Tag: 200-300

In 2022,Ravuru, Shanmuk Srinivas; Jana, Animesh; De, Sirshendu published an article in Advanced Materials Interfaces. The title of the article was 《Discretization and Encapsulation of Palladium inside the Cavity of Crown Ether within the Interlayer of Layered Double Hydroxide for Enhanced Activity: A Case Study with Hydrogenation Reaction》.Electric Literature of C10H20O5 The author mentioned the following in the article:

The activity of the noble metal-based heterogeneous catalysts is limited by weak metal-support interactions, aggregation, and low surface to volume (S/V) ratio. The activity can be augmented in many ways. Among them, the discretization of the active sites and redistribution of electron d. around the metal atom is an important one. In this work, these two phenomena are studied concerning a model reaction, hydrogenation of p-nitrophenol (p-NP). Herein, 1,4,7,10,13-pentaoxacyclopentadecane ether is introduced in the basal space of layered double hydroxide (LDH) to encapsulate noble Pd0 atom inside the cavity of the crown mol. strategically. The modified LDH (Pda-ECC-L0.10@in situ CoAl LDH) augments the properties, like, high S/V ratio and nonaggregation of active sites by forming nonagglomerative discrete catalytic (DNSC) sites within the cavity of crown ether in the basal space. The developed catalyst exhibits higher turnover frequency demonstrating the improved activity due to the formed DNSC sites and redistributes electron d. around the Pd atoms by LDH layers and crown mols. Thus, the present material synthesis route can be considered as a stand-alone method for preparation of the supported sub-nanometer noble metal catalyst with higher activity and can be exploited for reactions where noble metal catalyst are used. In addition to this study using 1,4,7,10,13-Pentaoxacyclopentadecane, there are many other studies that have used 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Electric Literature of C10H20O5) was used in this study.

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Electric Literature of C10H20O5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Poly(ethylene oxide) helical conformation and alkali metal cation selectivity studied using electrospray ionization mass spectrometry》 was written by Yin, Changna; Fu, Jie; Lu, Xiuyang. Recommanded Product: 33100-27-5 And the article was included in Rapid Communications in Mass Spectrometry in 2020. The article conveys some information:

The poly(ethylene oxide) (PEO)-alkali metal cation interaction is widely used in many areas. The conformation of the PEO-alkali metal cation complex has been studied extensively, but the conformational mechanism is still unclear. Simulations have been used to explain the mechanism, but there is a lack of exptl. data from long PEO chains to verify the simulation results. The relative peak abundance of PEO (iso-C10H21(OC2H4)nOH (naverage = 7,) where n denotes the number of ethylene oxide (EO) units) oligomers complexed to five alkali metal cations (Li+, Na+, K+, Rb+ and Cs+) was studied using pos. electrospray ionization mass spectrometry (ESI-MS). The ion selectivity of PEO oligomers to alkali metal cations corresponded to the peak abundance in competitive ESI-MS. PEO formed its first helix when the number of EO units reached six and the helix played an important role in the ion selectivity of PEO. For larger PEO oligomers with a helix, the ion selectivity of PEO depended on the degree of host-guest matching of the cations and the helix. The highest selectivity of PEO to K+ was due to K+ providing the best shape matching with the helical cavity. For smaller PEO oligomers without a helix, the selectivity was mainly determined by the surface charge d. of the cations. Conclusions : The formational mechanism of the PEO-alkali metal cation complex was predicted. The results gave straightforward evidence to explain the conformational mechanism of the PEO-alkali metal cation complex and provided exptl. data for further simulation studies. In the experiment, the researchers used 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Recommanded Product: 33100-27-5)

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Recommanded Product: 33100-27-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Journal of Metals, Materials and Minerals included an article by Worlee, Anuwat; Saiwari, Sitisaiyidah; Dierkes, Wilma; Sarkawi, Siti Salina; Nakason, Charoen. Safety of 1,2-Diphenyldisulfane. The article was titled 《Influence of filler network on thermo-chemical de-vulcanization efficiency of carbon black filled natural rubber》. The information in the text is summarized as follows:

Carbon black is often used as the reinforcing filler in tires since it plays an important role in improvement of tires mech. properties such as abrasion, stiffness, modulus and fatigue life. In this study, natural rubber (NR) filled with various loadings of carbon black was prepared Then, the NR vulcanizates were de-vulcanized via thermo-chem. method using di-Ph disulfide as de-vulcanization aid. The de-vulcanization efficiency was analyzed by relationship between sol fraction and crosslink d. of the de-vulcanizates. It is found that the de-vulcanization efficiency is influenced by filler loading. This is attributed to the degree of filler network formation in a rubber matrix which is depended on the filler loadings. In the unfilled de-vulcanizates the results showed that almost 100% of sol fraction and the crosslink d. reduced to almost zero are observed Adding carbon black results in a decrease of sol fraction and increase of crosslink densities. This is due to during de-vulcanization some occurred reactive radicals reacted with active site of carbon black surfaces in filler network to form gels of complex compound Hence, the de-vulcanization efficiency is lower with increasing carbon black loadings. After reading the article, we found that the author used 1,2-Diphenyldisulfane(cas: 882-33-7Safety of 1,2-Diphenyldisulfane)

1,2-Diphenyldisulfane(cas: 882-33-7) belongs to ethers. Ethers lack the hydroxyl groups of alcohols. Safety of 1,2-Diphenyldisulfane Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2013,Lercher, Lukas; McGouran, Joanna F.; Kessler, Benedikt M.; Schofield, Christopher J.; Davis, Benjamin G. published 《DNA Modification under Mild Conditions by Suzuki-Miyaura Cross-Coupling for the Generation of Functional Probes》.Angewandte Chemie, International Edition published the findings.Formula: C9H19NO4 The information in the text is summarized as follows:

We described an efficient method for the introduction of a variety of sensitive and useful functional groups by Suzuki-Miyaura cross-coupling to halogenated pyrimidine bases. After reading the article, we found that the author used tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6Formula: C9H19NO4)

tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6) belongs to ethers.Although ethers resist hydrolysis, they are cleaved by hydrobromic acid and hydroiodic acid. Hydrogen chloride cleaves ethers only slowly. Formula: C9H19NO4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《para-C-H Borylation of benzene derivatives by a bulky iridium catalyst》 was written by Saito, Yutaro; Segawa, Yasutomo; Itami, Kenichiro. SDS of cas: 214360-63-1 And the article was included in Journal of the American Chemical Society on April 22 ,2015. The article conveys some information:

A highly para-selective aromatic C-H borylation has been accomplished. By a new iridium catalyst bearing a bulky diphosphine ligand, Xyl-MeO-BIPHEP, the C-H borylation of monosubstituted benzenes can be affected with para-selectivity up to 91%. This catalytic system is quite different from the usual iridium catalysts that cannot distinguish meta- and para-C-H bonds of monosubstituted benzene derivatives, resulting in the preferred formation of meta-products. The para-selectivity increases with increasing bulkiness of the substituent on the arene, indicating that the regioselectivity of the present reaction is primarily controlled by steric repulsion between substrate and catalyst. Caramiphen, an anticholinergic drug used in the treatment of Parkinson’s disease, was converted into five derivatives via our para-selective borylation. The present [Ir(cod)OH]2/Xyl-MeO-BIPHEP catalyst represents a unique, sterically controlled, para-selective, aromatic C-H borylation system that should find use in streamlined, predictable chem. synthesis and in the rapid discovery and optimization of pharmaceuticals and materials. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxy-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 214360-63-1SDS of cas: 214360-63-1)

2-(4-Methoxy-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 214360-63-1) belongs to ethers.Oxygen is more electronegative than carbon, thus the alpha hydrogens of ethers are more acidic than those of simple hydrocarbons. SDS of cas: 214360-63-1 They are far less acidic than alpha hydrogens of carbonyl groups (such as in ketones or aldehydes), however.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Sagane, Fumihiro; Ogi, Kenta; Konno, Akinori; Kanamura, Kiyoshi published an article in 2021. The article was titled 《The effect of the coordination ability on the Mg plating/stripping behavior in Mg(N(CF3SO2)2)2/glyme based electrolytes》, and you may find the article in Journal of the Electrochemical Society.Application of 33100-27-5 The information in the text is summarized as follows:

The effect of the coordination ability of the solvent species on the Mg plating/stripping behavior was investigated. The Mg plating reaction in Mg(N(CF3SO2)2)2/diglyme was inhibited by the equimolar of 15-crown-5 ether (15C5) to Mg2+-ion. On the other hand, Mg plating took place in the solution by reducing the amount of 15C5 less than that of Mg2+-ion. FT-IR spectra showed that 15C5 preferentially solvated Mg2+-ion in the glyme based solutions The theor. calculation indicated the interaction between Mg2+-ion and each O atom in 15C5 was stronger than that with diglyme or larger sized crown ether. The results showed that the coordination ability of the solvent species could be the critical for the Mg plating reaction. The experimental process involved the reaction of 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Application of 33100-27-5)

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Application of 33100-27-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Chalcogen Bonding of SO2 and s-Block Metal Iodides Near Room Temperature: A Remarkable Structural Diversity》 was published in European Journal of Inorganic Chemistry in 2020. These research results belong to Dankert, Fabian; Feyh, Anne; von Haenisch, Carsten. Electric Literature of C10H20O5 The article mentions the following:

In this contribution the authors have systematically explored the coordination chem. of the iodide anion towards SO2. While employing large organocations like s-block metal complexes of crown-ethers, the authors discovered a remarkable structural diversity within the herein characterized compounds together with novel architectures of SO2 solvates. The observed O2S···I- interactions are strong enough to determine the crystal packing and dimensionality. In the light of chalcogen bonding, the small mol. SO2 is introduced as a supramol. synthon. In the light of a chem. in non-aqueous solutions, the ISO2- anion is revisited. Chalcogen bonding was established to form one-dimensional networks in the compounds [Li([12]crown-4)H2O]I·SO2 (1), [Na([15]crown-5)(SO2)I] (2), [K([18]crown-6)(SO2)I] (4), [NH4([18]crown-6)]I·SO2 (5), [Rb([18]crown-6)I(SO2)]·2SO2 (6) and [Cs([18]crown-6)(SO2)2I] (7) all of which were obtained by 1:1 complexation of the resp. iodide salt and resp. crown-ether in SO2 solution Two-dimensional networks were obtained within the alk. earth metal compounds [Mg([12]crown-4)2]I2·4SO2 (9) and [Ba2([18]crown-6)2(SO2I)(SO2)2I3]·SO2 (11). The iodosulfite ion ISO2- was obtained either by shielding Na+ ions with [12]crown-4, conversion of MgI2 with [15]crown-5, conversion of CaI2 with [18]crown-6 or conversion of BaI2 with [18]crown-6 (11, as aforementioned). [Na([12]crown-4)2]ISO2 (3), [Mg([15]crown-5)(ISO2)2] (8) and [Ca2([18]crown-6)(SO2I)3]I3 (10) were characterized. In these resp. compounds the S···I atom distances are considerably shorter than those previously reported. Exptl. data around the chem. of halosulfites is provided. Besides network structures and the iodosulfite formation, an SO2-rich aggregate could be observed An SO2 adduct of the composition [I2(SO2)5]2- is present in [Na([12]crown-4)2]I·2.75SO2 (3a). After reading the article, we found that the author used 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Electric Literature of C10H20O5)

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Electric Literature of C10H20O5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Angewandte Chemie, International Edition included an article by Pitts, Cody Ross; Bornemann, Dustin; Liebing, Phil; Santschi, Nico; Togni, Antonio. Quality Control of 1,2-Diphenyldisulfane. The article was titled 《Making the SF5 Group More Accessible: A Gas-Reagent-Free Approach to Aryl Tetrafluoro-λ6-sulfanyl Chlorides》. The information in the text is summarized as follows:

A series of aryl tetrafluoro-λ6-sulfanyl chlorides R-X [R = Ph, 4-BzOC6H4, 5-Br-2-pyridyl, 5-Br-2-pyrimidinyl, etc.; X = SF4Cl] was synthesized via trifluoroacetic acid catalyzed gas-reagent-free oxidative polyfluorination of aryl disulfides. This approach overcame the reliance on hazardous fluorinating reagents and/or gas reagents (e.g. Cl2) by employing easy-to-handle trichloroisocyanuric acid, potassium fluoride and catalytic amounts of acid. Furthermore, the same approach provided an access to compounds R-X [X = SF3, SF5, SeF3] which extended the applications of this chem. beyond arene SF5-functionalization and demonstrated its ability to address a more general oxidative fluorination problem. In the experiment, the researchers used many compounds, for example, 1,2-Diphenyldisulfane(cas: 882-33-7Quality Control of 1,2-Diphenyldisulfane)

1,2-Diphenyldisulfane(cas: 882-33-7) belongs to ethers.The C-O bonds that comprise simple ethers are strong. Quality Control of 1,2-Diphenyldisulfane They are unreactive toward all but the strongest bases. Although generally of low chemical reactivity, they are more reactive than alkanes.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Borylation of Unactivated Aryl Chlorides under Mild Conditions by Using Diisopropylaminoborane as a Borylating Reagent》 was written by Guerrand, Helene D. S.; Marciasini, Ludovic D.; Jousseaume, Melissa; Vaultier, Michel; Pucheault, Mathieu. Synthetic Route of C14H21BO3 And the article was included in Chemistry – A European Journal in 2014. The article conveys some information:

The synthesis of arylboronic ester derivatives from aryl chlorides by using aryl(amino)boranes is described. Palladium-catalyzed coupling between aryl chlorides and diisopropylaminoborane leads to the formation of a C-B bond under mild conditions. A wide range of functional groups are tolerated, making this method particularly useful for the borylation of functionalized aromatics In the experiment, the researchers used many compounds, for example, 2-(4-Methoxy-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 214360-63-1Synthetic Route of C14H21BO3)

2-(4-Methoxy-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(cas: 214360-63-1) belongs to ethers.Ethers do have nonbonding electron pairs on their oxygen atoms, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Synthetic Route of C14H21BO3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Macropinocytosis as a key determinant of peptidomimetic uptake in cancer cells》 was written by Yoo, Daniel Y.; Barros, Stephanie A.; Brown, Gordon C.; Rabot, Christian; Bar-Sagi, Dafna; Arora, Paramjit S.. Recommanded Product: tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate And the article was included in Journal of the American Chemical Society in 2020. The article conveys some information:

Peptides and peptidomimetics represent the middle space between small mols. and large proteins-they retain the relatively small size and synthetic accessibility of small mols. while providing high binding specificity for biomol. partners typically observed with proteins. During the course of our efforts to target intracellular protein-protein interactions in cancer, we observed that the cellular uptake of peptides is critically determined by the cell line-specifically, we noted that peptides show better uptake in cancer cells with enhanced macropinocytic indexes. Here, we describe the results of our anal. of cellular penetration by different classes of conformationally stabilized peptides. We tested the uptake of linear peptides, peptide macrocycles, stabilized helixes, β-hairpin peptides, and cross-linked helix dimers in 11 different cell lines. Efficient uptake of these conformationally defined constructs directly correlated with the macropinocytic activity of each cell line: high uptake of compounds was observed in cells with mutations in certain signaling pathways. Significantly, the study shows that constrained peptides follow the same uptake mechanism as proteins in macropinocytic cells, but unlike proteins, peptide mimics can be readily designed to resist denaturation and proteolytic degradation Our findings expand the current understanding of cellular uptake in cancer cells by designed peptidomimetics and suggest that cancer cells with certain mutations are suitable mediums for the study of biol. pathways with peptide leads. The experimental part of the paper was very detailed, including the reaction process of tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6Recommanded Product: tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate)

tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6) belongs to ethers.The C-O bonds that comprise simple ethers are strong. Recommanded Product: tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate They are unreactive toward all but the strongest bases. Although generally of low chemical reactivity, they are more reactive than alkanes.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem