Month: November 2022

On June 4, 2021, Lu, Xu; Kawazu, Ryohei; Song, Jizhou; Yoshigoe, Yusuke; Torigoe, Takeru; Kuninobu, Yoichiro published an article.Recommanded Product: 150-78-7 The title of the article was Regioselective C-H Trifluoromethylation of Aromatic Compounds by Inclusion in Cyclodextrins. And the article contained the following:

A regioselective radical C-H trifluoromethylation of aromatic compounds was developed using cyclodextrins (CDs) as additives. The C-H trifluoromethylation proceeded with high regioselectivity to afford the product in good yield, even on the gram scale. In the presence of CDs, some substrates underwent a single trifluoromethylation selectively, whereas mixtures of single- and double-trifluoromethylated products were formed in the absence of the CD. 1H NMR experiments indicated that the regioselectivity was controlled by the inclusion of a substrate inside the CD cavity. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).Recommanded Product: 150-78-7

The Article related to aromatic compound regioselective trifluoromethylation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.Recommanded Product: 150-78-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On June 4, 2021, Lu, Xu; Kawazu, Ryohei; Song, Jizhou; Yoshigoe, Yusuke; Torigoe, Takeru; Kuninobu, Yoichiro published an article.Category: ethers-buliding-blocks The title of the article was Regioselective C-H Trifluoromethylation of Aromatic Compounds by Inclusion in Cyclodextrins. And the article contained the following:

A regioselective radical C-H trifluoromethylation of aromatic compounds was developed using cyclodextrins (CDs) as additives. The C-H trifluoromethylation proceeded with high regioselectivity to afford the product in good yield, even on the gram scale. In the presence of CDs, some substrates underwent a single trifluoromethylation selectively, whereas mixtures of single- and double-trifluoromethylated products were formed in the absence of the CD. 1H NMR experiments indicated that the regioselectivity was controlled by the inclusion of a substrate inside the CD cavity. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).Category: ethers-buliding-blocks

The Article related to aromatic compound regioselective trifluoromethylation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Nagaki, Aiichiro; Uesugi, Yuki; Kim, Heejin; Yoshida, Jun-ichi published an article in 2013, the title of the article was Synthesis of Functionalized Aryl Fluorides Using Organolithium Reagents in Flow Microreactors.COA of Formula: C7H7FO And the article contains the following content:

We have developed a method for preparing aryl fluorides based on organolithium chem. in flow microreactors. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).COA of Formula: C7H7FO

The Article related to aryl fluoride preparation organolithium chem flow microreactor, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.COA of Formula: C7H7FO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On February 21, 2020, Granados, Albert; Shafir, Alexandr; Arrieta, Ana; Cossio, Fernando P.; Vallribera, Adelina published an article.COA of Formula: C8H10O2 The title of the article was Stepwise Mechanism for the Bromination of Arenes by a Hypervalent Iodine Reagent. And the article contained the following:

A mild, metal-free bromination method of arenes has been developed using the combination of bis(trifluoroacetoxy)iodobencene and trimethylsilyl bromide. In situ-formed dibromo(phenyl)-ä½?-iodane (PhIBr2) is proposed as the reactive intermediate. This methodol. using PIFA/TMSBr has been applied with success to a great number of substrates (25 examples). The treatment of mono-substituted activated arenes led to para-brominated products (2u-z) in excellent 83-96% yields. D. functional theory calculations indicate a stepwise mechanism involving a double bromine addition followed by a type II dyotropic reaction with concomitant re-aromatization of the six-membered ring. The experimental process involved the reaction of 1,4-Dimethoxybenzene(cas: 150-78-7).COA of Formula: C8H10O2

The Article related to arene bromination stepwise mechanism hypervalent iodine reagent, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.COA of Formula: C8H10O2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On October 4, 2013, Ichiishi, Naoko; Canty, Allan J.; Yates, Brian F.; Sanford, Melanie S. published an article.Computed Properties of 321-28-8 The title of the article was Cu-Catalyzed Fluorination of Diaryliodonium Salts with KF. And the article contained the following:

A mild Cu-catalyzed nucleophilic fluorination of unsym. diaryliodonium salts with KF is described. This protocol preferentially fluorinates the smaller aromatic ligand on iodine(III). The reaction exhibits a broad substrate scope and proceeds with high chemoselectivity and functional group tolerance. E.g., in presence of Cu(OTf)2 and 18-crown-6, nucleophilic fluorination of diaryliodonium salt (I) with KF gave 85% II and mesityl fluoride (99:1). DFT calculations implicate a CuI/CuIII catalytic cycle. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Computed Properties of 321-28-8

The Article related to copper catalyst nucleophilic fluorination diaryliodonium salt potassium fluoride, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.Computed Properties of 321-28-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On March 31, 2015, Dubbaka, Srinivas Reddy; Gadde, Satyanarayana; Narreddula, Venkateswara Reddy published an article.SDS of cas: 321-28-8 The title of the article was Synthesis of Aryl Fluorides from Potassium Aryltrifluoroborates and Selectfluor Mediated by Iron(III) Chloride. And the article contained the following:

The synthesis of fluorinated arenes by the iron-mediated fluorination of potassium aryltrifluoroborates with Selectfluor and potassium fluoride is described. The fluorination reaction uses com. available reagents and without requiring the addition of exogenous ligands. Fluorinated compounds were obtained in moderate to good yields under mild reaction conditions. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).SDS of cas: 321-28-8

The Article related to aryl fluoride preparation aryltrifluoroborate fluorination selectfluor iron trichloride, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.SDS of cas: 321-28-8

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On October 7, 2020, Pistritto, Vincent A.; Schutzbach-Horton, Megan E.; Nicewicz, David A. published an article.Category: ethers-buliding-blocks The title of the article was Nucleophilic Aromatic Substitution of Unactivated Fluoroarenes Enabled by Organic Photoredox Catalysis. And the article contained the following:

Nucleophilic aromatic substitution (SNAr) is a classical reaction with well-known reactivity toward electron-poor fluoroarenes. However, electron-neutral and electron-rich fluoro(hetero)arenes are considerably underrepresented. Herein, we present a method for the nucleophilic defluorination of unactivated fluoroarenes enabled by cation radical-accelerated nucleophilic aromatic substitution. The use of organic photoredox catalysis renders this method operationally simple under mild conditions and is amenable to various nucleophile classes, including azoles, amines, and carboxylic acids. Select fluorinated heterocycles can be functionalized using this method. In addition, the late-stage functionalization of pharmaceuticals is also presented. Computational studies demonstrate that the site selectivity of the reaction is dictated by arene electronics. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Category: ethers-buliding-blocks

The Article related to nucleophilic aromatic substitution unactivated fluoroarene organic photoredox catalysis, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On February 6, 2015, Fujimoto, Teppei; Ritter, Tobias published an article.Name: 1-Fluoro-2-methoxybenzene The title of the article was PhenoFluorMix: Practical Chemoselective Deoxyfluorination of Phenols. And the article contained the following:

A practical deoxyfluorination with novel deoxyfluorinating reagent PhenoFluorMix, a mixture of N,N’-1,3-bis(2,6-diisopropylphenyl)chloroimidazolium chloride and CsF, is presented. PhenoFluorMix overcomes the challenges associated with hydrolysis of PhenoFluor. PhenoFluorMix does not hydrolyze, is readily available on decagram scale, and is storable in air. In this paper, we demonstrate the practicality of the reagent and exhibit the deoxyfluorination of a variety of phenols and heterocycles. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Name: 1-Fluoro-2-methoxybenzene

The Article related to aryl halide chemoselective synthesis, phenol heterocycle deoxyfluorination phenofluormix, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.Name: 1-Fluoro-2-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem