Tag: 200-300

On December 19, 2009, Barry, Nicola; Brondel, Nicolas; Lawrence, Simon E.; Maguire, Anita R. published an article.Name: Benzyl(4-bromophenyl)sulfane The title of the article was Synthesis of aryl benzyl NH-sulfoximines. And the article contained the following:

Efficient synthesis and characterization of a series of aryl benzyl NH-sulfoximines are described. While N-protected versions of aryl benzyl sulfoximines have been previously described, reports of their deprotection are very limited, presumably due to lability under the typically harsh deprotection conditions which can be employed with the less reactive aryl alkyl derivatives Use of N-cyanosulfoximines as key intermediates overcomes these difficulties leading to an effective synthetic route to these compounds The experimental process involved the reaction of Benzyl(4-bromophenyl)sulfane(cas: 53136-21-3).Name: Benzyl(4-bromophenyl)sulfane

The Article related to aryl benzyl sulfoximine preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Others and other aspects.Name: Benzyl(4-bromophenyl)sulfane

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On October 31, 2021, Phetcharawetch, Jongkonporn; Betterley, Nolan M.; Reutrakul, Vichai; Soorukram, Darunee; Leowanawat, Pawaret; Kuhakarn, Chutima published an article.Related Products of 157869-15-3 The title of the article was Synthesis of 3-((trifluoromethyl)thio)indoles via trifluoromethylthiolation of 2-alkynyl azidoarenes with AgSCF3. And the article contained the following:

Direct and effective trifluoromethylthiolation of 2-alkynyl azidoarenes 2-CCR-4-R1-5-R2C6H2N3 (R = n-Bu, Ph, thiophen-2-yl, 2H-1,3-benzodioxol-5-yl, etc.; R1 = H, Me, Cl, CF3, etc.; R2 = H, Cl) with silver(I) trifluoromethanethiolate (AgSCF3) has been developed for the construction of 3-((trifluoromethyl)thio)indoles I. The trifluoromethylthiolation protocol is compatible with a broad substrate scope, providing a variety of 3-((trifluoromethyl)thio)indoles in moderate to good yields within one step, open-air, and short reaction time. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Related Products of 157869-15-3

The Article related to trifluoromethylthio indole preparation, alkynyl azidoarene silver trifluoromethanethiolate trifluoromethylthiolation, Heterocyclic Compounds (One Hetero Atom): Areno- and Diarenofurans and other aspects.Related Products of 157869-15-3

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On June 30, 2011, Hatano, Akihiko; Okada, Munehiro; Shimazaki, Kei; Uehara, Sanae; Ishikawa, Yuta; Matsumoto, Arata; Fujita, Yudai; Nishimura, Makoto published an article.COA of Formula: C13H11BrS The title of the article was Inhibitory effects on microbial growth using the derivatives of benzyl phenyl sulfide. And the article contained the following:

We investigated the antimicrobial activities of twelve derivatives of benzyl Ph sulfide by using Min. Inhibitory Concentration (MIC) and Min. Bactericidal Concentration (MBC) values against 10 microbial strains. These derivatives of benzyl Ph sulfides were synthesized by means of the nucleophilic coupling reaction at our laboratory MIC testing revealed that all synthetic derivatives of benzyl and 4-methoxybenzyl Ph sulfides had no effect against the tested microbial strains. However, the compounds of 4-nitrobenzyl Ph sulfide showed antimicrobial activity against many of the tested strains. Above all, 4-nitrobenzyl 4-chlorophenyl sulfide 11 exhibited the strongest and widest ranging inhibitory effects among the twelve synthetic compounds We researched the antimicrobial activities of the coupling materials of sulfide. As a result, it was considered important for the expression of antimicrobial activities that the sulfide had a 4-nitrobenzyl group and 4-chlorophenyl group in the same mol. as in the case of benzyl Ph sulfide. The experimental process involved the reaction of Benzyl(4-bromophenyl)sulfane(cas: 53136-21-3).COA of Formula: C13H11BrS

The Article related to benzyl phenyl sulfide growth inhibition, Microbial, Algal, and Fungal Biochemistry: Antimicrobial Sensitivity and other aspects.COA of Formula: C13H11BrS

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On November 6, 2015, Miranda, Luis D.; Hernandez-Vazquez, Eduardo published an article.Related Products of 887581-09-1 The title of the article was Multicomponent/Palladium-Catalyzed Cascade Entry to Benzopyrrolizidine Derivatives: Synthesis and Antioxidant Evaluation. And the article contained the following:

A versatile and efficient protocol for the synthesis of highly substituted benzopyrrolizidines (tetrahydro-3H-pyrrolo[2,1-a]isoindol-3-ones) is reported. The strategy consisted of an Ugi four-component reaction/elimination methodol. to afford dehydroalanines containing trans-cinnamic acid derivatives and different substituted 2-bromobenzylamines, followed by a palladium-catalyzed 5-exo-trig/5-exo-trig cascade carbocyclization process. Gratifyingly, benzopyrrolizidines, e.g. I, were obtained in moderate to good yields (42-77%) with a Z geometry due to the structural requirements for syn-β-hydride elimination. The prepared heterocyclic scaffolds are decorated with several substituents and incorporate a benzopyrrolizidine-fused system, along with an embedded cinnamic acid derivative, two privileged medicinal chem. scaffolds. Addnl., since some of the compounds are derived from the well-known antioxidants ferulic and sinapinic acids, they were tested for their in vitro antioxidant capacity. The data suggested that compounds having a p-hydroxyl group showed moderate 2,2-diphenyl-1-picrylhydrazyl-radical-scavenging activity and were effective antioxidants in preventing lipoperoxidation in a thiobarbituric acid reactive substances assay. The experimental process involved the reaction of (2-Bromo-5-methoxyphenyl)methanamine(cas: 887581-09-1).Related Products of 887581-09-1

The Article related to multicomponent ugi elimination palladium catalyst cascade carbocyclization, benzopyrrolizidine preparation antioxidant, Heterocyclic Compounds (One Hetero Atom): Pyrroles and Pyrrolizines and other aspects.Related Products of 887581-09-1

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Ether – Wikipedia,
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On September 3, 2015, Sherer, Brian; Brugger, Nadia published a patent.Reference of 3-(2-Methoxyphenoxy)benzaldehyde The title of the patent was Preparation of heterocyclic compounds as NaV channel inhibitors. And the patent contained the following:

The title compounds I [Z1 = CR2, C(O), C(S), C(NR); Z2 = CR2, O, S, SO, SO2, NR; X = O, S, SO2, SO, C(O), CO2, C(O)NR, NRC(O), NRC(O)NR, NRSO2, NR; or X is absent; A = (un)substituted alkyl, C5-10 aryl, 3-8 membered saturated or partially unsaturated carbocyclic ring, 3-7 membered heterocylic ring, or a 5-6 membered heteroaryl ring; R1 = R, halo, haloalkyl, etc.; R2-R5 = (independently) = H or alkyl; Y = CH2, O, S, SO2, SO, C(O), CO2, C(O)NR, NRC(O), NRC(O)NR, NRSO2, NR; B = (un)substituted C5-10 aryl or 5-6 membered heteroaryl ring; R6 = R, halo, haloalkyl, etc.; R = H, (un)substituted alkyl, C5-10 aryl, 3-8 membered saturated or partially unsaturated carbocyclic ring, 3-7 membered heterocylic ring having 1-4 heteroatoms selected from N, O, or S, or 5-6 membered monocyclic heteroaryl ring having 1-4 heteroatoms selected from N, O, or S; or two R groups on the same atom are taken together with the atom to which they are attached to form C3-10 aryl, 3-8 membered saturated or partially unsaturated carbocyclic ring, 3-7 membered heterocylic ring having 1-4 heteroatoms selected from N, O, or S, or 5-6 membered monocyclic heteroaryl ring having 1-4 heteroatoms selected from N, O, or S; m = 0-3; n = 0-3; q = 0-3; r = 1-2], useful as NaV1.6 inhibitors, were prepared and formulated. E.g., a multi-step synthesis of II, starting from pyrrolidine-1,3-dicarboxylic acid 1-tert-Bu ester and pyridin-2-yl-methylamine, was described. Exemplified compounds I were evaluated for their activity as NaV1.6 inhibitors (data given). The experimental process involved the reaction of 3-(2-Methoxyphenoxy)benzaldehyde(cas: 66855-92-3).Reference of 3-(2-Methoxyphenoxy)benzaldehyde

The Article related to heterocyclic compound pyrrolidinecarboxamide preparation sodium channel nav inhibitor, Heterocyclic Compounds (One Hetero Atom): Pyrroles and Pyrrolizines and other aspects.Reference of 3-(2-Methoxyphenoxy)benzaldehyde

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Xie, Yongtao; Zhou, Biying; Zhou, Sha; Zhou, Shaa; Wei, Wei; Liu, Jingbo; Zhan, Yizhou; Cheng, Dandan; Chen, Minggui; Li, Yuxin; Wang, Baolei; Xue, Xiao-song; Li, Zhengming published an article in 2017, the title of the article was Sulfimine-promoted fast O transfer: one-step synthesis of sulfoximine from sulfide.Application of 53136-21-3 And the article contains the following content:

Transfer of electrophilic NH to sulfides and a subsequent sulfimine-promoted fast O transfer was achieved in a one-pot process unprecedentedly for the preparation of sulfoximines, e.g., I at ambient temperature under air. The transformations, which are metal-, ligand-, base-, additive-free, and operationally simple, proceeded in just 5 min and furnished NH-sulfoximines in good-to-excellent yields (up to 99 %) by treatment of sulfides with a combination of PhI(OAc)2 and ammonia source. A variety of com. available and inexpensive electrophilic nitrogen sources were successfully used in the oxidative sulfide-to-sulfoximine conversions. This method featured a high efficiency, excellent functional-group tolerance, and broad substrate scope, which may facilitate its applications in medicinal chem. area. The experimental process involved the reaction of Benzyl(4-bromophenyl)sulfane(cas: 53136-21-3).Application of 53136-21-3

The Article related to sulfoximine preparation, sulfide iodobenzene diacetate ammonium carbonate imination, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Others and other aspects.Application of 53136-21-3

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Ether – Wikipedia,
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On June 30, 1999, Li, Xiao-Chang; Liu, Yunqi; Liu, Michelle S.; Jen, Alex K.-Y. published an article.Reference of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene The title of the article was Synthesis, Properties, and Application of New Luminescent Polymers with Both Hole and Electron Injection Abilities for Light-Emitting Devices. And the article contained the following:

New luminescent polymers that contain both electron-withdrawing cyano groups and electron-rich moieties, triphenylamine (TPA) or tetraphenyldiaminobiphenyl (TPD), were synthesized by Knoevenagel condensation of 1,4-bis(cyanomethyl)-2-[(2-ethylhexyl)oxy]-5-methoxybenzene with the dialdehyde of TPA or TPD, resp. The polymers were characterized by NMR, FT-IR, microanal., GPC, DSC, and TGA. Efficient orange photoluminescence was observed with an absolute quantum efficiency of 48% for the TPA incorporated polymer (TPA-CNPPV). Cyclic voltammetry investigation showed that the polymers presented reversible oxidation and reduction with relatively low potentials, which suggested that the polymers have both good electron and hole injection abilities. We demonstrated an effective approach to synthesize polymers with the triad properties of efficient photoluminescence, good hole injection and high electron-affinity properties, which are highly desirable for application in light-emitting devices. This point was supported by the demonstration of a single layer light-emitting device with a configuration of ITO/TPA-CNPPV/Al, in which good external quantum efficiency (0.1%) and bright luminance of 2100 cd/m2 was achieved. Multilayer LEDs using the polymers as the active layers and different charge injection/transporting layers were also investigated. The experimental process involved the reaction of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene(cas: 146370-51-6).Reference of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene

The Article related to luminescent polymer light emitting device, Chemistry of Synthetic High Polymers: Organic Addition Polymerization and other aspects.Reference of 1-((2-Ethylhexyl)oxy)-4-methoxybenzene

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On March 31, 2010, Klis, Tomasz; Serwatowski, Janusz; Wesela-Bauman, Grzegorz; Zadrozna, Magdalena published an article.Recommanded Product: 53136-21-3 The title of the article was Halogen-lithium exchange versus deprotonation: regioselective mono- and dilithiation of aryl benzyl sulfides. A simple approach to α,2-dilithiotoluene equivalents. And the article contained the following:

Halogen-lithium exchange and deprotonation reactions between aryl benzyl sulfides and alkyllithiums were investigated. The resultant mono- and dilithiated intermediates were converted into the corresponding aldehydes and boronic or carboxylic acids in good yields. It was found that di-Et ether stabilizes the ortho-lithiated compounds toward isomerization to the benzylic derivatives The process occurs easily in THF at low temperature and is a facile route to the α,2-dilithiotoluene derivative which can be transformed into a dicarboxylic acid on treatment with CO2. The experimental process involved the reaction of Benzyl(4-bromophenyl)sulfane(cas: 53136-21-3).Recommanded Product: 53136-21-3

The Article related to regioselective lithiation dilithiation aryl benzyl sulfide, halogen lithium exchange deprotonation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: General and other aspects.Recommanded Product: 53136-21-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Bard, Jeremy P.; Deng, Chun-Lin; Richardson, Hannah C.; Odulio, Jacob M.; Barker, Joshua E.; Zakharov, Lev N.; Cheong, Paul H.-Y.; Johnson, Darren W.; Haley, Michael M. published an article in 2019, the title of the article was Synthesis, photophysical properties, and self-dimerization studies of 2-λ5-phosphaquinolin-2-ones.Related Products of 157869-15-3 And the article contains the following content:

Authors have rationally designed and synthesized a library of phosphaquinolinone derivatives containing various electron-donating and -withdrawing groups on two positions of the scaffold. Distinct trends are observed between the substituents on R1 and R2 with both the photophys. properties of the mols. and their dimerization strengths. With withdrawing groups upon the scaffold, dimerization constants surpass 500 M-1 in H2O-saturated CDCl3. Computational studies on the dimeric structures corroborate the exptl. findings. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Related Products of 157869-15-3

The Article related to phosphaquinolinone preparation crystal mol structure photophysics dimerization, Organometallic and Organometalloidal Compounds: Phosphorus Compounds and other aspects.Related Products of 157869-15-3

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On March 5, 2021, Liu, Long; Tang, Yuanyuan; Wang, Kunyu; Huang, Tianzeng; Chen, Tieqiao published an article.HPLC of Formula: 53136-21-3 The title of the article was Transition-Metal-Free and Base-Promoted Carbon-Heteroatom Bond Formation via C-N Cleavage of Benzyl Ammonium Salts. And the article contained the following:

A facile and general method for constructing carbon-heteroatom (C-P, C-O, C-S, and C-N) bonds via C-N cleavage of benzyl ammonium salts under transition-metal-free conditions was reported. The combination of t-BuOK and 18-crown-6 enabled a wide range of substituted benzyl ammonium salts to couple readily with different kinds of heteroatom nucleophiles, i.e. hydrogen phosphoryl compounds, alcs., thiols, and amines. Good functional group tolerance was demonstrated. The scale-up reaction and one-pot synthesis were also successfully performed. The experimental process involved the reaction of Benzyl(4-bromophenyl)sulfane(cas: 53136-21-3).HPLC of Formula: 53136-21-3

The Article related to benzyl ammonium salt nucleophile bond formation potassium tert butoxide, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: General and other aspects.HPLC of Formula: 53136-21-3

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem