Tag: 200-300

Recommanded Product: 1,2-DiphenyldisulfaneIn 2019 ,《Catalyst-Free gem-Difunctionalization of Fluoroalkyl-Substituted Diazo Compound with Diselenide or Disulfide and NFSI》 was published in Organic Letters. The article was written by Li, Jiuling; Ma, Chaoqun; Xing, Dong; Hu, Wenhao. The article contains the following contents:

Diazo compounds such as F3CCH:N2 underwent difunctionalization reactions with diselenides, disulfides, or di-Ph ditelluride and N-fluorobenzenesulfonimide in CH2Cl2 to yield α-seleno-, α-thio-, or α-(phenyltelluro)alkylsulfonimides such as F3CCH(SePh)N(SO2Ph)2. Preliminary mechanistic studies indicate that a selenoimidate intermediate generated from diselenide and NFSI is involved for this transformation. The experimental part of the paper was very detailed, including the reaction process of 1,2-Diphenyldisulfane(cas: 882-33-7Recommanded Product: 1,2-Diphenyldisulfane)

1,2-Diphenyldisulfane(cas: 882-33-7) belongs to ethers.Ethers do have nonbonding electron pairs on their oxygen atoms, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Recommanded Product: 1,2-Diphenyldisulfane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Computed Properties of C12H10S2In 2020 ,《Cryogenic grinding performance of scrap tire rubber by devulcanization treatment with ScCO2》 was published in Powder Technology. The article was written by Li, Xiang; Xu, Xiaofei; Liu, Zhijun. The article contains the following contents:

The cryogenic grinding performance of scrap tire rubber modified by devulcanization treatment in supercritical carbon dioxide (ScCO2) was studied with a fluidized-bed jet mill. Scrap tire rubbers devulcanized with various concentrations of devulcanizing reagents were ground to analyze the effect of the degree of devulcanization on the particle size distribution of the ground product. Population balance modeling based on selection and breakage functions was adopted to explore the evolution rule of the particle sizes in the grinding process. The results of the cryogenic grinding experiment show that the devulcanization treatment can promote particle size reduction and lead to the transformation of the grinding mechanism from abrasion to cleavage or fracture. Furthermore, Kapur function fitted by the population balance modeling was proposed with a cubic polynomial, and the calculation results agreed well with the exptl. data. In addition to this study using 1,2-Diphenyldisulfane, there are many other studies that have used 1,2-Diphenyldisulfane(cas: 882-33-7Computed Properties of C12H10S2) was used in this study.

1,2-Diphenyldisulfane(cas: 882-33-7) belongs to ethers.Computed Properties of C12H10S2Although ethers resist hydrolysis, they are cleaved by hydrobromic acid and hydroiodic acid. Hydrogen chloride cleaves ethers only slowly.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Dudko, Volodymyr; Ottermann, Katharina; Rosenfeldt, Sabine; Papastavrou, Georg; Breu, Josef published an article in 2021. The article was titled 《Osmotic delamination: Forceless alternative for production of nanosheets now in highly polar and aprotic solvents》, and you may find the article in Langmuir.Recommanded Product: 1,4,7,10,13-Pentaoxacyclopentadecane The information in the text is summarized as follows:

Repulsive osmotic delamination is thermodynamically allowed “”dissolution”” of two-dimensional (2D) materials and therefore represents an attractive alternative to liquid-phase exfoliation to obtain strictly monolayered nanosheets with an appreciable aspect ratio with quant. yield. However, osmotic delamination was so far restricted to aqueous media, severely limiting the range of accessible 2D materials. Alkali-metal intercalation compounds of MoS2 or graphite are excluded because they cannot tolerate even traces of water. We now succeeded in extending osmotic delamination to polar and aprotic organic solvents. Upon complexation of interlayer cations of synthetic hectorite clay by crown ethers, either 15-crown-5 or 18-crown-6, steric pressure is exerted, which helps in reaching the threshold separation required to trigger osmotic delamination based on translational entropy. This way, complete delamination in water-free solvents like aprotic ethylene and propylene carbonate, N-methylformamide, N-methylacetamide, and glycerol carbonate was achieved. In the experimental materials used by the author, we found 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Recommanded Product: 1,4,7,10,13-Pentaoxacyclopentadecane)

1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Recommanded Product: 1,4,7,10,13-Pentaoxacyclopentadecane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

SDS of cas: 139115-91-6In 2021 ,《Conjugate of thiol and guanidyl units with oligoethylene glycol linkage for manipulation of oxidative protein folding》 was published in Molecules. The article was written by Okada, Shunsuke; Matsusaki, Motonori; Okumura, Masaki; Muraoka, Takahiro. The article contains the following contents:

Oxidative protein folding is a biol. process to obtain a native conformation of a protein through disulfide-bond formation between cysteine residues. In a cell, disulfide-catalysts such as protein disulfide isomerase promote the oxidative protein folding. Inspired by the active sites of the disulfide-catalysts, synthetic redox-active thiol compounds have been developed, which have shown significant promotion of the folding processes. In our previous study, coupling effects of a thiol group and guanidyl unit on the folding promotion were reported. Herein, we investigated the influences of a spacer between the thiol group and guanidyl unit. A conjugate between thiol and guanidyl units with a diethylene glycol spacer (GdnDEG-SH) showed lower folding promotion effect compared to the thiol-guanidyl conjugate without the spacer (GdnSH). Lower acidity and a more reductive property of the thiol group of GdnDEG-SH compared to those of GdnSH likely resulted in the reduced efficiency of the folding promotion. Thus, the spacer between the thiol and guanidyl groups is critical for the promotion of oxidative protein folding. The experimental part of the paper was very detailed, including the reaction process of tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6SDS of cas: 139115-91-6)

tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6) belongs to ethers.Oxygen is more electronegative than carbon, thus the alpha hydrogens of ethers are more acidic than those of simple hydrocarbons. They are far less acidic than alpha hydrogens of carbonyl groups (such as in ketones or aldehydes), however. SDS of cas: 139115-91-6

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Reference of Bis(4-methoxyphenyl)amineIn 2019 ,《Synthesis, photophysical and electronic properties of tetra-donor- or acceptor-substituted ortho-perylenes displaying four reversible oxidations or reductions》 was published in Chemical Science. The article was written by Merz, Julia; Steffen, Andreas; Nitsch, Joern; Fink, Julian; Schuerger, Claudia B.; Friedrich, Alexandra; Krummenacher, Ivo; Braunschweig, Holger; Moos, Michael; Mims, David; Lambert, Christoph; Marder, Todd B.. The article contains the following contents:

(DPA)4-Per I and (Bmes2)4-Per II derivatives were synthesized via regioselective Ir-catalyzed C-H borylation and subsequent reactions, a strong π-donors and acceptors at the 2,5,8,11-positions of perylene were introduced leading to unusual properties. Thus, incorporation of four donor diphenylamine (DPA) or four acceptor Bmes2 (mes = 2,4,6-Me3C6H2) moieties yielded novel compounds which can be reversibly oxidized or reduced four times, resp., an unprecedented behavior for monomeric perylene derivatives Spectroelectrochem. measurements showed NIR absorptions up to 3000 nm for the mono-cation radical of II and a strong electronic coupling over the perylene bridge was observed indicative of fully delocalized Robin-Day Class III behavior. Both derivatives I and II possess unusually long intrinsic singlet lifetimes (τ0), e.g., 94 ns for the former one. The compounds I and II were emissive in solution, thin films, and the solid state, with apparent Stokes shifts were exceptionally large for perylene derivatives Transient absorption measurements on II revealed an addnl. excited state, with a long lifetime of 500μs, which sensitized singlet oxygen effectively. The experimental process involved the reaction of Bis(4-methoxyphenyl)amine(cas: 101-70-2Reference of Bis(4-methoxyphenyl)amine)

Bis(4-methoxyphenyl)amine(cas: 101-70-2) is a diphenylamine derivative used as a chemical additive for cured rubber.Bis(4-methoxyphenyl)amine is highly toxic and may potentially induce chromosome abberation.Reference of Bis(4-methoxyphenyl)amine

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Rosendale, Morgane; Daniel, Jonathan; Castet, Frederic; Pagano, Paolo; Verlhac, Jean-Baptiste; Blanchard-Desce, Mireille published an article in Molecules. The title of the article was 《Stealth Luminescent Organic Nanoparticles Made from Quadrupolar Dyes for Two-Photon Bioimaging: Effect of End-Groups and Core》.Quality Control of Bis(4-methoxyphenyl)amine The author mentioned the following in the article:

Mol.-based Fluorescent Organic Nanoparticles (FONs) are versatile light-emitting nano-tools whose properties can be rationally addressed by bottom-up mol. engineering. A challenging property to gain control over is the interaction of the FONs′ surface with biol. systems. Indeed, most types of nanoparticles tend to interact with biol. membranes. To address this limitation, we recently reported on two-photon (2P) absorbing, red to near IR (NIR) emitting quadrupolar extended dyes built from a benzothiadiazole core and diphenylamino endgroups that yield spontaneously stealth FONs. In this paper, we expand our understanding of the structure-property relationship between the dye structure and the FONs 2P absorption response, fluorescence and stealthiness by characterizing a dye-related series of FONs. We observe that increasing the strength of the donor end-groups or of the core acceptor in the quadrupolar (D-π-A-π-D) dye structure allows for the tuning of optical properties, notably red-shifting both the emission (from red to NIR) and 2P absorption spectra while inducing a decrease in their fluorescence quantum yield. Thanks to their strong 1P and 2P absorption, all FONs whose median size varies between 11 and 28 nm exhibit giant 1P (106 M-1.cm-1) and 2P (104 GM) brightness values. Interestingly, all FONs were found to be non-toxic, exhibit stealth behavior, and show vanishing non-specific interactions with cell membranes. We postulate that the strong hydrophobic character and the rigidity of the FONs building blocks are crucial to controlling the stealth nano-bio interface. After reading the article, we found that the author used Bis(4-methoxyphenyl)amine(cas: 101-70-2Quality Control of Bis(4-methoxyphenyl)amine)

Bis(4-methoxyphenyl)amine(cas: 101-70-2) is a diphenylamine derivative used as a chemical additive for cured rubber.Bis(4-methoxyphenyl)amine is highly toxic and may potentially induce chromosome abberation.Quality Control of Bis(4-methoxyphenyl)amine

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Chen, Hongyi; Chen, Li; He, Ze; Zeng, Qingle published their research in Green Chemistry in 2021. The article was titled 《Blue light-promoted radical sulfoximido-chalcogenization of aliphatic and aromatic alkenes》.Application In Synthesis of 1,2-Diphenyldisulfane The article contains the following contents:

A transition metal-free synthesis of N-(arylthio/seleno)ethyl sulfoxidmines via blue light-promoted radical sulfoximido-chalcogenization of aliphatic and aromatic alkenes was developed. The sulfoximidation process demonstrated high chemoselectivity and allowed a broad substrate scope, completing the sulfoximido-chalcogenization of alkenes in good yields. In the experimental materials used by the author, we found 1,2-Diphenyldisulfane(cas: 882-33-7Application In Synthesis of 1,2-Diphenyldisulfane)

1,2-Diphenyldisulfane(cas: 882-33-7) belongs to ethers.Oxygen is more electronegative than carbon, thus the alpha hydrogens of ethers are more acidic than those of simple hydrocarbons. They are far less acidic than alpha hydrogens of carbonyl groups (such as in ketones or aldehydes), however. Application In Synthesis of 1,2-Diphenyldisulfane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Solvent switchable Pd/DNA catalyst in carbonylative Sonogashira coupling》 was published in Molecular Catalysis in 2020. These research results belong to Mart, M.; Trzeciak, A. M.. HPLC of Formula: 529-28-2 The article mentions the following:

Palladium catalysts immobilized on DNA (Pd/DNA) were applied for the first time in the carbonylative Sonogashira coupling, at 1 atm of CO. Different alkynones were obtained with a high yield in DMF. In the presence of water, the selectivity completely changed and diaryl alkynes, typical Sonogashira products, were selectively formed. In addition to Pd/DNA, soluble palladium species also participated in the catalytic process. The stability of the catalytic system increased after the addition of DNA excess. In addition to this study using 1-Iodo-2-methoxybenzene, there are many other studies that have used 1-Iodo-2-methoxybenzene(cas: 529-28-2HPLC of Formula: 529-28-2) was used in this study.

1-Iodo-2-methoxybenzene(cas: 529-28-2) is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.HPLC of Formula: 529-28-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Sulfonamide Directivity Enables Ni-Catalyzed 1,2-Diarylation of Diverse Alkenyl Amines》 was published in ACS Catalysis in 2020. These research results belong to Apolinar, Omar; Tran, Van T.; Kim, Nana; Schmidt, Michael A.; Derosa, Joseph; Engle, Keary M.. HPLC of Formula: 529-28-2 The article mentions the following:

1,2-Diarylation of alkenyl sulfonamides with aryl iodides and aryl boronic esters under nickel catalysis is reported. The developed method tolerates coupling partners with disparate electronic properties and substitution patterns. Di- and trisubstituted alkenes as well as alkenes distal from the directing group are all accommodated. Control experiments are consistent with a N-Ni coordination mode of the directing group, which stands in contrast to a previous report on amide-directed 1,2-diarylation, which involves carbonyl coordination. The synthetic utility of the method arises from the dual function of the sulfonamide as both a directing group and a masked amine nucleophile. This is highlighted by various product diversifications where complex amine compounds are synthesized in a two-step sequence of N-functionalization and deprotection of the sulfonyl group. The experimental process involved the reaction of 1-Iodo-2-methoxybenzene(cas: 529-28-2HPLC of Formula: 529-28-2)

1-Iodo-2-methoxybenzene(cas: 529-28-2) is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.HPLC of Formula: 529-28-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

The author of 《Ortho/Ipso Alkylborylation of Aryl Iodides》 were Sui, Xianwei; Grigolo, Thiago A.; O’Connor, Colin J.; Smith, Joel M.. And the article was published in Organic Letters in 2019. Application In Synthesis of 1-Iodo-2-methoxybenzene The author mentioned the following in the article:

This work describes a method for the difunctionalization of aryl iodides to generate polysubstituted arenes via Pd catalysis. The reaction hinges on the unique interplay between norbornene and the metal catalyst to impart a guided ortho C-H alkylation event followed by a programmatic ipso borylation to provide a diverse array of substituted arene products. The utility of this transformation is demonstrated through the functionalization of the boronic ester to a variety of valuable functionalities. In the experiment, the researchers used many compounds, for example, 1-Iodo-2-methoxybenzene(cas: 529-28-2Application In Synthesis of 1-Iodo-2-methoxybenzene)

1-Iodo-2-methoxybenzene(cas: 529-28-2) participates in palladium catalyzed enantioselective Heck arylation of 2,3-dihydrofuran in the presence of chiral ionic liquids containing L-prolinate and L-lactate anions and non-chiral quaternary ammonium cations.Application In Synthesis of 1-Iodo-2-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem