Tag: M.W=150-200

Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid. Then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. Related Products of 122775-35-3.

Koszelewski, Dominik;Paprocki, Daniel;Brodzka, Anna;Keciek, Aleksandra;Wilk, Monika;Ostaszewski, Ryszard research published �The sustainable copper-catalyzed direct formation of highly functionalized p-quinols in water� the research content is summarized as follows. The straightforward copper-catalyzed formation of p-quinols in water under air has been accomplished employing arylboronic acids. Various substituted p-benzoquinol derivatives of biol. importance were obtained in good yield. Furthermore, the synthesis of target p-quinols under physiol. conditions in serum and carbonate buffer is demonstrated. The essential features of this method are the high functional group tolerance and scalable one-pot preparation of p-quinols from corresponding arylboronic acid. Very mild reaction conditions, an absence of the heavy toxic metals, simple procedure as well as high chemoselectivity makes the established protocol desirable for academia and pharmaceutical industry laboratories

Related Products of 122775-35-3, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., 122775-35-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. Reference of 122775-35-3.

Kuleshova, Olena;Asako, Sobi;Ilies, Laurean research published �Ligand-Enabled, Iridium-Catalyzed ortho-Borylation of Fluoroarenes� the research content is summarized as follows. A terpyridine derivative and an iridium complex catalyze the C-H borylation of a stoichiometric amount of a fluoroarene with high ortho-selectivity and tolerance of functional groups such as bromide, chloride, ester, ketone, amine, and in situ-borylated hydroxyl. Complex drug mols. such as haloperidol can be selectively borylated ortho to the F atom. The terpyridine ligand undergoes rollover cyclometalation to produce an N,N,C-coordinated iridium complex, which may either selectively borylate the fluoroarene by itself or undergo reductive elimination to produce a borylated ligand.

Reference of 122775-35-3, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., 122775-35-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid.They have the general formula R–O–Râ€? where R and Râ€?represent the alkyl or aryl groups. Quality Control of 122775-35-3.

Kurpik, Gracjan;Walczak, Anna;Gilski, Miroslaw;Harrowfield, Jack;Stefankiewicz, Artur R. research published ã€?Effect of the nuclearity on the catalytic performance of a series of Pd(II) complexes in the Suzuki-Miyaura reactionã€? the research content is summarized as follows. Development of well-defined multivalent systems with densely packed multiple functional groups located within a single mol. structure provides an excellent opportunity to generate catalysts of enhanced activity. A series of mono-, di- and trinuclear Pd(II) complexes based on polyketonate ligands allied with 2,2′-bipyridine was designed, synthesized and fully characterized in both solution and solid state. The mono-, di- and tritopic β-diketonate mols. serve as scaffolds for Pd(II) active sites which, in the two latter cases, are forced into close proximity. Application of the complexes as catalysts in Suzuki-Miyaura cross-coupling as a model reaction revealed significant differences in reaction yields and a trend in reactivity reflecting their nuclearity.

Quality Control of 122775-35-3, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., 122775-35-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid.They have the general formula R–O–Râ€? where R and Râ€?represent the alkyl or aryl groups. Electric Literature of 122775-35-3.

Laha, Joydev K.;Gulati, Upma;Saima;Schulte, Tim;Breugst, Martin research published ã€?pH-Controlled Intramolecular Decarboxylative Cyclization of Biarylacetic Acids: Implication on Umpolung Reactivity of Aroyl Radicalsã€? the research content is summarized as follows. A simple approach for the intramol. aroylation of electron-rich arenes 2-RC₆H₄CH₂C(O)OH (R = Ph, 2,5-dimethylphenyl, naphthalen-2-yl, etc.) under mild conditions has been developed. A pH-controlled polarity umpolung strategy can be used to synthesize different fluorenones I (R¹ = H, Me, OMe, F, Cl, CF₃; R² = H, OMe, CF₃, F, etc.; R¹R² = – CH:CHCH:CH-; R³ = H, Me, OMe, Cl; R⁴ = F, CF₃), which are important building blocks for biol. applications. Unlike previous acylation reactions involving nucleophilic aroyl radicals, this approach likely relies on in situ generated electrophilic aroyl radicals. Detailed mechanistic and computational investigations provide detailed insights into the reaction mechanism and support the hypothesis of a pH-mediated umpolung.

122775-35-3, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., Electric Literature of 122775-35-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Recommanded Product: 3,4-Dimethoxyphenylboronic acid.

Khorsandi, Zahra;Metkazini, S. Fatemeh Mohammadi;Heydari, Akbar;Varma, Rajender S. research published 《 Visible light-driven direct synthesis of ketones from aldehydes via C-H bond activation using NiCu nanoparticles adorned on carbon nano onions》, the research content is summarized as follows. An efficient, straightforward and high yield synthetic approach is described for the direct synthesis of diaryl ketones via the C-H bond activation of aldehydes using Ni-Cu nanoparticles adorned on carbon nano onions as an efficient heterogeneous catalyst under the irradiation of a mercury-vapor lamp (400 w) via simple workup. This C-H bond activation reaction appears simple and convenient with a wide substrate scope in view of its excellent synthesis prowess as illustrated in the preparation of new-approved anti-Alzheimer and anti-HIV medicinal compounds under greener and mild reaction conditions; catalyst could be recycled and reused five times without any loss of catalytic activity.

Recommanded Product: 3,4-Dimethoxyphenylboronic acid, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., 122775-35-3.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Fanourakis, Alexander; Williams, Benjamin D.; Paterson, Kieran J.; Phipps, Robert J. published the artcile< Enantioselective Intermolecular C-H Amination Directed by a Chiral Cation>, Product Details of C11H16O2, the main research area is heptafluorobutyl hydroxy butyl sulfamate preparation enantioselective; arylbutanol heptafluorobutyl sulfamate intermol amination rhodium catalyst.

A family of anionic variants of the best-in-class catalyst for Rh-catalyzed C-H amination, Rh2(esp)2, with which the chiral cations are associated And derived from quaternized cinchona alkaloids, has been described. These ion-paired catalysts enable high levels of enantioselectivity to be achieved in the benzylic C-H amination of substrates R(CH2)4OH (R = Ph, 1-naphthyl, 3-methylthiophen-2-yl, etc.) bearing pentyl hydroxyl groups. Addnl., the quinoline of the chiral cation appears to engage in axial ligation to the rhodium complex, providing improved yields of products RCH(NHS(O)2OCH2R1)(CH2)3OH (R1 = (CF2)2CF3) vs. Rh2(esp)2 and highlighting the dual role that the cation is playing. These results underline the potential of using chiral cations to control enantioselectivity in challenging transition-metal-catalyzed transformations.

Journal of the American Chemical Society published new progress about Amination catalysts (intermol., stereoselective). 52244-70-9 belongs to class ethers-buliding-blocks, and the molecular formula is C11H16O2, Product Details of C11H16O2.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Dupuy, Stephanie; Zhang, Ke-Feng; Goutierre, Anne-Sophie; Baudoin, Olivier published the artcile< Terminal-Selective Functionalization of Alkyl Chains by Regioconvergent Cross-Coupling>, Formula: C11H16O2, the main research area is aryl triflate alkyl bromide palladium zinc Barbier Negishi coupling; alkyl linear arene preparation; C−C coupling; alkyl bromides; homogeneous catalysis; palladium; remote functionalization.

Hydrocarbons are still the most important precursors of functionalized organic mols., which has stirred interest in the discovery of new C-H bond functionalization methods. We describe herein a new step-economical approach that enables C-C bonds to be constructed at the terminal position of linear alkanes. First, we show that secondary alkyl bromides can undergo in situ conversion into alkyl zinc bromides and regioconvergent Negishi coupling with aryl or alkenyl triflates. The use of a suitable phosphine ligand favoring Pd migration enabled the selective formation of the linear cross-coupling product. Subsequently, mixtures of secondary alkyl bromides were prepared from linear alkanes by standard bromination, and regioconvergent cross-coupling then provided access to the corresponding linear arylation product in only two steps.

Angewandte Chemie, International Edition published new progress about Alkylarenes Role: SPN (Synthetic Preparation), PREP (Preparation). 52244-70-9 belongs to class ethers-buliding-blocks, and the molecular formula is C11H16O2, Formula: C11H16O2.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Xi, Xudong; Yin, Hongfang; Jin, Xiaojun; He, You published the artcile< Extraction of Notopterygium forbesii by supercritical CO2 extraction>, Quality Control of 52244-70-9, the main research area is Notopterygium supercritical carbon dioxide extraction.

The extracting process for Notopterygium forbesii by supercritical CO2 extraction was optimized. The best conditions of the extracting essential oil from root of Notopterygium forbesii by SFE-CO2 were studied and chem. composition was determined by using the GC-MS. The optimum process was as following: the temperature of extracting technique was 50°, pressure 25 MPa, extraction time 2 h and gas flow rate 65 kg/h-1. The extracting rate of essential oil was 8.8%, about 6 times to steam distillation And 159 kinds of compound was identified from extracting essential oil, furthermore compound containing Cl, S, B, F, the Si element had not been reported in the related literature. Temperature and pressure were the key factors which affected extracting efficiency and stability of Notopterygium forbesii by supercritical CO2 extraction

Yaowu Fenxi Zazhi published new progress about Essential oils Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 52244-70-9 belongs to class ethers-buliding-blocks, and the molecular formula is C11H16O2, Quality Control of 52244-70-9.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ihndris, Ray W.; Gouck, Harry K.; Bowen, C. V. published the artcile< Effect of promising insect repellents on plastics and paints>, Application In Synthesis of 52244-70-9, the main research area is .

Action of 380 repellents on Lucite, cellulose acetate, and Vinylite after 48 h. of contact are tabulated (studies in 1946). Sixty-eight of the compounds did not change any of the plastics. Lucite was attacked by 261, cellulose acetate by 126, and Vinylite by 251. Only 99 compounds attacked all 3. Results of studies in 1953 are shown in a tabulation of effects on paint, Plexiglas, Vinylite, rayon, and Plastocel of 136 repellents which had not proved unsatisfactory since 1946 for some other reason. All but 2 compounds affected paint; one of them, octyl crotonate, affected only varnish and vinylite, and the other, 3,6,8-trimethyl-4-nonyne-3-6-diol affected only varnish. Vinylite was damaged by 107, Plexiglas by 58, rayon by 55, and Plasticel by 46. In other tests only 2 chems., 2-benzyloxynaphthalene and 2-iso-pentyloxynaphthalene, affected polyethylene, and they only slightly. Fourteen materials slightly stained nylon. In still other tests, Lucite and Plexiglas were found to differ slightly in their resistance to various agents.

United States, Agricultural Research Service, [Report] ARS published new progress about Aromatic hydrocarbons Role: BIOL (Biological Study). 52244-70-9 belongs to class ethers-buliding-blocks, and the molecular formula is C11H16O2, Application In Synthesis of 52244-70-9.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Apelt, J.; Grassmann, S.; Ligneau, X.; Pertz, H. H.; Ganellin, C. R.; Arrang, J.-M.; Schwartz, J.-C.; Schunack, W.; Stark, H. published the artcile< Search for histamine H3 receptor antagonists with combined inhibitory potency at Nτ-methyltransferase: ether derivatives>, Product Details of C11H16O2, the main research area is histamine receptor antagonist methyltransferase inhibitor aryl piperidinopropyl ether preparation.

Several compounds containing an ether moiety derived from 4-(3-piperidinopropoxy)phenylaminoquinoline derivatives, such as FUB 836, were synthesized and tested for their affinity at cloned human histamine H3 (hH3) receptors and on the inhibition of rat histamine Nτ-methyltransferase (HMT). Besides different heterocycles, e.g. nitro- or amino-substituted pyridines, quinolines, benzothiazole or pyrroline, three classes of compounds were produced: heteroaromatic 3-piperidinopropyl ethers, keto- or imino-substituted 4-(3-piperidinopropyl)phenyl ethers and 4-(3-piperidinopropyl)phenyl ethers with substituted (alkyl)aminopyridines. Whereas the (3-piperidinopropoxy)heterocycles showed only moderate activities on both test models, the 4-(3-piperidinopropoxy)phenyl derivatives were identified as potent histamine H3 receptor ligands and/or HMT inhibitors. Ki values ≤ 0.42 nM were found for the affinity to the hH3 receptor. HMT inhibitory potency was identified with IC50 values about 0.3 μM for the most potent compounds in this series. Comparison of the pyridine-containing derivatives to recently published quinoline analogs showed a decrease in potencies for the pyridines. The dual activity, H3 receptor affinity and HMT inhibition, was moderate to good. For all compounds affinities at hH3 receptors were higher than their inhibitory HMT potencies.

Pharmazie published new progress about Histamine H3 receptor antagonists. 52244-70-9 belongs to class ethers-buliding-blocks, and the molecular formula is C11H16O2, Product Details of C11H16O2.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem