Tag: 100-200

On March 10, 1994, Achard, D.; Truchon, A.; Peyronel, J. F. published an article.Computed Properties of 81616-80-0 The title of the article was Perhydrothiopyranopyrroles derivatives: a novel series of potent and selective nonpeptide NK1 antagonists. And the article contained the following:

The synthesis of RP 73467 (I), a representative of 4,4-di-Ph perhydrothiopyrano[2,3-c]-pyrrole-1-oxides, a new series of potent and selective nonpeptide NK1 Substance P antagonists, is described. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Computed Properties of 81616-80-0

The Article related to perhydrothiopyranopyrrole derivative nk1 receptor antagonist preparation, Pharmacology: Structure-Activity and other aspects.Computed Properties of 81616-80-0

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On May 1, 2012, Liu, Chang; Jin, Jing; Chen, Liang; Zhou, Jie; Chen, Xiaoguang; Fu, Decai; Song, Hongrui; Xu, Bailing published an article.Reference of 1-Fluoro-2-methoxybenzene The title of the article was Synthesis and biological evaluation of novel human Pin1 inhibitors with benzophenone skeleton. And the article contained the following:

A series of novel benzophenone derivatives were prepared and their inhibitory activities were evaluated on hPin1. Of all the synthesized compounds, the most active compound displayed inhibitory activities with an IC50 value of 5.99 μmol/L. Preliminary structure-activity relationships were analyzed in details and the binding mode of the titled compounds was predicted using FlexX algorithm. The results of this research will shed light on further design and optimization of novel small mol. Pin1 inhibitors. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Reference of 1-Fluoro-2-methoxybenzene

The Article related to benzophenone derivative preparation structure pin1 inhibitor, Pharmacology: Structure-Activity and other aspects.Reference of 1-Fluoro-2-methoxybenzene

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On July 31, 2021, Koparan, Arzu; Gokalp, Mine published an article.Formula: C11H10O The title of the article was A Validated Method for Separation and Determination of Codeine Phosphate Hemihydrate Impurities in Bilayer Tablet Dosage Form of Naproxen Sodium and Codeine Phosphate by Using UHPLC. And the article contained the following:

Apranax Plus is a new bilayer tablet dosage form, which combines two active pharmaceutical ingredients: naproxen sodium and codeine phosphate. The purpose of this work was to develop an Ultra-High-Performance Liquid Chromatog. (UHPLC) method for the separation and determination of codeine phosphate hemihydrate impurities in a bilayer tablet dosage form. The separation and determination of codeine phosphate hemihydrate and its impurities, methylcodeine, morphine, codeine dimer, 10-hydroxycodeine, 14-hydroxycodeine, thebaine and codeinone were achieved by using reversed-phase liquid chromatog. with TUV (Tunable UV Detector) and PDA (Photodiode Array Detector) detection by UHPLC. The new proposed method utilized by the Waters Acquity UHPLC TUV and PDA systems using a UHPLC column Waters Acquity, BEH, C18, 2.1×100 mm, 1.7μm particle size with a mixture of component A and acetonitrile in a gradient mode at a flow rate of 0.3mL/min, at 25°C with a load of 5μL. The detection for all eluted compounds was carried out at 245nm. The codeine phosphate hemihydrate and peaks of its impurities were adequately obtained, thus proving the stability-indicating power of the method. The developed method was validated as per the ICH guidelines with respect to parameters such as precision, accuracy, linearity, Limit of Detection (LOD), Limit of Quantification (LOQ) and robustness. It was verified as being adequate for all the mentioned impurities of codeine phosphate hemihydrate. The described method was found to be useful for routine purity testing and was also found suitable for the anal. of the stability samples of the drug product. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Formula: C11H10O

The Article related to codeine phosphate hemihydrate naproxen sodium uhplc, Pharmaceutical Analysis: General and other aspects.Formula: C11H10O

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Jiang, Xiaojia; Zang, Mingsong; Li, Fei; Hou, Chunxi; Luo, Quan; Xu, Jiayun; Liu, Junqiu published an article in 2021, the title of the article was Highly sensitive detection of paraquat with pillar[5]arenes as aptamer in alpa-hemolysin nanopore.Product Details of 150-78-7 And the article contains the following content:

Recently, biol. nanopore-based techniques have attracted more and more attention in the field of single-mol. detection because they allow real-time, sensitive, high-throughput anal. Herein, we report an engineered biol. nanopore sensor by introducing a macrocyclic host mol. carboxylatopillar[5]arene (CP[5]A) that acts as an aptamer into the lumen of a mutant (E111R/K147R)7 αHL nanopore for detecting highly toxic paraquat (PQ) via host-guest interactions at the single-mol. level. By taking advantage of introducing pos. charged arginine (Arg) into the lumen of the αHL nanopore, our engineered nanopore sensor exhibits higher stability. More importantly, this nanopore sensor shows high sensitivity, and the limit of detection (LOD) for PQ can reach a nanomolar level of 0.37 ppb. The CP[5]A-based nanopore sensing strategy developed in this work may bring inspiration for single-mol. detection and hold great potential in public health applications. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Product Details of 150-78-7

The Article related to paraquat biosensor arginine hemolysin nanopore carboxylatopillararene, Biochemical Methods: Electrical and other aspects.Product Details of 150-78-7

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On December 16, 2008, Roy, Dhruvajyoti; Kwak, Ju-Won; Maeng, Wan Joo; Kim, Hyungjun; Park, Joon Won published an article.Formula: C6H12O3 The title of the article was Dendron-Modified Polystyrene Microtiter Plate: Surface Characterization with Picoforce AFM and Influence of Spacing between Immobilized Amyloid Beta Proteins. And the article contained the following:

A polystyrene microtiter plate was coated with a mol. layer of a cone-shaped dendron as a means of providing proper spacing between immobilized biomols. For the coating preparation, di(ethylene glycol) vinyl ether was grafted onto the surface of the microtiter plate by a plasma process followed by self-assembly of a second-generation dendron (9-acid) or a third-generation dendron (27-acid). Contact angle anal. revealed a pronounced increase in the hydrophilicity upon plasma grafting, while the hydrophilicity reverted/decreased after dendron immobilization. For anal. by force-based at. force microscopy (AFM), oligonucleotides were immobilized onto the AFM tip and the plate. The DNA-DNA interaction was observed at all spots examined, which implied that coating of the dendrons was uniform over the entire surface. The effectiveness for biomol. assays of the spacing on dendron-modified microtiter plates was examined by carrying out an ELISA, where enhanced detection of different fragments of amyloid beta protein (Aβ) was observed when compared with other conventional plates, such as untreated polystyrene or maleic anhydride activated plates. The pos. influence of the mesospacing between biomols. on the microtiter plates for this assay was confirmed. The experimental process involved the reaction of 2-(2-(Vinyloxy)ethoxy)ethanol(cas: 929-37-3).Formula: C6H12O3

The Article related to dendron modified polystyrene microtiter plate immobilized amyloid beta protein, Biochemical Methods: Apparatus and other aspects.Formula: C6H12O3

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On September 30, 2020, Alves, A. S.; de Moraes, M. M.; da Camara, C. A. G.; Lucena, M. F. A. published an article.Reference of 2-Methylanisole The title of the article was Chemical Composition of the Essential Oil of Cnidoscolus quercifolius from Brazil. And the article contained the following:

Cnidoscolus quercifolius (syn. Cnidoscolusphyllacanthus) belongs to the family Euphorbiaceae and is found exclusively in the Caatinga. To the best of our knowledge, C. quercifolius has not previously been investigated for the identification of the chemicalconstituents of its essential oils. This paper reports for the first time the chem. composition of essential oils from the leaves,flowers, and bark of C. quercifolius occurring in the Caatinga of Brazil. The essential oils obtained through conventional hydrodistillation of fresh leaves, flowers, and bark of C. quercifoliushad a light yellow color. The yield on a fresh weight basis was 0.01% for leaves, 0.03% for flowers, and 0.01% for bark.The oils were submitted to CG-MS for the determination of the constituents. Thirty-one, thirty, and eighteen compounds wereidentified in the essential oils from leaves, flowers, and bark, resp., accounting for 97.3%, 98.5%, and 81.4% of thetotal oils (Table 1). Diterpene was the predominant class of compounds in the leaf (44.6%) and bark (72.5%) oils, whereas monoterpenespredominated in the flower oil (95.5%). The major constituents identified in the leaf oil were phytol (42.1%), α-terpineol(10.9%), and 11,12-dihydroxyvalencene (7.8%). The major constituents identified in the flower oil were γ-terpinene (20.5%)and β-pinene (9.6%). The diterpenes dehydroabietal (29.9%) and abietadiene (21.4%) were the major constituents identifiedin the bark oil. These results suggest the chem. variability among the essentials oils from different organs of C. quercifolius. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Reference of 2-Methylanisole

The Article related to cnidoscolus essential oil isophytol polygodial chem composition, Placeholder for records without volume info and other aspects.Reference of 2-Methylanisole

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On April 13, 2020, Vasilevich, Anastasia V.; Baklanova, Olga N.; Lavrenov, Alexander V. published an article.Related Products of 91-16-7 The title of the article was Hydrodeoxygenation of Guaiacol with Molybdenum-Carbide-Based Carbon Catalysts. And the article contained the following:

Molybdenum carbide-based carbon materials were investigated as a catalyst for hydrodeoxygenation (HDO) of guaiacol. Mechanochem. synthesis has been used as a novel approach to obtain a fine molybdenum carbide-based carbon catalysts. Guaiacol was chosen as a bio-oil model compound to estimate the potential of the catalysts. The catalytic tests were carried out at 4 MPa initial hydrogen pressure, 320 °C for 180 min in a batch autoclave reactor. Insert abstract text here. A feed mixture was 3.5 g guaiacol in 66.5 g hexadecane as a solvent. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).Related Products of 91-16-7

The Article related to molybdenum carbide guaiacol hydrodeoxygenation carbon catalyst, Placeholder for records without volume info and other aspects.Related Products of 91-16-7

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On August 31, 2020, An, Jun-Nian; Qu, Wen-Juan; Zhang, Qin-Peng; Ma, Xiao-Qiang; Zhu, Wen-Bo; Zhang, You-Ming; Yao, Hong; Lin, Qi; Wei, Tai-Bao published an article.Computed Properties of 150-78-7 The title of the article was A pillar[5]arene-based supramolecular polymer network gel and its application in adsorption and removal of organic dye in water. And the article contained the following:

A novel 3D supramol. polymer network gel (DP5G) was successfully constructed by easy to synthesize tripodal guest (SZ) and thioacetylhydrazone functionalized di-pillar[5]arene host (DP5). Interestingly, the DP5G showed aggregation induced emission (AIE). Moreover, the DP5G displayed a 3D network structure, which was used to dye removal experiments Notably, the xerogel DP5G could effectively remove cationic dyes (including crystal violet and rhodamine B) from aqueous solution and the removal percentages are 96.3% and 95.4%, resp. In addition, the maximal adsorption capacity of DP5G towards crystal violet and rhodamine B are 19.65 mg/g and 22.85 mg/g, resp. The stability of the 3D supramol. polymer network gel (DP5G) was further investigated, which exhibited excellent stability toward outer stimuli such as pH, competitive agents, oxidant and reducing agent. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Computed Properties of 150-78-7

The Article related to pillar arene supramol polymer network gel organic dye removal, Placeholder for records without volume info and other aspects.Computed Properties of 150-78-7

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On July 31, 2022, DeCarlo, Anjanette; Agieb, Salah; Johnson, Stephen; Satyal, Prabodh; Setzer, William N. published an article.HPLC of Formula: 578-58-5 The title of the article was Inter-Tree Variation in the Chemical Composition of Boswellia papyrifera Oleo-Gum-Resin. And the article contained the following:

Frankincense is a fragrant resin produced by Boswellia species, and has been used for centuries as a perfume, medicine, and incense, and is an important cosmetic and therapeutic product today. A number of studies have been conducted on the resin essential oils, but many have used com. sources outside of the country of origin, leading to potential taxonomic confusion or misidentification. Individual Boswellia papyrifera resin samples were each obtained directly from 11 individual trees in Sudan, hydrodistd., the volatile phytochems. determined by gas chromatog. methods, and the chem. compositions subjected to cluster anal. All samples were very similar, with high levels of octyl acetate (49.5%-81.0%) and octanol (6.5%-13.7%), and varying levels of diterpenoids (6.6%-32.7%). The cluster anal. indicated 3 highly similar groups, defined by (1) relatively higher levels of octyl acetate (58.9%-81.0%), but with low levels of diterpenoids (6.6%-18.6%); (2) relatively lower levels of octyl acetate (49.5%-61.3%), but with a higher proportion of diterpenoids (19.0%-22.8%); and (3) with octyl acetate (51.6%) and diterpenoids (32.7%). The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).HPLC of Formula: 578-58-5

The Article related to boswellia oleo gum resin essential oil phytochem composition, Placeholder for records without volume info and other aspects.HPLC of Formula: 578-58-5

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On December 1, 2021, Liu, E.; Zhang, Qianfeng; Jian, Fangfang published an article.Recommanded Product: 91-16-7 The title of the article was Anthracene Cu(I) compounds with fluorescence and two-photon absorption properties. And the article contained the following:

A new ligand (L), 2-(2,3,6,7-tetramethoxy-9-(pyridin-2-yl)-9,10-dihydroanthracen-10-yl) pyridine, has been designed and synthesized. The anthracene ring in the ligand is curved and cannot form a large π bond conjugated system. Ligands have no fluorescence or other optical properties. When the ligand reacts with cuprous nitrate (CuNO3) to form complex (1), [LCuNO3], the anthracene ring magically straightens, and the maximum deviation of all the atoms on the anthracene ring from the anthracene ring plane is only 0.05873 Å. Complex (1) has a large two-photon absorption cross-sectional area and strong fluorescence properties. The nonlinear absorption of complex (1) (in DMF) was measured by the open-aperture Z-scan technique at a 532 nm wavelength. The results of Z-scan experiments show that complex (1) has remarkable nonlinear optical absorption effects with the two-photon absorption cross-section σ = 5969.78 GM. The ligand (L) and complex (1) all have certain thermal stability and their m.ps. are 169 °C for (L), and 297 °C for (1), resp. Their properties indicate that they have potential applications. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).Recommanded Product: 91-16-7

The Article related to anthracene copper complex fluorescence two photon absorption, Placeholder for records without volume info and other aspects.Recommanded Product: 91-16-7

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