Month: October 2022

Hallas, G.; Yoon, Chun published their research in Dyes and Pigments on February 28 ,2001. The article was titled 《The synthesis and properties of red and blue benzodifuranones》.Application of 79694-16-9 The article contains the following contents:

In this study, red and blue benzodifuranones have been synthesized and their phys. properties measured. Red benzodifuranones were synthesized from half-condensed benzofuranone intermediates and alkoxymandelic acid derivatives Blue benzodifuranones were synthesized from the half-condensed intermediates and phenyltartronic acid derivatives In the experiment, the researchers used 2-Hydroxy-2-(4-propoxyphenyl)acetic acid(cas: 79694-16-9Application of 79694-16-9)

2-Hydroxy-2-(4-propoxyphenyl)acetic acid(cas: 79694-16-9) belongs to ethers.The C-O bonds that comprise simple ethers are strong. Application of 79694-16-9 They are unreactive toward all but the strongest bases. Although generally of low chemical reactivity, they are more reactive than alkanes.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2018,Molecules included an article by Tsakama, Madalitso; Ma, Xiaochi; He, Yonghuan; Chen, Weihua; Dai, Xiaofeng. Formula: C12H10O2. The article was titled 《A simple mannose-coated poly (p-phenylene ethynylene) for qualitative bacterial capturing》. The information in the text is summarized as follows:

A mannose-functionalized poly (p-phenylene ethynylene) was rationally designed to achieve selective detection of bacteria. The polymer was constructed as a signaling unit and was modified by attaching aminoethyl mannose using the carboxylic acid group at the end of the linker. Incubation of Escherichia coli with the polymer yielded fluorescent bacteria aggregates through polyvalent interactions. The utility of the mannose functionalized polymer to detect E. coli expressing functional FimH mannose-specific lectin on their surface was also demonstrated. The sugar units displayed on the surface of the polymer retained their functional ability to interact with mannose-binding lectin. To determine the optimum binding time, we measured the fluorescence intensity of the polymer-bacteria suspension at intervals. Our results showed that binding in this system will reach an optimum level within 30 min of incubation. The polymers affinity for bacteria has been demonstrated and bacteria with a concentration of 103 CFU mL-1 can be detected by this system. After reading the article, we found that the author used 1,4-Diethynyl-2,5-dimethoxybenzene(cas: 74029-40-6Formula: C12H10O2)

1,4-Diethynyl-2,5-dimethoxybenzene(cas: 74029-40-6) belongs to ethers.Oxygen is more electronegative than carbon, thus the alpha hydrogens of ethers are more acidic than those of simple hydrocarbons. Formula: C12H10O2 They are far less acidic than alpha hydrogens of carbonyl groups (such as in ketones or aldehydes), however.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Organic Letters included an article by Hoang, Gia L.; Zoll, Adam J.; Ellman, Jonathan A.. Synthetic Route of C9H10O2. The article was titled 《Three-Component Coupling of Aldehydes, 2-Aminopyridines, and Diazo Esters via Rhodium(III)-Catalyzed Imidoyl C-H Activation: Synthesis of Pyrido[1,2-a]pyrimidin-4-ones》. The information in the text is summarized as follows:

Imines formed in situ from 2-aminopyridines and aldehydes undergo Rh(III)-catalyzed imidoyl C-H activation and coupling with diazo esters to give pyrido[1,2-a]pyrimidin-4-ones. Aromatic and enolizable aliphatic aldehydes were both effective substrates, and a broad range of functional groups were incorporated at different sites on the heterocyclic products. In addition, methoxy and dimethylamino functionalities could be directly installed on the pyrimidine ring by employing tri-Me orthoformate or N,N-dimethylformamide di-Me acetal in place of the aldehyde, resp. The results came from multiple reactions, including the reaction of 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Synthetic Route of C9H10O2)

2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) may be used in the following syntheses: (3S,5S)-methyl 6-benzyloxy-3,5-dihydroxyhexanoate ,(S)-5-benzyloxy-4-hydroxypentan-2-one, myxothiazols.Synthetic Route of C9H10O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Organic Letters included an article by Peng, Jin-Bao; Li, Da; Geng, Hui-Qing; Wu, Xiao-Feng. Recommanded Product: 10365-98-7. The article was titled 《Palladium-Catalyzed Amide Synthesis via Aminocarbonylation of Arylboronic Acids with Nitroarenes》. The information in the text is summarized as follows:

A palladium-catalyzed aminocarbonylation of aryl boronic acids with nitroarenes for the synthesis of amides was developed. A wide range of substrates were well-tolerated and gave the corresponding amides in moderate to good yields. No external oxidant or reductant was needed in this procedure. This procedure provides a redox-economical process for the synthesis of amides. In addition to this study using 3-Methoxyphenylboronic acid, there are many other studies that have used 3-Methoxyphenylboronic acid(cas: 10365-98-7Recommanded Product: 10365-98-7) was used in this study.

3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.Recommanded Product: 10365-98-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,ACS Catalysis included an article by Fricke, Christoph; Dahiya, Amit; Reid, William B.; Schoenebeck, Franziska. Formula: C7H7IO. The article was titled 《Gold-Catalyzed C-H Functionalization with Aryl Germanes》. The information in the text is summarized as follows:

The development of orthogonal Csp2-Csp2 coupling regimes to the omnipresent Pd-catalysis class would enable an addnl. dimension of modularity in the construction of densely functionalized biaryl motifs. In this context, the identification of potent functional groups for selective transformations is in high demand. Although organogermanium compounds are generally believed to be of low reactivity in homogenous catalysis, this report discloses the highly efficient and orthogonal reactivity of aryl germanes with arenes under gold catalysis. The method is characterized by mildness, the employment of an air- and moisture-stable gold catalyst, and robustness. Our mechanistic studies show that aryl germanes are highly reactive with Au(I) and Au(III). Our computational data suggest that the origin of this reactivity primarily lies in the relatively low bond dissociation energy and as such low distortion energy to reach the key bond activating transition state. In addition to this study using 1-Iodo-2-methoxybenzene, there are many other studies that have used 1-Iodo-2-methoxybenzene(cas: 529-28-2Formula: C7H7IO) was used in this study.

1-Iodo-2-methoxybenzene(cas: 529-28-2) is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.Formula: C7H7IO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,ChemistrySelect included an article by Maddila, Suresh; Nagaraju, Kerru; Chinnam, Sampath; Jonnalagadda, Sreekantha B.. Electric Literature of C8H8O2. The article was titled 《Microwave-Assisted Multicomponent Reaction: A Green and Catalyst-Free Method for the Synthesis of Poly-Functionalized 1,4-Dihydropyridines》. The information in the text is summarized as follows:

A facile and an efficient procedure for the synthesis of poly-substituted 1,4-dihydropyridine derivatives under catalyst-free conditions was established by a one-pot multi-component reaction in EtOH solvent under microwave irradiation (150 W). The remarkable benefits of this approach were: simple operation, non-toxic, short reaction time (< 5 min), excellent yields (93-98%), no column chromatog., clean reaction profile and environmentally friendly reaction. In addition to this study using 2-Methoxybenzaldehyde, there are many other studies that have used 2-Methoxybenzaldehyde(cas: 135-02-4Electric Literature of C8H8O2) was used in this study.

2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Electric Literature of C8H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Organometallics included an article by Choluj, Artur; Krzesinski, Pawel; Ruszczynska, Anna; Bulska, Ewa; Kajetanowicz, Anna; Grela, Karol. Category: ethers-buliding-blocks. The article was titled 《Noncovalent Immobilization of Cationic Ruthenium Complex in a Metal-Organic Framework by Ion Exchange Leading to a Heterogeneous Olefin Metathesis Catalyst for Use in Green Solvents》. The information in the text is summarized as follows:

A simple strategy for noncovalent immobilization of an olefin metathesis catalyst inside a (Cr)MIL-101-SO3Na metal-organic framework (MOF) was presented. The olefin metathesis active core-an alkylidene complex bearing an ammonium-tagged NHC ligand (Apeiron’s FixCat)-was immobilized by ion exchange facilitated using crown ether. The hybrid material thus obtained was shown with a number of model substrates to exhibit high activity and selectivity in a wide range of solvents. Next, selected polyfunctional pharmaceutically related substrates were transformed using 0.8-0.5 mol % of the Ru@MOF in polar solvents such as acetone and di-Me carbonate, making this technol. interesting in the context of green solvent use. In the experiment, the researchers used 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Category: ethers-buliding-blocks)

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Organic Letters included an article by Molloy, John J.; O’Rourke, Kerry M.; Frias, Carolina P.; Sloan, Nikki L.; West, Matthew J.; Pimlott, Sally L.; Sutherland, Andrew; Watson, Allan J. B.. Formula: C7H7IO. The article was titled 《Mechanism of Cu-Catalyzed Aryl Boronic Acid Halodeboronation Using Electrophilic Halogen: Development of a Base-Catalyzed Iododeboronation for Radiolabeling Applications》. The information in the text is summarized as follows:

An investigation into the mechanism of Cu-catalyzed aryl boronic acid halodeboronation using electrophilic halogen reagents is reported. Evidence is provided to show that this takes place via a boronate-driven ipso-substitution pathway and that Cu is not required for these processes to operate: general Lewis base catalysis is operational. This in turn allows the rational development of a general, simple, and effective base-catalyzed halodeboronation that is amenable to the preparation of 125I-labeled products for SPECT applications. In the experiment, the researchers used 1-Iodo-2-methoxybenzene(cas: 529-28-2Formula: C7H7IO)

1-Iodo-2-methoxybenzene(cas: 529-28-2) is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.Formula: C7H7IO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,ACS Omega included an article by Jadhav, Nirajkumar H.; Sakate, Sachin S.; Rasal, Nishant K.; Shinde, Dnyaneshwar R.; Pawar, Ramdas A.. Recommanded Product: m-Methoxyphenol. The article was titled 《Heterogeneously Catalyzed Pechmann Condensation Employing the Tailored Zn0.925Ti0.075O NPs: Synthesis of Coumarin》. The information in the text is summarized as follows:

A novel heterogeneous catalytic method was developed for the synthesis of coumarin and its derivatives using the Ti(IV)-doped ZnO matrix forming catalyst Zn0.925Ti0.075O having a high surface area and good Lewis acidity. The catalyst shows high activity toward a broad spectrum of the substituted phenols with β-ketoesters such as Et acetoacetate, Et butyryl acetate, Et benzoyl acetate, and so forth in good yields over short reaction times during the synthesis of coumarins. The methodol. was further extended for the synthesis of ayapin mols. The catalyst also shows recycle activity up to seven cycles with very good stability. After reading the article, we found that the author used m-Methoxyphenol(cas: 150-19-6Recommanded Product: m-Methoxyphenol)

m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneRecommanded Product: m-Methoxyphenol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《Rhenium-Catalyzed Regioselective ortho-Alkenylation and [3 + 2 + 1] Cycloaddition of Phenols with Internal Alkynes》 were Murai, Masahito; Yamamoto, Masaki; Takai, Kazuhiko. And the article was published in Organic Letters in 2019. COA of Formula: C7H8O2 The author mentioned the following in the article:

An operationally simple and direct rhenium-catalyzed ortho-alkenylation (C-alkenylation) of unprotected phenols with alkynes was developed. The protocol provided ortho-alkenylphenols exclusively, and formation of para- or multiply alkenylated phenols and hydrophenoxylation (O-alkenylation) products were not observed The [3 + 2 + 1] cycloaddition of phenols and two alkynes via ortho-alkenylation was also demonstrated, in which the alkynes functioned as both two- and one-carbon units. These reactions proceeded with readily available starting materials under neutral conditions without addnl. ligands. In the experimental materials used by the author, we found m-Methoxyphenol(cas: 150-19-6COA of Formula: C7H8O2)

m-Methoxyphenol(cas: 150-19-6) may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.COA of Formula: C7H8O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem