Month: November 2022

Electroselective and Controlled Reduction of Cyclic Imides to Hydroxylactams and Lactams was written by Bai, Ya;Shi, Lingling;Zheng, Lianyou;Ning, Shulin;Che, Xin;Zhang, Zhuoqi;Xiang, Jinbao. And the article was included in Organic Letters in 2021.HPLC of Formula: 109-85-3 The following contents are mentioned in the article:

An efficient and practical electrochem. method for selective reduction of cyclic imides has been developed using a simple undivided cell with carbon electrodes at room temperature The reaction provides a useful strategy for the rapid synthesis of hydroxylactams and lactams in a controllable manner, which is tuned by elec. current and reaction time, and exhibits broad substrate scope and high functional group tolerance even to reduction-sensitive moieties. Initial mechanistic studies suggest that the approach heavily relies on the utilization of amines (e.g., i-Pr₂NH), which are able to generate α-aminoalkyl radicals. This protocol provides an efficient route for the cleavage of C-O bonds under mild conditions with high chemoselectivity. This study involved multiple reactions and reactants, such as 2-Methoxyethylamine (cas: 109-85-3HPLC of Formula: 109-85-3).

2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. HPLC of Formula: 109-85-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Highly convergent modular access to poly-carbon substituted cyclopropanes via Cu(I)-catalyzed three-component cyclopropene carboallylation was written by Li, Hexin;Zhang, Mengru;Mehfooz, Haroon;Zhu, Dongxia;Zhao, Jinbo;Zhang, Qian. And the article was included in Organic Chemistry Frontiers in 2019.Category: ethers-buliding-blocks The following contents are mentioned in the article:

A conjunctive C-C cross-coupling of cyclopropenes enabled by a Cu-catalyzed three-component reaction of organoboron, cyclopropene and allylic bromide, which featured a modular, stereoselective assembly of poly-carbon substituted cyclopropanes I [R¹ = Ph, 4-MeC₆H₄, 2-naphthyl, etc.; R² = Me, Ph, 4-MeC₆H₄, etc.; R³ = Ph, 4-MeC₆H₄, 3-thienyl, etc.; R⁴ = H, Me, Br, etc.; R⁵ = H, F, CH₂CH₂CH:C(Me)₂, etc.; R⁶ = H, F, Me, etc.] was reported. Preliminary studies showed that the reaction could be extended to benzylation and made enantioselective with C2-sym. bisphosphine ligands. This study involved multiple reactions and reactants, such as 2-(3-Methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane (cas: 1003858-50-1Category: ethers-buliding-blocks).

2-(3-Methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane (cas: 1003858-50-1) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Multicomponent Cyclopropane Synthesis Enabled by Cu-Catalyzed Cyclopropene Carbometalation with Organoboron Reagent: Enantioselective Modular Access to Polysubstituted 2-Arylcyclopropylamines was written by Li, Zhanyu;Zhang, Mengru;Zhang, Yu;Liu, Shuang;Zhao, Jinbo;Zhang, Qian. And the article was included in Organic Letters in 2019.Product Details of 1003858-50-1 The following contents are mentioned in the article:

The use of functional-group-tolerant organoboron in lieu of basic organometallic reagents in base-metal-catalyzed cyclopropene carbometalation opens three-component cyclopropane synthesis, as exemplified by the modular assembly of the highly medicinally relevant 2-arylcyclopropylamine (ACPA) framework via stereoselective carboamination. The highly enantioselective version has been realized to afford enantioenriched ACPAs with up to all three cyclopropyl carbons as stereogenic centers in one operation, representing the first example of enantioselective multicomponent cyclopropane synthesis. The reaction significantly improves the efficiency of ACPA synthesis and may inspire the development of other multicomponent cyclopropane syntheses beyond amination. This study involved multiple reactions and reactants, such as 2-(3-Methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane (cas: 1003858-50-1Product Details of 1003858-50-1).

2-(3-Methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane (cas: 1003858-50-1) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Product Details of 1003858-50-1

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis, biophysical characterization, and anti-HIV-1 fusion activity of DNA helix-based inhibitors with a p-benzyloxyphenyl substituent at the 5′-nucleobase site was written by Tang, Yongjia;Han, Zeye;Guo, Jiamei;Tian, Yangli;Liu, Keliang;Xu, Liang. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2018.Computed Properties of C13H12O2 The following contents are mentioned in the article:

DNA helix-based HIV-1 fusion inhibitors have been discovered as potent drug candidates. Introduction of hydrophobic groups to a nucleobase provides an opportunity to design inhibitors with novel structures and mechanisms of action. In this work, two novel nucleoside analogs (1 and 2) were synthesized and incorporated into four DNA duplex- and quadruplex-based inhibitors. All the mols. showed anti-HIV-1 fusion activity. The effect of the p-benzyloxyphenyl group and the attached linker on the helix formation and thermal stability were fully compared and discussed. Surface plasmon resonance anal. further indicated that inhibitors with the same DNA helix may still have variable reaction targets, mainly attributed to the different hydrophobic modifications. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Computed Properties of C13H12O2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Computed Properties of C13H12O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Facile determination of foamability index of non-ionic and cationic frothers and its effect on flotation of quartz was written by Kowalczuk, Przemyslaw B.;Siedlarz, Marta;Szczerkowska, Sabina;Wojcik, Marta. And the article was included in Separation Science and Technology in 2018.Recommanded Product: 112-59-4 The following contents are mentioned in the article:

In this work, a facile method for determination of foaming properties of frothers was used. It was based on measuring the foam height in a flotation machine at different concentrations of frothers. Based on the foam height-concentration curve, a new foaming parameter, so-called concentration at half of the maximum foam height CMH, was proposed. Assessment and usefulness of CMH were shown in flotation of quartz. The concentration of amine at the critical contact angle CCA, at which amine starts to be a collector, was also determined The determined values of CCA were similar to CMH and were equal to 1.3, 0.14 and 0.03 mM for ButNH₂, HexNH₂ and OctNH₂, resp. The values of CMH and CCA depended on the alkyl chain of frothers. This study involved multiple reactions and reactants, such as 2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4Recommanded Product: 112-59-4).

2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Recommanded Product: 112-59-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Simplex lattice design for optimization of the mass ratio of Curcuma longa L., Curcuma zedoaria (Christm.) Roscoe and Curcuma aromatica Salisb. to maximize curcuminoids content and antioxidant activity was written by Monton, Chaowalit;Chuanchom, Panupong;Popanit, Puwadon;Settharaksa, Sukanya;Pathompak, Pathamaporn. And the article was included in Acta Pharmaceutica (Warsaw, Poland) in 2021.Quality Control of Bisdemethoxycurcumin The following contents are mentioned in the article:

The aim of this work was to optimize the mass ratio of three Curcuma plants’ rhizomes to obtain the highest curcuminoid content and antioxidant activity using the simplex lattice design. The selected Curcuma plants were C. longa, C. zedoaria and C. aromatica. The simplex lattice design was applied in the work. The individual curcuminoids (curcumin, demethoxycurcumin and bis-demethoxycurcumin) and total curcuminoid content were determined using high-performance liquid chromatog. Curcuma longa alone provided the highest content of bis-demethoxycurcumin and demethoxycurcumin. A mixture of C. longa and C. aromatica in the mass ratio of 72:28% provided the highest curcumin content. The results showed that C. longa alone exhibited the highest antioxidant activity. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Quality Control of Bisdemethoxycurcumin).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Quality Control of Bisdemethoxycurcumin

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Self-Diffusion of End-Capped Oligo(ethylene glycol)s in Poly(vinyl alcohol) Aqueous Solutions and Gels was written by Masaro, L.;Zhu, X. X.. And the article was included in Macromolecules in 1999.Quality Control of 2-(2-(Hexyloxy)ethoxy)ethanol The following contents are mentioned in the article:

We have studied the self-diffusion of a series of end-capped ethylene glycol and oligo(ethylene glycol)s in poly(vinyl alc.) aqueous solutions and gels by pulsed-gradient spin echo NMR spectroscopy. The end groups of the diffusants include small flexible groups (Me, Et, hexyl) and bulky rigid groups (tert-Bu and aromatic groups). The effect of the size and geometry of the end groups on the self-diffusion coefficients of the derivatives of ethylene glycol and of oligo(ethylene glycol)s is investigated. The diffusion data are analyzed with several phys. models of diffusion based on different phys. concepts to test their applicabilities. The variation of the parameters used in these diffusion models with the size and geometry of the diffusants is also discussed. This study involved multiple reactions and reactants, such as 2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4Quality Control of 2-(2-(Hexyloxy)ethoxy)ethanol).

2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Quality Control of 2-(2-(Hexyloxy)ethoxy)ethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis and characterization of novel 4-benzyloxyphenyl 4-[4-(n-dodecyloxy) benzoyloxy]benzoate liquid crystal was written by Balkanli, Emine;Cakar, Fatih;Ocak, Hale;Cankurtaran, Ozlem;Eran, Belkiz Bilgin. And the article was included in Turkish Journal of Chemistry in 2021.Computed Properties of C13H12O2 The following contents are mentioned in the article:

Liquid crystal (LC) compound 4-benzyloxyphenyl 4-[4-(n-dodecyloxy)benzoyloxy]benzoate (BDBB) was prepared and characterized. Inverse gas chromatog. (IGC) was to be a beneficial anal. method for the research of thermodn. characteristics of the new LC. Acetate and alc. isomers were used to examine LC selectivity via the IGC technique at temperatures between 333.2 K and 483.2 K. The retention diagrams of n-heptane, n-octane, n-nonane, n-decane, undecane, dodecane, tridecane, Bu acetate, iso-Bu acetate, Et acetate, n-propylbenzene, isopropylbenzene, ethylbenzene, chlorobenzene and toluene on BDBB were plotted with temperatures of 483.2-493.2 K. Flory-Huggins interaction parameter and weight fraction activity coefficient at infinite dilution were researched for BDBB. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Computed Properties of C13H12O2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Computed Properties of C13H12O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis and characterization of novel 4-benzyloxyphenyl 4-[4-(n-dodecyloxy) benzoyloxy]benzoate liquid crystal was written by Balkanli, Emine;Cakar, Fatih;Ocak, Hale;Cankurtaran, Ozlem;Eran, Belkiz Bilgin. And the article was included in Turkish Journal of Chemistry in 2021.Category: ethers-buliding-blocks The following contents are mentioned in the article:

Liquid crystal (LC) compound 4-benzyloxyphenyl 4-[4-(n-dodecyloxy)benzoyloxy]benzoate (BDBB) was prepared and characterized. Inverse gas chromatog. (IGC) was to be a beneficial anal. method for the research of thermodn. characteristics of the new LC. Acetate and alc. isomers were used to examine LC selectivity via the IGC technique at temperatures between 333.2 K and 483.2 K. The retention diagrams of n-heptane, n-octane, n-nonane, n-decane, undecane, dodecane, tridecane, Bu acetate, iso-Bu acetate, Et acetate, n-propylbenzene, isopropylbenzene, ethylbenzene, chlorobenzene and toluene on BDBB were plotted with temperatures of 483.2-493.2 K. Flory-Huggins interaction parameter and weight fraction activity coefficient at infinite dilution were researched for BDBB. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Category: ethers-buliding-blocks).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Dehydrocoupling of boranes with amines using a scandium catalyst was written by Wang, Yang;Xu, Pengfei;Xu, Xin. And the article was included in Chinese Chemical Letters in 2021.SDS of cas: 109-85-3 The following contents are mentioned in the article:

The scandocene alkyl complex (C₅Me₅)₂ScCH₂SiMe₃ was found to be an efficient catalyst for the dehydrocoupling of the non-cyclic boranes, dicyclohexylborane and thexylborane, with amines under mild conditions. The reactions afforded the corresponding aminoboranes in high yields with good functional group tolerance. The stoichiometric reaction of scandium alkyl with amine led to the isolation of a scandium amide complex, which was shown to be an active species during the catalysis. Although a borane-coordinated scandium hydride was also obtained from the stoichiometric experiment, it was not involved in the catalytic cycle. In addition, kinetic studies provided insight into this intermol. dehydrogenation reaction. This study involved multiple reactions and reactants, such as 2-Methoxyethylamine (cas: 109-85-3SDS of cas: 109-85-3).

2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.SDS of cas: 109-85-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem