Category: 33171-05-0

Promising Antiviral Molecules from Ayurvedic Herbs and Spices against COVID-19 was written by Rajan, Mariappan;Gupta, Prashant;Kumar, Awanish. And the article was included in Chinese Journal of Integrative Medicine in 2021.Synthetic Route of C19H16O4 The following contents are mentioned in the article:

COVID-19 is caused by the novel coronavirus severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and smashed our society severely. This has also drawn the attention of the scientific community to Ayurveda where traditional knowledge of this domain can be explored for finding COVID-19 a cure or prevention. This article aims to provide the readers an understanding of the basic principles of ancient medicine and conjugation of in silico technol. in Ayurveda for the development of core concepts of Ayurveda. The reported result in this article is an Ayurveda phytoconstituents in silico efforts study which further necessitates the need for pre-clin. and clin. research of the active compounds to increase the understanding in the development of effective future therapeutics in Ayurveda. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Synthetic Route of C19H16O4).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Synthetic Route of C19H16O4

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Quantification of bisacurone and curcuminoids in turmeric products by liquid chromatography coupled with tandem mass spectrometry was written by Miyazawa, Taiki;Higuchi, Ohki;Sasaki, Masato;Thi, Minh Tu Nguyen;Miyazawa, Teruo. And the article was included in Journal of Nutritional Science and Vitaminology in 2022.HPLC of Formula: 33171-05-0 The following contents are mentioned in the article:

Turmeric products have many useful physiol. functions and are widely used as health food and food ingredient. Here, we report the use of HPLC-ESI-MS/MS to simultaneously quantify bisacurone and three curcuminoids (curcumin, demethoxycurcumin, and bisdemethoxycurcumin) in turmeric products (high viscosity liquid, granular powder, tablet, and solution). The results showed that the standard values and measured values of curcumin in each product were almost same. Demethoxycurcumin and bisdeme-thoxycurcumin were contained in each products. Meanwhile, the content of bisacurone differed greatly among the products. In particular, the highest amount of bisacurone was found in the turmeric product A (high viscosity liquid, 9.48 g/100 g product). It would become important to consider the bisacurone content in turmeric products. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0HPLC of Formula: 33171-05-0).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.HPLC of Formula: 33171-05-0

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NADES-based surfactant-free microemulsions for solubilization and extraction of curcumin from Curcuma Longa was written by Huber, Verena;Muller, Laurie;Degot, Pierre;Touraud, Didier;Kunz, Werner. And the article was included in Food Chemistry in 2021.HPLC of Formula: 33171-05-0 The following contents are mentioned in the article:

A choline chloride + lactic acid (1:1) natural deep eutectic solvent (NADES) is used as an adjuvant to ethanol/triacetin mixtures to solubilize and extract curcumin from Curcuma Longa. The obtained NADES/ethanol/triacetin mixtures are homogeneous, transparent and of low viscosity even in the absence of water. Dynamic light scattering revealed significant nanostructures, typical of surfactant-free microemulsions. A twofold increase of curcumin solubility and remarkable extraction power (yield of ∼90%) can be achieved in the ternary system including the NADES, although curcumin is hydrophobic and the used NADES are very polar. Due to the elevated solubility of curcumin, more extraction cycles can be made than in the previously published aqueous systems with the same amount of solution As a result, less solvent is required to achieve the same extraction yield. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0HPLC of Formula: 33171-05-0).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.HPLC of Formula: 33171-05-0

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Shedding light on curcumin stability was written by Appendino, Giovanni;Allegrini, Pietro;de Combarieu, Eric;Novicelli, Federico;Ramaschi, Giuseppe;Sardone, Nicola. And the article was included in Fitoterapia in 2022.Synthetic Route of C19H16O4 The following contents are mentioned in the article:

The stability of mol. curcumin (purcumin, 1a) in solution is strongly light-dependent. Under laboratory artificial light, a relative stability is observed only at neutral pH, while more intense light and/or solar light can trigger degradation via a combination of hydrolytic and oxidative fragmentation of the heptadiendione moiety. Minor curcuminoids in com. curcumin (purcuminoids) can improve the stability of mol. curcumin, but only under conditions of low irradiation While confirming earlier observations alerting to the instability of purcumin, our results provide new rationales for unexplained differences between previous studies, question the biol. relevance of a non-enzymic degradation for the bioactivity profiles that have been reported for purcumin, and highlight the need of a better characterization of the degradation of purcuminoids under visible light irradiation This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Synthetic Route of C19H16O4).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Synthetic Route of C19H16O4

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Curcumin: An Insight into Molecular Pathways Involved in Anticancer Activity was written by Joshi, Priyanka;Joshi, Sushil;Semwal, Deepak;Bisht, Akansha;Paliwal, Sarvesh;Dwivedi, Jaya;Sharma, Swapnil. And the article was included in Mini-Reviews in Medicinal Chemistry in 2021.Reference of 33171-05-0 The following contents are mentioned in the article:

A review. Curcuma longa has been mentioned in the Indian system of medicine for the management of a wide range of diseases. C. longa and its metabolites like curcumin, ar-turmerone, methylcurcumin, demethoxy-curcumin, and bisdemethoxycurcumin have also been reported to be beneficial in various types of cancer. Curcumin elicits anticancer properties chiefly by triggering apoptotic pathways in cancer cells. The properties are facilitated through diverse signaling pathways viz. pathways mediated by NF-kB, WNT/β-catenin pathway COX-2, LOX, STAT3, prostaglandin E2, phosphorylase kinase, VEGF, AKT, AP1, STAT3, PI3K, Akt, mTOR, ERK5, AP-1, TGF-b, PPARc, EBPa, NLRP3 inflammasome, p38MAPK, Nrf2, Notch-1, AMPK, TLR-4, etc. The present article highlights curcumin biosynthesis, phytochem. and diverse mol. pathways involved in regulating several types of secondary messengers to exhibit anticancer activity in almost all the forms of cancer. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Reference of 33171-05-0).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Reference of 33171-05-0

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Innovative methodological approach using CIELab and dye screening for chemometric classification and HPLC for the confirmation of dyes in cassava flour: A contribution to product quality control was written by Filgueiras Rebelo de Matos, Marcia;Quenia Muniz Bezerra, Priscilla;Conceicao Argolo Correia, Luciana;Nunes Viola, Denise;de Oliveira Rios, Alessandro;Izabel Druzian, Janice;Larroza Nunes, Itaciara. And the article was included in Food Chemistry in 2021.Formula: C19H16O4 The following contents are mentioned in the article:

A variety of methods for producing cassava flour exist, resulting in very heterogeneous products that exhibit various colors, textures, granulometries, and flavours. To improve its attractiveness to consumers, some producers dye cassava flour with turmeric or tartrazine; however, this practice is illegal in Brazil. In this study, cassava flour samples were collected and evaluated for possible adulteration by the addition of dyes. Flours were analyzed by CIELab and dye screening (paper chromatog. and the turmeric-identification method) and a classification tree was developed using these data. Pos. results for curcuminoid pigments or tartrazine were confirmed by HPLC-DAD or HPLC-UV-Vis, resp. The developed approach is an innovative alternative chemometric-anal. method that facilitates highly practical screening; adulterated cassava flour, a product of great human-food importance, can be identified using CIELab parameters. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Formula: C19H16O4).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Formula: C19H16O4

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Synbiotic Musa acuminata skin extract and Streptococcus salivarius K12 inhibit candida species biofilm formation was written by Rismayuddin, Nurul Alia Risma;Mohd Badri, Puteri Elysa Alia;Ismail, Ahmad Faisal;Othman, Noratikah;Bandara, H. M. H. N.;Arzmi, Mohd Hafiz. And the article was included in Biofouling in 2022.Synthetic Route of C19H16O4 The following contents are mentioned in the article:

This study aimed to determine the effect of synbiotic Musa acuminata skin extract (MASE) and Streptococcus salivarius K12 (K12) on Candida species biofilm formation. Liquid chromatog. quadrupole time-of-flight (LC-Q-TOF-MS) was conducted to characterize MASE. To determine the effect of synbiotic on Candida biofilm, 200 μL of RPMI-1640 containing Candida, K12, and MASE were pipetted into the same well and incubated at 37 °C for 72 h. A similar protocol was repeated with K12 or MASE to determine the probiotic and prebiotic effects, resp. Dimorphism, biofilm biomass, and Candida total cell count (TCC) were determined A total of 60 compounds were detected in MASE. C. albicans (ALT5) and Candida lusitaniae exhibited the highest reduction in biofilm biomass when co-cultured with prebiotic (77.70 ± 7.67%) and synbiotic (97.73 ± 0.28%), resp. All Candida spp. had decreased TCC and hyphae when co-cultured with synbiotic. In conclusion, MASE and K12 inhibit Candida biofilm formation. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Synthetic Route of C19H16O4).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Synthetic Route of C19H16O4

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Metabolomics-based profiling for quality assessment and revealing the impact of drying of Turmeric (Curcuma longa L.) was written by Salem, Mohamed A.;El-Shiekh, Riham A.;Fernie, Alisdair R.;Alseekh, Saleh;Zayed, Ahmed. And the article was included in Scientific Reports in 2022.Synthetic Route of C19H16O4 The following contents are mentioned in the article:

Turmeric, the rhizomes of Curcuma longa L., is one of the top selling spices, food preservatives, and food colorants. In addition, it exhibits health promoting benefits owing to its unique phytochem. composition Nevertheless, it is commonly subjected to heat drying, hence, the dried powder is the most used form and can easily be adulterated with allied species. Therefore, our research aimed to profile the phytochem. composition and investigate the impact of drying of turmeric. Extraction and fractionation followed by LC- and GC-MS anal. resulted in the identification of a total of 161 metabolites belonged to various phytochem. classes. Moreover, multivariate data anal. identified curcuminoids, terpecurcumins, and organic acids as potential markers for drying. Based on the applied anal. techniques in combination with chemometrics, these investigations have succeeded to provide good coverage of the metabolome of turmeric in both fresh and dried forms. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Synthetic Route of C19H16O4).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Synthetic Route of C19H16O4

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Curcumin extracts from Curcuma Longa – Improvement of concentration, purity, and stability in food-approved and water-soluble surfactant-free microemulsions was written by Degot, Pierre;Huber, Verena;Touraud, Didier;Kunz, Werner. And the article was included in Food Chemistry in 2021.Application of 33171-05-0 The following contents are mentioned in the article:

Curcumin was extracted from Curcuma Longa employing a green, bio-based, and food-agreed surfactant-free microemulsion (SFME) consisting of water, ethanol, and triacetin. Concerning the high solubility of curcumin in the examined ternary mixtures, it was attempted to produce highly concentrated tinctures of up to a total of ∼130 mg/mL curcuminoids in the solvent by repeatedly extracting fresh rhizomes in the same extraction mixture The amount of water had a significant influence on the number of cycles that could be performed as well as on the extraction of the different curcuminoids. In addition, the purity of single extracts was enhanced to 94% by investigating several purification steps, e.g. vacuum distillation and lyophilization. Through purification before extraction, the water insoluble curcumin extract could be solubilized indefinitely in an aqueous environment. Addnl. stability tests showed that solutions of curcumin can be stable up to five months when concealed from natural light. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Application of 33171-05-0).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Application of 33171-05-0

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Existence of β-diketone form of curcuminoids revealed by NMR spectroscopy was written by Prasad, Durga;Praveen, Aishwarya;Mahapatra, Sipra;Mogurampelly, Santosh;Chaudhari, Sachin R.. And the article was included in Food Chemistry in 2021.Product Details of 33171-05-0 The following contents are mentioned in the article:

Curcumin (CUR), demethoxycurcumin (DMC) and bisdemethoxycurcumin (BDMC) – the class of natural compound derived from turmeric can exist as keto-enol and beta-diketone tautomer form. The structure and dynamics of particular relevance CUR is reported in prior studies, whereas DMC and BDMC, by far, have not been scrutinized. In the present studies, we have investigated the detailed mol. structure of CUR, DMC and BDMC by employing NMR spectroscopy as a key tool. The bridging carbon as methylene in beta-diketone form and methine in keto-enol form shows significant difference in NMR spectrum. The results justified that Curcuminoids (CC) has nearly 3% of beta-diketone tautomer in DMSO solvent at 298 K. Further, results revealed that beta-diketone form was favored in alk. pH condition whereas acidic and neutral pH conditions favor keto-enol tautomer. However, at higher temperature equilibrium shift towards beta-diketone tautomer. Moreover, this is the first report by NMR for observing the presence of beta-diketone tautomer. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Product Details of 33171-05-0).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Product Details of 33171-05-0

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Ether – Wikipedia,
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