Category: 2398-37-0

Li, Xuefei; Gao, Xing; He, Chun-Yang; Zhang, Xingang published their research in Organic Letters in 2021. The article was titled 《Using Chlorotrifluoroethane for Trifluoroethylation of (Hetero)aryl Bromides and Chlorides via Nickel Catalysis》.Formula: C7H7BrO The article contains the following contents:

A nickel-catalyzed reductive cross-coupling between industrial chem. CF3CH2Cl and (hetero)aryl bromides and chlorides was reported. The reaction was synthetically simple without the preparation of arylmetals and exhibits high functional group tolerance. The utility of this protocol was demonstrated by the late-stage modification of pharmaceuticals, providing a facile route for medicinal chem. In the experiment, the researchers used 1-Bromo-3-methoxybenzene(cas: 2398-37-0Formula: C7H7BrO)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Formula: C7H7BrO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

O’Brien, Connor J.; Nicewicz, David A. published their research in Synlett in 2021. The article was titled 《Milled Dry Ice as a C1 Source for the Carboxylation of Aryl Halides》.Category: ethers-buliding-blocks The article contains the following contents:

Here, it is shown that the use of milled dry ice as a method to promote the availability of CO2 in a reaction solution, permitting practical synthesis of arylcarboxylic acids RC(O)OH (R = 4-fluoro-2,6-dimethylphenyl, naphthalen-2-yl, 1-methyl-1H-indol-5-yl, etc.). Notably, the use of milled dry ice produces marked increases in yields relative to those obtained with gaseous CO2, as previously reported in the literature. In the experimental materials used by the author, we found 1-Bromo-3-methoxybenzene(cas: 2398-37-0Category: ethers-buliding-blocks)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,ACS Catalysis included an article by Zhu, Jiancheng; Lindsay, Vincent N. G.. Application In Synthesis of 1-Bromo-3-methoxybenzene. The article was titled 《Benzimidazolyl Palladium Complexes as Highly Active and General Bifunctional Catalysts in Sustainable Cross-Coupling Reactions》. The information in the text is summarized as follows:

A mononuclear and three dinuclear benzimidazolylpalladium complexes such as I·2 PF6- were prepared I·2 PF6- was an air- and moisture-stable catalyst for Suzuki, Sonogashira, and Heck coupling reactions using 0.1-1 mol% catalyst. Changes in the tether between the 2-benzimidazolyl moiety and the pyridine moiety altered the rigidity and conformation of the ligand scaffold and significantly changed the catalytic activities of the complexes. The structures of the mononuclear palladium complex and of two dinuclear benzimidazolylpalladium complexes, including I·2 PF6-·3 MeCN, were determined by X-ray crystallog. The experimental part of the paper was very detailed, including the reaction process of 1-Bromo-3-methoxybenzene(cas: 2398-37-0Application In Synthesis of 1-Bromo-3-methoxybenzene)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Application In Synthesis of 1-Bromo-3-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Nickel-Catalyzed Reductive Cross-Coupling of Aryl Bromides with Vinyl Acetate in Dimethyl Isosorbide as a Sustainable Solvent》 was written by Su, Mincong; Huang, Xia; Lei, Chuanhu; Jin, Jian. Electric Literature of C7H7BrOThis research focused onvinyl arene heteroarene benzoheterocycle preparation green chem; aryl heteroaryl bromide vinyl acetate reductive cross coupling; dimethyl isosorbide solvent nickel catalyst. The article conveys some information:

A nickel-catalyzed reductive cross-coupling has been achieved using (hetero)aryl bromides and vinyl acetate as the coupling partners. This mild, applicable method provides a reliable access to a variety of vinyl arenes, heteroarenes, and benzoheterocycles, which should expand the chem. space of precursors to fine chems. and polymers. Importantly, a sustainable solvent, di-Me isosorbide, is used, making this protocol more attractive from the point of view of green chem. In the part of experimental materials, we found many familiar compounds, such as 1-Bromo-3-methoxybenzene(cas: 2398-37-0Electric Literature of C7H7BrO)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.Electric Literature of C7H7BrO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2019,Chemical Science included an article by Zhang, Yitao; Takale, Balaram S.; Gallou, Fabrice; Reilly, John; Lipshutz, Bruce H.. Category: ethers-buliding-blocks. The article was titled 《Sustainable ppm level palladium-catalyzed aminations in nanoreactors under mild, aqueous conditions》. The information in the text is summarized as follows:

A 1 : 1 Pd : ligand complex, [t-BuXPhos(Pd-Π-cinnamyl)]OTf, was identified as a highly robust pre-catalyst for amination reactions leading to diarylamines, where loadings of metal were typically at 1000 ppm Pd, run in water at temperatures between rt and 45 °C. The protocol was exceptionally simple, readily scaled and compared very favorably vs. traditional amination conditions. It was shown to successfully led to key intermediates associated with several physiol. active compounds In the part of experimental materials, we found many familiar compounds, such as 1-Bromo-3-methoxybenzene(cas: 2398-37-0Category: ethers-buliding-blocks)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

In 2022,Shao, Huihui; Zhao, Yao; Wang, Shuangqiang; Chen, Rizhi; Zhou, Jianrong Steve; Wu, Xiaojin published an article in Organic Letters. The title of the article was 《Reductive-Delay Heck 1,1-Diarylation of Terminal Alkenes》.Reference of 1-Bromo-3-methoxybenzene The author mentioned the following in the article:

Synthesis of 5,5-diaryl-N-(quinolin-8-yl)pentanamides such as I [R = H, Me, Ph, etc.; R1 = Ph, 4-t-BuC6H4, 4-F3CC6H4, etc.; R2 = Ph, 3-MeOC6H4, 1-naphthyl, etc.] via Pd-catalyzed, chemo- and regiocontrollable 1,1-diarylation of unactivated aliphatic alkenes with two aryl bromides was done. Under the cationic reductive-delay Heck pathway, the first aryl insertion was followed by β-H elimination, while the second aryl insertion was terminated by C-H bond formation. The results came from multiple reactions, including the reaction of 1-Bromo-3-methoxybenzene(cas: 2398-37-0Reference of 1-Bromo-3-methoxybenzene)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.Reference of 1-Bromo-3-methoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Lin, Tingzhi; Qian, Pengcheng; Wang, Yan-En; Ou, Mingjie; Jiang, Long; Zhu, Chen; Xu, Yuchuan; Xiong, Dan; Mao, Jianyou published an article in 2021. The article was titled 《Palladium-Catalyzed Direct Arylation of 2-Pyridylmethyl Silanes with Aryl Bromides》, and you may find the article in Organic Letters.Formula: C7H7BrO The information in the text is summarized as follows:

The first palladium-catalyzed direct arylation of 2-pyridylmethyl silanes with aryl bromides to generate a diverse array of aryl(2-pyridyl)-Me silane derivatives has been developed. This protocol facilitates access to various kinds of heterocycle-containing silanes in good to excellent yields (40 examples, 66-97% yield) with good functional group tolerance. The scalability of this transformation is demonstrated. In the experiment, the researchers used 1-Bromo-3-methoxybenzene(cas: 2398-37-0Formula: C7H7BrO)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.Formula: C7H7BrO

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Wang, Yuzhuo; Wang, Lei; Chen, Mingjie; Tu, Youshao; Liu, Yu; Zhang, Junliang published an article in 2021. The article was titled 《Palladium/Xu-Phos-catalyzed asymmetric carboamination towards isoxazolidines and pyrrolidines》, and you may find the article in Chemical Science.Product Details of 2398-37-0 The information in the text is summarized as follows:

An efficient palladium-catalyzed enantioselective carboamination reaction of N-Boc-O-homoallyl-hydroxylamines and N-Boc-pent-4-enylamines with aryl or alkenyl bromides was developed, delivering various substituted isoxazolidines I [R = H, Me; R1 = Ph, 3-thienyl, 2-naphthyl, etc.] and pyrrolidines II [R1 = 4-PhC6H4, 3,4-MeO2C6H3, 1-naphthyl, etc.; R2 = H, Me; R3 = Boc, Cbz] in good yields with up to 97% ee. The reaction featured mild conditions, general substrate scope and scalability. The obtained products could be transformed into chiral 1,3-aminoalc. derivatives without erosion of chirality. The newly identified Xu-Phos ligand bearing an ortho-OiPr group was responsible for the good yield and high enantioselectivity. In addition to this study using 1-Bromo-3-methoxybenzene, there are many other studies that have used 1-Bromo-3-methoxybenzene(cas: 2398-37-0Product Details of 2398-37-0) was used in this study.

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.Product Details of 2398-37-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ning, Xiaoqin; Chen, Yongke; Hu, Fangdong; Xia, Ying published their research in Organic Letters in 2021. The article was titled 《Palladium-Catalyzed Carbene Coupling Reactions of Cyclobutanone N-Sulfonylhydrazones》.Related Products of 2398-37-0 The article contains the following contents:

Described herein are the palladium-catalyzed cross-coupling reactions of cyclobutanone-derived N-sulfonylhydrazones with aryl or benzyl halides, suggesting that the metal carbene process and β-hydride elimination can smoothly occur in strained ring systems. Structurally diversified products including cyclobutenes, methylenecyclobutanes, and conjugated dienes are selectively afforded in good to excellent yields. Preliminary success in asym. carbene coupling reactions in strained ring systems has been achieved, providing a promising route for the synthesis of enantioenriched four-membered-ring mols. The results came from multiple reactions, including the reaction of 1-Bromo-3-methoxybenzene(cas: 2398-37-0Related Products of 2398-37-0)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Related Products of 2398-37-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

《Copper-catalyzed arylated etherification of 2,2-difluoroethanol and its mechanistic study》 was written by Huang, Shuaishuai; Nie, Yixue; Yang, Jingjing; Zheng, Zhanjiang; Cao, Jian; Xu, Zheng; Xu, Liwen. SDS of cas: 2398-37-0 And the article was included in Youji Huaxue in 2020. The article conveys some information:

A mild and efficient method for the preparation of difluoroethyl aryl ethers was developed by the copper-catalyzed Ullmann-type arylated etherification reaction of aryl bromides or iodides with 2,2-difluoroethanol. This reaction proceeded smoothly in the presence of CuI and 8-hydroxyquinoline/t-BuOK and has a broad substrate scope. ESI-MS anal. supported the existence of LCu(III)Ar(OR) species during this catalytic reaction. Further d. functional theory (DFT) calculations suggested a proposed mechanism of arylated etherification reaction involving oxidative addition, followed by nucleophile substitution and reductive elimination would be rational. The experimental part of the paper was very detailed, including the reaction process of 1-Bromo-3-methoxybenzene(cas: 2398-37-0SDS of cas: 2398-37-0)

1-Bromo-3-methoxybenzene(cas: 2398-37-0) can be used in chemical reaction as intermediates to obtain target materials such as dyes, pharmaceuticals, perfumes, photoinitiators and agrochemicals.SDS of cas: 2398-37-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem