Jiang, Lei; Guo, Fang; Wang, Yinran; Jiang, Jialin; Duan, Yangzhi; Hou, Zhaomin published the artcile< Selective N-Monomethylation of Anilines with Methanol Catalyzed by Commercial Pd/C as an Efficient and Reusable Catalyst>, Application of C8H11NO, the main research area is monomethyl aniline preparation chemoselective; amine aryl methanol palladium catalyst chemoselective methylation.
In this paper, the N-monomethylation of aniline derivatives using Pd/C catalyst and methanol as the methylation reagent was investigated. The N-monomethylation of various aryl amines was achieved with high activity and selectivity under relatively mild reaction conditions, and the yield of N-monomethyl anilines ArNHMe [Ar = Ph, 4-pyridyl, 2-MeC6H4, etc.] was over 90 %. Notably, the com., readily available, and inexpensive heterogeneous catalyst, Pd/C, could be easily recovered and reused more than five times with only a slight decrease in activity; gram-scale experiments were also successfully performed.
Asian Journal of Organic Chemistry published new progress about Aromatic amines Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Application of C8H11NO.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem