Tag: 100-200

Wang, Shuyuan; Xu, Dan; Chen, Yunlei; Zhou, Song; Zhu, Di; Wen, Xiaodong; Yang, Yong; Li, Yongwang published an article in 2020, the title of the article was Hydrodeoxygenation of anisole to benzene over an Fe2P catalyst by a direct deoxygenation pathway.Recommanded Product: 2-Methylanisole And the article contains the following content:

Developing economically viable and highly selective hydrodeoxygenation (HDO) catalysts for the C-O bond cleavage of lignin-derived aryl ethers is very important, but still challenging. Herein, a novel monometallic Fe2P catalyst was synthesized by a two-stage phosphorization method under mild conditions, which showed a high arene (benzene) selectivity of 96.7% among C6+ products with a turnover frequency of 8.2 x 10-3 mol molCO-1 s-1 in the HDO of anisole at 200掳C and ambient hydrogen pressure. Characterization results revealed that the crystal structure of the Fe2P catalyst was stable and no phosphorus loss occurred in the reduction and reaction process. The kinetic results indicated that the coverage of anisole was higher than that of H2 on the Fe2P catalyst. The anisole temperature-programmed surface reaction (anisole-TPSR) and d. functional theory (DFT) calculation results identified that the anisole HDO reaction mechanism is the direct cleavage of the Caryl-O bond of anisole to form C6H5* and CH3O* without forming the C6H5-OH-CH3 intermediate. These findings may contribute toward understanding the iron-based phosphide and guiding the catalyst design for the HDO of aryl ethers and related reactions. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).Recommanded Product: 2-Methylanisole

The Article related to anisole benzene iron phosphide catalyst hydrodeoxygenation, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Recommanded Product: 2-Methylanisole

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On April 30, 2021, Yan, Penghui; Kennedy, Eric; Stockenhuber, Michael published an article.Category: ethers-buliding-blocks The title of the article was Hydrodeoxygenation of guiacol over ion-exchanged ruthenium ZSM-5 and BEA zeolites. And the article contained the following:

Ion exchanged Ru/ZSM-5 and Ru/BEA catalysts, prepared by replacing the extra framework NH+4 cations in zeolites with Ru3+ ions, are employed for the hydrodeoxygenation of guaiacol. The performance results indicate ion-exchanged Ru zeolites, with extremely low Ru contents (�.2 wt%), possess a high intrinsic HDO activity compared to the catalysts prepared by the incipient wetness impregnation method. On the basis of TEM, FTIR, XPS and TPD anal., the NH+4 ions in zeolite were substituted by Ru species, with metal particles entered the zeolite cages and finely dispersed on the support. These ion-exchanged Ru particles exhibit a strong electronic interaction with oxygen atoms of zeolite framework with a mixed Ru(0)-Ru(III) species observed in the reduced samples. In contrast, only Ru0 was detected in the reduced impregnated Ru/ZSM-5. The partial-reduced Ru species over the ion-exchanged Ru/ZSM-5 catalyst shows a high H2 adsorption activity facilitating the hydrogenation of guaiacol to the saturated products (such as 2-methoxycyclohexanol). In addition, ion-exchanged Ru-ZSM-5 and Ru-BEA catalysts present a similar normalized cyclohexane formation rate (based on the concentration of acid sites), suggesting the acid sites play a pivotal role in the deoxygenation of 2-methoxycyclohexanol to cyclohexane. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).Category: ethers-buliding-blocks

The Article related to hydrodeoxygenation guiacol ion exchange ruthenium zeolite, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On October 31, 2022, Chen, Lei; Chen, Yanjiao; Dai, Xuan; Guo, Jiaming; Peng, Xinhua published an article.SDS of cas: 578-58-5 The title of the article was SBA-15 Supported Silver Catalyst for the Efficient Aerobic Oxidation of Toluene Under Solvent-Free Conditions. And the article contained the following:

Abstract: The efficient SBA-15 supported silver catalysts(Ag/SBA-15) were prepared and characterized by ICP-OES, XRD, TEM, SEM, XPS and N2 adsorption-desorption techniques. The catalysts exhibited an excellent catalytic activity for the aerobic oxidation of toluene to benzaldehyde under solvent-free conditions. Conversion of toluene and selectivity of benzaldehyde were 50% and 89% resp. over catalyst with 9.1 wt% Ag loading (10Ag/SBA-15). A wide range of substrates were tolerated under the selected reaction conditions. The kinetic study shows that the oxidation of toluene over 10Ag/SBA-15 is pseudo-first-order reaction and the activation energy Ea is 45.1 kJ/mol. A plausible mechanism involving oxygen free radicals was proposed for the aerobic oxidation reaction. Compared with the traditional method, the newly designed heterogeneous catalytic system shows better economic applicability, environmental friendliness and broader application prospects. The experimental process involved the reaction of 2-Methylanisole(cas: 578-58-5).SDS of cas: 578-58-5

The Article related to sba supported silver catalyst aerobic oxidation toluene, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.SDS of cas: 578-58-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On November 19, 1992, Achard, Daniel; Grisoni, Serge; Hanessian, Stephen; Moutonnier, Claude; Peyronel, Jean Francois; Tabart, Michel; Truchon, Alain published a patent.Quality Control of (S)-2-(2-Methoxyphenyl)propanoic acid The title of the patent was Perhydroisoindoles, their preparation and pharmaceutical compositions containing them as substance P antagonists. And the patent contained the following:

Perhydroisoindole derivatives I [R = H or form a bond; R5 = 2- or 3-halo- or Me-substituted Ph; Z = O, NH; R1 = (un)substituted Ph, cyclohexadienyl, naphthyl, heterocyclyl; R2 = H, halo, OH, alkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, alkoxy, alkylthio, acyloxy, carboxy, (un)substituted alkoxycarbonyl, benzyloxycarbonyl, amino, acylamino; R3 = halide, OH; R4 = H, or halo if R3 = halo] and their salts, prepared by reaction of R1CHR2CO2H or R1CHR2CR6:NH (R6 = C1-4 alkoxy, MeS, EtS, PhCH2S, alkoxycarbonylmethylthio) with the corresponding perhydroisoindoles, are claimed. The preparation of isomers of I, mixtures of isomers, and their salts are claimed. The compounds are particularly interesting as substance P antagonists; tests of 3 compounds, and 29 synthetic examples are described. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Quality Control of (S)-2-(2-Methoxyphenyl)propanoic acid

The Article related to perhydroisoindole preparation substance p antagonist, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Quality Control of (S)-2-(2-Methoxyphenyl)propanoic acid

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On November 22, 2021, Yan, Penghui; Tian, Xinxin; Kennedy, Eric M.; Tkachenko, Olga Petrovna; Stockenhuber, Michael published an article.Electric Literature of 91-16-7 The title of the article was Influence of Promoters (Fe, Mo, W) on the Structural and Catalytic Properties of Ni/BEA for Guaiacol Hydrodeoxygenation. And the article contained the following:

Hydrodeoxygenation (HDO) of guaiacol was investigated over BEA supported bimetallic Ni-Fe, Ni-Mo, Ni-W catalysts in a continuous-flow reactor. The electronic properties of Ni were significantly modified following the addition of W and Fe as analyzed by XPS and TPD, which is well in line with DFT calculations, suggesting that the formation of Ni-Fe and Ni-W alloys is thermodynamically favorable while the generation of a Ni-Mo alloy is unfavored. The rate of HDO over 9 wt % Ni/BEA catalyst was significantly improved following the incorporation of small quantities (<2.2 wt %) of Mo or Fe, while the incorporation of W decreased the HDO rate. The selectivity to hydrogenation products over Ni-Fe/BEA catalyst was not altered compared to Ni/BEA during the hydrogenation of toluene, indicating the observed increase in guaiacol conversion was engendered by the promotion of the direct hydrogenolysis of guaiacol to aromatics over Ni-Fe species. The hydrogenation and HDO rates of Ni-Mo/BEA catalyst were both higher than Ni/BEA, which was attributed to the increased Ni dispersion promoted by Mo as indicated by similar TOFNi values observed over Ni/BEA and Ni-Mo/BEA. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).Electric Literature of 91-16-7

The Article related to metal promote nickel bea guaiacol hydrodeoxygenation, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Electric Literature of 91-16-7

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Yan, Penghui; Tian, Xinxin; Kennedy, Eric M.; Stockenhuber, Michael published an article in 2022, the title of the article was The role of Ni sites located in mesopores in the selectivity of anisole hydrodeoxygenation.Safety of 1,2-Dimethoxybenzene And the article contains the following content:

A highly dispersed Ni catalyst with an increased number of Ni sites selectively distributed in the mesopores of HBEA has been developed and applied in anisole hydrodeoxygenation (HDO) in a continuous-flow reactor under a high WHSV (2.8 min-1). The developed catalyst (Ni/BEA-OR-PH) displayed a significantly higher cyclohexane formation rate compared to the catalysts prepared by incipient wetness impregnation (Ni/BEA-IWI) and deposition-precipitation (Ni/BEA-DP) methods, which was attributed to its higher number of accessible active metal sites in mesopores. While the Ni/BEA-DP as well as Ni/BEA-OR-PH exhibited a high dispersion, a higher concentration of Ni species was located in micropores and distributed as charge-compensating cations, leading to a low concentration of high-temperature desorbed H per surface Ni, which facilitates the hydrogenolysis activity but restricts the hydrogenation of aromatics Therefore, a high yield of BTX (benzene, toluene and xylene isomers) products was detected over Ni/BEA-DP. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).Safety of 1,2-Dimethoxybenzene

The Article related to anisole hydrodeoxygenation mesopore nickel catalyst, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Safety of 1,2-Dimethoxybenzene

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On March 10, 1994, Tabart, M.; Peyronel, J. F. published an article.Application of 81616-80-0 The title of the article was Synthesis of RPR 100893, prototype of a new series of potent and selective nonpeptide NK1 antagonists: the triarylperhydroisoindolols. And the article contained the following:

The synthesis of enantiomerically pure RPR 100893 [(3aS,4S,7aS)-I] was described. One step involved coupling of 2 chiral moieties by an acylation reaction. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Application of 81616-80-0

The Article related to rpr100893 enantiomer, isoindolol triarylperhydro, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Application of 81616-80-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On June 5, 1991, Dubroeucq, Marie Christine; Moutonnier, Claude; Peyronel, Jean Francois; Tabart, Michel; Truchon, Alain published a patent.Category: ethers-buliding-blocks The title of the patent was Isoindolone derivatives, useful as intermediates for substance P antagonists, and their preparation. And the patent contained the following:

Title compounds I [both R = H; or RR = bond; R1 = H, easily removed radical; R2 = (identically) Ph substituted optionally by halo or Me in ortho or meta position] (II), especially the (3aRS,7aRS)- and (3aR,7aR)-isomers, are prepared as intermediates for I [R1 = C(X)CHR3R4; X = O, S, NR5; R3 = (substituted) Ph, cyclohexadienyl, naphthyl, heterocyclyl; R4 = H, halo, OH, alkyl, aminoalyl, alkoxy, CO2H, amino, etc.; R5 = H, (substituted) alkyl, dialkylamino] (III), which are antagonists of substance P (no data) were prepared Cyclocondensation of 4,4-diphenyl-2-cyclohexen-1-one with PhCH2N(CH2OBu)CH2SiMe3 in CH2Cl2 in the presence of CF3CO2H gave (3aRS,7aRS)-I (R = H, R1 = CH2Ph, R2 = Ph); this was debenzylated by H over Pd/C in MeOH-HCl and the product (R2 = H) amidated by PhCH2CO2H using N,N’-carbonyldiimidazole and Et3N in CH2Cl2 to give (3aRS,7aRS)-I (R = H, R1 = COCH2Ph, R2 = Ph). Seventeen syntheses of II and 24 of III are described. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Category: ethers-buliding-blocks

The Article related to isoindolone intermediate substance p antagonist, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On November 19, 1992, Achard, Daniel; Grisoni, Serge; Hanessian, Stephen; Moutonnier, Claude; Peyronel, Jean Francois; Tabart, Michel; Truchon, Alain published a patent.Electric Literature of 81616-80-0 The title of the patent was Preparation of N-acyltetrahydroisoindoles as drugs. And the patent contained the following:

Title compounds [I; R1 = H; R1R1 = bond; R2 = Ph, halophenyl, tolyl; R3 = halo, OH; R4 = H, halo; R5 = C(:X)CHRR’; R = Ph, alkyl, alkoxy, heterocyclyl, etc.; R’ = H, halo, OH, alkyl, etc.; X = O, NH] were prepared as substance P antagonists (no data). Thus, 4,4-diphenyl-2-cyclohexenone was cyclocondensed with PhCH2N(CH2OBu)CH2SiMe3 and the product converted in 7 steps to fluorotetrahydroisoindole (R,R,R)-II (III; R5 = H) which was N-acylated by 2-[Me2N(CH2)3O]C6H4CH2CO2H (preparation given) to give III.HCl [R5 = COCH2C6H4[O(CH2)3NMe2]-2]. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Electric Literature of 81616-80-0

The Article related to isoindole acyltetrahydro substance p antagonist, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Electric Literature of 81616-80-0

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

On April 13, 1995, Garret, Claude; Louvel, Erik published a patent.Recommanded Product: (S)-2-(2-Methoxyphenyl)propanoic acid The title of the patent was Preparation of perhydroisoindole antiemetics. And the patent contained the following:

The title compounds [I; R = (un)substituted Ph; R1 = (un)substituted Ph, cyclohexadienyl, naphthyl, indenyl, (un)substituted heterocyclyl; R2 = H, halogen, OH, alkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, alkyloxy, alkylthio, acyloxy, CO2H, (un)substituted alkyloxycarbonyl, benzyloxycarbonyl, NH2, acylamino; R3 = (un)substituted Ph; R4 = OH or F if R5 = H; etc.] [e.g., (3aS,4S,7aS)-7,7-diphenyl-4-(2-methoxyphenyl)-2-tert-butoxycarbonyl-4-perhydroisoindolol], useful as antiemetics, are prepared and I-containing formulations presented. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Recommanded Product: (S)-2-(2-Methoxyphenyl)propanoic acid

The Article related to perhydroisoindole preparation antiemetic, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Recommanded Product: (S)-2-(2-Methoxyphenyl)propanoic acid

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem