Category: ethers-buliding-blocks

Characterization studies of tar-containing wastewater for bio-energy and chemical production was written by Wang, W. P.;Wu, S. B.;Zhao, J. Q.;Hua, W.. And the article was included in Journal of Biobased Materials and Bioenergy in 2018.Recommanded Product: 2380-78-1 The following contents are mentioned in the article:

The compositions and physicochem. properties of organic condensates pollutant in tar-containing wastewater, which was obtained from gas purification process of biomass gasification, were preliminarily investigated. The thermal decomposition characteristics of dissolved solids (DS) derived from tar-containing wastewater were studied by thermal gravimetric anal. (TGA) and pyrolyzer coupled with gas chromatograph/mass spectrometry (Py-GC/MS). The results showed that: more than forty kinds of organic compounds in such pollutant were detected by GC/MS, including phenols, ketones and furans; the lower viscosity of concentrated DS was conducive to its recycling; the decomposition of DS could be divided into three stages (dewater stage, volatile releasing stage and degradation of residues stage) and the final residue was 39.00%. The thermal decomposition products derived from DS mainly consisted of aromatic compounds, pyrans and small mol. acids. The phenolic compounds were the most abundant, contributing over 32% of the total compounds detected. These compounds showed great potential on fuel industry application and intermediates generation. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Recommanded Product: 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: 2380-78-1

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Phytochemical properties and functional characteristics of wild turmeric (Curcuma aromatica) fermented with Rhizopus oligosporus was written by Lim, Juho;Nguyen, Thi Thanh Hanh;Pal, Kunal;Gil Kang, Choon;Park, Chanho;Kim, Seung Wook;Kim, Doman. And the article was included in Food Chemistry: X in 2022.Reference of 33171-05-0 The following contents are mentioned in the article:

This study investigated the effect of solid-state fermentation of wild turmeric (Curcuma aromatica) with Rhizopus oligosporus, a common fungus found in fermented soy tempeh, on phytochem. and biol. properties. Ultra-performance liquid chromatog.-tandem mass spectrometry showed that fermented wild turmeric has higher concentrations of curcumin, demethoxycurcumin, bisdemethoxycurcumin, phenolic compounds and total flavonoid-curcuminoid after fermentation for 1-, 3-, and 5-day relative to non-fermented turmeric. The L-carnitine content reached 242μg g-1 extract after fermentation for 7-day. Wild turmeric had 1.47- and 2.25-fold increases in ORAC and FRAP, resp., after 3-day fermentation The inhibitory effects of fermented wild turmeric on lipid accumulation from 3T3-L1 cells, nitric oxide production from lipopolysaccharide-stimulated RAW264.7 murine macrophages, and melanin formation by B16F10 mouse melanoma cells with α-MSH increased 1.08-, 1.44-, and 1.52-fold, resp., after 3-day fermentation Based on these results, fermented wild turmeric product can be used as a functional ingredient in the cosmeceutical and nutraceutical industries. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Reference of 33171-05-0).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Reference of 33171-05-0

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The functional potential of nine Allium species related to their untargeted phytochemical characterization, antioxidant capacity and enzyme inhibitory ability was written by Rocchetti, Gabriele;Zhang, Leilei;Bocchi, Serena;Giuberti, Gianluca;Ak, Gunes;Elbasan, Fevzi;Yildiztugay, Evren;Ceylan, Ramazan;Picot-Allain, Marie Carene Nancy;Mahomoodally, Mohamad Fawzi;Lucini, Luigi;Zengin, Gokhan. And the article was included in Food Chemistry in 2022.Reference of 33171-05-0 The following contents are mentioned in the article:

In this study, the aerial parts and bulbs of nine Allium species were investigated for their functional phytochem. profile, in vitro antioxidant activities, acetylcholinesterase (AChE), butyrylcholinesterase (BChE), α-amylase, α-glucosidase, and tyrosinase inhibitory properties. Phenolics, alkaloids, glucosinolates and other sulfur-containing compounds were distinctively profiled in the different species. Maceration in methanol allowed recovering the highest cumulative phenolic content in A. scabrifolium (42.31 mg/g), followed by A. goekyigiti (33.15 mg/g) and A. atroviolaceum (28.35 mg/g). The aerial parts of all Allium species showed high in vitro antioxidant activity whereas methanolic extract of A. cappadocicum bulb showed the highest inhibition against AChE (2.44 mg galantamine equivalent/g) and the water extracts of A. isauricum aerial part were the best BChE inhibitors (4.31 mg galantamine equivalent/g). Bulbs were the richer source of oligosaccharides, and in vitro digestion determined an increase of oligosaccharides bioaccessibility. A promising nutraceutical potential could be highlighted in our understudied Allium species. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Reference of 33171-05-0).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Reference of 33171-05-0

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

A High-Performance Thin-Layer Chromatographic Method for the Simultaneous Determination of Curcumin I, Curcumin II and Curcumin III in Curcuma longa and Herbal Formulation was written by Abdel-Kader, Maged S.;Salkini, Ayman A.;Alam, Prawez;Alshahrani, Khaled A.;Foudah, Ahmed I.;Alqarni, Mohammed H.. And the article was included in Separations in 2022.Electric Literature of C19H16O4 The following contents are mentioned in the article:

Curcuma longa (turmeric) has traditionally been used in Ayurvedic, Unani and herbal drugs to cure numerous ailments. Due to the high demand, the quant. standardization of herbal products is challenging to maintain their quality. We aim to develop a rapid, sensitive and validated high-performance thin-layer chromatog. (HPTLC) method for the simultaneous determination and quantification of curcumin I, curcumin II and curcumin III in C. longa and herbal formulation. The three standards were separated using centrifugal preparative thin-layer chromatog. (CPTLC) silica gel and identified by different spectroscopic methods. The developed HPTLC method was validated by following ICH guidelines (linearity; limit of detection, LOD; limit of quantitation; accuracy; precision; and robustness). The calibration curves of both the compounds were linear (50-500 ng/spot), with a correlation coefficient (r2) of >999. The developed HPTLC method was effectively applied to the concurrent detection and quantification of curcumins I-III in fresh, dry rhizomes and the herbal formulation of C. longa extracts was obtained by hot and cold extraction methods. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Electric Literature of C19H16O4).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Electric Literature of C19H16O4

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synergistic effect of active metal-acid sites on hydrodeoxygenation of lignin-derived phenolic compounds under mild conditions using Ru/C-HPW catalyst was written by Yang, Zhi;Luo, Bowen;Shu, Riyang;Zhong, Zhuojie;Tian, Zhipeng;Wang, Chao;Chen, Ying. And the article was included in Fuel in 2022.Name: 4-Benzyloxyphenol The following contents are mentioned in the article:

Hydrodeoxygenation (HDO) is an indispensable reaction in the field of fuel and chem. production, and the synergistic effect of metal-acid sites in the catalyst makes great influence to it. Herein, a bifunctional catalyst of Ru/C combined with phosphotungstic acid (HPW) was employed for the hydrodeoxygenation (HDO) of lignin-derived compounds to make full use of the synergistic effect of active metal-acid sites. HPW possessed a temperature-controlled phase-transfer behavior, which made it dispersed well on the surface of Ru/C catalyst and resulted in a close integration of acid site with metal site. Ru/C-HPW catalyst also owned the advantage of high reaction rate and good recyclability, which exhibited no obvious catalytic activity loss after 5 runs. Lignin-derived phenolic compounds including monomers and dimers enabled to obtain an efficient transformation to cycloalkanes at the temperature of 200°C. Moreover, a high HDO reaction efficiency of raw lignin-oil was also observed in this study, with the increasing hydrocarbon content from 5.5% to 78.9%. This novel catalytic system can achieve a high HDO efficiency under mild conditions. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Name: 4-Benzyloxyphenol).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Name: 4-Benzyloxyphenol

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Comparison of Phenolic Profile of Balsamic Vinegars Determined Using Liquid and Gas Chromatography Coupled with Mass Spectrometry was written by Kaspar, Michal;Bajer, Tomas;Bajerova, Petra;Cesla, Petr. And the article was included in Molecules in 2022.Quality Control of 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

Balsamic vinegar is one of the best known and most popular types of vinegar, and it is a rich source of polyphenolic compounds The quality of balsamic vinegar as well as the content of phenolic substances vary depending on the production method. In the present work, we have developed a method for comprehensive characterization of the content of phenolic compounds in balsamic vinegars based on the combination of gas chromatog. (GC) and high-performance liquid chromatog. (HPLC) coupled with mass spectrometric detection in single mode (MS) and tandem mode (MS/MS). In total, 14 samples of different types of balsamic vinegar were analyzed without difficulty in sample preparation The separation conditions and detection parameters of HPLC-MS/MS were optimized and used for the determination of 29 phenolic compounds and 6 phenolic acids. The profile of phenolic compounds was completed by semi-quant. anal. of volatile organic compounds using GC-MS after optimized headspace solid-phase microextraction Gallic acid, protocatechuic acid, caffeic acid, and p-coumaric acid have been identified as the major phenolic compounds in balsamic vinegars. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Quality Control of 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Quality Control of 4-Hydroxy-3-methoxyphenethanol

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Central cholinergic agents. I. Potent acetylcholinesterase inhibitors, 2-[ω-[N-alkyl-N-(ω-phenylalkyl)amino]alkyl]-1H-isoindole-1,3(2H)-diones, based on a new hypothesis of the enzyme’s active site was written by Ishihara, Yuji;Kato, Koki;Goto, Giichi. And the article was included in Chemical & Pharmaceutical Bulletin in 1991.Name: N-(3-Methoxybenzyl)ethanamine The following contents are mentioned in the article:

It has been suggested that the active site of acetylcholinesterase contains a hydrophobic binding site (HBS-1), which is closely adjacent to both the anionic and the esteratic sites. In this paper, we assumed that there exists another hydrophobic binding site (HBS-2), some distance removed from the anionic site. On this assumption, a new working hypothesis was proposed for the design of acetylcholinesterase inhibitors. A series of 2-[ω-[N-alkyl-N-(ω-phenylalkyl)amino]alkyl]-1H-isoindole-1,3(2H)-diones (I, X = e.g., O₂N, OH, Me, Cl, amino group, or COPh, Y = e.g., H, halo OMe, R = H or alkyl, n = 3-9, m = 1-4) was designed based on this hypothesis and tested for its inhibitory activities on acetylcholinesterase. Some in this series were revealed to be more potent than physostigmine. Optimum activity was found to be associated with a five carbon chain length separating the benzylamino group from the 1H-isoindole-1,3(2H)-dione (phthalimide) moiety. Quant. study of substitution effect on the phthalimide moiety revealed that hydrophilic and electron-withdrawing groups enhance the activity. This study involved multiple reactions and reactants, such as N-(3-Methoxybenzyl)ethanamine (cas: 140715-61-3Name: N-(3-Methoxybenzyl)ethanamine).

N-(3-Methoxybenzyl)ethanamine (cas: 140715-61-3) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Name: N-(3-Methoxybenzyl)ethanamine

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Monobenzone, a novel and potent KDM1A inhibitor, suppresses migration of gastric cancer cells was written by Ma, Peizhi;Jia, Gang;Song, Zhiyu. And the article was included in Frontiers in Pharmacology in 2021.Computed Properties of C13H12O2 The following contents are mentioned in the article:

Lysine-specific demethylase1 (KDM1A) is generally highly expressed in various cancer tissues, and promotes the initiation and development of cancers via diverse cellular signaling pathways. Therefore, KDM1A is a promising drug target in many cancers, and it is crucial to find effective KDM1A inhibitors, while none of them has entered into market. With the help of compound library, monobenzone, a local depigmentor using as a treating over-pigmentation in clinic, was characterized as an effective KDM1A inhibitor (IC₅₀ = 0.4507 μM), which may competitively inhibit KDM1A reversibly. Further cellular study confirmed that monobenzone could inhibit the proliferation of gastric cancer cell lines MGC-803 and BGC-823 with IC₅₀ as 7.82 ± 0.55 μM and 6.99 ± 0.51 μM, resp., and erase the substrate of KDM1A, H3K4me1/2 and H3K9 me2, and inhibit the migration of gastric cancer cell by reversing epithelial-mesenchymal transition (EMT). As the structure of monobenzone is very simple and small, this study provides a novel backbone for the further optimization of KDM1A inhibitor and gives monobenzone potential new application. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Computed Properties of C13H12O2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Computed Properties of C13H12O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Monobenzone, a novel and potent KDM1A inhibitor, suppresses migration of gastric cancer cells was written by Ma, Peizhi;Jia, Gang;Song, Zhiyu. And the article was included in Frontiers in Pharmacology in 2021.HPLC of Formula: 103-16-2 The following contents are mentioned in the article:

Lysine-specific demethylase1 (KDM1A) is generally highly expressed in various cancer tissues, and promotes the initiation and development of cancers via diverse cellular signaling pathways. Therefore, KDM1A is a promising drug target in many cancers, and it is crucial to find effective KDM1A inhibitors, while none of them has entered into market. With the help of compound library, monobenzone, a local depigmentor using as a treating over-pigmentation in clinic, was characterized as an effective KDM1A inhibitor (IC₅₀ = 0.4507 μM), which may competitively inhibit KDM1A reversibly. Further cellular study confirmed that monobenzone could inhibit the proliferation of gastric cancer cell lines MGC-803 and BGC-823 with IC₅₀ as 7.82 ± 0.55 μM and 6.99 ± 0.51 μM, resp., and erase the substrate of KDM1A, H3K4me1/2 and H3K9 me2, and inhibit the migration of gastric cancer cell by reversing epithelial-mesenchymal transition (EMT). As the structure of monobenzone is very simple and small, this study provides a novel backbone for the further optimization of KDM1A inhibitor and gives monobenzone potential new application. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2HPLC of Formula: 103-16-2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. HPLC of Formula: 103-16-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Shape similarities of ultra-low interfacial tension curves in ternary microemulsion systems of the water-alkane-C_iE_j type was written by Sottmann, T.;Strey, R.. And the article was included in Berichte der Bunsen-Gesellschaft in 1996.Application of 112-59-4 The following contents are mentioned in the article:

The interfacial tensions between water- and oil-rich phases in microemulsion systems were measured for a series of ternary water-alkane-C_iE_j systems. Interfacial tensions vary over orders of magnitude with temperature displaying a pronounced min. for each surfactant. The center of the 3-phase temperature interval, T_u-T_l, i.e. the phase inversion temperature (PIT), corresponds to the temperature T_m of the min. in interfacial tension. Increasing the surfactant chain length the min. value decreases by 3 orders of magnitude for a change of i from 6 to 12. Interestingly, all interfacial tension curves have a similar shape. Centering the curves around T_m and reducing the temperature scale by T_u-T_l permits determining the factors by which the individual interfacial tension curves differ. The factors are be proportional, resp., to square of the maximum length scale ζ or the inverse surfactant volume fraction ϕ^–_c,i in the interface. Accordingly, plotting σ_ab/ϕ_c,i² vs. 2(T-T_m)/(T_u-T₁) an almost perfect superposition of all interfacial tension curves is observed This study involved multiple reactions and reactants, such as 2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4Application of 112-59-4).

2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Application of 112-59-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem