Month: October 2022

Kakinuma, Shohei; Shirota, Hideaki published the artcile< Femtosecond Raman-Induced Kerr Effect Study of Temperature-Dependent Intermolecular Dynamics in Pyrrolidinium-Based Ionic Liquids: Effects of Anion Species>, HPLC of Formula: 6482-24-2, the main research area is pyrrolidinium ionic liquid intermol dynamics anion RIKES.

We investigated the temperature dependence of the intermol. vibrational dynamics of pyrrolidinium-based ionic liquids (ILs) with 10 different anion species using femtosecond Raman-induced Kerr effect spectroscopy. The features of the temperature-dependent vibrational spectra vary with the different anions. In the case of the ILs with spherical top anions, such as tetrafluoroborate and hexafluorophosphate, and trifluoromethanesulfonate, the spectral intensity in the low-frequency region below 50 cm-1 increases with rising temperature, while that in the high-frequency region above 50 cm-1 remains almost unchanged. Similar temperature-dependent features were also found in the bis(fluorosulfonyl)amide and bis(perfluoroalkylsulfonyl)amide salts. However, the difference spectra at resp. temperature relative to 293 K indicate that the spectra of the bis(fluorosulfonyl)amide and bis(perfluoroalkylsulfonyl)amide salts are more temperature-sensitive in the low-frequency region below 50 cm-1 compared to those of the tetrafluoroborate, hexafluorophosphate, and trifluoromethanesulfonate salts. The spectra of 1-butyl-1-methylpyrrolidinium-based ILs with dicyanamide and tricyanomethide anions show a characteristic temperature dependence; in addition to an increase of the spectral intensity in the low-frequency region below 50 cm-1, a red shift of the spectra in the high-frequency side above 50 cm-1 was observed with increasing temperature This implies that the librational motions of planar dicyanamide and tricyanomethide anions contribute substantially to the low-frequency spectra. We also compared the temperature-dependent low-frequency spectra of 1-butyl-1-methylpyrrolidinium- and 1-(2-methoxyethyl)-1-methylpyrrolidinium-based ILs with some anions. Although the spectral shapes are slightly different in the range of 70-150 cm-1, which can be attributed to the intramol. vibrational modes of the cations, the temperature dependence of the spectral shapes is quite similar, indicating that the ether substitution in the cation side groups has little effects on the temperature dependence of the low-frequency spectra. The fragilities of the ILs were also estimated from the temperature-dependent viscosities and the glass-transition temperatures The fragility parameter seems to be correlated with the temperature dependence of the first moment of the low-frequency spectral bands mainly arising from the intermol. vibrations of the ILs.

Journal of Physical Chemistry B published new progress about Anions. 6482-24-2 belongs to class ethers-buliding-blocks, and the molecular formula is C3H7BrO, HPLC of Formula: 6482-24-2.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Xiao, Peihong; Tang, Zhixing; Wang, Kai; Chen, Hua; Guo, Qianyou; Chu, Yang; Gao, Lu; Song, Zhenlei published the artcile< Chemoselective Reduction of Sterically Demanding N,N-Diisopropylamides to Aldehydes>, HPLC of Formula: 56724-03-9, the main research area is aldehyde preparation sterically demanding diisopropylamide chemoselective reduction.

A sequential one-pot process for chemoselectively reducing sterically demanding N,N-diisopropylamides to aldehydes has been developed. In this reaction, amides are activated with EtOTf to form imidates, which are reduced with LiAlH(OR)3 [R = t-Bu, Et] to give aldehydes by hydrolysis of the resulting hemiaminals. The non-nucleophilic base 2,6-DTBMP remarkably improves reaction efficiency. The combination of EtOTf/2,6-DTBMP and LiAlH(O-t-Bu)3 was found to be optimal for reducing alkyl, alkenyl, alkynyl, and 2-monosubstituted aryl N,N-diisopropylamides. In contrast, EtOTf and LiAlH(OEt)3 in the absence of base were found to be optimal for reducing extremely sterically demanding 2,6-disubstituted N,N-diisopropylbenzamides. The reaction tolerates various reducible functional groups, including aldehyde and ketone. 1H NMR studies confirmed the formation of imidates stable in water. The synthetic usefulness of this methodol. was demonstrated with N,N-diisopropylamide-directed ortho-metalation and C-H bond activation.

Journal of Organic Chemistry published new progress about Aldehydes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 56724-03-9 belongs to class ethers-buliding-blocks, and the molecular formula is C9H10O2, HPLC of Formula: 56724-03-9.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Gao, Xinpei; Mariani, Alessandro; Jeong, Sangsik; Liu, Xu; Dou, Xinwei; Ding, Markus; Moretti, Arianna; Passerini, Stefano published the artcile< Prototype rechargeable magnesium batteries using ionic liquid electrolytes>, Formula: C3H7BrO, the main research area is magnesium ion speciation deposition dissolution process magnesium battery electrolyte; rechargeable magnesium battery ionic liquid electrolyte coordination sphere.

Understanding Mg-ion speciation is of utmost importance to the rational design of electrolytes for rechargeable magnesium batteries. Herein, we report an effort to better understand Mg-ion speciation in ionic liquid (IL) electrolytes through the design of alkoxy-functionalized cations with different alkoxy substituent. In contrast with previous studies focusing on the coordination sphere of Mg2+, the comparison of Raman spectroscopy, electrochem. and DFT calculation results of various IL-based electrolytes suggests that the coordination sphere of transient Mg+ plays a key role in Mg reversible deposition/dissolution process. Finally, a prototype Mg/V2O5 cell using the noncorrosive IL-based electrolyte is demonstrated for the first time, exhibiting a remarkable initial discharge capacity of 140 mAh g-1 and reversible capacity of 100 mAh g-1.

Journal of Power Sources published new progress about Battery electrolytes. 6482-24-2 belongs to class ethers-buliding-blocks, and the molecular formula is C3H7BrO, Formula: C3H7BrO.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Poon, Kevin W. C.; Dudley, Gregory B. published the artcile< Mix-and-Heat Benzylation of Alcohols Using a Bench-Stable Pyridinium Salt>, Recommanded Product: 4-(4-Methoxyphenyl)-1-butanol, the main research area is alc benzylation pyridinium triflate; ether benzyl preparation.

2-Benzyloxy-1-methylpyridinium triflate (I) is a stable, neutral organic salt that converts alcs. into benzyl ethers upon warming. The synthesis and reactivity of I are described herein. Benzylation of a wide range of alcs. occurs in good to excellent yields.

Journal of Organic Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 52244-70-9 belongs to class ethers-buliding-blocks, and the molecular formula is C11H16O2, Recommanded Product: 4-(4-Methoxyphenyl)-1-butanol.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Hansen, N. C. published the artcile< Monoalkylsulfamyl chlorides>, Electric Literature of 10305-42-7, the main research area is .

Normal C2-5 amine hydrochlorides were treated with excess SO2Cl2 18 hrs. on a water bath at 75°. In some cases more SO2Cl2 was added. The resulting oil was treated with dry ether, the precipitated amine hydrochloride filtered off, and the filtrate distilled in vacuo to give monoalkylsulfamyl chlorides, RNHSO2Cl (I). [RNH2.HCl (R given), amount added, and recovered (g.), volume (ml.) SO2Cl2 used, % yield of corresponding I (based on RNH2.HCl used) and b.p. (redistilled samples) given]: Et, 52, 23, 105 (a further 100 ml. was added after 4 hrs. reflux), 42, b0.05 52; Pr, 52, 26, 350, 13, b0.2 78°; Bu, 77, 27, 450, 39, b0.11 80°; and Am, 19, 12, 150, 8, b0.15 95°. When HCl salts of methyl-, hexyl-, cyclohexyl-, and octylamine were used, the yields of the corresponding I were too low to permit their isolation. That at least MeNHSO2Cl was formed could be concluded from the fact that MeNHSO2NHPr, m. 57-8° (ether-petr. ether), could be obtained when the impure product was treated with PrNH2. EtNHSO2NHBu, m. 73-5° (hexane), was similarly obtained from EtNHSO2Cl.

Acta Chemica Scandinavica published new progress about NMR (nuclear magnetic resonance). 10305-42-7 belongs to class ethers-buliding-blocks, and the molecular formula is C3H8ClNO2S, Electric Literature of 10305-42-7.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Shalini, Sorout; Matzger, Adam J. published the artcile< Ethylene oxide functionalization enhances the ionic conductivity of a MOF>, Category: ethers-buliding-blocks, the main research area is ethylene oxide ionic conductivity functionalization.

Varying the degree of ethylene oxide (EO) functionalization of the zirconium MOF UiO-68 affords two novel MOFs; UiO-68-EO and UiO-68-2EO exhibit solvent-free ionic conductivity upon loading LiTFSI in their pores. Incorporating EO chains provides a pathway for lithium ion migration between the coordinated sites and results in an ionic conductivity of 3.8 x 10-7 S cm-1 and 3.9 x 10-4 S cm-1 at 90 °C for UiO-68-EO/LiTFSI and UiO-68-2EO/LiTFSI resp.

Chemical Communications (Cambridge, United Kingdom) published new progress about Differential scanning calorimetry. 6482-24-2 belongs to class ethers-buliding-blocks, and the molecular formula is C3H7BrO, Category: ethers-buliding-blocks.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Tian, Ya-Ming; Guo, Xiao-Ning; Krummenacher, Ivo; Wu, Zhu; Nitsch, Joern; Braunschweig, Holger; Radius, Udo; Marder, Todd B. published the artcile< Visible-Light-Induced Ni-Catalyzed Radical Borylation of Chloroarenes>, Product Details of C13H19BO3, the main research area is chloro nickel carbene preparation catalyzed radical borylation chloroarene; crystal structure imidazolylidene nickel chloride; mol structure imidazolylidene nickel chloride; arylborane preparation.

A highly selective and general photoinduced C-Cl borylation protocol that employs [Ni(IMes)2] (IMes = 1,3-dimesitylimidazoline-2-ylidene) for the radical borylation of chloroarenes is reported. This photoinduced system operates with visible light (400 nm) and achieves borylation of a wide range of chloroarenes with B2pin2 at room temperature in excellent yields and with high selectivity, thereby demonstrating its broad utility and functional group tolerance. Mechanistic studies suggest that the borylation reactions proceed via a radical process. EPR studies demonstrate that [Ni(IMes)2] undergoes very fast Cl atom abstraction from aryl chlorides to give [Ni(I)(IMes)2Cl] and aryl radicals. Control experiments indicate that light promotes the reaction of [Ni(I)(IMes)2Cl] with aryl chlorides generating addnl. aryl radicals and [Ni(II)(IMes)2Cl2]. The aryl radicals react with an anionic sp2-sp3 diborane [B2pin2(OMe)]- formed from B2pin2 and KOMe to yield the corresponding borylation product and the [Bpin(OMe)]•- radical anion, which reduces [Ni(II)(IMes)2Cl2] under irradiation to regenerate [Ni(I)(IMes)2Cl] and [Ni(IMes)2] for the next catalytic cycle.

Journal of the American Chemical Society published new progress about Aryl chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 190788-60-4 belongs to class ethers-buliding-blocks, and the molecular formula is C13H19BO3, Product Details of C13H19BO3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Zhang, Liang; Kong, Xiangjin; Liu, Shuya; Zhao, Zhiguo; Yu, Qun; Wang, Wei; Wang, Yao published the artcile< Succinimide-Promoted Malonylamination of Alkenes with Amines and Iodonium Ylides via Trapping of Transient Aminium Radical Cations>, Synthetic Route of 10541-78-3, the main research area is succinimide promoted malonylamination alkene amine iodonium ylide.

A conceptually distinct strategy enabling malonylamination of alkenes with abundant amines and iodonium ylides without assistance of any transition metal was developed. Succinimide was identified as a proton shuttle that can not only largely accelerate the process of trapping highly unstable radical ion pairs with alkenes but also significantly improve the chem. yields.

Organic Letters published new progress about Addition reaction (carboamination). 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Synthetic Route of 10541-78-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Jiang, Lei; Guo, Fang; Wang, Yinran; Jiang, Jialin; Duan, Yangzhi; Hou, Zhaomin published the artcile< Selective N-Monomethylation of Anilines with Methanol Catalyzed by Commercial Pd/C as an Efficient and Reusable Catalyst>, Application of C8H11NO, the main research area is monomethyl aniline preparation chemoselective; amine aryl methanol palladium catalyst chemoselective methylation.

In this paper, the N-monomethylation of aniline derivatives using Pd/C catalyst and methanol as the methylation reagent was investigated. The N-monomethylation of various aryl amines was achieved with high activity and selectivity under relatively mild reaction conditions, and the yield of N-monomethyl anilines ArNHMe [Ar = Ph, 4-pyridyl, 2-MeC6H4, etc.] was over 90 %. Notably, the com., readily available, and inexpensive heterogeneous catalyst, Pd/C, could be easily recovered and reused more than five times with only a slight decrease in activity; gram-scale experiments were also successfully performed.

Asian Journal of Organic Chemistry published new progress about Aromatic amines Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Application of C8H11NO.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Sparey, Tim; Beher, Dirk; Best, Jonathan; Biba, Mirlinda; Castro, Jose L.; Clarke, Earl; Hannam, Joanne; Harrison, Timothy; Lewis, Huw; Madin, Andrew; Shearman, Mark; Sohal, Bindi; Tsou, Nancy; Welch, Christopher; Wrigley, Jonathan published the artcile< Cyclic sulfamide γ-secretase inhibitors>, Product Details of C3H8ClNO2S, the main research area is cyclic sulfamide derivative preparation gamma secretase inhibitor.

A novel series of N-alkyl-substituted cyclic sulfamides were developed from a screening hit. Chemistries were developed which allowed surveys of N-alkyl groups and amines resulting in the identification of N-trifluoroethyl-substituted cyclic sulfamides with good in vitro and in vivo γ-secretase activity. One compound with subnanomolar activity elicited a reduction in brain Aβ40 after oral dosing in APP-YAC mice.

Bioorganic & Medicinal Chemistry Letters published new progress about Alzheimer disease. 10305-42-7 belongs to class ethers-buliding-blocks, and the molecular formula is C3H8ClNO2S, Product Details of C3H8ClNO2S.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem