Category: ethers-buliding-blocks

Solvothermal Synthesis of CuFe₂O₄@rGO: Efficient Catalyst for C-O Cross Coupling and N-arylation Reaction under Ligand-Free Condition was written by Nakhate, Akhil V.;Yadav, Ganapati D.. And the article was included in ChemistrySelect in 2017.Category: ethers-buliding-blocks This article mentions the following:

The copper ferrite supported reduced graphene oxide (CuFe₂O₄@rGO) synthesis by solvothermal process has been reported. The prepared CuFe₂O₄@rGO catalyst was used for C-O and C-N cross coupling reactions. The activity of the catalyst was compared with com. Cu₂O, CuO and CuFe₂O₄ for C-O cross coupling of iodobenzene with phenol. The CuFe₂O₄@rGO was the best catalyst with 97% conversion towards iodobenzene at 100 °C under ligand free condition which is otherwise normally used. The virgin and five times reused CuFe₂O₄@rGO catalyst was characterized by XRD, SEM, FTIR, TEM, N2-adsorption desorption isotherm, XPS and TGA anal. The effect of solvent, nature of base, speed of agitation, mole ratio, catalyst loading and temperature were studied for phenol and iodobenzene reaction and its activity was further explored in N-arylation of indole with iodobenzene. The best conversion and yield were achieved at 100 °C at 1×10-3 g/cm³ catalyst loading. Notably, CuFe₂O₄@rGO was reusable without any loss of catalytic activity for five recycles. Reaction mechanism and kinetics are also presented. The overall process is novel and green. In the experiment, the researchers used many compounds, for example, 1-(4-(4-Methoxyphenoxy)phenyl)ethanone (cas: 54916-28-8Category: ethers-buliding-blocks).

1-(4-(4-Methoxyphenoxy)phenyl)ethanone (cas: 54916-28-8) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

New crown compounds derived from 1,2-bis(2-hydroxybenzyl)benzene (II): bisaryl crowns was written by Lee, Woo Young;Jung, Jae Do;Park, Chang Hee;Sim, Wonbo. And the article was included in Bulletin of the Korean Chemical Society in 1990.Related Products of 60221-37-6 This article mentions the following:

The reaction of 1,2-(2-HOC₆H₄CH₂)₂C₆H₄ (I) in base with 4-MeC₆H₄SO₃CH₂(CH₂OCH₂)_nOR (R = tetrahydropyranyl; n = 0-3), deprotection of the bis-condensation product to give the diol, tosylation of the free hydroxyls of the diol, and condensation of the ditosylate in base with I afforded bisaryl corand II. Oxidation of the benzylic positions of II furnished novel aromatic corands containing carbonyl functions. In the experiment, the researchers used many compounds, for example, 2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol (cas: 60221-37-6Related Products of 60221-37-6).

2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol (cas: 60221-37-6) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Related Products of 60221-37-6

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Cinnamonitrile Adjuvants Restore Susceptibility to β-Lactams against Methicillin-Resistant Staphylococcus aureus was written by Speri, Enrico;Kim, Choon;De Benedetti, Stefania;Qian, Yuanyuan;Lastochkin, Elena;Fishovitz, Jennifer;Fisher, Jed F.;Mobashery, Shahriar. And the article was included in ACS Medicinal Chemistry Letters in 2019.Recommanded Product: 3-Formyl-2-methoxyphenylboronic acid This article mentions the following:

β-Lactams are used routinely to treat Staphylococcus aureus infections. However, the emergence of methicillin-resistant S. aureus (MRSA) renders them clin. precarious. We describe a class of cinnamonitrile adjuvants that restore the activity of oxacillin (a penicillin member of the β-lactams) against MRSA. The lead adjuvants were tested against six important strains of MRSA, one vancomycin-intermediate S. aureus (VISA) strain, and one linezolid-resistant S. aureus strain. Five compounds out of 84 total compounds showed broad potentiation. At 8 μM (E)-3-(5-(3,4-dichlorobenzyl)-2-(trifluoromethoxy)phenyl)-2-(methylsulfonyl)acrylonitrile (26) potentiated oxacillin with a >4000-fold reduction of its MIC (from 256 to 0.06 mg·L^-1). This class of adjuvants holds promise for reversal of the resistance phenotype of MRSA. In the experiment, the researchers used many compounds, for example, 3-Formyl-2-methoxyphenylboronic acid (cas: 480424-49-5Recommanded Product: 3-Formyl-2-methoxyphenylboronic acid).

3-Formyl-2-methoxyphenylboronic acid (cas: 480424-49-5) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Recommanded Product: 3-Formyl-2-methoxyphenylboronic acid

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Speciation Analysis and Thermodynamic Criteria of Solvated Ionic Liquids: Ionic Liquids or Superconcentrated Solutions? was written by Arai, Nana;Watanabe, Hikari;Nozaki, Erika;Seki, Shiro;Tsuzuki, Seiji;Ueno, Kazuhide;Dokko, Kaoru;Watanabe, Masayoshi;Kameda, Yasuo;Umebayashi, Yasuhiro. And the article was included in Journal of Physical Chemistry Letters in 2020.HPLC of Formula: 112-49-2 This article mentions the following:

Lithium-glyme solvate ionic liquids (Li-G SILs) and super-concentrated electrolyte solutions (SCESs) are expected as a promising electrolyte for the next generation lithium secondary batteries. The former consists of only the oligoether glyme solvated lithium ion and its counter anion and the latter contains no full solvated Li⁺ ion by the solvents due to the extremely high Li salt concentration Although both of them are similar with each other, it is still unclear that both should be room-temperature ionic liquids (RTILs). To reveal the distinct definition for them, speciation analyses were performed to the Li-G SIL and the aqueous SCES to evaluate the free solvent concentration in these solutions with a new Raman/IR spectral anal. technique called complementary least square anal. (CLSA). Furthermore, from a thermodn. point of views, we investigated the solvent activity/activity coefficient in the gas phase equilibrated with sample solutions and found they can be a good criterion for SILs. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2HPLC of Formula: 112-49-2).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.HPLC of Formula: 112-49-2

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

N-(2-Benzoylphenyl)-L-tyrosine PPARγ Agonists. 2. Structure-Activity Relationship and Optimization of the Phenyl Alkyl Ether Moiety was written by Collins, Jon L.;Blanchard, Steven G.;Boswell, G. Evan;Charifson, Paul S.;Cobb, Jeff E.;Henke, Brad R.;Hull-Ryde, Emily A.;Kazmierski, Wieslaw M.;Lake, Debra H.;Leesnitzer, Lisa M.;Lehmann, Juergen;Lenhard, James M.;Orband-Miller, Lisa A.;Gray-Nunez, Yolanda;Parks, Derek J.;Plunkett, Kelli D.;Tong, Wei-Qin. And the article was included in Journal of Medicinal Chemistry in 1998.Application of 3929-47-3 This article mentions the following:

We previously reported the identification of (2S)-((2-benzoylphenyl)amino)-3-{4-[2-(5-methyl-2-phenyloxazol-4-yl)ethoxy]phenyl}propanoic acid (I) (PPARγ pK_i = 8.94, PPARγ pEC₅₀ = 9.47) as a potent and selective PPARγ agonist. We now report the expanded structure-activity relationship around the Ph alkyl ether moiety by pursuing both a classical medicinal chem. approach and a solid-phase chem. approach for analog synthesis. The solution-phase strategy focused on evaluating the effects of oxazole and Ph ring replacements of the 2-(5-methyl-2-phenyloxazol-4-yl)ethyl side chain of I with several replacements providing potent and selective PPARγ agonists with improved aqueous solubility Specifically, replacement of the Ph ring of the phenyloxazole moiety with a 4-pyridyl group to give (2S)-((2-benzoylphenyl)amino)-3-{4-[2-(5-methyl-2-pyridin-4-yloxazol-4-yl)ethoxy]phenyl}propionic acid (PPARγ pK_i = 8.85, PPARγ pEC₅₀ = 8.74) or a 4-methylpiperazine to give (2S)-((2-benzoylphenyl)amino)-3-(4-{2-[5-methyl-2-(4-methylpiperazin-1-yl)thiazol-4-yl]ethoxy}phenyl)propionic acid (PPARγ pK_i = 8.66, PPARγ pEC₅₀ = 8.89) provided two potent and selective PPARγ agonists with increased solubility in pH 7.4 phosphate buffer and simulated gastric fluid as compared to I. The second strategy took advantage of the speed and ease of parallel solid-phase analog synthesis to generate a more diverse set of Ph alkyl ethers which led to the identification of a number of novel, high-affinity PPARγ ligands (PPARγ pK_i‘s 6.98-8.03). The combined structure-activity data derived from the two strategies provide valuable insight on the requirements for PPARγ binding, functional activity, selectivity, and aqueous solubility In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Application of 3929-47-3).

3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Application of 3929-47-3

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Double N,B-Type Bidentate Boryl Ligands Enabling a Highly Active Iridium Catalyst for C-H Borylation was written by Wang, Guanghui;Xu, Liang;Li, Pengfei. And the article was included in Journal of the American Chemical Society in 2015.Reference of 365564-07-4 This article mentions the following:

Boryl ligands hold promise in catalysis due to their very high electron-donating property. In this communication double N,B-type boryl anions were designed as bidentate ligands to promote an sp² C-H borylation reaction. A sym. pyridine-containing tetraaminodiborane(4) compound was readily prepared as the ligand precursor that could be used, in combination with [Ir(OMe)(COD)]₂, to in situ generate a highly active catalyst for a broad range of (hetero)arene substrates including highly electron-rich and/or sterically hindered ones. This work provides the 1st example of a bidentate boryl ligand in supporting homogeneous organometallic catalysis. In the experiment, the researchers used many compounds, for example, 2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 365564-07-4Reference of 365564-07-4).

2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 365564-07-4) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Reference of 365564-07-4

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Organophotoredox-catalyzed cyanoalkylation of 1,4-quinones was written by Kulthe, Arun D.;Jaiswal, Sunidhi;Golagani, Durga;Mainkar, Prathama S.;Akondi, Srirama Murthy. And the article was included in Organic & Biomolecular Chemistry in 2022.Quality Control of 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione This article mentions the following:

A visible-light-induced metal-free cyanoalkylation of 1,4-quinones under mild and redox-neutral conditions to afford desired cyanoalkylated quinones I [R = H, Ph, Bn, etc.; R¹ = H, Me, OH, etc.; X = CHR², CH₂, O; R² = 4-t-BuPh, Bu, etc.] was described. This reaction proceeded at room temperature without the need of extra base or additive and was suitable for a variety of 1,4-quinones and differently substituted cyclobutanone oxime esters. Further transformation of cyano functionality to tetrazole and amine had also been demonstrated to showcase the advantage of this method to prepare drug-like mols. In the experiment, the researchers used many compounds, for example, 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7Quality Control of 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione).

2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Quality Control of 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Isatogens. V. Hydroxyhydroquinol derivatives of the isatogen series was written by Ruggli, Paul;Leonhardt, Werner. And the article was included in Helvetica Chimica Acta in 1924.Product Details of 5367-32-8 This article mentions the following:

Thiele’s reaction in which a hydroxhydroquinol is formed from p-C₆H₄O₂ and Ac₂O containing some H₂SO₄ (Ber. 31, 1247) may be applied to the isatogen series. Thus when 3 g. 6-nitro-2-phenylisatogen is added to 15 cc. Ac₂O containing 0.25 cc. concentrated H₂SO₄ and warmed to 50° for 15 min., there results, in addition to 1 g. of a by-product to be described later, 2 g. (45%) of 1,3,5-triacetoxy-2-phenyl-6-nitroindole (I), bright yellow, m. 194-5°. Aqueous alkali gives a deep red solution; concentrated H₂SO₄ gives a deep violet solution containing III. Boiling 2 g. I with 20 cc. EtOH and 1.25 cc. concentrated HCl about 30 min. gives the 1,3-Ac₂ derivative, orange-yellow, m. 214-5° (70% yield); with concentrated H₂SO₄ it gives the same violet solution as I. The 5-chloroacetoxy derivative is yellow and m. 156-8° (decomposition). The 5-MeO derivative (II), greenish yellow, m. 221-2°, results by the action of CH₂N₂. Concentrated H₂SO₄ reacts with I to give 2-phenyl-5-hydroxy-6-nitro-3-ketoindolenine (III), brick-red, m. 188°; very dilute alkali gives an emerald-green solution, from which black flakes soon sep. A large excess of H₂NOH.HCl gives the oxime (IV), red, m. 280° (decomposition), which gives a Me ether, dark red, m. 172°, with Me₂SO₄; this with Ac₂O-H₂SO₄ gives the 5-Ac derivative, brick-red, m. 152°. The 5-MeO derivative (V), dark red, m. 205°, results by the action of concentrated H₂SO₄ upon II; warmed with aqueous alkali, it gradually decomposes Ac₂O regenerates II. The oxime (VI), orange-red, m. 263-4°, whose Me ether is deep red and m. 157°; this is also formed from IV and CH₂N₂. Oxidation of VI in AcOH with CrO₃ gives 2-phenyl-3,6-dinitro-5-methoxyindole, bright yellow, m. 303-6° (decomposition), in 40-45% yields, while oxidation of V gives 4-nitro-5-methoxybenzoylanthranilic acid (VII), golden yellow, m. 272°. Heated with H₃PO₄ up to 170°, VII gives 2-amino-4-nitro-5-methoxybenzoic acid, violet-black, m. 217-8°; the aqueous solution is orange-red. 4-Amino-5-methoxybenzoylanthranilic acid, decompose 200°, results by the reduction of the Na salt of VII by H and Ni; the 4-Ac derivative decomposes 275°. The reduction of the diazo compound yields 5-methoxybenzoylanthranilic acid, m. 200°, which was synthesized from 2-nitro-5-methoxytoluene, yellow, m. 50°, through reduction with Sn and HCl and subsequent treatment with NaOH and BzCl, yielding the 2-benzoylamino-5-methoxytoluene, m. 200°, and oxidation with KMnO₄. The 3-methoxybenzoylanthranilic acid, prepared in a similar manner, m. 204.5°, but depressed the m. p. of the 5-derivative 25°. 2-Nitro-6-methoxytoluene, yellow, m. 52°. 2-Benzoylamino-6-methoxytoluene, m. 177°. 6-Methoxybenzoylanthranilic acid, m. 120°. The action of SnCl₂ in AcOH saturated with HCl upon II gives 2-phenyl-3-acetoxy-5-methoxy-6-aminoindole, m. 212°; with Ac₂O and concentrated H₂SO₄ this forms 1-acetyl-2-phenyl-3-acetoxy-5-methoxy-6-diacetaminoindole, m. 220°. Me isatogenate treated with Ac₂O and H₂SO₄ gives a yellow compound, C₁₆H₁₅O₈N, m. 193-5°, which may be the corresponding triacetoxyhydroquinol derivative In the experiment, the researchers used many compounds, for example, 3-Methyl-4-nitroanisole (cas: 5367-32-8Product Details of 5367-32-8).

3-Methyl-4-nitroanisole (cas: 5367-32-8) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Product Details of 5367-32-8

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Reduction of Synthetic Ubiquinone QT Catalyzed by Bovine Mitochondrial Complex I Is Decoupled from Proton Translocation was written by Okuda, Kenji;Murai, Masatoshi;Aburaya, Shunsuke;Aoki, Wataru;Miyoshi, Hideto. And the article was included in Biochemistry in 2016.SDS of cas: 605-94-7 This article mentions the following:

We previously succeeded in site-specific chem. modifications of the inner part of the quinone binding pocket of bovine mitochondrial complex I through ligand-directed tosylate (LDT) chem. using specific inhibitors as high-affinity ligands for the enzyme [Masuya, T., et al. (2014) Biochem.53, 2304-2317, 7816-7823]. To investigate whether a short-chain ubiquinone, in place of these specific inhibitors, serves as a ligand for LDT chem., we herein synthesized a LDT reagent QT possessing ubiquinone scaffold and performed LDT chem. with bovine heart submitochondrial particles (SMP). Detailed proteomic analyses revealed that QT properly guides the tosylate group into the quinone binding pocket and transfers a terminal alkyne to nucleophilic amino acids His150 and Asp160 in the 49 kDa subunit. This result clearly indicates that QT occupies the inner part of the quinone binding pocket. Nevertheless, we noted that QT is a unique electron acceptor from complex I distinct from typical short-chain ubiquinones such as ubiquinone-1 (Q₁) for several reasons; for example, QT reduction in NADH-QT oxidoredn. was almost completely insensitive to quinone-site inhibitors (such as bullatacin and piericidin A), and this reaction did not produce a membrane potential. On the basis of detailed comparisons of the electron transfer features between QT and typical short-chain quinones, we conclude that QT may accept electrons from an N2 cluster at a position different from that of typical short-chain quinones because of its unique side-chain structure; accordingly, QT reduction is unable to induce putative structural changes inside the quinone binding pocket, which are critical for driving proton translocation. Thus, QT is the first ubiquinone analog, to the best of our knowledge, the catalytic reduction of which is decoupled from proton translocation through the membrane domain. Implications for mechanistic studies on QT are also discussed. In the experiment, the researchers used many compounds, for example, 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7SDS of cas: 605-94-7).

2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.SDS of cas: 605-94-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

1,2,4-dithiazolidines; synthesis, antibacterial and antifungal activity was written by Deohate, Pradip P.;Berad, B. N.. And the article was included in Chemistry: An Indian Journal in 2004.Related Products of 57179-35-8 This article mentions the following:

3,5-Diphenylimino-4-alkylbenzylidene amidino-1,2,4-dithiazolidines, e.g., I, have been obtained by the basification of their hydrochlorides, which were prepared by efficient method of interaction of N-phenyl-S-chloro isothiocarbamoyl chloride and 1-(substituted) alkylbenzylidene amidino-3-Ph thiocarbamides. The latter were synthesized by the condensation of 1-amidino-3-Ph thiocarbamide and different aliphatic and aromatic aldehydes. 3,5-Diphenylimino-4-alkylbenzylidene amidino-1,2,4-dithiazolidines underwent acylation to afford monoacetyl derivatives, and on reaction with sodium nitrite in acidic medium afforded mononitroso derivatives The title compounds were assayed for their antibacterial and antifungal activity against gram pos. as well as gram neg. microorganisms. In the experiment, the researchers used many compounds, for example, 3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8Related Products of 57179-35-8).

3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Related Products of 57179-35-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem