Month: November 2022

On March 29, 2021, Huang, Lin; Bismuto, Alessandro; Rath, Simon A.; Trapp, Nils; Morandi, Bill published an article.Formula: C11H10O The title of the article was Ruthenium-Catalyzed Dehydrogenation Through an Intermolecular Hydrogen Atom Transfer Mechanism. And the article contained the following:

The direct dehydrogenation of alkanes is among the most efficient ways to access valuable alkene products. Although several catalysts have been designed to promote this transformation, they have unfortunately found limited applications in fine chem. synthesis. Here, we report a conceptually novel strategy for the catalytic, intermol. dehydrogenation of alkanes using a ruthenium catalyst. The combination of a redox-active ligand and a sterically hindered aryl radical intermediate has unleashed this novel strategy. Importantly, mechanistic investigations have been performed to provide a conceptual framework for the further development of this new catalytic dehydrogenation system. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Formula: C11H10O

The Article related to alkane dehydrogenation ruthenium catalyst reaction mechanism, alkenes, aryl radicals, dehydrogenation, hydrogenation atom transfer, redox-active ligands, General Organic Chemistry: Synthetic Methods and other aspects.Formula: C11H10O

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Washington, Jack B.; Assante, Michele; Yan, Chunhui; McKinney, David; Juba, Vanessa; Leach, Andrew G.; Baillie, Sharon E.; Reid, Marc published an article in 2021, the title of the article was Trialkylammonium salt degradation: implications for methylation and cross-coupling.Recommanded Product: 2-Methylanisole And the article contains the following content:

This study presented a mechanistic degradation anal. of N,N,N-trimethylanilinium salts and highlighted implications for synthetic applications of this important class of salts. Kinetic degradation studies, in both solid and solution phases, had delivered insights into phys. and chem. parameters affecting anilinium salt stability. 1H NMR kinetic anal. of salt degradation had evidenced thermal degradation to Me iodide and parent aniline, consistent with a closed-shell SN2-centered degradative pathway, and Me iodide being key reactive species in applied methylation procedures. Furthermore, effect of halide and non-nucleophilic counterions on salt degradation had been investigated, along with deuterium isotope and solvent effects. New mechanistic insights had enabled investigation of use of trimethylanilinium salts in O-methylation and in improved cross-coupling strategies. Finally, detailed computational studies had helped highlight limitations in current state-of-the-art of solvation modeling of reaction in which bulk medium undergoes exptl. observable changes over reaction timecourse. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Recommanded Product: 2-Methylanisole

The Article related to trialkylammonium salt preparation degradation reaction mechanism dft, methoxy hydrocarbon preparation, alc acid phenol trimethylanilinium salt methylation, General Organic Chemistry: Synthetic Methods and other aspects.Recommanded Product: 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Washington, Jack B.; Assante, Michele; Yan, Chunhui; McKinney, David; Juba, Vanessa; Leach, Andrew G.; Baillie, Sharon E.; Reid, Marc published an article in 2021, the title of the article was Trialkylammonium salt degradation: implications for methylation and cross-coupling.Product Details of 93-04-9 And the article contains the following content:

This study presented a mechanistic degradation anal. of N,N,N-trimethylanilinium salts and highlighted implications for synthetic applications of this important class of salts. Kinetic degradation studies, in both solid and solution phases, had delivered insights into phys. and chem. parameters affecting anilinium salt stability. 1H NMR kinetic anal. of salt degradation had evidenced thermal degradation to Me iodide and parent aniline, consistent with a closed-shell SN2-centered degradative pathway, and Me iodide being key reactive species in applied methylation procedures. Furthermore, effect of halide and non-nucleophilic counterions on salt degradation had been investigated, along with deuterium isotope and solvent effects. New mechanistic insights had enabled investigation of use of trimethylanilinium salts in O-methylation and in improved cross-coupling strategies. Finally, detailed computational studies had helped highlight limitations in current state-of-the-art of solvation modeling of reaction in which bulk medium undergoes exptl. observable changes over reaction timecourse. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Product Details of 93-04-9

The Article related to trialkylammonium salt preparation degradation reaction mechanism dft, methoxy hydrocarbon preparation, alc acid phenol trimethylanilinium salt methylation, General Organic Chemistry: Synthetic Methods and other aspects.Product Details of 93-04-9

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Grochowicz, Marta; Szajnecki, Lukasz; Rogulska, Magdalena published an article in 2022, the title of the article was Crosslinked 4-Vinylpyridine Monodisperse Functional Microspheres for Sorption of Ibuprofen and Ketoprofen.Recommanded Product: 150-78-7 And the article contains the following content:

Nowadays, ibuprofen and ketoprofen are widely used over-the-counter medications to treat inflammation, fever, or pain. Their high consumption and improper disposal cause them to get into the environment and often pollute surface water. In this study, the new polymeric porous microspheres based on 4-vinylpyridine (4VP) are presented as effective sorbents for ibuprofen and ketoprofen preconcentration and removal. The porous microspheres were obtained via seed swelling polymerization with the use of two types of methacrylate crosslinkers, i.e., trimethylolpropane trimethacrylate (TRIM) and 1,4-dimethacryloiloxybenzene (14DMB). Addnl., as a reference sorbent, a copolymer of styrene and divinylbenzene was obtained. Porous structure investigations showed that the microspheres possess a sp. surface area of about 100 m2/g, but noticeable differences were observed in their internal topog. depending on the type of crosslinker used. Moreover, the porous structure of dry and swollen microspheres differs significantly. Swollen copolymers reveal the presence of micropores. The 4VP microspheres are characterized by high thermal stability; their initial decomposition temperature is about 300°C. The performance of the 4VP copolymers as sorbents in aqueous solutions of drugs was evaluated in static and dynamic modes at three pH values of 3, 7, and 11. The highest sorption efficiency was obtained for ibuprofen and ketoprofen in pH 3. Both 4VP copolymers indicate the high sorption capacity in a static sorption as follows: towards ketoprofen of about 40 mg/g whereas towards ibuprofen of about 90 mg/g and 75 mg/g on copolymer crosslinked with trimethylolpropane trimethacrylate and 1,4-dimethacryloiloxybenzene, resp. The recovery of ibuprofen and ketoprofen after dynamic sorption experiments was higher than 90%. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Recommanded Product: 150-78-7

The Article related to ibuprofen ketoprofen vinylpyridine microsphere crosslinking, spe, functional polymers, ibuprofen, ketoprofen, polymeric microspheres, porous polymers, sorption, Pharmaceuticals: Formulation and Compounding and other aspects.Recommanded Product: 150-78-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On February 28, 2005, Mohammadpoor-Baltork, Iraj; Memarian, Hamid R.; Bahrami, Kiumars published an article.Application In Synthesis of Benzyl(4-bromophenyl)sulfane The title of the article was 3-Carboxypyridinium chlorochromate-aluminum chloride – An efficient and inexpensive reagent system for the selective oxidation of sulfides to sulfoxides and sulfones in solution and under microwave irradiation. And the article contained the following:

3-Carboxypyridinium chlorochromate (CPCC) in the presence of aluminum chloride is a very efficient reagent for the selective oxidation of sulfides to sulfoxide and sulfones in solution and under microwave irradiation It is noteworthy that different functional groups including carbon-carbon double bonds, ketones, oximes, aldehydes, ethers, and acetals were tolerated under these reaction conditions. The experimental process involved the reaction of Benzyl(4-bromophenyl)sulfane(cas: 53136-21-3).Application In Synthesis of Benzyl(4-bromophenyl)sulfane

The Article related to sulfoxide sulfone preparation oxidation sulfide carboxypyridinium chlorochromate aluminum chloride, microwave irradiation sulfoxide sulfone preparation oxidation sulfide, General Organic Chemistry: Synthetic Methods and other aspects.Application In Synthesis of Benzyl(4-bromophenyl)sulfane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On February 1, 2009, Padron-Wells, G.; Jarvis, Brandon C.; Jindal, A. K.; Goeckner, M. J. published an article.Application In Synthesis of 2-(2-(Vinyloxy)ethoxy)ethanol The title of the article was Understanding the synthesis of DEGVE pulsed plasmas for application to ultra thin biocompatible interfaces. And the article contained the following:

There is interest in the development of novel surface treatments for biocompatibility and non-fouling behaviors on various surfaces of in vivo devices. Polyethylene glycol thin films have shown promise as non-fouling passivation layers for such devices. Studies of the surface chem. and non-fouling effectiveness of plasma deposited di(ethylene glycol) vinyl ether (DEGVE) films have observed that non-fouling performance is maximized when plasma deposition occurs at low values of average power, (<5 W). [Y. J. Wu, R. B. Timmons, J. S. Jen, Frank E. Molock, Non-fouling surfaces produced by gas phase pulsed plasma polymerization of an ultra low mol. weight ethylene oxide containing monomer, Colloids and Surfaces B: Biointerfaces 18 (2000) 235-248.] Chem. properties of plasma deposited films were directly attributed to the complex interactions occurring within the gas phase. In order to better understand the deposition process, as well as the significance of the conclusions drawn by Wu et al. [Y. J. Wu, R. B. Timmons, J. S. Jen, Frank E. Molock, Non-fouling surfaces produced by gas phase pulsed plasma polymerization of an ultra low mol. weight ethylene oxide containing monomer, Colloids and Surfaces B: Biointerfaces 18 (2000) 235-248.] an investigation of the gas phase behavior in DEGVE pulsed plasma discharges was performed. IR spectra were used to characterize the chem. composition and dissociative behavior of DEGVE plasmas across a range of average powers. This allowed for the construction of a dissociative model of the DEGVE monomer in the plasma discharge. Anal. of the observed dissociative pattern demonstrates the presence of key daughter species which would account for the observations made on deposited DEGVE films by Wu et al. [Y. J. Wu, R. B. Timmons, J. S. Jen, Frank E. Molock, Non-fouling surfaces produced by gas phase pulsed plasma polymerization of an ultra low mol. weight ethylene oxide containing monomer, Colloids and Surfaces B: Biointerfaces 18 (2000) 235-248.]. The experimental process involved the reaction of 2-(2-(Vinyloxy)ethoxy)ethanol(cas: 929-37-3).Application In Synthesis of 2-(2-(Vinyloxy)ethoxy)ethanol

The Article related to diethylene glycol vinyl ether pulsed plasma antifouling coating, Pharmaceuticals: Prosthetics and Medical Goods and other aspects.Application In Synthesis of 2-(2-(Vinyloxy)ethoxy)ethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Lee, Chang-Soo; Chang, Hee Hyun; Jung, Juyeon; Lee, No Ah; Song, Nam Woong; Chung, Bong Hyun published an article in 2012, the title of the article was A novel fluorescent nanoparticle composed of fluorene copolymer core and silica shell with enhanced photostability.COA of Formula: C15H24O2 And the article contains the following content:

A variety of fluorescent nanoparticles have been developed for demanding applications such as optical biosensing and fluorescence imaging in live cells. Silica-based fluorescent nanoparticles offer diverse advantages for biol. applications. For example, they can be used as labeling probes due to their low toxicity, high sensitivity, resolution, and stability. In this research, a new class of highly fluorescent, efficient nanoparticles composed of a newly synthesized poly[di(2-methoxy-5-(2-ethylhexyloxy))-2,7-(9,9-dioctyl-9H-fluorene)] (PDDF) core and a silica shell (designated as PDDF@SiO2) were prepared using a simple reverse micelle method, and their fluorescent properties were evaluated using methods such as single-dot photoluminescence measurements. The enhanced photostability of the particles and their potential applications for bioanal. are discussed in this article. The morphol., size, and fluorescent properties for prepared PDDF@SiO2 nanoparticles were characterized using transmission electron microscopy (TEM), SEM (SEM) and photoluminescence spectroscopy. The prepared particles size, which was approx. 60 nm, resulted in an excellent colloidal stability in a physiol. environment. The photobleaching dynamics, total numbers of emitted photons (TNEP) and statistical measurements of individual nanoparticles were observed using laser scanning fluorescence microscopy to assess the structure and photostability of PDDF@SiO2 nanoparticles. Addnl., PDDF@SiO2 nanoparticles were used in cell toxicity and permeation tests for biol. analyses, demonstrating a great potential for use as powerful, novel materials within the emerging fields of biosensing and biomedical engineering. The experimental process involved the reaction of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene(cas: 146370-51-6).COA of Formula: C15H24O2

The Article related to fluorescent nanoparticle fluorene copolymer silica photostability, Pharmaceuticals: Prosthetics and Medical Goods and other aspects.COA of Formula: C15H24O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On February 7, 2019, Pu, Kanyi; Miao, Qingqing published a patent.Related Products of 146370-51-6 The title of the patent was Polymer nanoparticles for afterglow molecular imaging. And the patent contained the following:

Disclosed herein are semiconducting polymers of formula (I) and polymeric composite materials containing said polymer, where said polymer displays near-IR afterglow luminescence. The polymers of formula I have the following structure, where n, m, o, p, A and R1 to R7 are as defined herein, and r is used to denote a random order to the repeating units. The experimental process involved the reaction of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene(cas: 146370-51-6).Related Products of 146370-51-6

The Article related to polymer semiconductor nanoparticle afterglow luminescence imaging, Pharmaceuticals: Prosthetics and Medical Goods and other aspects.Related Products of 146370-51-6

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On January 3, 2006, Bremmell, Kristen E.; Kingshott, Peter; Ademovic, Zahida; Winther-Jensen, Bjorn; Griesser, Hans J. published an article.Reference of 2-(2-(Vinyloxy)ethoxy)ethanol The title of the article was Colloid Probe AFM Investigation of Interactions between Fibrinogen and PEG-Like Plasma Polymer Surfaces. And the article contained the following:

Interaction forces between surfaces designed to be protein resistant and fibrinogen (Fg) were investigated in phosphate-buffered saline with colloid probe at. force microscopy. The surfaces of the silica probes were coated with a layer of fibrinogen mols. by adsorption from the buffer. The technique of low-power, pulsed AC plasma polymerization was used to make poly(ethylene glycol) (PEG)-like coatings on poly(ethylene terephthalate) by using diethylene glycol vinyl ether as the monomer gas. The degree of PEG-like nature of the films was controlled by use of a different effective plasma power in the chamber for each coating, ranging from 0.6 to 3.6 W. This produced a series of thin films with a different number of ether carbons, as assessed by XPS. The interaction force measurements are discussed in relation to trends observed in the reduction of fibrinogen adsorption, as determined quant. by 125I radio-labeling. The plasma polymer coatings with the greatest protein-repelling properties were the most PEG-like in nature and showed the strongest repulsion in interaction force measurements with the fibrinogen-coated probe. Once forced into contact, all the surfaces showed increased adhesion with the protein layer on the probe, and the strength and extension length of adhesion was dependent on both the applied load and the plasma polymer surface chem. When the medium was changed from buffer to water, the adhesion after contact was eliminated and only appeared at much higher loads. This indicates that the structure of the fibrinogen mols. on the probe is changed from an extended conformation in buffer to a flat conformation in water, with the former state allowing for stronger interaction with the polymer chains on the surface. These experiments underline the utility of aqueous surface force measurements toward understanding protein-surface interactions, and developing nonfouling surfaces that confer a steric barrier against protein adsorption. The experimental process involved the reaction of 2-(2-(Vinyloxy)ethoxy)ethanol(cas: 929-37-3).Reference of 2-(2-(Vinyloxy)ethoxy)ethanol

The Article related to colloid probe fibrinogen polyethylene glycol plasma polymer surface, Pharmaceuticals: Prosthetics and Medical Goods and other aspects.Reference of 2-(2-(Vinyloxy)ethoxy)ethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ruiter, F. A. A.; Sidney, L. E.; Kiick, K. L.; Segal, J. I.; Alexander, C.; Rose, F. R. A. J. published an article in 2020, the title of the article was The electrospinning of a thermo-responsive polymer with peptide conjugates for phenotype support and extracellular matrix production of therapeutically relevant mammalian cells.HPLC of Formula: 929-37-3 And the article contains the following content:

Current cell expansion methods for tissue engineering and regenerative medicine applications rely on the use of enzymic digestion passaging and 2D platforms. However, this enzymic treatment significantly reduces cell quality, due to the destruction of important cell-surface proteins. In addition, culture in 2D results in undesired de-differentiation of the cells caused by the lack of 3D similarity to the natural extracellular matrix (ECM) environment. Research has led to the development of thermo-responsive surfaces for the continuous culture of cells. These thermo-responsive materials properties can be used to passage cells from the surface when the cell culture temperature is reduced. Here we report the development of a PLA/thermo-responsive (PDEGMA) blend 3D electrospun fiber-based scaffold to create an enzymic-free 3D cell culture platform for the expansion of mammalian cells with the desired phenotype for clin. use. Human corneal stromal cells (hCSCs) were used as an exemplar as they have been observed to de-differentiate to an undesirable myo-fibroblastic phenotype when cultured by conventional 2D cell culture methods. Scaffolds were functionalised with a cell adherence peptide sequence GGG-YIGSR by thiol-ene chem. to improve cell adherence and phenotype support. This was obtained by functionalising the thermo-responsive polymer with a thiol (PDEGMA/PDEGSH) by co-polymerization These incorporated thiols react with the norbornene acid functionalised peptide (Nor-GGG-YIGSR) under UV exposure. Presence of the thiol in the scaffold and subsequent peptide attachment on the scaffolds were confirmed by fluorescence labeling, ToF-SIMS and XPS anal. The biocompatibility of the peptide containing scaffolds was assessed by the adhesion, proliferation and immuno-staining of hCSCs. Significant increase in hCSC adherence and proliferation was observed on the peptide containing scaffolds. Immuno-staining showed maintained expression of the desired phenotypic markers ALDH, CD34 and CD105, while showing no or low expression of the undesired phenotype marker a-SMA. This desired expression was observed to be maintained after thermo-responsive passaging and higher when cells were cultured on PLA scaffolds with 10 wt% PDEGMA/4 mol% PDEGS-Nor-GGG-YIGSR. This paper describes the fabrication and application of a first generation, biocompatible peptide conjugated thermo-responsive fibrous scaffold. The ease of fabrication, successful adherence and expansion of a therapeutically relevant cell type makes these scaffolds a promising new class of materials for the application of cell culture expansion platforms in the biomaterials and tissue engineering field. The experimental process involved the reaction of 2-(2-(Vinyloxy)ethoxy)ethanol(cas: 929-37-3).HPLC of Formula: 929-37-3

The Article related to corneal stromal cell thermo responsive polymer phenotype electrospinning, Pharmaceuticals: Prosthetics and Medical Goods and other aspects.HPLC of Formula: 929-37-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem