Tag: 200-300

《Empirical Models of Stability of Crown Ether Complexes with Alkaline and Alkaline-Earth Metals in Selected Pure Solvents》 was published in Russian Journal of General Chemistry in 2020. These research results belong to Bondarev, N. V.. Product Details of 33100-27-5 The article mentions the following:

An approach to predict the stability constants of coronates from the properties of solvents, cations, and crown ethers has been developed based on exploratory and neural network methods for math. modeling of equilibrium in solutions Exploratory (factor, cluster, discriminant, canonical, decision trees), regression, and neural network (supervised and Kohonen network) models of the stability of crown ethers (12C4, 13C4, 14C4, 15C4, 15C5, 18C6, 21C7, 24C8, B12C4, B15C5, CH15C5, CH18C6, DCH18C6, DCH21C7, DB18C6, DB21C7, DB24C8, DB27C9, and DB30C10) complexes with cations of alkali (Li+, Na+, K+, Cs+, Rb+) and alk.-earth (Ca2+, Sr2+, Ba2+) metals in aqueous and non-aqueous (acetone, acetonitrile, DMSO, methanol, pyridine, DMF, dioxane, propylene carbonate, 1,2-dichloroethane, and nitrobenzene) solutions have been developed according to the properties of solvents (diameter of solvent mol., Kamlet-Taft parameter, Dimroth-Reichardt parameter, dielec. constant), crown ethers (Balaban topol. index), and cations (cation diameter) at 298.15 K.1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Product Details of 33100-27-5) was used in this study.

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Product Details of 33100-27-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《An Efficient Sequential One-Pot Approach for the Synthesis of C3-Functionalized Imidazo[1,2-a]pyridines under Transition-Metal Free Conditions》 were Reddy, Raju Jannapu; Shankar, Angothu; Kumari, Arram Haritha. And the article was published in Asian Journal of Organic Chemistry in 2019. Application of 882-33-7 The author mentioned the following in the article:

A metal-free sequential one-pot three-component protocol is described for the synthesis of C3-functionalized imidazo[1,2-a]pyridines. A successive construction of imidazo[1,2-a]pyridine I (R = 4-MeC6H4, 2-naphthyl, 2-thienyl, etc.; R1 = SMe, naphthalen-1-ylsulfanyl, pyridin-2-ylsulfanyl, etc.; X = H, 6-Br, 6-Cl, 7-Me, 8-Me) followed by iodine-catalyzed sulfenylation has been achieved in a one-pot operation from readily available α-bromomethyl ketones RC(O)CH2Br, 2-aminopyridines II and thiosulfonates R1S(O)2Ar (Ar = C6H5, 1-naphthyl, 2-thienyl, etc.). An immense array of 3-sulfenylimidazo[1,2-a]pyridines I was obtained in good to high yields. Also, the method is extended for the synthesis of C3-halogenated imidazo[1,2-a]pyridines I (R1 = Br, Cl) using sodium halides NaY in the presence of K2S2O8. Notably, the reaction between α-bromomethyl ketones and 2-aminopyridines in the presence of K2S2O8 to yields 3-bromo-2-aryl-imidazo[1,2-a]pyridines I (R1 = Br), thus implying α-bromomethyl ketones to be served as brominating agent. Overall, the present sequential one-pot protocol is straightforward, operationally simple, tolerates a broad range of functional groups, and is reliable for gram-scale experiments In the experimental materials used by the author, we found 1,2-Diphenyldisulfane(cas: 882-33-7Application of 882-33-7)

1,2-Diphenyldisulfane(cas: 882-33-7) belongs to ethers.Although ethers resist hydrolysis, they are cleaved by hydrobromic acid and hydroiodic acid. Hydrogen chloride cleaves ethers only slowly. Application of 882-33-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Journal of Organometallic Chemistry included an article by Gholivand, Khodayar; Kahnouji, Mohammad; Maghsoud, Yazdan; Hosseini, Mahdieh; Mark Roe, Stephen. Product Details of 529-28-2. The article was titled 《Synthesis, structure, computational and catalytic activities of palladium complexes containing hydrazide based amino-phosphine ligands》. The information in the text is summarized as follows:

Two new N,N-bis(diphenylphosphino)amine ligands [where amine = N-aminophthalimide (L1 = (C6H4C2NO2)N(PPh2)2) and hydrazine (L2 = (Ph2P)2NNH2)] and their Pd(II) complexes, [{(C6H4C2NO2)N(PPh2)2}PdCl2] (C1) and [PdCl2{(Ph2P)2NNH2}] (C2) were synthesized and characterized by IR and NMR spectroscopies. Single crystal x-ray diffraction techniques were used to determine the crystal structures of the complexes. The catalytic activities of mentioned complexes in Heck coupling reactions were assessed. The NBO anal. was used to study the nature of the metal-ligand interactions. In the case of L2, preparation route could produced two different products (Pro.1 and Pro.2), but only one product was prepared in high purity. To address the reason for this manner, kinetics and thermodn. of two different pathways that could led to possible products were studied theor.1-Iodo-2-methoxybenzene(cas: 529-28-2Product Details of 529-28-2) was used in this study.

1-Iodo-2-methoxybenzene(cas: 529-28-2) is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.Product Details of 529-28-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Angewandte Chemie, International Edition included an article by Aota, Yusuke; Kano, Taichi; Maruoka, Keiji. Reference of 1,4,7,10,13-Pentaoxacyclopentadecane. The article was titled 《Asymmetric Synthesis of Chiral Sulfoximines through the S-Alkylation of Sulfinamides》. The information in the text is summarized as follows:

Innovation in drug discovery critically depends on the development of new bioisosteric groups. Chiral sulfoximines, which contain a tetrasubstituted sulfur atom that bears one nitrogen, one oxygen, and two different carbon substituents, represent an emerging chiral bioisostere in medicinal chem. Chiral sulfoximines are conventionally prepared by a stereospecific nitrene transfer reaction to chiral sulfoxides; however, the number of readily available chiral sulfoxides remains limited. Herein, we report the asym. synthesis of a class of hitherto difficult-to-access chiral sulfoximines with two structurally similar alkyl chains. Our synthetic approach is based on the sulfur-selective alkylation of easily accessible chiral sulfinamides with com. available reagents under simple and safe conditions. This stereospecific S-alkylation offers a general and scalable approach to the asym. synthesis of chiral sulfoximines, which represent important substructures in bioactive mols. The experimental part of the paper was very detailed, including the reaction process of 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Reference of 1,4,7,10,13-Pentaoxacyclopentadecane)

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Reference of 1,4,7,10,13-Pentaoxacyclopentadecane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,European Journal of Organic Chemistry included an article by Casotti, Gianluca; Iuliano, Anna; Carpita, Adriano. COA of Formula: C7H7IO. The article was titled 《Arylzinc Halides by Silver Catalyzed Zinc Insertion into Aryl Iodides》. The information in the text is summarized as follows:

A catalytic amount of silver acetate efficiently promotes direct insertion of zinc metal into aryl iodides, having different structure, in ethereal solvent. Electron-rich substrates also rapidly undergo oxidative metalation. The arylzinc iodides formed give Negishi coupling products under mild reaction conditions to obtain biaryls in high yields. Sensitive functional groups like aldehydes and primary amides are well-tolerated. In the experimental materials used by the author, we found 1-Iodo-2-methoxybenzene(cas: 529-28-2COA of Formula: C7H7IO)

1-Iodo-2-methoxybenzene(cas: 529-28-2) is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.COA of Formula: C7H7IO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2014,Liu, Zhenzhen; Lin, Qiuning; Sun, Yun; Liu, Tao; Bao, Chunyan; Li, Fuyou; Zhu, Linyong published 《Spatiotemporally Controllable and Cytocompatible Approach Builds 3D Cell Culture Matrix by Photo-Uncaged-Thiol Michael Addition Reaction [Erratum to document cited in CA161:181639]》.Advanced Materials (Weinheim, Germany) published the findings.Recommanded Product: tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate The information in the text is summarized as follows:

Due to an error in the mol. structure, the macrocycles in the Table of Contents, Scheme 1, and Figure S1 were incorrect; the corrected structure is given. In the experiment, the researchers used many compounds, for example, tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6Recommanded Product: tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate)

tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6) belongs to ethers.Oxygen is more electronegative than carbon, thus the alpha hydrogens of ethers are more acidic than those of simple hydrocarbons. Recommanded Product: tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate They are far less acidic than alpha hydrogens of carbonyl groups (such as in ketones or aldehydes), however.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Cheng, Chen; Hartwig, John F. published an article on February 21 ,2014. The article was titled 《Rhodium-Catalyzed Intermolecular C-H Silylation of Arenes with High Steric Regiocontrol》, and you may find the article in Science (Washington, DC, United States).Electric Literature of C14H21BO3 The information in the text is summarized as follows:

Regioselective C-H functionalization of arenes has widespread applications in synthetic chem. The regioselectivity of these reactions is often controlled by directing groups or steric hindrance ortho to a potential reaction site. Here, authors report a catalytic intermol. C-H silylation of unactivated arenes that manifests very high regioselectivity through steric effects of substituents meta to a potential site of reactivity. The silyl moiety can be further functionalized under mild conditions but is also inert toward many common organic transformations, rendering the silylarene products useful building blocks. The remote steric effect that we observe results from the steric properties of both the rhodium catalyst and the silane. In the experiment, the researchers used 2-(4-Methoxy-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 214360-63-1Electric Literature of C14H21BO3)

2-(4-Methoxy-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 214360-63-1) belongs to ethers. Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. Electric Literature of C14H21BO3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Name: Bis(4-methoxyphenyl)amineIn 2020 ,《Doped but Stable: Spirobisacridine Hole Transporting Materials for Hysteresis-Free and Stable Perovskite Solar Cells》 was published in Journal of the American Chemical Society. The article was written by Drigo, Nikita; Roldan-Carmona, Cristina; Franckevicius, Marius; Lin, Kun-Han; Gegevicius, Rokas; Kim, Hobeom; Schouwink, Pascal A.; Sutanto, Albertus A.; Olthof, Selina; Sohail, Muhammad; Meerholz, Klaus; Gulbinas, Vidmantas; Corminboeuf, Clemence; Paek, Sanghyun; Nazeeruddin, Mohammad Khaja. The article contains the following contents:

Four spirobisacridine (SBA) hole-transporting materials were synthesized and employed in perovskite solar cells (PSCs). The mols. bear electronically inert alkyl chains of different length and bulkiness, attached to in-plane N atoms of nearly orthogonal spiro-connected acridines. Di-p-methoxyphenylamine (DMPA) substituents tailored to the central SBA-platform define electronic properties of the materials mimicking the structure of the benchmark 2,2′,7,7′-tetrakis(N,N-di-4-methoxyphenylamino)-9,9′-spirobifluorene (spiro-MeOTAD), while the alkyl pending groups affect mol. packing in thin films and affect the long-term performance of PSCs. Devices with SBA-based hole transporting layers (HTL) attain efficiencies on par with spiro-MeOTAD. More importantly, solar cells with the new HTMs are hysteresis-free and demonstrate good operational stability, despite being doped as spiro-MeOTAD. The best performing MeSBA-DMPA retained 88% of the initial efficiency after a 1000 h aging test under constant illumination. The results clearly demonstrate that SBA-based compounds are potent candidates for a design of new HTMs for PSCs with improved longevity. The experimental process involved the reaction of Bis(4-methoxyphenyl)amine(cas: 101-70-2Name: Bis(4-methoxyphenyl)amine)

Bis(4-methoxyphenyl)amine(cas: 101-70-2) is a diphenylamine derivative used as a chemical additive for cured rubber.Bis(4-methoxyphenyl)amine is highly toxic and may potentially induce chromosome abberation.Name: Bis(4-methoxyphenyl)amine

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Angewandte Chemie, International Edition included an article by Kang, Yan-Shang; Zhang, Ping; Li, Min-Yan; Chen, You-Ke; Xu, Hua-Jin; Zhao, Jing; Sun, Wei-Yin; Yu, Jin-Quan; Lu, Yi. Electric Literature of C12H10S2. The article was titled 《Ligand-Promoted RhIII-Catalyzed Thiolation of Benzamides with a Broad Disulfide Scope》. The information in the text is summarized as follows:

A ligand-promoted RhIII-catalyzed C(sp2)-H activation/thiolation of benzamides has been developed. Using bidentate mono-N-protected amino acid ligands led to the first example of RhIII-catalyzed aryl thiolation reactions directed by weakly coordinating directing amide groups. The reaction tolerates a broad range of amides and disulfide reagents. The experimental part of the paper was very detailed, including the reaction process of 1,2-Diphenyldisulfane(cas: 882-33-7Electric Literature of C12H10S2)

1,2-Diphenyldisulfane(cas: 882-33-7) belongs to ethers.Oxygen is more electronegative than carbon, thus the alpha hydrogens of ethers are more acidic than those of simple hydrocarbons. Electric Literature of C12H10S2 They are far less acidic than alpha hydrogens of carbonyl groups (such as in ketones or aldehydes), however.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Chemical Research in Chinese Universities included an article by Wang, Junzhong; Li, Hengyu; Zhang, Dongdong; Bai, Jie. Product Details of 529-28-2. The article was titled 《Amorphous Cu0 on Carbon Nanofiber as Recyclable Heterogeneous Catalyst for N-Arylation Reactions》. The information in the text is summarized as follows:

A novel heterogeneous catalyst, amorphous Cu0 on the carbon nanofibers was developed and characterized by means of several characterization techniques. The prepared Cu0 was investigated as a heterogeneous catalyst for N-arylation reaction. The results show that is an excellent catalyst with recyclability, high consistency and catalytic activity. After the catalyst was used for 5 cycles in the N-arylation reaction, amorphous Cu0 reunited into crystalline copper nanoparticles with different particle sizes and its good heterogeneity in the catalytic system was confirmed after the catalyst recovery.1-Iodo-2-methoxybenzene(cas: 529-28-2Product Details of 529-28-2) was used in this study.

1-Iodo-2-methoxybenzene(cas: 529-28-2) is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.Product Details of 529-28-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem