Category: ethers-buliding-blocks

Value-addition of wheat straw through acid treatment and pyrolysis of acid treated residues was written by Verma, Rameshwari;Verma, Santosh K.;Verma, Shekhar;Wang, Jia;Liu, Jianbo;Jing, Bei;Rakesh, K. P.. And the article was included in Journal of Cleaner Production in 2021.Related Products of 2380-78-1 The following contents are mentioned in the article:

Agricultural straw utilization has become a big concern in many countries with abundance of the production While different comprehensive utilization methods have been used for the bio-oil production, complete uses of the waste biomass into useful products need to be examined to reduce the environmental burdens of agricultural straw disposal. By deploying value addition of straw biomass, this article evaluates the two process for the complete utilization of straw including acid treatment into carbohydrates rich compounds and acid treated residue pyrolysis to phenolic and ketonic rich compounds Effects of intrinsic alk. and alk. earth metals on wheat straw pyrolysis behavior and product distribution investigated. Acid pickling was executed employing HCl, HF and HCl + HF solution Pyrolysis products of acid treated wheat straw were investigated. Fixed bed reaction results showed that acid pickling is beneficial to the production of liquid, the yield of liquid increased from 37.48 wt% raw wheat straw to 42.24 wt% wheat straw-HCl, 48.03 wt% wheat straw -HF, and 47.20 wt% wheat straw-HCl + HF. The relative content of compounds identified by GC/MS in bio-oil changed significantly after acid pickling. Sugar increased from 1.43% wheat straw to 25.27% wheat straw-HCl, 19.00% wheat straw-HF and 19.78% wheat straw-HCl + HF. Particularly, D-Allose, which has been increased from 0.19% wheat straw to 22.18% wheat straw-HCl, 7.22% wheat straw-HF, and 7.89% wheat straw-HCl + HF. These results provide evidence that the straw biomass has good potential to increase bioenergy production This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Related Products of 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Related Products of 2380-78-1

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Discovery of novel N-benzylbenzamide derivatives as tubulin polymerization inhibitors with potent antitumor activities was written by Zhu, Huajian;Li, Wenlong;Shuai, Wen;Liu, Yang;Yang, Limei;Tan, Yuchen;Zheng, Tiandong;Yao, Hong;Xu, Jinyi;Zhu, Zheying;Yang, Dong-Hua;Chen, Zhe-Sheng;Xu, Shengtao. And the article was included in European Journal of Medicinal Chemistry in 2021.COA of Formula: C3H9NO The following contents are mentioned in the article:

A series of novel N-benzylbenzamide derivatives I (R = dimethylaminyl, piperidin-1-yl, morpholin-4-yl, etc.; R¹ = H, Cl, NO₂, (pyridin-4-ylmethyl)aminyl, etc.; R² = H, NO₂; R³ = (3-hydroxy-4-methoxyphenyl)methyl, (3-fluoro-4-methoxyphenyl)methyl, pyridin-4-ylmethyl, etc.; R⁴ = H, Me), II (X = Y = N, CH) and III were designed and synthesized as tubulin polymerization inhibitors. Among fifty-one target compounds, I, II and III compound I [R = morpholin-4-yl; R¹ = F; R² = H; R³ = (3-hydroxy-4-methoxyphenyl)methyl; R⁴ = H] (IV) exhibited significant antiproliferative activities with IC₅₀ values ranging from 12 to 27 nM against several cancer cell lines, and possessed good plasma stability and satisfactory physicochem. properties. Mechanism studies demonstrated that IV bound to the colchicine binding site and displayed potent anti-vascular activity. Notably, the corresponding disodium phosphate III exhibited an excellent safety profile with the LD₅₀ value of 599.7 mg/kg (i.v. injection), meanwhile, it significantly inhibited tumor growth and decreased microvessel d. in liver cancer cell H22 allograft mouse model without obvious toxicity. Collectively, IV and III are novel promising anti-tubulin agents with more druggable properties and deserve to be further investigated for cancer therapy. This study involved multiple reactions and reactants, such as 2-Methoxyethylamine (cas: 109-85-3COA of Formula: C3H9NO).

2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.COA of Formula: C3H9NO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

A very long-acting parp inhibitor suppresses cancer cell growth in DNA repair-deficient tumor models was written by Fontaine, Shaun D.;Ashley, Gary W.;Houghton, Peter J.;Kurmasheva, Raushan T.;Diolaiti, Morgan;Ashworth, Alan;Peer, Cody J.;Nguyen, Ryan;Figg, William D. Sr.;Beckford-Vera, Denis R.;Santi, Daniel V.. And the article was included in Cancer Research in 2021.Category: ethers-buliding-blocks The following contents are mentioned in the article:

PARP inhibitors are approved for treatment of cancers with BRCA1 or BRCA2 defects. In this study, we prepared and characterized a very long-acting PARP inhibitor. Synthesis of a macromol. prodrug of talazoparib (TLZ) was achieved by covalent conjugation to a PEG_40kDa carrier via a β-eliminative releasable linker. A single injection of the PEG~TLZ conjugate was as effective as ~30 daily oral doses of TLZ in growth suppression of homologous recombination-defective tumors in mouse xenografts. These included the KT-10 Wilms′′ tumor with a PALB2 mutation, the BRCA1-deficient MX-1 triple-neg. breast cancer, and the BRCA2-deficient DLD-1 colon cancer; the prodrug did not inhibit an isogenic DLD-1 tumor with wild-type BRCA2. Although the half-life of PEG~TLZ and released TLZ in the mouse was only ~1 day, the exposure of released TLZ from a single safe, ED of the prodrug exceeded that of oral TLZ given daily over one month. μPET/CT imaging showed high uptake and prolonged retention of an 89Zr-labeled surrogate of PEG~TLZ in the MX-1 BRCA1-deficient tumor. These data suggest that the long-lasting antitumor effect of the prodrug is due to a combination of its long t_1/2, the high exposure of TLZ released from the prodrug, increased tumor sensitivity upon continued exposure, and tumor accumulation. Using pharmacokinetic parameters of TLZ in humans, we designed a long-acting PEG~TLZ for humans that may be superior in efficacy to daily oral TLZ and would be useful for treatment of PARP inhibitor-sensitive cancers in which oral medications are not tolerated. This study involved multiple reactions and reactants, such as 2-Methoxyethylamine (cas: 109-85-3Category: ethers-buliding-blocks).

2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Towards supramolecular nanostructured materials: control of the self-assembly of ionic bent-core amphiphiles was written by Castillo-Valles, Martin;Cano, Miguel;Bermejo-Sanz, Ana;Gimeno, Nelida;Ros, M. Blanca. And the article was included in Journal of Materials Chemistry in 2020.COA of Formula: C13H12O2 The following contents are mentioned in the article:

Control of the bottom-up self-assembly of ionic bent-core dendrimers has been systematically studied by mol. design. This process gave rise to architectures with diverse packing, shapes and dimensions to construct structured materials at the nanoscale. The compact organization of the mols. achieved in bent-core mesophases was transferred or induced to self-assemblies in the presence of water – even in the case of non-mesogenic dendrimers. The subtle balance of mol.-mol. and mol.-solvent interactions regulated the morphol. of the aggregates and these ranged from rods, non-twisted or twisted fibers, helical ribbons and nanotubes. The structure obtained was dependent on the choice of dendritic nucleus, the bent-core structure (from 5 to 3 aromatic ring systems), the lateral moiety and the length of the outer flexible tails. The rigid nature of the chem. structure controlled the type of mol. packing in the layers and allowed mol. conformational chirality to be transmitted to the supramol. aggregates, despite achiral mols. being used. The short/long terminal chain lengths determined the type of curvature of the ribbons. Some of these self-assemblies are proposed as alternatives to the attractive and widely applied helical nanofilaments formed by bent-core mesogens, but, thanks to their amphiphilic nature, the novel compounds can be processed from solution Moreover, the self-assembly process was studied in an effort to elucidate the aggregation mechanism of these bent-shaped amphiphiles and to define exptl. protocols to provide high quality and homogeneous aggregates. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2COA of Formula: C13H12O2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.COA of Formula: C13H12O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Towards supramolecular nanostructured materials: control of the self-assembly of ionic bent-core amphiphiles was written by Castillo-Valles, Martin;Cano, Miguel;Bermejo-Sanz, Ana;Gimeno, Nelida;Ros, M. Blanca. And the article was included in Journal of Materials Chemistry in 2020.COA of Formula: C13H12O2 The following contents are mentioned in the article:

Control of the bottom-up self-assembly of ionic bent-core dendrimers has been systematically studied by mol. design. This process gave rise to architectures with diverse packing, shapes and dimensions to construct structured materials at the nanoscale. The compact organization of the mols. achieved in bent-core mesophases was transferred or induced to self-assemblies in the presence of water – even in the case of non-mesogenic dendrimers. The subtle balance of mol.-mol. and mol.-solvent interactions regulated the morphol. of the aggregates and these ranged from rods, non-twisted or twisted fibers, helical ribbons and nanotubes. The structure obtained was dependent on the choice of dendritic nucleus, the bent-core structure (from 5 to 3 aromatic ring systems), the lateral moiety and the length of the outer flexible tails. The rigid nature of the chem. structure controlled the type of mol. packing in the layers and allowed mol. conformational chirality to be transmitted to the supramol. aggregates, despite achiral mols. being used. The short/long terminal chain lengths determined the type of curvature of the ribbons. Some of these self-assemblies are proposed as alternatives to the attractive and widely applied helical nanofilaments formed by bent-core mesogens, but, thanks to their amphiphilic nature, the novel compounds can be processed from solution Moreover, the self-assembly process was studied in an effort to elucidate the aggregation mechanism of these bent-shaped amphiphiles and to define exptl. protocols to provide high quality and homogeneous aggregates. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2COA of Formula: C13H12O2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.COA of Formula: C13H12O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Potential therapeutic effect of turmeric contents against SARS-CoV-2 compared with experimental COVID-19 therapies: in silico study was written by Emirik, Mustafa. And the article was included in Journal of Biomolecular Structure and Dynamics in 2022.COA of Formula: C19H16O4 The following contents are mentioned in the article:

Inspired by the ‘There is no scientific evidence that turmeric prevents COVID-19’ statement made by WHO, the protective or therapeutic potential of the compounds in turmeric contents was investigated against COVID-19 with in silico methodol. The drugs used for exptl. COVID-19 therapies were included in this study using the same method for comparison with turmeric components. The 30 turmeric compounds and nine drugs were performed in the docking procedure for vital proteins of COVID-19. With evaluations based on docking scores, the Prime MMGBSA binding free energy and protein-ligand interactions were identified in detail. The 100 ns MD simulations were also performed to assess the stability of the ligands at the binding site of the target proteins. The Root Mean Square Deviation (RMSD) is used to obtain the average displacement for a particular frame concerning a reference frame. The results of this study are suggesting that turmeric spice have a potential to inhibit the SARS-CoV-2 vital proteins and can be use a therapeutic or protective agent against SARS-CoV-2 via inhibiting key protein of the SARS-CoV-2 virus. The compound 4, 23 and 6 are the most prominent inhibitor for the main protease, the spike glycoprotein and RNA polymerase of virus, resp. The MD simulation validated the stability of ligand-protein interactions. The compactness of the complexes was shown using a radius of gyration. ADME properties of featured compounds are in range of 95% drug mols. It is hoped that the outputs of this study will contribute to the struggle of humanity with COVID-19. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0COA of Formula: C19H16O4).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.COA of Formula: C19H16O4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Hydrotropic Extraction of Carnosic Acid from Rosemary with Short-Chain Alkyl Polyethylene Glycol Ethers was written by Mazaud, Agathe;Lebeuf, Raphael;Laguerre, Mickael;Nardello-Rataj, Veronique. And the article was included in ACS Sustainable Chemistry & Engineering in 2020.Application of 112-59-4 The following contents are mentioned in the article:

Carnosic acid (CA) is a hydrophobic secondary metabolite and the main antioxidant of rosemary. Extractions of CA from whole leaves of rosemary have been performed with aqueous solutions of 12 short-chain alkyl polyethylene glycol ethers, abbreviated as C_iE_j with i = 4-8 and j = 1-4. Such compounds act as hydrotropes which are known to enhance the solubilization of hydrophobic mols. in water while avoiding the formation of liquid crystals like surfactants. The extractions are compared with those carried out with alcs., sodium xylene sulfonate (SXS) which is an archetypical ionic hydrotrope, and longer C_iE_j (i = 10 or 12 and j = 4) which behave as true surfactants. C₅E₂ and C₄E₁ are the best candidates and provide 1.21 g/L CA in 21 h and 1.02 g/L in 8 h, resp. They are more efficient than SXS and alc. aqueous solutions Correlations between the chem. structure and activity have highlighted three requirements for better performances: (i) a small mol. volume V_m (<250 ų), (ii) a log P above 1, and (iii) a linear alkyl chain rather than a branched one. Finally, kinetic study and optical microscopy observations of the leaves after extraction give insight into the mode of action of the C₄E_j compared to ethanol. Here, we investigate the use of aqueous solutions of nonionic hydrotropes to extract phytochems. in a process that mitigates emissions of volatile organic compounds compared to extraction routes using conventional solvents. This study involved multiple reactions and reactants, such as 2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4Application of 112-59-4).

2-(2-(Hexyloxy)ethoxy)ethanol (cas: 112-59-4) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Application of 112-59-4

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Novel Soloxolone Amides as Potent Anti-Glioblastoma Candidates: Design, Synthesis, In Silico Analysis and Biological Activities In Vitro and In Vivo was written by Markov, Andrey V.;Ilyina, Anna A.;Salomatina, Oksana V.;Sen’kova, Aleksandra V.;Okhina, Alina A.;Rogachev, Artem D.;Salakhutdinov, Nariman F.;Zenkova, Marina A.. And the article was included in Pharmaceuticals in 2022.COA of Formula: C3H9NO The following contents are mentioned in the article:

The modification of natural or semisynthetic triterpenoids with amines can be explored as a promising strategy for improving their pharmacol. properties. Here, we report the design and synthesis of 11 novel amide derivatives of soloxolone Me (SM), a cyano enone-bearing derivative of 18βH-glycyrrhetinic acid. Anal. of their bioactivities in vitro and in silico revealed their high toxicity against a panel of tumor cells (average IC50(24h) = 3.7 μM) and showed that the formation of amide moieties at the C-30 position of soloxolone did not enhance the cytotoxicity of derivatives toward tumor cells compared to SM, though it can impart an ability to pass across the blood-brain barrier. Further HPLC-MS/MS and mechanistic studies verified significant brain accumulation of hit compound 12 (soloxolone tryptamide) in a murine model and showed its high anti-glioblastoma potential. It was found that 12 induced ROS-dependent and autophagy-independent death of U87 and U118 glioblastoma cells via mitochondrial apoptosis and effectively blocked their clonogenicity, motility and capacity to form vessel-like structures. Further in vivo study demonstrated that i.p. injection of 12 at a dosage of 20 mg/kg effectively inhibited the growth of U87 glioblastoma in a mouse xenograft model, reducing the proliferative potential of the tumor and leading to a depletion of collagen content and normalization of blood vessels in tumor tissue. The obtained results clearly demonstrate that 12 can be considered as a promising leading compound for drug development in glioblastoma treatment. This study involved multiple reactions and reactants, such as 2-Methoxyethylamine (cas: 109-85-3COA of Formula: C3H9NO).

2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.COA of Formula: C3H9NO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Design and synthesis of novel benzothiophene analogs as selective estrogen receptor covalent antagonists against breast cancer was written by Bai, Chengfeng;Ren, Shengnan;Wu, Shuangjie;Zhu, Meiqi;Luo, Guoshun;Xiang, Hua. And the article was included in European Journal of Medicinal Chemistry in 2021.COA of Formula: C13H12O2 The following contents are mentioned in the article:

Endocrine therapy (ET) has benefited patients with estrogen receptor alpha (ERα) pos. breast cancer for decades. Selective estrogen receptor modulator (SERM) such as Tamoxifen represents the clin. standard of care (SoC). Despite the therapeutic importance of current SoC agents, 30-50% of prolonged treatment patients inevitably generated resistant tumor cells, usually eventually suffered tumor relapse and developed into metastatic breast cancer (MBC), which was the leading cause of female cancer-related mortality. Among these, most resistant tumors remained dependent on ERα signaling, which reignited the need for the next generation of ERα related agents. Authors hypothesized that selective estrogen receptor covalent antagonists targeting ERα would provide a therapeutic alternative. In the current work, series of novel benzothiophene hybrids I (R₁ = H, Me; R₂ = Me; R₁R₂ = (CH₂)₃, (CH₂)₅, etc.) II, III (R₃ = R₄ = H, Me) and IV bearing electrophile moieties were synthesized and biol. evaluated. The representative analog I (R₁R₂ = (CH₂)₃) exhibited potent anti-proliferative effect in MCF-7 cell lines in vitro, and further mechanism studies confirmed the necessity of covalent bonding. More importantly, I could attenuate the expression of TFF-1, GREB-1 and down-regulate the levels of cellular ERα protein. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2COA of Formula: C13H12O2).

4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.COA of Formula: C13H12O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Antioxidant Additives Produced from Argan Shell Lignin Depolymerization was written by Afailal, Zainab;Gil-Lalaguna, Noemi;Torrijos, Maria Teresa;Gonzalo, Alberto;Arauzo, Jesus;Sanchez, Jose Luis. And the article was included in Energy & Fuels in 2021.Formula: C9H12O3 The following contents are mentioned in the article:

The present work summarizes the results of an exptl. study focused on producing antioxidant additives for biofuels from argan shell lignin. The generation of this waste has noticeably increased in specific regions of Morocco as a result of the upward trend in the production of argan oil. Lignin extracted from argan shells via a semi-chem. pulping process was depolymerized under hydrothermal conditions in a stirred autoclave reactor at a temperature range of 250-350°C. Lignin conversion to phenolic compounds was conducted in subcritical water together with different reaction medium (H₂, CO₂, and HCOOH). The organic fraction in the aqueous liquid product was extracted and blended with biodiesel at a dosage of 1 wt % to evaluate its antioxidant potential. According to the obtained results, the biodiesel oxidation stability time was drastically improved up to 400%. The depolymerization temperature was observed as a critical factor in the antioxidant potential of the additives, showing a maximum value at 300°C, regardless of the reaction medium. An extensive characterization of the produced additives was performed. The phenolic monomers present in the produced additives were identified using gas chromatog.-mass spectrometry, finding a notable presence of catechol, especially in the additives obtained at 300°C, which led to the best results of biodiesel oxidation stability. Gel permeation chromatog. analyses of the additives also showed a well dissolution of relatively big mols. (up to 7000 Da) in biodiesel. More efforts are required to verify the actual antioxidant potential of these types of mols. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Formula: C9H12O3).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Formula: C9H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem