Month: November 2022

On November 22, 2021, Yan, Penghui; Tian, Xinxin; Kennedy, Eric M.; Tkachenko, Olga Petrovna; Stockenhuber, Michael published an article.Electric Literature of 91-16-7 The title of the article was Influence of Promoters (Fe, Mo, W) on the Structural and Catalytic Properties of Ni/BEA for Guaiacol Hydrodeoxygenation. And the article contained the following:

Hydrodeoxygenation (HDO) of guaiacol was investigated over BEA supported bimetallic Ni-Fe, Ni-Mo, Ni-W catalysts in a continuous-flow reactor. The electronic properties of Ni were significantly modified following the addition of W and Fe as analyzed by XPS and TPD, which is well in line with DFT calculations, suggesting that the formation of Ni-Fe and Ni-W alloys is thermodynamically favorable while the generation of a Ni-Mo alloy is unfavored. The rate of HDO over 9 wt % Ni/BEA catalyst was significantly improved following the incorporation of small quantities (<2.2 wt %) of Mo or Fe, while the incorporation of W decreased the HDO rate. The selectivity to hydrogenation products over Ni-Fe/BEA catalyst was not altered compared to Ni/BEA during the hydrogenation of toluene, indicating the observed increase in guaiacol conversion was engendered by the promotion of the direct hydrogenolysis of guaiacol to aromatics over Ni-Fe species. The hydrogenation and HDO rates of Ni-Mo/BEA catalyst were both higher than Ni/BEA, which was attributed to the increased Ni dispersion promoted by Mo as indicated by similar TOFNi values observed over Ni/BEA and Ni-Mo/BEA. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).Electric Literature of 91-16-7

The Article related to metal promote nickel bea guaiacol hydrodeoxygenation, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Electric Literature of 91-16-7

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On November 19, 1992, Achard, Daniel; Grisoni, Serge; Hanessian, Stephen; Moutonnier, Claude; Peyronel, Jean Francois; Tabart, Michel; Truchon, Alain published a patent.Quality Control of (S)-2-(2-Methoxyphenyl)propanoic acid The title of the patent was Perhydroisoindoles, their preparation and pharmaceutical compositions containing them as substance P antagonists. And the patent contained the following:

Perhydroisoindole derivatives I [R = H or form a bond; R5 = 2- or 3-halo- or Me-substituted Ph; Z = O, NH; R1 = (un)substituted Ph, cyclohexadienyl, naphthyl, heterocyclyl; R2 = H, halo, OH, alkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, alkoxy, alkylthio, acyloxy, carboxy, (un)substituted alkoxycarbonyl, benzyloxycarbonyl, amino, acylamino; R3 = halide, OH; R4 = H, or halo if R3 = halo] and their salts, prepared by reaction of R1CHR2CO2H or R1CHR2CR6:NH (R6 = C1-4 alkoxy, MeS, EtS, PhCH2S, alkoxycarbonylmethylthio) with the corresponding perhydroisoindoles, are claimed. The preparation of isomers of I, mixtures of isomers, and their salts are claimed. The compounds are particularly interesting as substance P antagonists; tests of 3 compounds, and 29 synthetic examples are described. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Quality Control of (S)-2-(2-Methoxyphenyl)propanoic acid

The Article related to perhydroisoindole preparation substance p antagonist, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Quality Control of (S)-2-(2-Methoxyphenyl)propanoic acid

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Ether – Wikipedia,
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On October 31, 2022, Chen, Lei; Chen, Yanjiao; Dai, Xuan; Guo, Jiaming; Peng, Xinhua published an article.SDS of cas: 578-58-5 The title of the article was SBA-15 Supported Silver Catalyst for the Efficient Aerobic Oxidation of Toluene Under Solvent-Free Conditions. And the article contained the following:

Abstract: The efficient SBA-15 supported silver catalysts(Ag/SBA-15) were prepared and characterized by ICP-OES, XRD, TEM, SEM, XPS and N2 adsorption-desorption techniques. The catalysts exhibited an excellent catalytic activity for the aerobic oxidation of toluene to benzaldehyde under solvent-free conditions. Conversion of toluene and selectivity of benzaldehyde were 50% and 89% resp. over catalyst with 9.1 wt% Ag loading (10Ag/SBA-15). A wide range of substrates were tolerated under the selected reaction conditions. The kinetic study shows that the oxidation of toluene over 10Ag/SBA-15 is pseudo-first-order reaction and the activation energy Ea is 45.1 kJ/mol. A plausible mechanism involving oxygen free radicals was proposed for the aerobic oxidation reaction. Compared with the traditional method, the newly designed heterogeneous catalytic system shows better economic applicability, environmental friendliness and broader application prospects. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).SDS of cas: 578-58-5

The Article related to sba supported silver catalyst aerobic oxidation toluene, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.SDS of cas: 578-58-5

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Ether – Wikipedia,
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On April 30, 2021, Yan, Penghui; Kennedy, Eric; Stockenhuber, Michael published an article.Category: ethers-buliding-blocks The title of the article was Hydrodeoxygenation of guiacol over ion-exchanged ruthenium ZSM-5 and BEA zeolites. And the article contained the following:

Ion exchanged Ru/ZSM-5 and Ru/BEA catalysts, prepared by replacing the extra framework NH+4 cations in zeolites with Ru3+ ions, are employed for the hydrodeoxygenation of guaiacol. The performance results indicate ion-exchanged Ru zeolites, with extremely low Ru contents (�.2 wt%), possess a high intrinsic HDO activity compared to the catalysts prepared by the incipient wetness impregnation method. On the basis of TEM, FTIR, XPS and TPD anal., the NH+4 ions in zeolite were substituted by Ru species, with metal particles entered the zeolite cages and finely dispersed on the support. These ion-exchanged Ru particles exhibit a strong electronic interaction with oxygen atoms of zeolite framework with a mixed Ru(0)-Ru(III) species observed in the reduced samples. In contrast, only Ru0 was detected in the reduced impregnated Ru/ZSM-5. The partial-reduced Ru species over the ion-exchanged Ru/ZSM-5 catalyst shows a high H2 adsorption activity facilitating the hydrogenation of guaiacol to the saturated products (such as 2-methoxycyclohexanol). In addition, ion-exchanged Ru-ZSM-5 and Ru-BEA catalysts present a similar normalized cyclohexane formation rate (based on the concentration of acid sites), suggesting the acid sites play a pivotal role in the deoxygenation of 2-methoxycyclohexanol to cyclohexane. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).Category: ethers-buliding-blocks

The Article related to hydrodeoxygenation guiacol ion exchange ruthenium zeolite, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Category: ethers-buliding-blocks

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Ether – Wikipedia,
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Wang, Shuyuan; Xu, Dan; Chen, Yunlei; Zhou, Song; Zhu, Di; Wen, Xiaodong; Yang, Yong; Li, Yongwang published an article in 2020, the title of the article was Hydrodeoxygenation of anisole to benzene over an Fe2P catalyst by a direct deoxygenation pathway.Recommanded Product: 2-Methylanisole And the article contains the following content:

Developing economically viable and highly selective hydrodeoxygenation (HDO) catalysts for the C-O bond cleavage of lignin-derived aryl ethers is very important, but still challenging. Herein, a novel monometallic Fe2P catalyst was synthesized by a two-stage phosphorization method under mild conditions, which showed a high arene (benzene) selectivity of 96.7% among C6+ products with a turnover frequency of 8.2 x 10-3 mol molCO-1 s-1 in the HDO of anisole at 200掳C and ambient hydrogen pressure. Characterization results revealed that the crystal structure of the Fe2P catalyst was stable and no phosphorus loss occurred in the reduction and reaction process. The kinetic results indicated that the coverage of anisole was higher than that of H2 on the Fe2P catalyst. The anisole temperature-programmed surface reaction (anisole-TPSR) and d. functional theory (DFT) calculation results identified that the anisole HDO reaction mechanism is the direct cleavage of the Caryl-O bond of anisole to form C6H5* and CH3O* without forming the C6H5-OH-CH3 intermediate. These findings may contribute toward understanding the iron-based phosphide and guiding the catalyst design for the HDO of aryl ethers and related reactions. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Recommanded Product: 2-Methylanisole

The Article related to anisole benzene iron phosphide catalyst hydrodeoxygenation, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Recommanded Product: 2-Methylanisole

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Villanueva, Omar; Weldy, Nina Mace; Blakey, Simon B.; MacBeth, Cora E. published an article in 2015, the title of the article was Cobalt catalyzed sp3 C-H amination utilizing aryl azides.Related Products of 157869-15-3 And the article contains the following content:

A dinuclear Co(II) complex supported by a modular, tunable redox-active ligand system is capable of selective C-H amination to form N-containing 5-, 6- and 7-membered heterocycles, I [R = H, Me; R1 = H, CF3, OMe; R2 = C6H5, 4-F3CC6H4, 4-H3COC6H4, 3-pyridinyl, 1-phenylsulfonyl-1H-indol-3-yl; X = (CH2)n; n = 1, 2, 3] and 5-methoxy-2-phenyl-1H-indole from aryl azides 2-N3-5-R1C6H3(CH2)nCH(R)(R2) in good yields at low (1 mol%) catalyst loading. The reaction is tolerant of medicinally relevant heterocycles. The synthetic versatility obtained using low loadings of an earth abundant transition metal complex represents a significant advance in catalytic C-H amination technol. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Related Products of 157869-15-3

The Article related to indoline preparation, azide aryl amination cobalt catalyst, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Related Products of 157869-15-3

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Ether – Wikipedia,
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On October 13, 1994, Crespo, Andre; Fardin, Veronique; Guillaume, Jean-Marc; Malleron, Jean -Luc; Peyronel, Jean-Francois published a patent.Application of 81616-80-0 The title of the patent was Preparation of pharmaceutical perhydroisoindole derivatives as neurokinin A antagonists. And the patent contained the following:

Title compounds I (R = (substituted)Ph; R1 = (substituted)Ph, PhCh2O, (substituted)-C1-4 alkyl, (substituted)amino, (substituted)heterocyclyl, cyclohexadienyl, naphthyl, indenyl; R2 = H, halo, HO, alkyl, aminoalkyl, allylaminoalkyl, dialkylaminoalkyl, etc.; R3 = (substituted)Ph), are prepared (3AR,4R,5R,7aR)-7,7-diphenyl-4-(2-methoxyphenyl)perhydro-4,5-isoindolediol (preparation given) and 3-indolylacetic acid in CH2Cl2 were added to 1-benzotriazolylol hydrate, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide and diisopropylethylamine to give (3aR,4R,5R,7aR)-I (R1 = 3-indolyl, R2 = H, R3 – 2-(MeO)C6H4) which at 10-1000 nM on human receptor NK2 showed IC50 of 215 nM. A formulation tablet comprising I is given. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Application of 81616-80-0

The Article related to arylperhydroisoindolediol preparation neurokinin antagonist, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Application of 81616-80-0

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Ether – Wikipedia,
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On July 2, 2009, Kutzki, Olaf; Ditrich, Klaus; Bartsch, Michael published a patent.Category: ethers-buliding-blocks The title of the patent was Preparation of (s)-2-amino-1-propanol (l-alaninol) from (s)-1-methoxy-2-propylamine. And the patent contained the following:

The invention relates to a method for producing (S)-2-amino-1-propanol (L-alaninol) from (S)-1-methoxy-2-propylamine via the hydrochlorination of (S)-2-amino-1-propanol. Thus, (S)-1-methoxy-2-propylamine 53.5 g was reacted with 37% hydrochloric acid 148 g at 30-135�in N2 atmosphere at 19-30 bar for 4 h to give a viscous oily liquid at (S)-2-Amino-1-propanol hydrochloride. The experimental process involved the reaction of (S)-1-Methoxypropan-2-amine hydrochloride(cas: 1162054-86-5).Category: ethers-buliding-blocks

The Article related to methoxypropylamine hydrochloric acid aminopropanol preparation, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Category: ethers-buliding-blocks

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Ether – Wikipedia,
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On January 15, 2021, Maiti, Subhadip; Mandal, Tirtha; Dash, Barada Prasanna; Dash, Jyotirmayee published an article.Safety of 2-Methylanisole The title of the article was Site-Selective Aerobic C-H Monoacylation of Carbazoles Using Palladium Catalysis. And the article contained the following:

This manuscript describes the development of a remarkably general palladium-catalyzed monoacylation of carbazoles using toluene derivatives playing the dual role of acyl source and organic solvent. The method uses NHPI as the cocatalyst and oxygen as the sole oxidant. Interestingly, the acylation of monosubstituted N-pyridylcarbazoles takes place regioselectively at the C-8 position. The scope of the method is explored using aldehyde as the acyl source. This highly site-selective acylation proceeds through a radical process. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Safety of 2-Methylanisole

The Article related to palladium catalyzed regioselective aerobic acylation carbazole, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Safety of 2-Methylanisole

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Ether – Wikipedia,
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Yan, Penghui; Li, Molly Meng-Jung; Kennedy, Eric; Adesina, Adesoji; Zhao, Guangyu; Setiawan, Adi; Stockenhuber, Michael published an article in 2020, the title of the article was The role of acid and metal sites in hydrodeoxygenation of guaiacol over Ni/Beta catalysts.Formula: C8H10O2 And the article contains the following content:

Hydrodeoxygenation (HDO) of guaiacol over Ni metal supported on zeolites (H-Beta and H-ZSM-5) with different Si/Al ratios (12.5, 25, 175) and different metal loadings (2.3-23.4 weight%) was investigated in order to elucidate the role of catalyst acidity and the structure of Ni in the HDO reaction. Results show that the deoxygenation activity and product selectivity depend on the choice of support (acidity, pore size), level of metal loading, and reaction conditions. Guaiacol was deoxygenated in the presence of hydrogen with a maximum cyclohexane yield of 76% at a guaiacol conversion level of 100% over 15.7 weight% Ni/Beta-12.5 catalyst. Compared to Ni/ZSM-5 catalysts, Ni/Beta catalysts with mesopores facilitated the formation of coupling products (1,1′-bicyclohexyl). Under differential reaction conditions, we observed a linear relationship between deoxygenation activity and concentration of acid sites. Over catalysts containing small Ni particles, cyclohexane was formed as a result of a consecutive reduction of guaiacol to catechol and cyclohexane. At higher Ni-loading and consequently larger Ni particles, the selectivity towards cyclohexane increases with increased Ni loading. A higher concentration of nickel hydrides compared to smaller Ni sites was observed by H2-TPD and H2-FTIR over larger Ni species, and the nickel hydrides are believed to be crucial intermediates in the hydrogenation reaction. The 15.7 weight% Ni/Beta (Si/Al = 12.5) exhibits a promising HDO activity due to its good synergistic effect of hydrogenation and deoxygenation functions (high concentration nickel hydrides of and acid sites). In addition, based on the product distribution over catalysts containing mainly small Ni species and the Ni nanoparticles, two different reaction pathways were proposed, and the role of the acid sites and metal sites for each reaction route was discussed. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).Formula: C8H10O2

The Article related to guaiacol hydrodeoxygenation nickel beta catalyst acid metal site, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Formula: C8H10O2

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem