On April 13, 1995, Garret, Claude; Louvel, Erik published a patent.Recommanded Product: (S)-2-(2-Methoxyphenyl)propanoic acid The title of the patent was Preparation of perhydroisoindole antiemetics. And the patent contained the following:
The title compounds [I; R = (un)substituted Ph; R1 = (un)substituted Ph, cyclohexadienyl, naphthyl, indenyl, (un)substituted heterocyclyl; R2 = H, halogen, OH, alkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, alkyloxy, alkylthio, acyloxy, CO2H, (un)substituted alkyloxycarbonyl, benzyloxycarbonyl, NH2, acylamino; R3 = (un)substituted Ph; R4 = OH or F if R5 = H; etc.] [e.g., (3aS,4S,7aS)-7,7-diphenyl-4-(2-methoxyphenyl)-2-tert-butoxycarbonyl-4-perhydroisoindolol], useful as antiemetics, are prepared and I-containing formulations presented. The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Recommanded Product: (S)-2-(2-Methoxyphenyl)propanoic acid
The Article related to perhydroisoindole preparation antiemetic, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Recommanded Product: (S)-2-(2-Methoxyphenyl)propanoic acid
Referemce:
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