Category: 14542-71-3

Related Products of 14542-71-3, A common heterocyclic compound, 14542-71-3, name is 3,5-Dibromo-4-methylanisole, molecular formula is C8H8Br2O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Stage 2-9 – Intermediate A1 in Scheme 1 was synthesised in eight steps using processes described in patent WO 02/058695 ;

The synthetic route of 14542-71-3 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; CHROMA THERAPEUTICS LTD.; WO2008/53158; (2008); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Adding a certain compound to certain chemical reactions, such as: 14542-71-3, name is 3,5-Dibromo-4-methylanisole, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 14542-71-3, Application In Synthesis of 3,5-Dibromo-4-methylanisole

Step A: 2,6-Dibromo-4-methoxy-benzyl bromide To a suspension of 5.0 g of 2,6-dibromo-4-methoxytoluene in 90 mL of CCl4 was added N-bromosuccinimide and benzoyl peroxide. The resulting mixture was heated to reflux and stirred at the refluxing temperature while irradiating with a sunlamp for 2 h, then cooled and concentrated. The resulting residue was dissolved in 1:1 hexanes-Et2O and filtered through a pad of silica gel, then purified by flash chromatography on a Biotage 40M column, eluding with 98:2 hexanes-Et2O, to yield 2,6-Dibromo-4-methoxy-benzyl bromide as a pale yellow solid. IH NMR (500 MHz, 2,6-Dibromo-4-methoxy-benzyl bromide as a pale yellow solid. 1H NMR (500 MHz,

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 3,5-Dibromo-4-methylanisole, and friends who are interested can also refer to it.