Category: 150-78-7

On May 9, 2022, Kim, Seulgi; Park, In-Hyeok; Lee, Eunji; Jung, Jong Hwa; Lee, Shim Sung published an article.COA of Formula: C8H10O2 The title of the article was Metallosupramolecules of Pillar[5]arene with Two Flexible Thiopyridyl Arms: A Heterochiral Cyclic Dimer and Organic Guest-Assisted Homochiral Poly-Pseudo-Rotaxanes. And the article contained the following:

The formation of a cyclic dimer complex (1) and a poly-pseudo-rotaxane (2) of a racemic A1/A2-thiopyridyl pillar[5]arene (rac-L) with different chirality is reported. A one-pot reaction of rac-L with HgCl2 afforded a heterochiral cyclic dimer complex, [Hg2(pR-L)(pS-L)Cl4]·8CH2Cl2 (1), in which two Hg2+ atoms and one (pR-L)/(pS-L) enantiomeric pair form a [2:2] metallacycle via a metal coordination-based cyclization. Interestingly, the same reaction in the presence of the linear dinitrile guest, CN(CH2)8CN (G), yielded a one-dimensional poly-pseudo-rotaxane, {[Hg(G@pR-L)Cl2][Hg(G@pS-L)Cl2]}n (2), probably due to the rigidified ligand structure resulting from the dinitrile guest (G) threading. In 2, pR-L and pS-L generate two separated homochiral poly-pseudo-rotaxanes in a crystal. Both products are new members of the pillararene-derivative family. This study improves our understanding of self-assembly in nature and leads to this approach being an engineering tool for the construction of mech. interlocked supramols. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).COA of Formula: C8H10O2

The Article related to thiopyridyl pillararene derivative mercury cyclic dimer pseudo rotaxane preparation, crystal mol structure metallosupramol pillararene pyridylthio mercury dimer rotaxane, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.COA of Formula: C8H10O2

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Shin, Mingyeong; Seo, Sujin; Park, In-Hyeok; Lee, Eunji; Habata, Yoichi; Lee, Shim Sung published an article in 2020, the title of the article was Metallosupramolecules of pillar[5]-bis-trithiacrown including a mercury(II) iodide ion-triplet complex.Product Details of 150-78-7 And the article contains the following content:

A combination of pillar[5]-bis-trithiacrown (L) and Hg(II) halides afforded a monomer complex (Cl–form), a 1-dimensional coordination polymer (Br–form) and a supramol. ion-triplet complex [(I·Hg·I)@L] (I–form). In the ion-triplet complex, the host encapsulates the (I–Hg2+-I-) entity via Hg2+···π and C-H···I- interactions, reflecting geometrical complementarity. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Product Details of 150-78-7

The Article related to mercury halide trithiacrown pillar metallosupramol preparation crystal structure, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Product Details of 150-78-7

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On May 20, 2020, Bao, Xia-Zhen; Wang, Qi; Ren, Xiao-Rong; Dai, Fang; Zhou, Bo published an article.Name: 1,4-Dimethoxybenzene The title of the article was A hydrogen peroxide-activated Cu(II) pro-ionophore strategy for modifying naphthazarin as a promising anticancer agent with high selectivity for generating ROS in HepG2 cells over in L02 cells. And the article contained the following:

Targeting redox vulnerability of cancer cells by pro-oxidants capable of generating reactive oxygen species (ROS) has surfaced as an important anticancer strategy. Due to the intrinsic narrow therapeutic window and other dangerous side effects of ROS generation, it is highly needed and challenging to develop pro-oxidative anticancer agents (PAAs) with high selectivity for generating ROS in cancer cells. Herein we report a hydrogen peroxide (H2O2)-activated Cu(II) pro-ionophore strategy to develop naphthazarin (Nap) as such type of PAAs based on the H2O2-mediated conversion of boronate to free phenol. The boronate-protected Nap (PNap) can exploit increased levels of H2O2 in HepG2 cells to in situ release Nap followed by its efflux via conjugation with reduced glutathione (GSH), allowing that the Nap-GSH adduct works as a Cu(II) ionophore to induce continuously GSH depletion via a reduction-dependent releasing of Cu(I) by GSH. This strategy endows PNap with the unprecedented ability to hit multi-redox characteristics (increased levels of H2O2, GSH and copper) of HepG2 cells, leading to ROS generation preferentially in HepG2 cells along with their selective death. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Name: 1,4-Dimethoxybenzene

The Article related to hydrogen peroxide copper proionophore naphthazarin preparation cancer, copper, glutathione, hydrogen peroxide, ionophore, reactive oxygen species, Pharmacology: Effects Of Neoplasm Inhibitors and Cytotoxic Agents and other aspects.Name: 1,4-Dimethoxybenzene

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On July 29, 2020, Kang, Chengjun; Zhang, Zhaoqiang; Wee, Vanessa; Usadi, Adam K.; Calabro, David C.; Baugh, Lisa Saunders; Wang, Shun; Wang, Yuxiang; Zhao, Dan published an article.Electric Literature of 150-78-7 The title of the article was Interlayer Shifting in Two-Dimensional Covalent Organic Frameworks. And the article contained the following:

Layer-stacking structures are very common in two-dimensional covalent organic frameworks (2D COFs). While their structures are normally determined under solvent-free conditions, the structures of solvated 2D COFs are largely unexplored. We report herein the in situ determination of solvated 2D COF structures, which exhibit an obvious difference as compared to that of the same COF under dried state. Powder X-ray diffraction (PXRD) data analyses, computational modeling, and Pawley refinement indicate that the solvated 2D COFs experience considerable interlayer shifting, resulting in new structures similar to the staggered AB stacking, namely, quasi-AB-stacking structures, instead of the AA-stacking structures that are usually observed in the dried COFs. We attribute this interlayer shifting to the interactions between COFs and solvent mols., which may weaken the attraction strength between adjacent COF layers. D. functional theory (DFT) calculations confirm that the quasi-AB stacking is energetically preferred over the AA stacking in solvated COFs. All four highly crystalline 2D COFs examined in the present study exhibit considerable interlayer shifting upon solvation, implying the universality of the solvent-induced interlayer stacking rearrangement in 2D COFs. These findings prompt re-examination of the 2D COF structures in solvated state and suggest new opportunities for the applications of COF materials under wet conditions. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Electric Literature of 150-78-7

The Article related to interlayer shifting two dimensional covalent organic framework, Physical Properties of Synthetic High Polymers: Polymer Structure and other aspects.Electric Literature of 150-78-7

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On July 31, 2022, Earley, J. D.; Zieleniewska, A.; Ripberger, H. H.; Shin, N. Y.; Lazorski, M. S.; Mast, Z. J.; Sayre, H. J.; McCusker, J. K.; Scholes, G. D.; Knowles, R. R.; Reid, O. G.; Rumbles, G. published an article.Safety of 1,4-Dimethoxybenzene The title of the article was Ion-pair reorganization regulates reactivity in photoredox catalysts. And the article contained the following:

Cyclometalated and polypyridyl complexes of d6 metals are promising photoredox catalysts, using light to drive reactions with high kinetic or thermodn. barriers via the generation of reactive radical intermediates. However, while tuning of their redox potentials, absorption energy, excited-state lifetime and quantum yield are well-known criteria for modifying activity, other factors could be important. Here we show that dynamic ion-pair reorganization controls the reactivity of a photoredox catalyst, [Ir[dF(CF3)ppy]2(dtbpy)]X. Time-resolved dielec.-loss experiments show how counter-ion identity influences excited-state charge distribution, evincing large differences in both the ground- and excited-state dipole moment depending on whether X is a small associating anion (PF6-) that forms a contact-ion pair vs. a large one that either dissociates or forms a solvent-separated pair (BArF4-). These differences correlate with the reactivity of the photocatalyst toward both reductive and oxidative electron transfer, amounting to a 4-fold change in selectivity toward oxidation vs. reduction These results suggest that ion pairing could be an underappreciated factor that modulates reactivity in ionic photoredox catalysts. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Safety of 1,4-Dimethoxybenzene

The Article related to iridium complex photoredox catalyst counter ion effect, Physical Organic Chemistry: Other Reactions, Processes, and Spectra and other aspects.Safety of 1,4-Dimethoxybenzene

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On September 5, 2022, Cha, Youngho; Kim, Tae-Kyoung; Lee, Jaewon; Kim, Taeyeon; Hong, Ae-Jung; Zoh, Kyung-Duk published an article.Computed Properties of 150-78-7 The title of the article was Degradation of iopromide during the UV-LED/chlorine reaction: Effect of wavelength, radical contribution, transformation products, and toxicity. And the article contained the following:

Three different UV-LED wavelengths (265, 310, and 365 nm) were used in the UV-LED/chlorine reaction to investigate the degradation mechanism of iopromide (IPM) at different wavelengths, a representative iodinated contrast media compound The degradation rate (k’IPM) increased from pH 6-8 at 265 nm, but, decreased as the pH increased up to 9 at 310 nm and 365 nm. Radical scavenging experiments showed that reactive chlorine species (RCS) are the dominant radical species at all wavelengths, but a higher contribution of OH· was observed at lower pH and longer wavelengths. The contribution of RCS decreased but the contribution of OH· increased as the wavelength increased. Among RCS, the largest contribution was found to be ClO·. Total nine transformation products (TPs) were identified by LC-QTOF-MS during the UV-LED/chlorine reaction at 265 nm. Based on the identified TPs and their time profiles, we proposed a degradation pathway of IPM during UV-LED/chlorine reaction. The Microtox test using V. fischeri showed that no significant increase in toxicity was observed at all wavelengths. The synergistic effect of UV-LED and chlorine was greater at a higher wavelength by the elec. efficiency per order (EEO) calculation The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Computed Properties of 150-78-7

The Article related to iopromide chlorine reaction radical scavenging experiment, hydroxyl radical, microtox test, reactive chlorine species (rcs), transformation products (tps), uv-led, Waste Treatment and Disposal: Chemical Treatment Of Aqueous Wastes and other aspects.Computed Properties of 150-78-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On May 15, 2021, Li, Mingxue; Mei, Qiong; Wei, Bo; An, Zexiu; Sun, Jianfei; Xie, Ju; He, Maoxia published an article.Category: ethers-buliding-blocks The title of the article was Mechanism and kinetics of ClO·-mediated degradation of aromatic compounds in aqueous solution: DFT and QSAR studies. And the article contained the following:

The action of ClO· is more prominent than HO· and Cl· in the advanced oxidation degradation of some pollutants. However, studies on the pollutant degradation mechanism and kinetics by ClO· are limited. In this study, 43 different kind of aromatic compounds which are important anthropogenic and natural water pollutants were selected as models to investigate their ClO· oxidation mechanism and kinetics computationally. The results showed that radical adduct formation (RAF) rather than single electron transfer (SET) reaction was prominent in ClO·-initiated reactions of aromatic compounds In subsequent reactions of the ClO-adduct, the Cl end of the -OCl moiety shifted to the benzene ring, which was the key to hydroxylation and chlorination of aromatic compounds by ClO·. The calculated ClO· initiated reaction rate constants (k·ClO) of aromatic compounds were 102-1010 M-1 s-1. ClO· was highly reactive to phenolates, anilines and alkoxy/hydroxyl aromatic compounds Upon the deprotonation of phenol to phenolate, the k·ClO value increased by 4 orders of magnitude. The k·ClO values of alkoxybenzenes were higher for compounds with shorter alkyl side chains and more alkoxy substituents. The k·ClO increased for anilines with longer alkyl side chains. The k·ClO quant. structure-activity relationships (QSARs) models were developed to predict the reactivity of ClO· to complex aromatic compounds in aquatic systems. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Category: ethers-buliding-blocks

The Article related to density functional theory degradation chlorine oxide radical wastewater treatment, Waste Treatment and Disposal: Chemical Treatment Of Aqueous Wastes and other aspects.Category: ethers-buliding-blocks

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On July 16, 2021, Kolb, Simon; Ahlburg, Nils L.; Werz, Daniel B. published an article.Formula: C8H10O2 The title of the article was Friedel-Crafts-Type Reactions with Electrochemically Generated Electrophiles from Donor-Acceptor Cyclopropanes and -Butanes. And the article contained the following:

A general electrochem. method to functionalize donor-acceptor (D-A) cyclopropanes and -butanes with arenes utilizing Friedel-Crafts-type reactivity is discussed. The catalyst-free strategy relies on the direct anodic oxidation of the strained carbocycles, which leads after C(sp3)-C(sp3) cleavage to radical cations that act as electrophiles for the arylation reaction. Broad reaction scopes in regard to cyclopropanes, cyclobutanes, and aromatic reaction partners are presented. Addnl., a plausible electrolysis mechanism is proposed. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Formula: C8H10O2

The Article related to cyclopropane cyclobutane arene electrochem friedel crafts type reaction, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: General and other aspects.Formula: C8H10O2

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Ether | (C2H5)2O – PubChem

On August 6, 2021, Sukowski, Verena; Jia, Wen-Liang; van Diest, Rianne; van Borselen, Manuela; Fernandez-Ibanez, M. Angeles published an article.Quality Control of 1,4-Dimethoxybenzene The title of the article was S,O-Ligand-Promoted Pd-Catalyzed C-H Olefination of Anisole Derivatives. And the article contained the following:

The C-H olefination of substituted anisole derivatives by a Pd/S,O-ligand catalyst is reported. The reaction proceeds under mild conditions with a broad range of substituted aryl ethers bearing both electron donating and withdrawing substituents at ortho, meta and para positions. Aryl ethers are used as limiting reagents and good yields and site selectivities are observed The methodol. is operationally simple and can be performed under aerobic conditions. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Quality Control of 1,4-Dimethoxybenzene

The Article related to anisole olefination palladium catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: General and other aspects.Quality Control of 1,4-Dimethoxybenzene

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On October 7, 2020, Tuo, Wei; Sun, Yan; Lu, Shuai; Li, Xiaopeng; Sun, Yao; Stang, Peter J. published an article.Product Details of 150-78-7 The title of the article was Pillar[5]arene-Containing Metallacycles and Host-Guest Interaction Caused Aggregation-Induced Emission Enhancement Platforms. And the article contained the following:

Coordination-driven Pt metallacycles have shown potential in controllable modular self-assembly, which has made a vital contribution to biomedicine, catalysis, and multiresponsive materials. Herein, pillar[5]arene units were integrated into one skeleton through coordination-driven self-assembly, resulting in the formation of a hexagonal Pt(II) metallacycle decorated with six pillar[5]arenes. The host-guest interactions of the as-prepared metallacycle (pillar[5]arenes as hosts) and 1-butyl-4-[4-(diphenylamino)styryl]pyridinium (guest) were investigated. The metallacycle was found to facilitate the coaggregation between the guests and pillar[5]arenes through a synergistic effect, thus engendering a sharp increase in fluorescence intensity. The resultant aggregate was investigated by DLS and TEM. Our studies imply that the pillar[5]arene-containing metallacycle can serve as a potential platform for realizing emission enhancement effects. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Product Details of 150-78-7

The Article related to pillararene containing metallacycle host guest interaction, aggregation induced emission enhancement, Physical Organic Chemistry: Other Reactions, Processes, and Spectra and other aspects.Product Details of 150-78-7

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem