Month: November 2022

Small-angle neutron scattering studies of aqueous solutions of short-chain amphiphiles was written by D’Arrigo, G.;Giordano, R.;Teixeira, J.. And the article was included in European Physical Journal E: Soft Matter in 2003.Product Details of 112-59-4 The following contents are mentioned in the article:

The authors present small angle neutron scattering measurements on binary aqueous solutions of some short-chain amphiphiles (diols, triols, glycols and diglycols) at room temperature The spectra were analyzed in terms of the Teubner-Strey phenomenol. formula which allows to obtain a measure for the amphiphilicity strength of each system (amphiphilicity factor f_a). In some systems, however, other models, valid for micellar solutions, give also a good representation of the spectra. As a result, independently of the type of hydrophilic group side (oxydrilic or oxirane), these systems cover the entire accessible amphiphilicity scale (-1 < f_a < 1). Some disordered systems (f_a > 1) presumably are able to form micelle-like aggregates. This study involved multiple reactions and reactants, such as 2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4Product Details of 112-59-4).

2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Product Details of 112-59-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Discovery of 3-aryl substituted benzoxaboroles as broad-spectrum inhibitors of serine- and metallo-β-lactamases was written by Yan, Yu-Hang;Li, Zhao-Feng;Ning, Xiang-Li;Deng, Ji;Yu, Jun-Lin;Luo, Yubin;Wang, Zhenling;Li, Guo;Li, Guo-Bo;Xiao, You-Cai. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2021.Application In Synthesis of 5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde The following contents are mentioned in the article:

The production of β-lactamases represents the main cause of resistance to clin. important β-lactam antibiotics. Boron containing compounds have been demonstrated as promising broad-spectrum β-lactamase inhibitors to combat β-lactam resistance. Here we report a series of 3-aryl substituted benzoxaborole derivatives, which manifested broad-spectrum inhibition to representative serine-β-lactamases (SBLs) and metallo-β-lactamases (MBLs). The most potent inhibitor 9f displayed an IC50 value of 86 nM to KPC-2 SBL and micromolar inhibitory activity towards other tested enzymes. Cell-based assays further revealed that 9f was able to significantly reduce the MICs of meropenem in clin. isolated KPC-2-producing bacterial strains and it showed no apparent toxicity in HEK293T cells. This study involved multiple reactions and reactants, such as 5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (cas: 1132669-90-9Application In Synthesis of 5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde).

5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (cas: 1132669-90-9) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application In Synthesis of 5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

A synthesis-driven structure revision of plagiochin E, a highly bioactive bisbibenzyl was written by Speicher, Andreas;Groh, Matthias;Zapp, Josef;Schaumloeffel, Anu;Knauer, Michael;Bringmann, Gerhard. And the article was included in Synlett in 2009.Category: ethers-buliding-blocks The following contents are mentioned in the article:

Recently, a bis-bibenzyl named plagiochin E showing remarkable antifungal and antitumor activities was isolated from Marchantia polymorpha, a liverwort. The total synthesis of the proposed structure for plagiochin E and of 2 structurally and biosynthetically related bis-bibenzyls and comparison of the NMR of the synthetic compounds with those of the isolated bis-bibenzyls necessitates a structure revision for plagiochin E. The isolated bis-bibenzyl called plagiochin E proved to be riccardin D. Exemplarily for this metabolite, the stereostructure was investigated, by racemate resolution on a chiral Lux Cellulose-1 phase with HPLC-CD coupling and quantum chem. CD calculations, clearly assigning the P-configuration for the faster and the M-configuration to the slower enantiomer. This study involved multiple reactions and reactants, such as 5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (cas: 1132669-90-9Category: ethers-buliding-blocks).

5-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (cas: 1132669-90-9) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Hybrid Synthetic and Computational Study of an Optimized, Solvent-Free Approach to Curcuminoids was written by Stepanova, Valeria A.;Guerrero, Andres;Schull, Cullen;Christensen, Joshua;Trudeau, Claire;Cook, Joshua;Wolmutt, Kyle;Blochwitz, Jordan;Ismail, Abdelrahman;West, Joseph K.;Wheaton, Amelia M.;Guzei, Ilia A.;Yao, Bin;Kubatova, Alena. And the article was included in ACS Omega in 2022.Recommanded Product: Bisdemethoxycurcumin The following contents are mentioned in the article:

A green and optimized protocol has been developed for the preparation of sym. 1,7-bis(aryl)-1,6-heptadiene-3,5-diones and asym. 2-aryl-6-arylidenecyclohexanones with modified substrate scope and good functional group tolerance. Syntheses proceed smoothly under solvent-free conditions, providing moderate to excellent product yields with a minimal workup procedure. Control experiments, spectroscopic, and computational studies support a mechanism involving the boron-assisted in situ generation of imine intermediates. Crystal structures of three curcuminoids and isolated mechanistic intermediates are reported. The data provide insight for the further development of solvent-free protocols toward diverse curcumin derivatives in the fields of pharmaceutical and synthetic chemistries. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Recommanded Product: Bisdemethoxycurcumin).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: Bisdemethoxycurcumin

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Experimental investigation of rice straw oxidative pyrolysis process in a hot-rod reactor was written by Zhao, Shanhui;Zhang, Yunliang;Su, Yi. And the article was included in Journal of Analytical and Applied Pyrolysis in 2019.Related Products of 2380-78-1 The following contents are mentioned in the article:

In order to improve the utilization of rice straw resources, oxidative pyrolysis of rice straw was investigated in this work. The effects of temperature and oxygen concentration on rice straw oxidative pyrolysis were taken into consideration. Results show that more permanent gases and water were produced under oxidative atmospheres, while the yield of char and tar decreased. The main gaseous products were CO and CO₂ due to the heterogenous oxidation of rice straw/char or secondary reaction of nascent volatiles. Gas chromatograph coupled with a mass spectrometer results show that the oxidative pyrolysis promoted the conversion of primary tar to generate secondary and tertiary tar via in-situ exothermic reaction and active radical attack. Pore structure anal. results of bio-char samples show that oxidative treatment benefited the formation of micro pores and inhibited bio-char thermal annealing at high temperature In general, the oxidative treatment promoted the pyrolysis process and benefited the char modification via in-situ oxidation and formation surface active structure and porosity. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Related Products of 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Related Products of 2380-78-1

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Microwave-assisted extraction of hydroxytyrosol from alperujo and its impact on the stability of mayonnaise was written by Rigane, Ghayth;Ben Salem, Ridha. And the article was included in Journal of the Indian Chemical Society in 2020.Related Products of 2380-78-1 The following contents are mentioned in the article:

Extraction is one of the crucial steps for research and development of plant secondary metabolites. Microwave power and extraction time were selected as extraction parameters of hydroxytyrosol from alperujo. To achieve this goal, the optimization of phys. parameters was carried out by analyzing the obtained extracts using GC-MS apparatus Optimum conditions of microwave-assisted extraction based on maximum levels of responses were medium microwave power with 15 min of alperujo treatment. Maximum levels of hydroxytyrosol were obtained under these conditions (~1.9 g of hydroxytyrosol/kg of alperujo). Furthermore, we have studied the stability of mayonnaise after addition of hydroxytyrosol extract ranging between 65 and195μg by following the changes on free acidity, peroxide value, conjugated dienes as well as content of polyphenols and squalene. This study was conducted for 4 wk and the mayonnaise samples were stored protected from light at room temperature These results showed that 195μg of hydroxytyrosol rich extract may be of great benefit to improve the stability of the mayonnaise against oxidation This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Related Products of 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Related Products of 2380-78-1

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Palladium-catalyzed amination of aryl and heteroaryl tosylates at room temperature was written by Ogata, Tokutaro;Hartwig, John F.. And the article was included in Journal of the American Chemical Society in 2008.Electric Literature of C12H12N2O The following contents are mentioned in the article:

Mild palladium-catalyzed aminations of aryl tosylates and the first aminations of heteroaryl tosylates are described. In the presence of the combination of L₂Pd(0) (L = P(o-tol)₃) and the hindered Josiphos ligand CyPF-t-Bu, a variety of primary alkylamines and arylamines react with both aryl and heteroaryl tosylates at room temperature to form the corresponding secondary arylamines in high yields with complete selectivity for the monoarylamine. These reactions at room temperature occur in many cases with catalyst loadings of 0.1 mol % and 0.01 mol % in one case, constituting the most efficient aminations of aryl tosylates by nearly 2 orders of magnitude. This catalyst is made practical by the development of a convenient method to synthesize the L₂Pd(0) precursor. This complex is stable to air as a solid. In contrast to conventional relative rates for reactions of aryl sulfonates, the reactions of aryl tosylates are faster than parallel reactions of aryl triflates, and the reactions of aryl tosylates are faster than parallel or competitive reactions of aryl chlorides. This study involved multiple reactions and reactants, such as N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2Electric Literature of C12H12N2O).

N-(4-Methoxyphenyl)pyridin-3-amine (cas: 562085-85-2) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Electric Literature of C12H12N2O

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Phenolic profile of oils obtained from “horchata” by-products assisted by supercritical-CO₂ and its relationship with antioxidant and lipid oxidation parameters: Triple TOF-LC-MS-MS characterization was written by Rosello-Soto, Elena;Barba, Francisco J.;Lorenzo, Jose M.;Munekata, Paulo E. S.;Gomez, Belen;Molto, Juan Carlos. And the article was included in Food Chemistry in 2019.Formula: C9H12O3 The following contents are mentioned in the article:

In this study, the effect of different supercritical CO₂ (SC-CO₂) pressures (10-40 MPa) on phenolic compounds extraction in oils obtained from “horchata” byproducts was evaluated, and the results were compared to those obtained after conventional oil extraction (CE). Moreover, the relationship between the individual phenolic compounds and the total antioxidant capacity as well as oil oxidative quality parameters was compared. The phenolic profile and contents were largely influenced by extracting conditions. The main phenolic compound obtained by SC-CO₂ was the isohydroxymatairesinol, particularly at 30 and 40 MPa, while 3-vinylphenol was the predominant compound in oils extracted by CE procedure. Increasing SC-CO₂ extraction pressures enhanced the extraction of phenolic compounds, along with improving the antioxidant capacity and oxidative quality of extracted oil. The principal component anal. indicated that the main phenolic compounds associated with TEAC values were those extracted by SC-CO₂, which were inversely correlated to oxidative indexes. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Formula: C9H12O3).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Formula: C9H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Polyethyleneimine-Modified Polymer as an Efficient Palladium Scavenger and Effective Catalyst Support for a Functional Heterogeneous Palladium Catalyst was written by Yamada, Tsuyoshi;Kobayashi, Yutaka;Ito, Naoya;Ichikawa, Tomohiro;Park, Kwihwan;Kunishima, Kouki;Ueda, Shun;Mizuno, Masahiro;Adachi, Tadashi;Sawama, Yoshinari;Monguchi, Yasunari;Sajiki, Hironao. And the article was included in ACS Omega in 2019.Category: ethers-buliding-blocks The following contents are mentioned in the article:

The polyethyleneimine-modified polymers, polystyrene-divinylbenzene-based (TAs) and polymethacrylate-based polymers (TAm), were used as palladium scavengers to eliminate residual palladium species after palladium on carbon-catalyzed Sonogashira-type coupling reaction. Since both TAs and TAm indicated relatively favorable elimination abilities toward residual palladium species in the reaction mixture, the affinities of TAs and TAm for palladium species were used as supports for palladium catalysts. The TAm-supported palladium catalyst (Pd/TAm) indicated better catalyst properties for the chemoselective hydrogenation compared to those of the corresponding TAs-supported palladium catalyst (Pd/TAs). Aromatic benzyl ethers; aromatic and aliphatic N-Cbzs; and aromatic carbonyl groups were smoothly hydrogenated in the presence of 1-5 mol% of Pd/TAm in MeOH or 2-PrOH. In contrast, the hydrogenation of aromatic ketones was selectively suppressed in morpholine which act as appropriate catalyst poison and solvent. Furthermore, Pd/TAm-catalyzed chemoselective hydrogenation was applicable to continuous-flow reaction. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Category: ethers-buliding-blocks).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Empowering Students with Multidisciplinary Research Experience was written by Waghe, Anil B.;Waghe, Aparna A.. And the article was included in ACS Symposium Series in 2021.COA of Formula: C19H16O4 The following contents are mentioned in the article:

Chem. courses can be trailblazers for breaking the traditional instructional mold for college students. Involving students in course-based undergraduate research experience (CUR) in Organic Chem. helps in developing conceptual understanding and skill development for future careers. The direct impact of our undergraduate research program is improved retention of concepts and intellectual independence. Discovery and collaboration have been a foundation for cluster-based pedagogy at Plymouth State University. The Organic Chem. mini-research project described herein incorporates core concepts and competencies that allow students to work on a challenging problem while experiencing the excitement of scientific discovery. In this chapter, we present how the introduction of a multidisciplinary group research project helped us to demonstrate the relationship between the course materials with core disciplines and enhanced the interest and performance of our students. Assessment of learning and end-of-the-course surveys indicate an increase in the retention of principles taught in the Organic Chem. laboratory course. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0COA of Formula: C19H16O4).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.COA of Formula: C19H16O4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem