Category: ethers-buliding-blocks

Curcuma zedoaria extract as a novel corrosion inhibitor for mild steel in 0.5 M H₂SO₄ was written by Soltani, Nasrin;Tavakkoli, Nahid;Khayatkashani, Maryam;Eslami, Elham. And the article was included in Iranian Journal of Analytical Chemistry in 2022.Reference of 33171-05-0 The following contents are mentioned in the article:

In this study, curcuma zedoaria extract was investigated as a mild steel (MS) corrosion inhibitor in 0.5 M H₂SO₄ solution by conventional methods of weight loss (WL), electrochem. impedance spectroscopy (EIS) and polarization at 25°C. The highest percentage of inhibition was obtained for the concentration of 0.5 g/l of curcuma zedoaria extract The results of polarization method showed that curcuma zedoaria extract acts as a mixed inhibitor. Examination of MS immersion time by weight loss method showed that with increasing immersion time, the inhibitory effect decreases in low concentrations of curcuma zedoaria extract but in higher concentrations of curcuma zedoaria extract (concentration 1.0 g/L), the inhibitory effect remains almost constant over time. The effect of temperature on the performance of curcuma zedoaria extract by electrochem. polarization method in the temperature range of 35-65°C shows a decrease in inhibition percentage with increasing temperature Adsorption of curcuma zedoaria extract mols. on the surface of MS at all studied temperatures follows the Langmuir adsorption isotherm. Using the results of kinetic and thermodn. calculations, the adsorption of mols. of curcuma zedoaria extract on the surface of MS phys. adsorption type was observed This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Reference of 33171-05-0).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Reference of 33171-05-0

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Ether | (C2H5)2O – PubChem

Design, synthesis, and biological evaluation of 4-(1H-1,2,3-triazol-1-yl)benzamides as HSP90 inhibitors was written by He, Tingting;Zhu, Shulei;Lu, Wei. And the article was included in Molecular Diversity.Application of 109-85-3 The following contents are mentioned in the article:

Heat shock protein 90 (HSP90) is a promising anticancer drug target, which could be employed to construct HSP90 inhibitors-based drug conjugates for selective tumor therapy. Herein, a series of 4-(1H-1,2,3-triazol-1-yl)benzamides I [R = Me, n-Bu, n-Hexyl, etc.] were rationally designed, synthesized as HSP90 inhibitors, and their structures were characterized by ¹H NMR, ¹³C NMR, and HR-MS. Preliminary HSP90 binding assay showed that compounds I [R = Bu, tetrahydrofuran-3-yl, tetrahydro-2H-pyran-4-yl, 1,1-dioxo-tetrahydrothiopyran-4-yl, 2-cis-hydroxycyclopentyl, 4-transhydroxycyclohexyl] exhibited significant HSP90α binding affinity. Among these selected compound I [R = 4-transhydroxycyclohexyl] displayed the most potent anti-proliferative activities and particularly in Capan-1 cell line. Mol. modeling studies also confirmed possible mode of interaction between 6u and the binding sites of HSP90 by hydrogen bond and hydrophobic interactions. Above all, these encouraging data indicated that compound I [R = 4-transhydroxycyclohexyl] could be used as a HSP90 inhibitor for further study and helped the recognition of the 4-(1H-1,2,3-triazol-1-yl)benzamide motif as a new scaffold for HSP90 inhibitors. This study involved multiple reactions and reactants, such as 2-Methoxyethylamine (cas: 109-85-3Application of 109-85-3).

2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Application of 109-85-3

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Bisdemethoxycurcumin suppresses human brain glioblastoma multiforme GBM 8401 cell migration and invasion via affecting NF-κB and MMP -2 and MMP -9 signaling pathway in vitro was written by Chen, Chiung-Ju;Shang, Hung-Sheng;Huang, Yuan-Li;Tien, Ni;Chen, Yung-Liang;Hsu, Sheng-Yao;Wu, Rick Sai-Chuen;Tang, Chien-Lun;Lien, Jin-Cherng;Lee, Mei-Hui;Lu, Hsu-Feng;Hsia, Te-Chun. And the article was included in Environmental Toxicology in 2022.Name: Bisdemethoxycurcumin The following contents are mentioned in the article:

Human glioblastoma (GBM) is one of the common cancer death in adults worldwide, and its metastasis will lead to difficult treatment. Finding compounds for future to develop treatment is urgent. Bisdemethoxycurcumin (BDMC), a natural product, was isolated from the rhizome of turmeric (Curcuma longa), which has been shown to against many human cancer cells. In the present study, we evaluated the antimetastasis activity of BDMC in human GBM cells. Cell proliferation, cell viability, cellular uptake, wound healing, migration and invasion, and western blotting were analyzed. Results indicated that BDMC at 1.5-3μM significantly decreased the cell proliferation by MTT assay. BDMC showed the highest uptake by cells at 3 h. After treatment of BDMC at 12-48 h significantly inhibited cell motility in GBM 8401 cells by wound healing assay. BDMC suppressed cell migration and invasion at 24 and 48 h treatment by transwell chamber assay. BDMC significantly decreased the levels of proteins associated with PI3K/Akt, Ras/MEK/ERK pathways and resulted in the decrease in the expressions of NF-κB, MMP-2, MMP-9, and N-cadherin, leading to the inhibition of cell migration and invasion. These findings suggest that BDMC may be a potential candidate for the antimetastasis of human GBM cells in the future. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Name: Bisdemethoxycurcumin).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Name: Bisdemethoxycurcumin

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Hexadentate technetium-99m bis(thiosemicarbazonato) complexes: synthesis, characterization and biodistribution was written by Kelderman, Cormac A. A.;Davey, Patrick R. W. J.;Ma, Michelle T.;de Veer, Michael;Salimova, Ekaterina;Donnelly, Paul S.;Paterson, Brett M.. And the article was included in Dalton Transactions in 2022.Safety of 2-Methoxyethylamine The following contents are mentioned in the article:

The syntheses of non-oxido/non-nitrido bis(thiosemicarbazonato)technetium(V) complexes featuring a series of alkyl and ether substituents is presented. The bis(thiosemicarbazones) were radiolabeled with technetium-99m using an optimized one-pot synthesis from [^99mTc][TcO₄]^–. Mass spectrometry and computational chem. data suggested a distorted trigonal prismatic coordination environment for the bis(thiosemicarbazonato)technetium(V) complexes by way of a bis(thiosemicarbazone)technetium(V)-oxido intermediate complex. The lipophilicities of the complexes were estimated using distribution ratios and three of the new complexes were investigated in mice using kinetic planar imaging and ex vivo biodistribution experiments and were compared to [^99mTc][TcO₄]^–. Modification of the technetium complexes with various lipophilic functional groups altered the biodistributions of the complexes in mice despite evidence suggesting limited stability of the complexes to biol. relevant conditions. The most hydrophilic complex had higher uptake in the kidneys compared to the most lipophilic, which had higher liver uptake, suggesting modification of the excretion pathways. This study involved multiple reactions and reactants, such as 2-Methoxyethylamine (cas: 109-85-3Safety of 2-Methoxyethylamine).

2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Safety of 2-Methoxyethylamine

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Hydrothermal Depolymerization of Kraft Lignins with Green C₁-C₃ Alcohol-Water Mixtures was written by Guo, Ming;Maltari, Riku;Zhang, Rui;Kontro, Jussi;Ma, Enlu;Repo, Timo. And the article was included in Energy & Fuels in 2021.Name: 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

Lignin is a potential renewable raw material for synthesis of aromatic mols. and materials. Particularly, Kraft-type lignins are abundantly available as a byproduct of wood and paper industries. Currently, there are practically no valuable products made using this highly complex polymer. Within this work, we have investigated the straightforward, high-yield depolymerization of two different tech. lignins (Indulin AT and alk. lignin) using only a mixture of green short-chain (C₁-C₃) alcs. and water as solvents. As shown here, at a temperature of 220°C, autogenous pressure, and isopropanol/water as a co-solvent medium, it is possible to cleave Kraft lignin without char-forming side reactions. The obtained so-called “light” oil contains guaiacol-based monomeric units of 23 wt % yield together with liquid oligomers of 13 wt % yield combining liquid-liquid and solid-liquid extraction Two-dimensional NMR anal. of lignin residues showed that the isopropanol/water treatment caused a marked breakdown of the intermol. β-O-4 and β-β bonds; thus, the depolymerization produced monomers and lignin residues with lower mol. weight The results suggested a synergistic effect between isopropanol and water. No sign of repolymn. reactions could be observed with this process. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Name: 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Name: 4-Hydroxy-3-methoxyphenethanol

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Efficient and Mild Reductive Amination of Carbonyl Compounds Catalyzed by Dual-Function Palladium Nanoparticles was written by Jv, Xinchun;Sun, Shuting;Zhang, Qun;Du, Muyao;Wang, Lan;Wang, Bo. And the article was included in ACS Sustainable Chemistry & Engineering in 2020.Computed Properties of C10H15NO The following contents are mentioned in the article:

Primary amines are valuable building blocks for a large number of chems., developing efficient synthetic routes toward primary amines and particularly those proceeding under mild conditions are highly desirable and rather challenging. Presented here is a highly efficient procedure enabling itself to proceed in H₂O using H₂ of 1 atm (0.1 MPa) for the reductive amination of carbonyl compounds Several palladium-based nanoparticle (Pd-NP) catalysts were prepared, and one emerged to be the most suitable and classified as nanoparticles, due to its high catalytic activity, reactions were allowed to proceed at room temperature using NH₃, and the corresponding primary amines can be afforded with yields of up to 99%. Some control reactions were carried out, revealing that H₂ is pivotal for activating the Pd-NPs. The fact that the Pd-NPs can catalyze both reductive amination of carbonyl compounds and hydrogenation of imines proves Pd-NPs to be a dual-function catalyst, and a plausible mechanism was proposed. A dual-function catalyst promoted the reductive amination of carbonyl compounds with high efficiency using NH₃·H₂O and H₂ (1 atm) under mild conditions and generated H₂O as the sole byproduct. This study involved multiple reactions and reactants, such as N-(3-Methoxybenzyl)ethanamine (cas: 140715-61-3Computed Properties of C10H15NO).

N-(3-Methoxybenzyl)ethanamine (cas: 140715-61-3) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Computed Properties of C10H15NO

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Ether – Wikipedia,
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The effect of diphenyliodonium iodide treatment on bisdemethoxycurcumin accumulation in fresh-cut yam was written by Guo, Shuang;Ma, Yue;Liang, Hao;Zhao, Xiaoyan;Wang, Dan. And the article was included in International Journal of Food Science and Technology in 2022.Safety of Bisdemethoxycurcumin The following contents are mentioned in the article:

Yellowing is a main discoloration in fresh-cut yam, which reduces consumer acceptance and, hence, the commodity value. Bisdemethoxycurcumin has been demonstrated to play important roles in fresh-cut yam yellowing. Considering the pharmacol. properties and application in fruits and vegetables of diphenyliodonium iodide (DPI), the effects and mechanism of DPI treatment on bisdemethoxycurcumin accumulation in fresh-cut yam were analyzed. The results showed that total bisdemethoxycurcumin in fresh-cut yam treated with DPI was markedly inhibited due to the significantly weakened phenylpropanoid pathway and bisdemethoxycurcumin biosynthesis. DPI was found to suppress the activities of major enzymes (phenylalanine ammonia lyase, PAL, cinnamate-4 hydroxylase, C4H; 4-coumarate CoA ligase, 4CL), limit the levels of PAL, C4H and 4CL transcription and lower the contents of related metabolites in fresh-cut yam. Moreover, treatment with DPI inhibitor restrained the downstream transcription level of curcumin synthase (CURS), which had a significant impact on bisdemethoxycurcumin synthesis. Thus, our results confirmed that DPI was essential for inhibiting bisdemethoxycurcumin accumulation in fresh-cut yam through suppressed phenylpropanoid pathway and bisdemethoxycurcumin biosynthesis. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Safety of Bisdemethoxycurcumin).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Safety of Bisdemethoxycurcumin

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Impact of light-activated curcumin and curcuminoids films for catheters decontamination was written by Zangirolami, Amanda Cristina;Carbinatto, Fernanda;Filho, Jose Dirceu Vollet;Bagnato, Vanderlei Salvador;Blanco, Kate Cristina. And the article was included in Colloids and Surfaces, B: Biointerfaces in 2022.Electric Literature of C19H16O4 The following contents are mentioned in the article:

Biofilms are microbial communities protected by an extra polymeric matrix, which promotes a defense against antimicrobial agents. Cells attached in surfaces and promote infections. Photodynamic inactivation (PDI) is one of the strategies to eliminate infections due to the facility of use and the absence of resistance by bacteria. The study combines formulation with curcuminoids and with Photogem(R), illuminating them with 450 nm and 630 nm, resp. Films were prepared with pectin, glycerin, Sodium Lauryl Sulfate, curcumin, curcuminoids, or Photogem(R) (0.75; 0.75 mg/mL and 0.03 mg/mL resp.). Bacterial biofilms were formed during 3, 4, or 7 days on catheters and illumination with LED devices at 450 nm and 630 nm.The best PDI applied in S. aureus 7-days biofilm with curcuminoid film. Photogem film was the best strategy for PDI in E. coli 7-day biofilm. Curcumin film promoted similar results with S. aureus and E. coli. Light penetration demonstrated a similar decreased exponential curve along the increase of thickness of biofilm. Curcuminoids, curcumin and Photogem show efficient solubilization and availability in formulation with relevant results in PDI. S aureus biofilms were more susceptible to curcuminoid film. E coli biofilms were more susceptible to Photogem film. This study involved multiple reactions and reactants, such as Bisdemethoxycurcumin (cas: 33171-05-0Electric Literature of C19H16O4).

Bisdemethoxycurcumin (cas: 33171-05-0) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Electric Literature of C19H16O4

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ultrafine grinding of poplar biomass: effect of particle morphology on the liquefaction of biomass for methyl glycosides and phenolics was written by Zhai, Qiaolong;Li, Fanglin;Wang, Fei;Feng, Junfeng;Jiang, Jianchun;Xu, Junming. And the article was included in Cellulose (Dordrecht, Netherlands) in 2019.HPLC of Formula: 2380-78-1 The following contents are mentioned in the article:

This paper shows that mech. ultrafine grinding of poplar wood is an efficient pretreatment approach to enhance its reactivity during liquefaction. The microstructural features and chem. properties of biomass samples with different particle morphol. were studied. In particular, we found that more cellulose and hemicellulose were exposed on the outer surface of the ultrafine powder (cellular scale of plant) and the crystal lattice structure of cellulose was significantly damaged. As a result, the degree of liquefaction reached 92.03% at 180° using UP feedstock, largely exceeding the value (53.35%) obtained at the same temperature using PS0.25. Two groups of value-added chems., namely phenolics and Me glycosides were obtained during liquefaction. At 180°C, the yields of Me glycosides and phenolics obtained from an UP feedstock were, resp., 28.45% and 10.17% higher than those obtained from the PS0.25. In addition, a high degree of liquefaction (> 90%) could be obtained at a temperature 40° lower than the one required by PS0.25, greatly reducing the occurrence of side reactions and improving the purity of target products. Overall, the mech. fragmentation of biomass at cellular scale is a promising pretreatment method allowing high valorization of the entire biomass. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1HPLC of Formula: 2380-78-1).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.HPLC of Formula: 2380-78-1

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Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Potential use of corn leaf waste for biofuel production in Jordan (physio-chemical study) was written by Amer, Mohammad W.;Aljariri Alhesan, Jameel S.;Ibrahim, Sawsan;Qussay, Ghadeer;Marshall, Marc;Al-Ayed, Omar S.. And the article was included in Energy (Oxford, United Kingdom) in 2021.Recommanded Product: 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

The increase in energy demand, especially in Jordan, has encouraged researchers to consider alternative sources of energy, such as biofuel production from agricultural waste. For this study, Jordanian corn leaf waste was characterized by ultimate and proximate anal., TGA, FTIR and solid state 13C NMR. The waste showed high volatile matter, high at. H/C ratio and high O content. The corn leaf waste contained 32.1 wt% cellulose, 18.1 wt% hemicelluloses and 11.9 wt% lignin. The FTIR and 13C NMR spectrums showed high concentrations of aliphatic and carbonyl carbon. The corn leaf waste was pyrolyzed in a temperature range of 300-450°C under a constant flow rate of nitrogen. Higher oil yield was obtained at pyrolysis temperature of 450°C. The gas yield and higher heating value of the product increased as the temperature increased, whereas the water content decreased. The biofuels were rich in carbon and had a high oxygen content, which decreased as the temperature increased. The 1H NMR confirmed the markedly aliphatic character of the biofuel. The GC-MS for the biofuel indicated the presence of hydrocarbon series, large amounts of oxygenated compounds and a few nitrogen and sulfur compounds The simulated distillation showed a high proportion of diesel fraction (57-73%). This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Recommanded Product: 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: 4-Hydroxy-3-methoxyphenethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem