Month: October 2022

Tang, Huiling; Liu, Mengna; Zhu, Meiqi; Cui, Benqiang; Shi, Yanhui; Cao, Changsheng published an article in 2021. The article was titled 《C(sp2)-C(sp2) Suzuki cross-coupling of arylammonium salts catalyzed by a stable Pd-NHC complex》, and you may find the article in Tetrahedron.Formula: C7H9BO3 The information in the text is summarized as follows:

The authors developed the Suzuki-Miyaura cross-coupling of aryl ammonium salts via C-N bond activation catalyzed by an easily prepared and bench-stable palladium-N-heterocyclic carbene complex. The reaction proceeded well under mild conditions with phenylboronic acid and pinacol ester or anhydride and provided biaryls Ar1-Ar2 [Ar1 = 1-naphthyl, Ph, 2-pyridyl, etc., Ar2 = Ph, 4-MeC6H4, 4-PhC6H4, etc.] in up to 97% yield with good functional group compatibility. The direct arylation of arylamine could be performed by a two-step, one-pot process and a protocol could be performed on the gram scale. After reading the article, we found that the author used 3-Methoxyphenylboronic acid(cas: 10365-98-7Formula: C7H9BO3)

3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.Formula: C7H9BO3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Xue, Sijing; Cristofol, Alex; Limburg, Bart; Zeng, Qian; Kleij, Arjan W. published an article in ACS Catalysis. The title of the article was 《Dual Cobalt/Organophotoredox Catalysis for Diastereo- and Regioselective 1,2-Difunctionalization of 1,3-Diene Surrogates Creating Quaternary Carbon Centers》.HPLC of Formula: 60656-87-3 The author mentioned the following in the article:

The synthesis of quaternary carbons RCH(OH)C(R1)(Me)CH=CH2(R = Ph, naphthalen-2-yl, 4-(prop-1-en-2-yl)cyclohex-1-en-1-yl, furan-2-yl, etc.; R1 = Ph, 4-MeOPh, 4-MePh, 4F-Ph, 4-Cl-Ph, etc.) through a catalytic stereo- and regioselective difunctionalization of 2-substituted 1,3-dienes C6H5CH(OH)C(C6H5)(CH2R2)CH=CH2 remains elusive. Here, a dual Co/photoredox-catalyzed cascade approach that addresses this challenge using modular vinyl cyclic carbonates functioning as masked 2-aryl-1,3-dienes I surrogates was presented. The latter species are conveniently prepared in situ and converted into nucleophilic Co(allyl) intermediates that are intercepted by aldehydes to afford homoallylic alcs. compound (I) with ample scope in reaction partners. The developed protocol marks a significant step forward in the use of structurally versatile 1,3-dienes I and their catalytic 1,2-hydroalkylation and 1,2-dicarbofunctionalization. In the experimental materials used by the author, we found 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3HPLC of Formula: 60656-87-3)

2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) is a non-natural aldehyde. It undergoes enantioselective Mukaiyama aldol reaction with silylketene acetal nucleophiles in the presence of C2-symmetric bis(oxazolinyl)pyridine Cu(II) complex (catalyst).HPLC of Formula: 60656-87-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Related Products of 10365-98-7In 2021 ,《Magnetic Circularly Polarized Luminescence in the Photoexcited States of Racemic [n]Helicenes (n=3-5,7) in Tetrahydrofuran and Dimethyl Sulfoxide Solutions》 appeared in ChemPhysChem. The author of the article were Toda, Hayato; Otake, Shuhei; Ito, Akari; Miyasaka, Makoto; Fujiki, Michiya; Imai, Yoshitane. The article conveys some information:

This paper reports the first magnetic circularly polarized luminescence (MCPL) characteristics of racemic helicenes, including four unsubstituted [n]helicenes (n=3,4,5,7) and two [4]helicene derivatives bearing methoxy substituents, in THF (THF) and DMSO (DMSO) solutions The value of |gMCPL| was calculated to be of the order of 10-3 T-1 within 350-430 nm under the north-up (N-up) and south-up (S-up) Faraday geometries in an external magnetic field of 1.6 T. The [n]-dependent MCPL signs were altered by the N-up and S-up geometries. In the experiment, the researchers used 3-Methoxyphenylboronic acid(cas: 10365-98-7Related Products of 10365-98-7)

3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.Related Products of 10365-98-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Computed Properties of C12H10S2In 2020 ,《Cryogenic grinding performance of scrap tire rubber by devulcanization treatment with ScCO2》 was published in Powder Technology. The article was written by Li, Xiang; Xu, Xiaofei; Liu, Zhijun. The article contains the following contents:

The cryogenic grinding performance of scrap tire rubber modified by devulcanization treatment in supercritical carbon dioxide (ScCO2) was studied with a fluidized-bed jet mill. Scrap tire rubbers devulcanized with various concentrations of devulcanizing reagents were ground to analyze the effect of the degree of devulcanization on the particle size distribution of the ground product. Population balance modeling based on selection and breakage functions was adopted to explore the evolution rule of the particle sizes in the grinding process. The results of the cryogenic grinding experiment show that the devulcanization treatment can promote particle size reduction and lead to the transformation of the grinding mechanism from abrasion to cleavage or fracture. Furthermore, Kapur function fitted by the population balance modeling was proposed with a cubic polynomial, and the calculation results agreed well with the exptl. data. In addition to this study using 1,2-Diphenyldisulfane, there are many other studies that have used 1,2-Diphenyldisulfane(cas: 882-33-7Computed Properties of C12H10S2) was used in this study.

1,2-Diphenyldisulfane(cas: 882-33-7) belongs to ethers.Computed Properties of C12H10S2Although ethers resist hydrolysis, they are cleaved by hydrobromic acid and hydroiodic acid. Hydrogen chloride cleaves ethers only slowly.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Recommanded Product: 1,2-DiphenyldisulfaneIn 2019 ,《Catalyst-Free gem-Difunctionalization of Fluoroalkyl-Substituted Diazo Compound with Diselenide or Disulfide and NFSI》 was published in Organic Letters. The article was written by Li, Jiuling; Ma, Chaoqun; Xing, Dong; Hu, Wenhao. The article contains the following contents:

Diazo compounds such as F3CCH:N2 underwent difunctionalization reactions with diselenides, disulfides, or di-Ph ditelluride and N-fluorobenzenesulfonimide in CH2Cl2 to yield α-seleno-, α-thio-, or α-(phenyltelluro)alkylsulfonimides such as F3CCH(SePh)N(SO2Ph)2. Preliminary mechanistic studies indicate that a selenoimidate intermediate generated from diselenide and NFSI is involved for this transformation. The experimental part of the paper was very detailed, including the reaction process of 1,2-Diphenyldisulfane(cas: 882-33-7Recommanded Product: 1,2-Diphenyldisulfane)

1,2-Diphenyldisulfane(cas: 882-33-7) belongs to ethers.Ethers do have nonbonding electron pairs on their oxygen atoms, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Recommanded Product: 1,2-Diphenyldisulfane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthetic Route of C12H10S2In 2019 ,《Fe(III)-Catalyzed direct C3 chalcogenylation of indole: the effect of iodide ions》 was published in Tetrahedron. The article was written by Luz, Eduardo Q.; Seckler, Diego; Araujo, Janylson Souza; Angst, Leonardo; Lima, David B.; Maluf Rios, Elise Ane; Ribeiro, Ronny R.; Rampon, Daniel S.. The article contains the following contents:

A mild and efficient protocol for the synthesis of selenyl/sulfenyl-indoles I [R = H, Me, SPh, SePh; R1 = H, Me, Bn; R2 = Me, SPh, SePh, etc.] was developed via iron (III)-catalyzed C3 chalcogenylation of indoles with (diaryl)disulfides/diselenides and the role of the iodide ions in this transformation was investigated. EPR experiments revealed the reduction of Fe(III) to Fe(II) under the reaction conditions, supported the formation of mol. iodine in the system, which in effect catalyze the reaction. The scope of the chalcogenylation was broad. In the experiment, the researchers used many compounds, for example, 1,2-Diphenyldisulfane(cas: 882-33-7Synthetic Route of C12H10S2)

1,2-Diphenyldisulfane(cas: 882-33-7) belongs to ethers.Synthetic Route of C12H10S2Although ethers resist hydrolysis, they are cleaved by hydrobromic acid and hydroiodic acid. Hydrogen chloride cleaves ethers only slowly.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Reference of m-MethoxyphenolIn 2019 ,《Construction of Spirocyclic Tetrahydro-β-carbolines via Cross-Annulation of Phenols with Tryptamines in Water》 was published in Organic Letters. The article was written by Wang, Zemin; Niu, Jiabin; Zeng, Huiying; Li, Chao-Jun. The article contains the following contents:

Phenols are readily available by degradation of lignin resource. Palladium-catalyzed conversion of phenols to tetrahydro-β-carboline skeletons bearing a spirocycle at the C-1 position in water is reported. Various substituted phenols are successfully cross-annulated with different tryptamines via sequential C(Ar)-O bond cleavage of phenols, C-H bond activation of tryptamines, and C-N/C-C bond formations. This method provides a new protocol of converting lignin phenols into high-value-added compounds, such as natural product Komavine. In the experimental materials used by the author, we found m-Methoxyphenol(cas: 150-19-6Reference of m-Methoxyphenol)

m-Methoxyphenol(cas: 150-19-6) may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.Reference of m-Methoxyphenol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Formula: C8H8O3In 2019 ,《Syntheses, structures and Hirschfeld analyses of trinuclear Ni(Π) salamo-type complexes》 was published in Wuji Huaxue Xuebao. The article was written by Yu, Meng; Mu, Hao-ran; Liu, Ling-zhi; Li, Na; Bai, Yang; Dong, Xiu-yan. The article contains the following contents:

Two newly designed complexes, {[Ni(L1)(n-propanol)]2(OAc)2Ni}·2(n-propanol) (1) and {[Ni(L2)(n-butanol)]2(OAc)2Ni}·2(n-butanol) (2) derived from tetradentate Salamo-type chelating ligands (H2L1=5-methoxy-2,2′-(ethylenedioxybis(azomethine))diphenol and H2L2=4,4′-dinitro-2,2′-(ethylenediyldioxybis(nitrilomethylidyne))diphenol) have been synthesized and characterized by elemental analyses, IR and UV-Vis spectra, Hirschfeld surfaces analyses and single crystal X-ray crystallog. X-ray crystallog. analyses showed that complexes 1 and 2 are all sym. trinuclear Ni(Π) complexes. Nickel(Π) in both 1 and 2 is hexa-coordinated, forming a twisted octahedral geometry. Both crystal structure and Hirschfeld surface anal. indicate that 1 and 2 form stable one-dimensional chain and two-dimensional supramol. structures, resp., by intermol. hydrogen bonding. The results came from multiple reactions, including the reaction of 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Formula: C8H8O3)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.Formula: C8H8O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

SDS of cas: 139115-91-6In 2019 ,《Design and synthesis of trivalent Tn glycoconjugate polymers by nitroxide-mediated polymerization》 was published in Tetrahedron. The article was written by Liu, Si-Xian; Tsai, Yun-Tzu; Lin, Yu-Tung; Li, Jia-Yue; Chang, Che-Chien. The article contains the following contents:

A new synthetic method for preparing Tn glycoconjugate polymers, containing tumor-associated carbohydrate antigens, by controlled living radical polymerization is reported. To mimic the authentic structures of Tn glycopeptide antigens and to explore the controlled living radical polymerization, three tumor-associated carbohydrate antigens (GalNAc, GalNAcα1-O-Ser, and GalNAcα1-O-Thr) were attached to a styrene-type monomer through a diethylene glycol spacer. Under nitroxide-mediated polymerization, controlled living radical polymerization proceeded to afford defined glycopeptide polymers with different Tn densities and compositions The polydispersity index (PDI) and mol. weights were increased and conversions were decreased upon increasing the concentration of Tn glycoconjugate monomers. The resulting Tn glycoconjugate polymers were characterized by NMR and IR. The spectral data indicate that the Tn glycoconjugate moiety did attach to the polymer chain and Tn glycoconjugate d. could be adjusted through the nitroxide-mediated polymerization conditions. The number of Tn units containing in the polymer chains could be estimated by NMR integration. This synthetic approach provides a new and efficient tool for constructing novel Tn glycoconjugate polymers. The results came from multiple reactions, including the reaction of tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6SDS of cas: 139115-91-6)

tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6) belongs to ethers. Ethers lack the hydroxyl groups of alcohols. SDS of cas: 139115-91-6 Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《A new zinc(II) complex with N2O2-tetradentate Schiff-base derived from pyridoxal-S-methylthiosemicarbazone: Synthesis, characterization, crystal structure, DFT, molecular docking and antioxidant activity studies》 was written by Poladian, Qumars; Sahin, Onur; Karakurt, Tuncay; Ilhan-Ceylan, Berat; Kurt, Yasemin. Related Products of 673-22-3This research focused onzinc Schiff methylthiosemicarbazone hydroxymethoxybenzaldehyde complex preparation antioxidant; frontier mol orbital zinc Schiff methylthiosemicarbazone hydroxymethoxybenzaldehyde complex; crystal structure zinc Schiff methylthiosemicarbazone hydroxymethoxybenzaldehyde complex. The article conveys some information:

A new unsym. N2O2-tetradentate Schiff-base complex of zinc(II) was synthesized by the template reaction of pyridoxal-S-methylthiosemicarbazone and 2-hydroxy-4-methoxy-benzaldehyde as starting compounds S-methylthiosemicarbazone (1) and zinc(II) complex [Zn(L)CH3OH] (2) were characterized by elemental anal., FT-IR, UV-visible, 1H, and 13C NMR spectra. The mol. structure of 2 was determined by single crystal X-ray diffraction technique. The structure consists of a distorted square-pyramidal geometry around the central metal, Zn(II). Quantum chem. calculations were carried out using d. functional theory DFT/B3LYP, 6-31G (d), and LanL2DZ basis sets for theor. characterization of the compounds The exptl. and theor. data were compared comprehensively. The potential energy distribution (PED) anal. was performed for the assignment of vibration frequencies. In order to support in vitro studies, mol. docking studies were carried out so that the title compound can be an inhibitor of Epidermal Growth Factor Receptor (1 m17), and the relationship between calculated HOMO energies and docking studies was examined In addition, the total antioxidant capacity (as TEAC value) and free radical scavenging activity of the compounds were determined by Cupric Reducing Antioxidant Capacity (CUPRAC) and 1,1-diphenyl-2-picryl hydrazyl (DPPH) methods, resp. In the experimental materials used by the author, we found 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Related Products of 673-22-3)

2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.Related Products of 673-22-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem