Jiang, Xiaojia; Zang, Mingsong; Li, Fei; Hou, Chunxi; Luo, Quan; Xu, Jiayun; Liu, Junqiu published an article in 2021, the title of the article was Highly sensitive detection of paraquat with pillar[5]arenes as aptamer in alpa-hemolysin nanopore.Product Details of 150-78-7 And the article contains the following content:
Recently, biol. nanopore-based techniques have attracted more and more attention in the field of single-mol. detection because they allow real-time, sensitive, high-throughput anal. Herein, we report an engineered biol. nanopore sensor by introducing a macrocyclic host mol. carboxylatopillar[5]arene (CP[5]A) that acts as an aptamer into the lumen of a mutant (E111R/K147R)7 αHL nanopore for detecting highly toxic paraquat (PQ) via host-guest interactions at the single-mol. level. By taking advantage of introducing pos. charged arginine (Arg) into the lumen of the αHL nanopore, our engineered nanopore sensor exhibits higher stability. More importantly, this nanopore sensor shows high sensitivity, and the limit of detection (LOD) for PQ can reach a nanomolar level of 0.37 ppb. The CP[5]A-based nanopore sensing strategy developed in this work may bring inspiration for single-mol. detection and hold great potential in public health applications. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Product Details of 150-78-7
The Article related to paraquat biosensor arginine hemolysin nanopore carboxylatopillararene, Biochemical Methods: Electrical and other aspects.Product Details of 150-78-7
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem