Tag: 200-300

Buyens, Dominique M. S.; Pilcher, Lynne A.; Roduner, Emil published their research in ChemPhysChem in 2021. The article was titled 《Towards a Molecular Understanding of Cation-Anion Interactions and Self-aggregation of Adeninate Salts in DMSO by NMR and UV Spectroscopy and Crystallography》.Application of 33100-27-5 The article contains the following contents:

Rare anionic forms of nucleic acids play a significant biol. role and lead to spontaneous mutations and replication and translational errors. There is a lack of information surrounding the stability and reactivity of these forms. Ion pairs of mono-sodium and -potassium salts of adenine exist in DMSO solution with possible cation coordination sites at the N1, N7 and N9 atoms of the purine ring. At increasing concentrations π-π stacked dimers are the predominant species of aggregates followed by higher order aggregation governed by coordination to metal cations in which the type of counter ion present has a central role in the aggregate formation. In addition to this study using 1,4,7,10,13-Pentaoxacyclopentadecane, there are many other studies that have used 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Application of 33100-27-5) was used in this study.

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Application of 33100-27-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Palladium-catalyzed selective defluorinative sulfenylation for the synthesis of fluorovinylthioethers》 was written by He, Shi-Yu; Zhang, Xing-Guo. Formula: C12H10S2 And the article was included in Organic Chemistry Frontiers in 2020. The article conveys some information:

An efficient transformation of trifluoromethylated compounds to monofluoroalkenes RCH=C(F)SR1 [R = Ph, 4-MeC6H4, 3-FC6H4, etc.; R1 = Ph, Bn, 2-thienyl, etc.] was developed through Pd-catalyzed selective defluorinative sulfenylation. Variety of α-fluorovinylthioethers RCH=C(F)SR1 were prepared in good yields from α-trifluoromethylated benzyl bromides and odorless disulfides. In addition to this study using 1,2-Diphenyldisulfane, there are many other studies that have used 1,2-Diphenyldisulfane(cas: 882-33-7Formula: C12H10S2) was used in this study.

1,2-Diphenyldisulfane(cas: 882-33-7) belongs to ethers.Although ethers resist hydrolysis, they are cleaved by hydrobromic acid and hydroiodic acid. Hydrogen chloride cleaves ethers only slowly. Formula: C12H10S2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《Bioinspired Palladium Nanoparticles Supported on Soil-Derived Humic Acid Coated Iron-Oxide Nanoparticles as Catalyst for C-C Cross-Coupling and Reduction Reactions》 were Chinchole, Anurag N.; Dubey, Abhishek V.; Kumar, A. Vijay. And the article was published in Catalysis Letters in 2019. HPLC of Formula: 529-28-2 The author mentioned the following in the article:

Palladium supported on humic acid-coated magnetite nanoparticles was prepared as a recyclable catalyst for Suzuki coupling reactions of aryl iodides, bromides, and diazonium tetrafluoroborates with arylboronic acids, for stereoselective Heck reactions of styrene with aryl bromides and iodides, and for hydrogenation reactions of diaryl alkenes using aqueous ethanol or methanol as solvents. In the experimental materials used by the author, we found 1-Iodo-2-methoxybenzene(cas: 529-28-2HPLC of Formula: 529-28-2)

1-Iodo-2-methoxybenzene(cas: 529-28-2) participates in palladium catalyzed enantioselective Heck arylation of 2,3-dihydrofuran in the presence of chiral ionic liquids containing L-prolinate and L-lactate anions and non-chiral quaternary ammonium cations.HPLC of Formula: 529-28-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,ACS Chemical Biology included an article by Takashima, Ippei; Kusamori, Kosuke; Hakariya, Hayase; Takashima, Megumi; Vu, Thi Hue; Mizukami, Yuya; Noda, Naotaka; Takayama, Yukiya; Katsuda, Yousuke; Sato, Shin-ichi; Takakura, Yoshinobu; Nishikawa, Makiya; Uesugi, Motonari. COA of Formula: C9H19NO4. The article was titled 《Multifunctionalization of Cells with a Self-Assembling Molecule to Enhance Cell Engraftment》. The information in the text is summarized as follows:

Cell-based therapy is a promising approach to restoring lost functions to compromised organs. However, the issue of inefficient cell engraftment remains to be resolved. Herein, we take a chem. approach to facilitate cell engraftment by using self-assembling mols. which modify two cellular traits: cell survival and invasiveness. In this system, the self-assembling mol. induces syndecan-4 clusters on the cellular surface, leading to enhanced cell viability. Further integration with Halo-tag technol. provided this self-assembly structure with matrix metalloproteinase-2 to functionalize cells with cell-invasion activity. In vivo experiments showed that the pretreated cells were able to survive injection and then penetrate and engraft into the host tissue, demonstrating that the system enhances cell engraftment. Therefore, cell-surface modification via an alliance between self-assembling mols. and ligation technologies may prove to be a promising method for cell engraftment. In addition to this study using tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate, there are many other studies that have used tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6COA of Formula: C9H19NO4) was used in this study.

tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6) belongs to ethers.Ethers do have nonbonding electron pairs on their oxygen atoms, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.COA of Formula: C9H19NO4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Applied Surface Science included an article by Fehr, Julia M.; McKenas, Catherine G.; Liu, Benedict; Lockett, Matthew R.. Name: 1,4,7,10,13-Pentaoxacyclopentadecane. The article was titled 《Azide-alkyne click reactions to prepare chemically modified amorphous carbon electrodes》. The information in the text is summarized as follows:

Current chemistries used to modify the surfaces of metal oxide semiconductor films are susceptible to hydrolysis and degrade at high, pos. potentials. Amorphous C (aC) films are an attractive alternative to metal oxides for the preparation of chem. modified electrodes, with surfaces and surface chemistries that are stable under atm. conditions and in solution Here, the authors prepared azide-terminated aC films, which were further modified with a Cu catalyzed azide-alkyne click reaction. The authors used XPS and cyclic voltammetry to show this modification strategy was selective to films containing azide group, enabling a new means of preparing modified aC electrodes. The experimental part of the paper was very detailed, including the reaction process of 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Name: 1,4,7,10,13-Pentaoxacyclopentadecane)

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Name: 1,4,7,10,13-Pentaoxacyclopentadecane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2018,Vasta, James D.; Corona, Cesear R.; Wilkinson, Jennifer; Zimprich, Chad A.; Hartnett, James R.; Ingold, Morgan R.; Zimmerman, Kristopher; Machleidt, Thomas; Kirkland, Thomas A.; Huwiler, Kristin G.; Ohana, Rachel Friedman; Slater, Michael; Otto, Paul; Cong, Mei; Wells, Carrow I.; Berger, Benedict-Tilman; Hanke, Thomas; Glas, Carina; Ding, Ke; Drewry, David H.; Huber, Kilian V. M.; Willson, Timothy M.; Knapp, Stefan; Muller, Susanne; Meisenheimer, Poncho L.; Fan, Frank; Wood, Keith V.; Robers, Matthew B. published 《Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of Cellular ATP on Target Engagement》.Cell Chemical Biology published the findings.Name: tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate The information in the text is summarized as follows:

For kinase inhibitors, intracellular target selectivity is fundamental to pharmacol. mechanism. Although a number of acellular techniques have been developed to measure kinase binding or enzymic inhibition, such approaches can fail to accurately predict engagement in cells. Here we report the application of an energy transfer technique that enabled the first broad-spectrum, equilibrium-based approach to quant. profile target occupancy and compound affinity in live cells. Using this method, we performed a selectivity profiling for clin. relevant kinase inhibitors against 178 full-length kinases, and a mechanistic interrogation of the potency offsets observed between cellular and biochem. anal. For the multikinase inhibitor crizotinib, our approach accurately predicted cellular potency and revealed improved target selectivity compared with biochem. measurements. Due to cellular ATP, a number of putative crizotinib targets are unexpectedly disengaged in live cells at a clin. relevant drug dose. In the part of experimental materials, we found many familiar compounds, such as tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6Name: tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate)

tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6) belongs to ethers. Ethers lack the hydroxyl groups of alcohols. Name: tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2017,Hao, Hongye; Deng, Ya; Wu, Yingke; Liu, Siyuan; Lin, Weiwei; Li, Jiehua; Luo, Feng; Tan, Hong published 《Synthesis of biodegradable waterborne phosphatidylcholine polyurethanes for soft tissue engineering applications》.Regenerative Biomaterials published the findings.HPLC of Formula: 139115-91-6 The information in the text is summarized as follows:

To further improve the biocompatibility of polyurethanes, a new lysine 2-(2-aminoethoxy)ethanol phosphatidylcholine (LAPC) is synthesized to use as chain extender for preparing a series of phosphatidylcholine polyurethanes (PCPUs). Poly (ε-caprolactone) (PCL) and poly(ethylene glycol) (PEG) are used as soft segments, and L-lysine Et ester diisocyanate (LDI), LAPC and L-lysine are used as hard segments. The obtained PCPUs exhibit appropriate mech. properties with break elongation of 1000-1700%, tensile strength of 7-22 MPa, and relatively high elastic modulus of 11-18 MPa, which could admirably satisfy the requirement for soft tissue engineering scaffolds. The phosphatidylcholine structures can increase the hydrophilicity of PCPU surfaces, which effectively reduce protein adsorption and platelet adhesion while promoting the cell proliferation. In addition, the LAPC chain extender, PCPU films and ultimate degradation products of PCPUs are proved to be nontoxic in cytotoxicity test. More interestingly, the cytokine release test of macrophages manifests that both LAPC and PCPU degradation products could effectively improve the proliferation of macrophages and induce them into a wound-healing phenotype. Thus, the obtained PCPUs have greatly potential applications of soft tissue engineering scaffolds for tissue repair and wound healing. After reading the article, we found that the author used tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6HPLC of Formula: 139115-91-6)

tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6) belongs to ethers.Oxygen is more electronegative than carbon, thus the alpha hydrogens of ethers are more acidic than those of simple hydrocarbons. HPLC of Formula: 139115-91-6 They are far less acidic than alpha hydrogens of carbonyl groups (such as in ketones or aldehydes), however.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Computed Properties of C12H10S2In 2019 ,《Synthesis of Symmetrical Diorganyl Disulfides Employing WEB as an Eco-friendly Oxidative System》 was published in ChemistrySelect. The article was written by Leitemberger, Andrielli; Boehs, Lucas Martins C.; Rosa, Clarissa Helena; Silva, Cleiton Da; Galetto, Fabio Z.; Godoi, Marcelo. The article contains the following contents:

A straightforward and environmentally benign methodol. for the preparation of sym. diorganyl disulfides via oxidation of thiols, under open atm. was reported. Water Extract of Banana peel ash (WEB) was conveniently employed as a selective and eco-friendly system for the oxidative dimerization of thiols, affording the corresponding disulfides in very good yields. The experimental process involved the reaction of 1,2-Diphenyldisulfane(cas: 882-33-7Computed Properties of C12H10S2)

1,2-Diphenyldisulfane(cas: 882-33-7) belongs to ethers.Computed Properties of C12H10S2Although ethers resist hydrolysis, they are cleaved by hydrobromic acid and hydroiodic acid. Hydrogen chloride cleaves ethers only slowly.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Singh, Pooja S.; Ghadiyali, Mohammed; Chacko, Sajeev; Kamble, Rajesh M. published an article in Journal of Luminescence. The title of the article was 《D-A-D based pyrido-pyrazino[2,3-b]indole amines as blue-red fluorescent dyes: Photophysical, aggregation-induced emission, electrochemical and theoretical studies》.Product Details of 101-70-2 The author mentioned the following in the article:

Herein donor-acceptor-donor (D-A-D) structured, pyridopyrazino[2,3-b]indole amines 2-6 were designed and synthesized via C-N coupled Buchwald-Hartwig amination reaction and characterized by spectroscopic methods. C-N coupling in mols. offers intramol. charge transfer (ICT) transitions at longer wavelengths (λmax = 400-459 nm) in absorption spectra reminiscent D-A assembly. Dyes covers broad range of emission and emit in blue to red region with emission maxima 433-600 nm in solvent and solid film. Dyes 2, 5 and 6 explore the aggregation-induced emission (AIE) characteristics. Further C-N blending of various donor with pyridopyrazino[2,3-b]indole acceptor results in suppressed band gap (1.99-2.43 eV) and comparable HOMO (-5.17 to -5.71 eV) and LUMO (-3.18 to -3.28 eV) energies with reported small organic ambipolar materials. DFT and TDDFT calculations agree with the exptl. opto-electrochem. data. Moreover, computed small singlet and triplet excitation energy difference (ΔEST (0.01-0.14 eV)) suggest thermally activated delayed fluorescent (TADF) emitting properties of dyes. Thus pyridopyrazino[2,3-b]indole amine dyes propose their potential application in optoelectronic devices. After reading the article, we found that the author used Bis(4-methoxyphenyl)amine(cas: 101-70-2Product Details of 101-70-2)

Bis(4-methoxyphenyl)amine(cas: 101-70-2) is a diphenylamine derivative used as a chemical additive for cured rubber.Bis(4-methoxyphenyl)amine is highly toxic and may potentially induce chromosome abberation.Product Details of 101-70-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Shin, Seung-Jae; Kim, Dong Hyun; Bae, Geunsu; Ringe, Stefan; Choi, Hansol; Lim, Hyung-Kyu; Choi, Chang Hyuck; Kim, Hyungjun published an article in 2022. The article was titled 《On the importance of the electric double layer structure in aqueous electrocatalysis》, and you may find the article in Nature Communications.COA of Formula: C10H20O5 The information in the text is summarized as follows:

To design electrochem. interfaces for efficient elec.-chem. energy interconversion, it is critical to reveal the elec. double layer (EDL) structure and relate it with electrochem. activity; nonetheless, this has been a long-standing challenge. Of particular, no mol.-level theories have fully explained the characteristic two peaks arising in the potential-dependence of the EDL capacitance, which is sensitively dependent on the EDL structure. We herein demonstrate that our first-principles-based mol. simulation reproduces the exptl. capacitance peaks. The origin of two peaks emerging at anodic and cathodic potentials is unveiled to be an electrosorption of ions and a structural phase transition, resp. We further find a cation complexation gradually modifies the EDL structure and the field strength, which linearly scales the carbon dioxide reduction activity. This study deciphers the complex structural response of the EDL and highlights its catalytic importance, which bridges the mechanistic gap between the EDL structure and electrocatalysis. In the experimental materials used by the author, we found 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5COA of Formula: C10H20O5)

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. COA of Formula: C10H20O5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem