Adding a certain compound to certain chemical reactions, such as: 14542-71-3, name is 3,5-Dibromo-4-methylanisole, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 14542-71-3, Application In Synthesis of 3,5-Dibromo-4-methylanisole
Step A: 2,6-Dibromo-4-methoxy-benzyl bromide To a suspension of 5.0 g of 2,6-dibromo-4-methoxytoluene in 90 mL of CCl4 was added N-bromosuccinimide and benzoyl peroxide. The resulting mixture was heated to reflux and stirred at the refluxing temperature while irradiating with a sunlamp for 2 h, then cooled and concentrated. The resulting residue was dissolved in 1:1 hexanes-Et2O and filtered through a pad of silica gel, then purified by flash chromatography on a Biotage 40M column, eluding with 98:2 hexanes-Et2O, to yield 2,6-Dibromo-4-methoxy-benzyl bromide as a pale yellow solid. IH NMR (500 MHz, 2,6-Dibromo-4-methoxy-benzyl bromide as a pale yellow solid. 1H NMR (500 MHz,
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 3,5-Dibromo-4-methylanisole, and friends who are interested can also refer to it.