Curcumin: An Insight into Molecular Pathways Involved in Anticancer Activity was written by Joshi, Priyanka;Joshi, Sushil;Semwal, Deepak;Bisht, Akansha;Paliwal, Sarvesh;Dwivedi, Jaya;Sharma, Swapnil. And the article was included in Mini-Reviews in Medicinal Chemistry in 2021.Reference of 33171-05-0 The following contents are mentioned in the article:
A review. Curcuma longa has been mentioned in the Indian system of medicine for the management of a wide range of diseases. C. longa and its metabolites like curcumin, ar-turmerone, methylcurcumin, demethoxy-curcumin, and bisdemethoxycurcumin have also been reported to be beneficial in various types of cancer. Curcumin elicits anticancer properties chiefly by triggering apoptotic pathways in cancer cells. The properties are facilitated through diverse signaling pathways viz. pathways mediated by NF-kB, WNT/β-catenin pathway COX-2, LOX, STAT3, prostaglandin E2, phosphorylase kinase, VEGF, AKT, AP1, STAT3, PI3K, Akt, mTOR, ERK5, AP-1, TGF-b, PPARc, EBPa, NLRP3 inflammasome, p38MAPK, Nrf2, Notch-1, AMPK, TLR-4, etc. The present article highlights curcumin biosynthesis, phytochem. and diverse mol. pathways involved in regulating several types of secondary messengers to exhibit anticancer activity in almost all the forms of cancer. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Reference of 33171-05-0).
Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Reference of 33171-05-0
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem