Tag: 200-300

Synthesis, complexation, and fluorescence behavior of 3,4-dimethylthieno[2,3-b]thiophene carrying two monoaza-15-crown-5 ether groups was written by Wu, Yong-Xiang;Cao, Jing;Deng, Hai-Yan;Feng, Jun-Xiang. And the article was included in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy in 2011.COA of Formula: C10H21NO4 This article mentions the following:

A novel fluoroionophore I based on 3,4-dimethylthieno[2,3-b]thiophene bearing two monoaza-15-crown-5 ethers at the 3- and 4-positions was prepared UV-vis and fluorescence responses of compound I upon the addition of alkali and alk. earth metal cations were evaluated in acetonitrile solution Receptor I showed a unique response for Ba²⁺ due to the formation of an intramol. sandwich complex. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3COA of Formula: C10H21NO4).

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).COA of Formula: C10H21NO4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Stereoselective synthesis of 3,4-trans-disubstituted γ-lactams by cerium(IV) ammonium nitrate mediated radical cyclization of cinnamamides was written by Nair, Vijay;Mohanan, Kishor;Suja, Tachapully D.;Biju, Akkattu T.. And the article was included in Synthesis in 2007.Safety of 3-(2,4-Dimethoxyphenyl)acrylic acid This article mentions the following:

A facile synthesis of 3,4-trans-disubstituted γ-lactams, e.g., I, was developed, consisting of the radical cyclization of cinnamamides mediated by cerium(IV) ammonium nitrate. The single-electron-transfer reaction of the methoxystyrenyl moiety mediated by cerium(IV) ammonium nitrate gives rise to a cation radical, whose cyclization followed by reaction with oxygen and methanol generates 3,4-trans-disubstituted γ-lactams. In the experiment, the researchers used many compounds, for example, 3-(2,4-Dimethoxyphenyl)acrylic acid (cas: 6972-61-8Safety of 3-(2,4-Dimethoxyphenyl)acrylic acid).

3-(2,4-Dimethoxyphenyl)acrylic acid (cas: 6972-61-8) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Safety of 3-(2,4-Dimethoxyphenyl)acrylic acid

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Covalently decorated crown ethers on magnetic graphene oxides as bi-functional adsorbents with tailorable ion recognition properties for selective metal ion capture in water was written by Nisola, Grace M.;Parohinog, Khino J.;Cho, Min Kyung;Burnea, Francis Kirby B.;Lee, Jin Yong;Seo, Jeong Gil;Lee, Seong-Poong;Chung, Wook-Jin. And the article was included in Chemical Engineering Journal (Amsterdam, Netherlands) in 2020.Recommanded Product: 1,4,7,10-Tetraoxa-13-azacyclopentadecane This article mentions the following:

Metal ions (Mⁿ⁺) in water are considered as environmental pollutants, as industrial impurities or as potential secondary sources for valuable metals. Increasing generation of complex feed streams has raised the need for more specialized adsorbents that could preferentially capture the target Mⁿ⁺. While graphene oxide (GO) is an effective adsorbent, its indiscriminate sequestration neg. affects its selectivity. To meet the growing demand for more Mⁿ⁺-selective materials, GO adsorbents with dual features of ion recognition and magnetic responsiveness were developed. The bi-functional GOs were fabricated by in-situ nucleation of Fe₃O₄ nanoclusters on GO oxygenous groups and by direct grafting of ethynylbenzene linkers on its backbone, which served as tethering sites for the macrocyclic crown ether (CEs) ligands with tunable Mⁿ⁺ affinities (i.e. CE@Fe₃O₄-rGO). As proof-of-concept, 12CE4@Fe₃O₄-rGO was proven highly selective for Li⁺ capture, achieving α = 367-14,513 against Na⁺, K⁺, Mg²⁺, Ca²⁺ in seawater. Its Langmuir-type Li⁺ adsorption achieved nearly âˆ?00% 12CE4 utilization (1.03 mmol g^-1 CE loading). Its pseudo-second uptake rate demonstrated its rapid Li⁺ capture. 12CE4@Fe₃O₄-rGO is water-dispersible, magnetically retrievable, and recyclable with consistent Li⁺ uptake performance. By replacing the CEs with aza15CE5, aza18CE6 and dibenzo-24CE8, three more types of CE@Fe₃O₄-rGOs (1.24-1.71 mmol CE g^-1) were successfully synthesized with varying affinities towards heavy metals, radionuclides and alkali metal ions. These findings highlight the versatility of the proposed technique in producing a wide selection of CE@Fe₃O₄-rGOs which can be used for selective Mⁿ⁺ capture in various application for water decontamination, salts removal, and resource recovery. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3Recommanded Product: 1,4,7,10-Tetraoxa-13-azacyclopentadecane).

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Recommanded Product: 1,4,7,10-Tetraoxa-13-azacyclopentadecane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Metal-Free Oxidative para Cross-Coupling of Phenols was written by Morimoto, Koji;Sakamoto, Kazuma;Ohnishi, Yusuke;Miyamoto, Takeshi;Ito, Motoki;Dohi, Toshifumi;Kita, Yasuyuki. And the article was included in Chemistry – A European Journal in 2013.Application In Synthesis of 2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane This article mentions the following:

A broadly applicable oxidative cross-coupling reaction of phenols (at the para position) with various arenes is described to obtain biaryls, e.g., I. This versatile hypervalent-iodine(III)-induced oxidative coupling operates under mild reaction conditions without the use of expensive catalysts, and tolerates a diverse range of the arene coupling partners. As the phenol rapidly interacts with the iodine reagent, homo-coupling of the starting materials and over-oxidation of the coupling products are avoided. The reaction has the addnl. benefit of being free of metal catalysts and not requiring prefunctionalization of the starting materials. In the experiment, the researchers used many compounds, for example, 2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 365564-07-4Application In Synthesis of 2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane).

2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 365564-07-4) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Application In Synthesis of 2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Enantioselective Copper-Catalyzed Formal [2+1] and [4+1] Annulations of Diynes with Ketones via Carbonyl Ylides was written by Qi, Lin-Jun;Li, Cui-Ting;Huang, Zheng-Qi;Jiang, Jia-Tian;Zhu, Xin-Qi;Lu, Xin;Ye, Long-Wu. And the article was included in Angewandte Chemie, International Edition in 2022.Application In Synthesis of 4-Iodo-1-methoxy-2-methylbenzene This article mentions the following:

Carbonyl ylides have proven to be powerful synthons for the efficient construction of various valuable O-heterocycles, and the formation of carbonyl ylides by the reaction of metal carbenes with carbonyls has attracted increasing attention over the past decades. However, a catalyst-controlled highly enantioselective reaction of carbonyl ylides from metal carbenes is extremely challenging. Herein, a novel copper-catalyzed asym. formal [2+1] and [4+1] annulations of diynes with ketones via carbonyl ylides is reported. Importantly, this protocol not only represents the first example of successful asym. epoxidation via carbonyl ylides, but also constitutes the first reaction of vinyl cations with carbonyl compounds This method leads to the divergent, practical and atom-economical synthesis of a range of chiral oxiranes and dihydrofurans in moderate to excellent yields with generally excellent enantioselectivities and diastereoselectivities via remote-stereocontrol strategy. In the experiment, the researchers used many compounds, for example, 4-Iodo-1-methoxy-2-methylbenzene (cas: 75581-11-2Application In Synthesis of 4-Iodo-1-methoxy-2-methylbenzene).

4-Iodo-1-methoxy-2-methylbenzene (cas: 75581-11-2) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Application In Synthesis of 4-Iodo-1-methoxy-2-methylbenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

GC/MS, HPLC and FAB mass spectrometric analysis of organic micropollutants in Barcelona’s water supply was written by Rivera, Josep;Ventura Josep;Caixach, Josep;De Torres, Mariona;Figueras, Albert. And the article was included in International Journal of Environmental Analytical Chemistry in 1987.Application In Synthesis of 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol This article mentions the following:

Water samples from the Llobregat River entering 2 water work plants, Barcelona tap water, and waste dumping samples taken along the river course were analyzed for trace organic contaminants by different procedures, liquid-liquid extraction, adsorption on granular activated C followed by gas chromatog./mass spectrometry (GC/MS). Ether-insoluble organic fractions were analyzed and fractionated by HPLC with diode-array detection, followed by fast-atom bombardment (FAB) and fast-atom bombardment-collision induced dissociation-MIKES characterization. The results, after 2 yrs of monitoring, proved that surfactants, plasticizers, ethylene glycol derivatives, phosphates, hydrocarbons, and other miscellaneous compounds are considered chronic pollutants of the Llobregat River. Some of the compounds identified by GC/MS and FAB mass spectrometry have not been previously reported to occur in water. In the experiment, the researchers used many compounds, for example, 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol (cas: 20324-33-8Application In Synthesis of 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol).

1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol (cas: 20324-33-8) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Application In Synthesis of 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Bifunctional Cinchona Alkaloid Thiourea Catalyzed Highly Efficient, Enantioselective Aza-Henry Reaction of Cyclic Trifluoromethyl Ketimines: Synthesis of Anti-HIV Drug DPC 083 was written by Xie, Hexin;Zhang, Yinan;Zhang, Shilei;Chen, Xiaobei;Wang, Wei. And the article was included in Angewandte Chemie, International Edition in 2011.Reference of 56619-93-3 This article mentions the following:

A novel highly efficient bifunctional cinchona alkaloid thiourea catalyzed enantioselective aza-Henry reaction of trifluoromethylquinazolinones with nitromethanes is reported. The reaction provides enantioenriched trifluoromethyl nitromethyl dihydroquinazolinones in good yields and enantioselectivities. In the experiment, the researchers used many compounds, for example, N-(3-Methoxyphenyl)pivalamide (cas: 56619-93-3Reference of 56619-93-3).

N-(3-Methoxyphenyl)pivalamide (cas: 56619-93-3) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Reference of 56619-93-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Phosphorus-nitrogen compounds: Part 61. The novel sodium complexes of monoferrocenylspirocyclotriphosphaza-crown ethers was written by Uzunalioglu, Nese;Asmafiliz, Nuran;Kilic, Zeynel;Hokelek, Tuncer. And the article was included in Inorganica Chimica Acta in 2022.Application of 66943-05-3 This article mentions the following:

Condensation reactions of hexachlorocyclotriphosphazene, N₃P₃Cl₆ (HCCP, trimer) and four different diamines (1–4) yielded tetrachloromono (5, 7 and 8) and bisferrocenyl (6) spirocyclotriphosphazenes. Reactions of 5, 7 and 8 with two equimolar amounts of 1-aza-15-crown-5 ether (L) produced new monoferrocenylspirocyclotriphosphazabis(crown ethers) (9, 10 and 12) in THF, resp. The only monoferrocenylspirocyclotriphosphazatris(crown ether) (13) was obtained from the reaction of 8 with three equimolar amounts of L. However, reactions of 7 and 8 with four equimolar amounts of L gave monoferrocenylspirocyclotriphosphaza-tetrakis(crown ethers) 11 and 14. In addition, the complexation reactions of ditopic phosphaza-crown ethers (9, 10 and 11) with NaClO₄ yielded novel mononuclear sandwich-type sodium complexes (9a, 10a and 11a). Tri- and tetranuclear complexes (13a and 14a) were obtained as a result of the complexation reactions of tri- and tetratopic phosphaza-crown ethers (13 and 14) with NaClO₄. Characterizations of phosphaza-crown ethers and complexes were performed using elemental anal., mass spectrometry, FTIR, and ¹H, ¹³C and ³¹P NMR techniques. Ditopic phosphazenes (9, 10 and 12) and complexes (9a, 10a and 11a) have a stereogenic P center. While the tritopic ligand (13) and complex (13a) have two stereogenic P centers. They are expected to be in racemic mixtures In addition, crystal structures of phosphazenes 6 and 9 were elucidated using x-ray crystallog. The absolute configurations of the enantiomers of 9 were determined as R and S. Furthermore, intermol. interactions in crystal structures of 6 and 9 were determined by Hirshfeld surface (HS) anal. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3Application of 66943-05-3).

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Application of 66943-05-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis and crystal structure of new bis(azacrown ethers) on the basis of 1,2-bis(2,2,2-trichloro-1-isocyanatoethoxy)benzene was written by Luk’yanenko, Nickolay G.;Pastushok, Viktor N.;Lyapunov, Alexander Yu.;Onys’ko, Pyotr P.;Sinitsa, Anatoliy D.;Povolotskiy, Mark I.;Zubatyuk, Roman I.;Shiskhin, Oleg V.. And the article was included in Makrogeterotsikly in 2009.Computed Properties of C10H21NO4 This article mentions the following:

Synthesis, properties and X-Ray anal. of the new bis(azacrown ethers), containing bridging urea fragments are reported here. These substances have in their mol. structure both centers of anion linking (proton donating NH groups) and centers of cation linking (crown ether units) and thus may be considered as potential ion-pair receptors. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3Computed Properties of C10H21NO4).

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Computed Properties of C10H21NO4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Resorcinarenes and aza-crowns as new extractants for the separation of technetium-99 was written by Paviet-Hartmann, Patricia;Horkley, Jared;Pak, Joshua;Brown, Eric;Todd, Terry. And the article was included in Materials Research Society Symposium Proceedings in 2008.Formula: C10H21NO4 This article mentions the following:

Among the radionuclides considered for separation within the UREX + concept is Technetium-99, a uranium fission product with a low energy beta emission and a half life of 2.13 × 10⁵ years. The fission products, present in the high level waste (HLW) issued from the PUREX process, are mainly responsible for the long term radiotoxicity of this HLW stream. Partitioning and transmutation as a means of reducing the burden on a geol. repository requires Tc-99 to be removed from the HLW (partitioning) and then fragmented by fission (transmutation), which allows reduction of the radiotoxicity inventory of the remaining waste. As an example, a single isotopic species (Tc-99) can be transmuted by single neutron capture into the stable noble metal ruthenium (Ru-100). Selective extraction of Tc-99 needs to be investigated. We describe herein the synthesis of new macro-compounds which can be functionalized with oxygen, sulfur, and nitrogen donating functional groups with various cavity sizes and/or bonding modes, and the assessment of their extraction properties towards Tc-99. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3Formula: C10H21NO4).

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Formula: C10H21NO4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem