In 2019,Organometallics included an article by Choluj, Artur; Krzesinski, Pawel; Ruszczynska, Anna; Bulska, Ewa; Kajetanowicz, Anna; Grela, Karol. Category: ethers-buliding-blocks. The article was titled 《Noncovalent Immobilization of Cationic Ruthenium Complex in a Metal-Organic Framework by Ion Exchange Leading to a Heterogeneous Olefin Metathesis Catalyst for Use in Green Solvents》. The information in the text is summarized as follows:
A simple strategy for noncovalent immobilization of an olefin metathesis catalyst inside a (Cr)MIL-101-SO3Na metal-organic framework (MOF) was presented. The olefin metathesis active core-an alkylidene complex bearing an ammonium-tagged NHC ligand (Apeiron’s FixCat)-was immobilized by ion exchange facilitated using crown ether. The hybrid material thus obtained was shown with a number of model substrates to exhibit high activity and selectivity in a wide range of solvents. Next, selected polyfunctional pharmaceutically related substrates were transformed using 0.8-0.5 mol % of the Ru@MOF in polar solvents such as acetone and di-Me carbonate, making this technol. interesting in the context of green solvent use. In the experiment, the researchers used 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Category: ethers-buliding-blocks)
1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Category: ethers-buliding-blocks
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem