Efficient and Mild Reductive Amination of Carbonyl Compounds Catalyzed by Dual-Function Palladium Nanoparticles was written by Jv, Xinchun;Sun, Shuting;Zhang, Qun;Du, Muyao;Wang, Lan;Wang, Bo. And the article was included in ACS Sustainable Chemistry & Engineering in 2020.Computed Properties of C10H15NO The following contents are mentioned in the article:
Primary amines are valuable building blocks for a large number of chems., developing efficient synthetic routes toward primary amines and particularly those proceeding under mild conditions are highly desirable and rather challenging. Presented here is a highly efficient procedure enabling itself to proceed in H2O using H2 of 1 atm (0.1 MPa) for the reductive amination of carbonyl compounds Several palladium-based nanoparticle (Pd-NP) catalysts were prepared, and one emerged to be the most suitable and classified as nanoparticles, due to its high catalytic activity, reactions were allowed to proceed at room temperature using NH3, and the corresponding primary amines can be afforded with yields of up to 99%. Some control reactions were carried out, revealing that H2 is pivotal for activating the Pd-NPs. The fact that the Pd-NPs can catalyze both reductive amination of carbonyl compounds and hydrogenation of imines proves Pd-NPs to be a dual-function catalyst, and a plausible mechanism was proposed. A dual-function catalyst promoted the reductive amination of carbonyl compounds with high efficiency using NH3·H2O and H2 (1 atm) under mild conditions and generated H2O as the sole byproduct. This study involved multiple reactions and reactants, such as N-(3-Methoxybenzyl)ethanamine (cas: 140715-61-3Computed Properties of C10H15NO).
N-(3-Methoxybenzyl)ethanamine (cas: 140715-61-3) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Computed Properties of C10H15NO
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem