heterocycles and other aspects.HPLC of Formula: 157869-15-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem