Li, Xuefei; Gao, Xing; He, Chun-Yang; Zhang, Xingang published their research in Organic Letters in 2021. The article was titled 《Using Chlorotrifluoroethane for Trifluoroethylation of (Hetero)aryl Bromides and Chlorides via Nickel Catalysis》.Formula: C7H7BrO The article contains the following contents:
A nickel-catalyzed reductive cross-coupling between industrial chem. CF3CH2Cl and (hetero)aryl bromides and chlorides was reported. The reaction was synthetically simple without the preparation of arylmetals and exhibits high functional group tolerance. The utility of this protocol was demonstrated by the late-stage modification of pharmaceuticals, providing a facile route for medicinal chem. In the experiment, the researchers used 1-Bromo-3-methoxybenzene(cas: 2398-37-0Formula: C7H7BrO)
1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Formula: C7H7BrO
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem