Category: ethers-buliding-blocks

Solvent effects on Li ion transference number and dynamic ion correlations in glyme- and sulfolane-based molten Li salt solvates was written by Shigenobu, Keisuke;Dokko, Kaoru;Watanabe, Masayoshi;Ueno, Kazuhide. And the article was included in Physical Chemistry Chemical Physics in 2020.Name: 2,5,8,11-Tetraoxadodecane This article mentions the following:

The Li⁺ transference number of electrolytes is one of the key factors contributing to the enhancement in the charge-discharge performance of Li secondary batteries. However, a design principle to achieve a high Li⁺ transference number has not been established for liquid electrolytes. To understand the factors governing the Li⁺ transference number t_Li, we investigated the influence of the ion-solvent interactions, Li ion coordination, and correlations of ion motions on the Li⁺ transference number in glyme (Gn, n = 1-4)- and sulfolane (SL)-based molten Li salt solvate electrolytes with lithium bis(trifluoromethansulfonyl)amide (LiTFSA). For the 1 : 1 tetraglyme-LiTFSA molten complex, [Li(G4)][TFSA], the Li⁺ transference number estimated using the potentiostatic polarisation method (t^PP_Li = 0.028) was considerably lower than that estimated using the self-diffusion coefficient data with pulsed filed gradient (PFG)-NMR (t^NMR_Li = 0.52). The dynamic ion correlations (i.e., cation-cation, anion-anion, and cation-anion cross-correlations) were determined from the exptl. data on the basis of Roling and Bedrov′s concentrated solution theory, and the results suggest that the strongly neg. cross-correlations of the ion motions (especially for cation-cation motions) are responsible for the extremely low t^PP_Li of [Li(G4)][TFSA]. In contrast, t^PP_Li is larger than t^NMR_Li in the SL-based electrolytes. The high t^PP_Li of the SL-based electrolytes was ascribed to the substantially weaker anti-correlations of cation-cation and cation-anion motions. Whereas the translational motions of the long-lived [Li(glyme)]⁺ and [TFSA]^– dominate the ionic conduction for [Li(G4)][TFSA], Li ion hopping/exchange conduction was reported to be prevalent in the SL-based electrolytes. The unique Li ion conduction mechanism is considered to contribute to the less correlated cation-cation and cation-anion motions in SL-based electrolytes. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2Name: 2,5,8,11-Tetraoxadodecane).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Name: 2,5,8,11-Tetraoxadodecane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Cobalt/Salox-Catalyzed Enantioselective C-H Functionalization of Arylphosphinamides was written by Yao, Qi-Jun;Chen, Jia-Hao;Song, Hong;Huang, Fan-Rui;Shi, Bing-Feng. And the article was included in Angewandte Chemie, International Edition in 2022.Application In Synthesis of 1,4-Dimethoxy-2-butyne This article mentions the following:

Previous methods on Co(III)-catalyzed asym. C-H activation rely on the use of tailor-made cyclopentadienyl-ligated Co(III) complexes, which require lengthy steps for the preparation Herein, the authors report an unprecedented enantioselective C-H functionalization enabled by a simple Co/salicyloxazoline (Salox) catalysis. The chiral Salox ligands can be easily prepared in one step from salicylonitrile and chiral amino alcs. A broad range of P-stereogenic compounds were synthesized in high yields with excellent enantioselectivities (45 examples, up to 99% yield and >99% ee). The isolation and characterization of several intermediates provided insights into the generation of active catalytic Co species, the action of Salox, and the mode of stereocontrol. In the experiment, the researchers used many compounds, for example, 1,4-Dimethoxy-2-butyne (cas: 16356-02-8Application In Synthesis of 1,4-Dimethoxy-2-butyne).

1,4-Dimethoxy-2-butyne (cas: 16356-02-8) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Application In Synthesis of 1,4-Dimethoxy-2-butyne

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

A concise synthetic approach towards hydroxytetraphenylenes was written by Cui, Jian-Fang;Huang, Hui;Wong, Henry N. C.. And the article was included in Synlett in 2011.Related Products of 56619-93-3 This article mentions the following:

This communication is concerned with our efforts in improving the syntheses of five hydroxytetraphenylens, which we obtained before. A short consecutive direct ortho-metalation and oxidative coupling sequence from N-pivaloyl-protected substituted aniline provided the corresponding 2,2′-diiodobiphenyls. Subsequently, copper(II)-mediated oxidative coupling of 2,2′-diiodobiphenyls successfully led to the formation of the corresponding hydroxytetraphenylenes. This is the first time that hydroxytetraphenylenes were all realized via oxidative cross-coupling reactions from the corresponding 2,2′-diiodobiphenyls. In the experiment, the researchers used many compounds, for example, N-(3-Methoxyphenyl)pivalamide (cas: 56619-93-3Related Products of 56619-93-3).

N-(3-Methoxyphenyl)pivalamide (cas: 56619-93-3) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Related Products of 56619-93-3

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Supported liquid membrane transport of alkali metal cations by monoazacryptand with a partially fluorinated sidearm and the corresponding monoazacrown ethers was written by Nakatsuji, Yohji;Fujimoto, Shingo;Nakamura, Misako;Muraoka, Masahiro. And the article was included in Journal of Oleo Science in 2010.Category: ethers-buliding-blocks This article mentions the following:

Monoazacryptand [20.18.18] (1), monoaza-15-crown-5 (2a), and monoaza-18-crown-6 (2b) with a partially fluorinated sidearm were newly prepared and their transport abilities were estimated in a supported liquid membrane containing a mixture of 2-(perfluorohexyl) Et alc. and 2- (perfluorooctyl) Et alc. In competitive passive transport of K⁺, Na⁺, and Li⁺ under neutral conditions, the K⁺ selectivity increased in the order: ionophore 2a<ionophore 2b<ionophore 1; whereas, the transport velocity increased in the order: ionophore 2a<ionophore 1<ionophore 2b. On the other hand, only ionophore 1 successfully transported K⁺ in the transport from the neutral source phase to the acidic receiving phase. This result was reasonably explained by considering the excellent K⁺ complexing ability of monoazacryptand (1) in comparison with that of monoazacrown ethers (2a and 2b). In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3Category: ethers-buliding-blocks).

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Highly (E)-Selective Tri-Substituted Alkene Synthesis by Low-Valent Titanium-Mediated Homolytic Cleavage of Alcohol C-O Bond was written by Suga, Takuya;Takada, Ryusei;Shimazu, Shoma;Sakata, Mizuki;Ukaji, Yutaka. And the article was included in Journal of Organic Chemistry in 2022.Related Products of 105-13-5 This article mentions the following:

Ti-mediated homolytic C-O bond cleavage was useful for cascade radical-ionic reactions. Benzyl alcs. treated with TiCl₄(col) (col = 2,4,6-collidine) and Mn powder generated the corresponding benzyl radicals; in addition, their reaction with 2-carboxy-allyl acetates and the subsequent elimination of the acetoxy group yielded α,β-unsaturated carbonyl compounds I [R = Ph, 1-phenylethyl, undecyl, etc.; Ar = Ph, 4-MeOC₆H₄, 1-naphthyl, etc.] with exclusive (E)-stereoselectivity. The simplicity of the procedure and its wide substrate scope represented a solution to the drawbacks associated with the reactions. In the experiment, the researchers used many compounds, for example, (4-Methoxyphenyl)methanol (cas: 105-13-5Related Products of 105-13-5).

(4-Methoxyphenyl)methanol (cas: 105-13-5) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Related Products of 105-13-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Copper-Catalyzed Borylation Reactions of Alkynes and Arynes was written by Yoshida, Hiroto;Kawashima, Shota;Takemoto, Yuki;Okada, Kengo;Ohshita, Joji;Takaki, Ken. And the article was included in Angewandte Chemie, International Edition in 2012.Product Details of 16356-02-8 This article mentions the following:

Authors have demonstrated that an easily accessible copper-phosphine complex served as a potent catalyst for the direct formation of diverse cis-vic-diborylalkenes (or vic-diborylarenes) by diborylation of alkynes (or arynes). With this catalyst, propargyl ethers smoothly underwent tetra- and triborylation by formal C-O bond borylation accompanied by diborylation of the alkyne moieties. Moreover, the resulting diborylation product has been demonstrated to serve as an intermediate in the synthesis of the pharmacol. significant compounds F050 and F1070. In the experiment, the researchers used many compounds, for example, 1,4-Dimethoxy-2-butyne (cas: 16356-02-8Product Details of 16356-02-8).

1,4-Dimethoxy-2-butyne (cas: 16356-02-8) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Product Details of 16356-02-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Formal C-H Carboxylation of Unactivated Arenes was written by Gevorgyan, Ashot;Hopmann, Kathrin H.;Bayer, Annette. And the article was included in Chemistry – A European Journal in 2020.Recommanded Product: 365564-07-4 This article mentions the following:

A formal C-H carboxylation of unactivated arenes e.g., I using CO₂ in green solvents is described. The present strategy combines a sterically controlled Ir-catalyzed C-H borylation followed by a Cu-catalyzed carboxylation of the in situ generated organoboronates. The reaction is highly regioselective for the C-H carboxylation of unactivated arenes e.g., I (1,3-disubstituted and 1,2,3-trisubstituted benzenes, 1,2- or 1,4-sym. substituted benzenes, fluorinated benzenes and different heterocycles). The developed methodol. was applied to the late-stage C-H carboxylation of com. drugs and ligands. In the experiment, the researchers used many compounds, for example, 2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 365564-07-4Recommanded Product: 365564-07-4).

2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 365564-07-4) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Recommanded Product: 365564-07-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The examination of a variety of different ions added to the crown ether derivatives with high field NMR spectrometer was written by Askin, Muzaffer;Zengin, Bilgin;Korunur, Sibel;Kor, Harun;Koylu, M. Zafer. And the article was included in Russian Journal of Physical Chemistry B in 2017.Recommanded Product: 66943-05-3 This article mentions the following:

The current study involves the measurements of T₁ relaxation time of complexes three different crown ethers (4-aminobenzo-15-Crown-5, 1-Aza-18-Crown-6, 1-Aza-15-Crown-5) and two different ions sodium perchlorate (NaClO₄), lithium perchlorate (LiClO₄) by a 400 MHz NMR spectrometer. The association constants (K_a) of the complexes were determined on the basis of the evaluation of these measurements using the Benesi-Hildebrand method that we have modified. These association constants were consistent with those obtained from ¹H NMR titration technique. As a result, it can be speculated that binding constants could be measured using T₁ relaxation time when chem. shifts are very small or cannot be observed In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3Recommanded Product: 66943-05-3).

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Recommanded Product: 66943-05-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Synthesis of 1,2-Disubstituted Benzimidazoles via Acceptorless Dehydrogenative Coupling Using Ru(II)-Arene Catalysts Containing Ferrocene Thiosemicarbazone was written by Ravindran N E, Aswathi;Sindhuja, Dharmalingam;Bhuvanesh, Nattamai;Karvembu, Ramasamy. And the article was included in European Journal of Inorganic Chemistry in 2022.Recommanded Product: 105-13-5 This article mentions the following:

The catalytic activity of Ru(II)-arene complexes containing ferrocene thiosemicarbazone (Fc-TSC) ligands was investigated toward the selective synthesis of 1,2-disubstituted benzimidazoles I [R = n-Pr, Ph, 4-MeOC₆H₄, etc.; X = H, 6-Cl, 5-Me, 6-Me] via acceptorless dehydrogenative coupling of diamines with primary alcs. A series of Ru(II)-p-cymene complexes II [R¹ = H, Me, Ph, cyclohexyl] containing Fc-TSC ligands III were synthesized and characterized. From single crystal X-ray crystallog. studies, the mol. structures of III [R¹ = cyclohexyl] and II [R¹ = Ph] were confirmed. The influence of electronic effect of ligands on the catalytic activity of their complexes was studied. The activity of good performer i. e. II [R¹ = Ph] was compared with that of its benzene counterpart IV. The catalysis was extended to aromatic, aliphatic and heterocyclic substituted primary alcs., and phenylenediamines with electron-donating or -withdrawing substituents. Overall, synthesis of 1,2-disubstituted benzimidazoles I was accomplished with good to moderate yields, with hydrogen and water as only byproducts. In the experiment, the researchers used many compounds, for example, (4-Methoxyphenyl)methanol (cas: 105-13-5Recommanded Product: 105-13-5).

(4-Methoxyphenyl)methanol (cas: 105-13-5) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Recommanded Product: 105-13-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Aminophenols as efficient ligands for copper-catalyzed Ullmann-type synthesis of diaryl ethers was written by Qian, Cunwei;Qin, Liang;Zong, Qianshou;Wu, Lin;Fang, Dong. And the article was included in Bulletin of the Korean Chemical Society in 2013.Quality Control of 1-(4-(4-Methoxyphenoxy)phenyl)ethanone This article mentions the following:

An efficient copper-aminophenol (I) catalyzed synthesis of diaryl ethers R¹OR² (R¹ = 4-MeC₆H₄, 4-ClC₆H₄; R² = 4-MeOC₆H₄, Ph; etc.) via Ullmann coupling of phenols/naphthols and aryl bromides/iodides was reported. In the experiment, the researchers used many compounds, for example, 1-(4-(4-Methoxyphenoxy)phenyl)ethanone (cas: 54916-28-8Quality Control of 1-(4-(4-Methoxyphenoxy)phenyl)ethanone).

1-(4-(4-Methoxyphenoxy)phenyl)ethanone (cas: 54916-28-8) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Quality Control of 1-(4-(4-Methoxyphenoxy)phenyl)ethanone

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem