200-300 Archives - Page 18 of 177 - Ethers-buliding-blocks

de Lucca, Anthony J. et al. published their research in Annals of Agricultural and Environmental Medicine in 2010 | CAS: 20324-33-8

1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol (cas: 20324-33-8) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Safety of 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol

Volatile profiles of toxigenic and non-toxigenic Aspergillus flavus using SPME for solid phase extraction was written by de Lucca, Anthony J.;Boue, Stephen M.;Carter-Wientjes, Carol H.;Bland, John M.;Bhatnagar, Deepak;Cleveland, Thomas E.. And the article was included in Annals of Agricultural and Environmental Medicine in 2010.Safety of 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol This article mentions the following:

Toxigenic and atoxigenic strains of Aspergillus flavus were grown on potato dextrose agar (PDA) and wetted (23% moisture) sterile, cracked corn for 14 and 21 days, resp. Volatile compounds produced by A. flavus, as well as those present in the PDA controls and sterile cracked maize, were collected using solid-phase micro-extraction (SPME) and identified by gas chromatog./mass spectrometry. Results show that growth substrate had a major impact on the number and type of volatiles detected. Growth on sterile cracked maize produced many more volatiles than did potato dextrose agar. There were also differences observed in the type of volatiles produced between toxigenic and non-toxigenic isolates, as well as between isolates of the same toxigenic grouping. In the experiment, the researchers used many compounds, for example, 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol (cas: 20324-33-8Safety of 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol).

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Gu, Xue Ping et al. published their research in Journal of Organic Chemistry in 1986 | CAS: 60221-37-6

2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol (cas: 60221-37-6) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Safety of 2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol

2-Chloro-1-(chloromethyl)ethyl methoxymethyl ether as a reagent for acetonylation of alcohols and phenol was written by Gu, Xue Ping;Ikeda, Isao;Komada, Satoru;Masuyama, Araki;Okahara, Mitsuo. And the article was included in Journal of Organic Chemistry in 1986.Safety of 2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol This article mentions the following:

Treatment of ROH [R = decyl, cyclohexyl, Ph, Me₃C, Me(CH₂)₉OCH₂(CH₂OCH₂)₃CH₂OH, etc.] with ClCH₂CH(CH₂Cl)OCH₂OMe (I), Bu₄N⁺ HSO₄^–, and a base (e.g., NaOH) gave ROCH₂C(:CH₂)OCH₂OMe, which were treated with aqueous H₂SO₄ to give 42-83% ROCH₂COMe. Similar treatment of HOCH₂(CH₂OCH₂)₂CH₂OH with I, but without Bu₄N⁺ HSO₄^–, gave 61% MeCOCH₂OCH₂(CH₂OCH₂)₂CH₂OCH₂COMe. In the experiment, the researchers used many compounds, for example, 2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol (cas: 60221-37-6Safety of 2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol).

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Caldeira, M. et al. published their research in Journal of Chromatography A in 2011 | CAS: 20324-33-8

1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol (cas: 20324-33-8) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Category: ethers-buliding-blocks

Profiling allergic asthma volatile metabolic patterns using a headspace-solid phase microextraction/gas chromatography based methodology was written by Caldeira, M.;Barros, A. S.;Bilelo, M. J.;Parada, A.;Camara, J. S.;Rocha, S. M.. And the article was included in Journal of Chromatography A in 2011.Category: ethers-buliding-blocks This article mentions the following:

Allergic asthma represents an important public health issue with significant growth over the years, especially in the pediatric population. Exhaled breath is a non-invasive, easily performed and rapid method for obtaining samples from the lower respiratory tract. In the present manuscript, the metabolic volatile profiles of allergic asthma and control children were evaluated by headspace solid-phase microextraction combined with gas chromatog.-quadrupole mass spectrometry (HS-SPME/GC-qMS). The lack of studies in breath of allergic asthmatic children by HS-SPME led to the development of an exptl. design to optimize SPME parameters. To fulfil this objective, three important HS-SPME exptl. parameters that influence the extraction efficiency, namely fiber coating, temperature and time extractions were considered. The selected conditions that promoted higher extraction efficiency corresponding to the higher GC peak areas and number of compounds were: DVB/CAR/PDMS coating fiber, 22° and 60 min as the extraction temperature and time, resp. The suitability of two containers, 1 L Tedlar bags and BIOVOC for breath collection and intra-individual variability were also investigated. The developed methodol. was then applied to the anal. of children exhaled breath with allergic asthma (35), from which 13 had also allergic rhinitis, and healthy control children (15), allowing to identify 44 volatiles distributed over the chem. families of alkanes (linear and ramified) ketones, aromatic hydrocarbons, aldehydes, acids, among others. Multivariate studies were performed by Partial Least Squares-Discriminant Anal. (PLS-DA) using a set of 28 selected metabolites and discrimination between allergic asthma and control children was attained with a classification rate of 88%. The allergic asthma pediatric population was characterized mainly by the compounds linked to oxidative stress, such as alkanes and aldehydes. Furthermore, more detailed information was achieved combining the volatile metabolic data, suggested by PLS-DA model, and clin. data. In the experiment, the researchers used many compounds, for example, 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol (cas: 20324-33-8Category: ethers-buliding-blocks).

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Shideman, F. E. et al. published their research in Journal of Pharmacology and Experimental Therapeutics in 1951 | CAS: 20324-33-8

1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol (cas: 20324-33-8) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Recommanded Product: 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol

Pharmacology of the monomethyl ethers of mono-, di-, and tripropylene glycol in the dog with observations of the auricular fibrillation produced by these compounds was written by Shideman, F. E.;Procita, Leonard. And the article was included in Journal of Pharmacology and Experimental Therapeutics in 1951.Recommanded Product: 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol This article mentions the following:

In dogs, the above compounds are central nervous system and cardiac depressants of low toxicity. Death in the intact animal results from respiratory failure. In the anesthetized, artificially respired dog appropriate intravenous doses consistently produce auricular fibrillation. Auricular anoxia, depressed conduction and heart block with ventricular asystole, and increased intra-auricular pressure all appear to be important factors in production of this arrhythmia. In the experiment, the researchers used many compounds, for example, 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol (cas: 20324-33-8Recommanded Product: 1-((1-((1-Methoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol).

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Eustathopoulos, Helene et al. published their research in Journal of the Chemical Society in 1983 | CAS: 75581-11-2

4-Iodo-1-methoxy-2-methylbenzene (cas: 75581-11-2) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Quality Control of 4-Iodo-1-methoxy-2-methylbenzene

Ambident reactivity of anisole and p-iodoanisole toward phenylium cations and evidence for ipso-attack in cationic phenylation was written by Eustathopoulos, Helene;Court, Jean;Bonnier, Jane Marie. And the article was included in Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) in 1983.Quality Control of 4-Iodo-1-methoxy-2-methylbenzene This article mentions the following:

The phenylation of p-IC₆H₄OMe in the thermolysis of PhN₂BF₄ gave, inter alia,p-MeOC₆H₄Ph and 4-IC₆H₄OPh, showing ipso-attack and attack on O by Ph⁺. With PhOMe, the O atom of the MeO substituent is also attacked by Ph⁺ giving Ph₂O through the initial formation of Ph₂O⁺Me followed by intermol. demethylation. No intramol. rearrangement occurs with the oxonium ion. The mechanism involves kinetically predominant C-phenylation of both substrates. BF₃ promotes deiodination of p-IC₆H₄OMe and its phenylated isomers. This deiodination invalidates the conclusions drawn from isomer distributions; therefore the presence of BF₃ must be carefully controlled in a mechanistic study. In the experiment, the researchers used many compounds, for example, 4-Iodo-1-methoxy-2-methylbenzene (cas: 75581-11-2Quality Control of 4-Iodo-1-methoxy-2-methylbenzene).

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

de Lucca, Anthony J. et al. published their research in Annals of Agricultural and Environmental Medicine in 2010 | CAS: 20324-33-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Liu, Tongqing et al. published their research in Wuli Huaxue Xuebao in 2020 | CAS: 6972-61-8

3-(2,4-Dimethoxyphenyl)acrylic acid (cas: 6972-61-8) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Product Details of 6972-61-8

Structure-property relationship of light-responsive wormlike micelles using methoxycinnamate derivatives as light-switchable molecules was written by Liu, Tongqing;Xue, Fangfang;Yi, Ping;Xia, Zhiyu;Dong, Jinfeng;Li, Xuefeng. And the article was included in Wuli Huaxue Xuebao in 2020.Product Details of 6972-61-8 This article mentions the following:

In this work, light-responsive viscoelastic wormlike micelles based on cetyltrimethylammonium hydroxide (CTAOH) and cinnamic acid derivatives, including cinnamic acid (CA), 2-methoxycinnamic acid (2-MCA), 3-methoxycinnamic acid (3-MCA), 4-methoxycinnamic acid (4-MCA), 2,3-dimethoxycinnamic acid (2,3-DMCA), 2,4-dimethoxycinnamic acid (2,4-DMCA), 2,3,4-trimethoxycinnamic acid (2,3,4-DMCA), and 3,4,5-trimethoxycinnamic acid (3,4,5-DMCA), were prepared The effects of the CA derivative structures, especially the position and number of methoxy moieties, on the formation of wormlike micelles were systematically determined The CA derivatives facilitated the formation of long and entangled wormlike micelles. ¹H NMR results showed that the CA derivatives participated in the formation of wormlike micelles via insertion of the aromatic moieties into the aggregates. The number of methoxy moieties had a much stronger effect on the viscosity of the wormlike micelle solution than the position of this moiety. The larger the number of methoxy moiety, the smaller was the aggregate. Substituted methoxy moieties increased the steric hindrance between the surfactants and CA mols., thus hindering the formation of large aggregates. However, the position of the methoxy moiety had a predominant effect on the UV-light-induced transition of the wormlike micelles. Specifically, the ortho-methoxy moiety in the CA mols. dramatically enhanced the efficiency of UV-light-induced trans-cis isomerization. For example, the 2-MCA/CTAOH, 3-MCA/CTAOH, and 4-MCA/CTAOH binary systems (90 mmol·L^-1/100 mmol·L^-1) were gel-like with similar viscosities of around 20 Pa·s, but after UV light irradiation, they were transformed into a fluid with lower viscosity because of the formation of smaller aggregates. However, the irradiation time required for the transition varied significantly, as suggested by the results of viscosity measurements and UV-Vis spectroscopy. The 2-MCA/CTAOH system underwent complete phase transition within 3 h, whereas continuous transitions were observed for the 3-MCA/CTAOH and 4-MCA/CTAOH systems upon irradiation for 24 h. ¹H NMR results suggested that the change in the configuration of MCA in the micelles before and after irradiation was the major cause of the abovementioned difference in the phase transition pattern. Initially, all the aromatic moieties of the trans-2-MCA mols. were deeply inserted into the hydrophobic cores of the micelles in a vertical manner, and the ionized carboxyl moiety was located in the palisade layer because of the electrostatic interactions between CTAOH and trans-2-MCA. In contrast, cis-2-MCA was inserted into the micelles in a horizontal manner, and some of the protons in the aromatic moiety were also transferred from the micellar core to the polar palisade layer. Accordingly, the CTAOH and cis-2-MCA mols. were packed loosely in the aggregates, thereby resulting in the formation of spherical micelles. Similar UV-light-induced transitions were observed for the 3-MCA/CTAOH and 4-MCA/CTAOH systems. In the experiment, the researchers used many compounds, for example, 3-(2,4-Dimethoxyphenyl)acrylic acid (cas: 6972-61-8Product Details of 6972-61-8).

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Gorski, R. J. et al. published their research in Journal of Chromatography in 1991 | CAS: 1132-95-2

1,1-Diisopropoxycyclohexane (cas: 1132-95-2) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Reference of 1132-95-2

Estimation and identification of non-polar compounds in clarithromycin bulk drug by high-performance liquid chromatography was written by Gorski, R. J.;Morgan, D. K.;Sarocka, C.;Plasz, A. C.. And the article was included in Journal of Chromatography in 1991.Reference of 1132-95-2 This article mentions the following:

A HPLC method was developed to estimate and identify the non-polar related substances and process impurities that elute after N-dimethyl-N-formyl-6-O-methylerythromycin A in clarithromycin (I) bulk drug. This method separates at least 15 compounds from the I peak. All of the non-polar compounds can be detected at the 0.02% (weight/weight) level. Five bulk drug lots were examined for late-eluting compounds The total related substances ranged from <0.10 to <0.25%. In the experiment, the researchers used many compounds, for example, 1,1-Diisopropoxycyclohexane (cas: 1132-95-2Reference of 1132-95-2).

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Hameed, Nishar et al. published their research in ACS Applied Polymer Materials in 2020 | CAS: 66943-05-3

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Quality Control of 1,4,7,10-Tetraoxa-13-azacyclopentadecane

Rapid Crosslinking of Epoxy Thermosets Induced by Solvate Ionic Liquids was written by Hameed, Nishar;Eyckens, Daniel J.;Long, Benjamin M.;Salim, Nisa V.;Capricho, Jaworski C.;Servinis, Linden;De Souza, Mandy;Perus, Magenta D.;Varley, Russell J.;Henderson, Luke C.. And the article was included in ACS Applied Polymer Materials in 2020.Quality Control of 1,4,7,10-Tetraoxa-13-azacyclopentadecane This article mentions the following:

The high-volume manufacture of fiber-reinforced composites faces a huge challenge because long resin curing times put a low ceiling on the total output of parts produced per yr. To translate the benefits from using epoxy in large-volume production platforms, cure cycle times of less than 1 min must be achieved. In this work, we report solvate ionic liquids (SILs) as simple and efficient rapid curing catalytic additives in epoxy systems. Ultrafast curing was observed at low levels of 1-5% of SIL in epoxy resin, and the cure rate is enhanced up to 26-fold without compromising the mech. and thermal properties. Further investigations revealed that enhancement in the cure rate is dependent on the type of SILs employed, influenced by the metal center, the ligands around the metal, and the identity of the counter anion. The relative Lewis acidity of each of the active complexes was calculated, and the rapid cure effect was attributed to the activation of the epoxide moiety via the Lewis acidic nature of the SIL. Making epoxy thermosets rapidly processable enables enormous benefits, finding applications in a whole variety of transformation methods that exist for traditional glass and metals. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3Quality Control of 1,4,7,10-Tetraoxa-13-azacyclopentadecane).

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Guerrand, Helene D. S. et al. published their research in Chemistry – A European Journal in 2014 | CAS: 365564-07-4

2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 365564-07-4) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Related Products of 365564-07-4

Borylation of Unactivated Aryl Chlorides under Mild Conditions by Using Diisopropylaminoborane as a Borylating Reagent was written by Guerrand, Helene D. S.;Marciasini, Ludovic D.;Jousseaume, Melissa;Vaultier, Michel;Pucheault, Mathieu. And the article was included in Chemistry – A European Journal in 2014.Related Products of 365564-07-4 This article mentions the following:

The synthesis of arylboronic ester derivatives from aryl chlorides by using aryl(amino)boranes is described. Palladium-catalyzed coupling between aryl chlorides and diisopropylaminoborane leads to the formation of a C-B bond under mild conditions. A wide range of functional groups are tolerated, making this method particularly useful for the borylation of functionalized aromatics In the experiment, the researchers used many compounds, for example, 2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 365564-07-4Related Products of 365564-07-4).

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem